Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR9632Btlr/Mmmh
Stock Number:
069425-MU
Citation ID:
RRID:MMRRC_069425-MU
Other Names:
R9632 (G1)
Major Collection:

Strain Information

Suz12
Name: SUZ12 polycomb repressive complex 2 subunit
Synonyms: 2610028O16Rik, D11Ertd530e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 52615
Homologene: 32256
Ptprz1
Name: protein tyrosine phosphatase receptor type Z, polypeptide 1
Synonyms: DSD-1-PG, phosphacan, PTPzeta, PTPbeta, Rptpbeta, Ptpz, Ptprz, RPTPz
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 19283
HGNC: HGNC:9685
Homologene: 2136
Sez6
Name: seizure related gene 6
Synonyms: sez-6, D11Bhm177e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20370
Homologene: 10948
Nrg1
Name: neuregulin 1
Synonyms: HGL, HRG, Hgl, SMDF, GGF, ARIA, heregulin, D230005F13Rik, HRGalpha, 6030402G23Rik, GGFII, NDF
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 211323
HGNC: HGNC:7997
Homologene: 138451
Sash1
Name: SAM and SH3 domain containing 1
Synonyms: A330076K04Rik, 1100001C18Rik, 2500002E12Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70097
Homologene: 69182
Polr1f
Name: RNA polymerase I subunit F
Synonyms: D16Wsu83e, 2810024J17Rik, Twistnb
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 28071
VEGA: 12
Homologene: 45411
Cuedc1
Name: CUE domain containing 1
Synonyms: C330016O16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103841
Homologene: 9933
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 28,778,039 bp (GRCm38)
  • T to C, chromosome 1 at 138,080,889 bp (GRCm38)
  • T to G, chromosome 2 at 11,481,298 bp (GRCm38)
  • T to C, chromosome 2 at 14,035,867 bp (GRCm38)
  • A to T, chromosome 2 at 14,117,393 bp (GRCm38)
  • A to T, chromosome 2 at 20,661,938 bp (GRCm38)
  • G to A, chromosome 2 at 76,884,553 bp (GRCm38)
  • A to T, chromosome 2 at 76,919,866 bp (GRCm38)
  • A to T, chromosome 2 at 88,592,713 bp (GRCm38)
  • T to C, chromosome 2 at 89,171,408 bp (GRCm38)
  • T to C, chromosome 2 at 89,362,721 bp (GRCm38)
  • A to G, chromosome 2 at 94,378,752 bp (GRCm38)
  • A to T, chromosome 2 at 142,712,040 bp (GRCm38)
  • A to C, chromosome 2 at 165,516,256 bp (GRCm38)
  • T to A, chromosome 2 at 177,509,628 bp (GRCm38)
  • T to C, chromosome 3 at 85,871,752 bp (GRCm38)
  • T to C, chromosome 3 at 88,621,269 bp (GRCm38)
  • G to A, chromosome 3 at 95,681,780 bp (GRCm38)
  • T to A, chromosome 3 at 107,671,178 bp (GRCm38)
  • T to A, chromosome 3 at 144,577,609 bp (GRCm38)
  • T to C, chromosome 4 at 99,986,721 bp (GRCm38)
  • T to A, chromosome 4 at 100,974,895 bp (GRCm38)
  • T to A, chromosome 4 at 115,492,150 bp (GRCm38)
  • T to A, chromosome 4 at 144,272,975 bp (GRCm38)
  • C to T, chromosome 4 at 148,591,582 bp (GRCm38)
  • T to A, chromosome 4 at 149,488,684 bp (GRCm38)
  • T to C, chromosome 5 at 114,415,309 bp (GRCm38)
  • A to T, chromosome 5 at 137,298,427 bp (GRCm38)
  • T to A, chromosome 6 at 23,007,293 bp (GRCm38)
  • T to C, chromosome 6 at 108,405,520 bp (GRCm38)
  • C to T, chromosome 6 at 116,401,444 bp (GRCm38)
  • T to C, chromosome 6 at 122,707,840 bp (GRCm38)
  • T to C, chromosome 7 at 11,756,480 bp (GRCm38)
  • A to T, chromosome 7 at 12,629,826 bp (GRCm38)
  • A to G, chromosome 7 at 28,142,301 bp (GRCm38)
  • A to T, chromosome 7 at 46,265,719 bp (GRCm38)
  • T to C, chromosome 7 at 97,406,895 bp (GRCm38)
  • T to A, chromosome 7 at 105,143,958 bp (GRCm38)
  • A to G, chromosome 7 at 127,207,864 bp (GRCm38)
  • T to C, chromosome 8 at 31,917,593 bp (GRCm38)
  • A to G, chromosome 8 at 95,372,103 bp (GRCm38)
  • A to G, chromosome 8 at 104,629,688 bp (GRCm38)
  • A to T, chromosome 9 at 40,000,876 bp (GRCm38)
  • A to T, chromosome 9 at 40,984,375 bp (GRCm38)
  • A to G, chromosome 9 at 80,379,994 bp (GRCm38)
  • G to A, chromosome 9 at 108,514,383 bp (GRCm38)
  • A to T, chromosome 10 at 8,740,205 bp (GRCm38)
  • A to G, chromosome 11 at 4,219,015 bp (GRCm38)
  • G to A, chromosome 11 at 59,052,571 bp (GRCm38)
  • A to G, chromosome 11 at 62,313,171 bp (GRCm38)
  • T to C, chromosome 11 at 70,394,009 bp (GRCm38)
  • G to T, chromosome 11 at 73,213,412 bp (GRCm38)
  • G to A, chromosome 11 at 77,974,295 bp (GRCm38)
  • C to T, chromosome 11 at 80,024,922 bp (GRCm38)
  • C to A, chromosome 11 at 88,170,129 bp (GRCm38)
  • A to G, chromosome 11 at 97,551,822 bp (GRCm38)
  • A to T, chromosome 11 at 99,772,271 bp (GRCm38)
  • A to G, chromosome 11 at 100,498,246 bp (GRCm38)
  • T to A, chromosome 11 at 103,542,426 bp (GRCm38)
  • T to A, chromosome 11 at 103,823,768 bp (GRCm38)
  • T to A, chromosome 11 at 107,061,719 bp (GRCm38)
  • G to A, chromosome 12 at 33,429,724 bp (GRCm38)
  • A to G, chromosome 12 at 57,617,513 bp (GRCm38)
  • A to G, chromosome 12 at 72,304,187 bp (GRCm38)
  • A to G, chromosome 12 at 77,393,733 bp (GRCm38)
  • C to T, chromosome 12 at 91,537,635 bp (GRCm38)
  • T to C, chromosome 13 at 18,125,263 bp (GRCm38)
  • A to T, chromosome 13 at 32,971,549 bp (GRCm38)
  • T to C, chromosome 13 at 45,546,043 bp (GRCm38)
  • T to A, chromosome 13 at 48,817,816 bp (GRCm38)
  • C to A, chromosome 13 at 50,474,865 bp (GRCm38)
  • C to T, chromosome 13 at 61,004,014 bp (GRCm38)
  • A to G, chromosome 13 at 117,873,986 bp (GRCm38)
  • C to A, chromosome 14 at 25,662,987 bp (GRCm38)
  • T to C, chromosome 14 at 45,163,010 bp (GRCm38)
  • T to C, chromosome 14 at 47,531,267 bp (GRCm38)
  • C to T, chromosome 14 at 50,736,742 bp (GRCm38)
  • T to A, chromosome 14 at 53,743,453 bp (GRCm38)
  • G to A, chromosome 14 at 63,948,060 bp (GRCm38)
  • C to T, chromosome 14 at 122,464,375 bp (GRCm38)
  • A to G, chromosome 15 at 78,410,269 bp (GRCm38)
  • A to T, chromosome 15 at 91,242,648 bp (GRCm38)
  • T to C, chromosome 15 at 100,652,034 bp (GRCm38)
  • T to C, chromosome 15 at 101,736,553 bp (GRCm38)
  • A to T, chromosome 16 at 3,986,105 bp (GRCm38)
  • A to T, chromosome 16 at 22,862,594 bp (GRCm38)
  • A to G, chromosome 16 at 43,822,772 bp (GRCm38)
  • A to G, chromosome 16 at 94,333,280 bp (GRCm38)
  • T to C, chromosome 17 at 7,772,790 bp (GRCm38)
  • T to C, chromosome 17 at 21,819,126 bp (GRCm38)
  • G to C, chromosome 17 at 24,426,885 bp (GRCm38)
  • G to A, chromosome 17 at 35,508,834 bp (GRCm38)
  • G to T, chromosome 17 at 74,423,064 bp (GRCm38)
  • A to G, chromosome 17 at 88,742,104 bp (GRCm38)
  • A to T, chromosome 18 at 4,339,546 bp (GRCm38)
  • T to C, chromosome 18 at 37,422,966 bp (GRCm38)
  • A to G, chromosome 18 at 52,906,654 bp (GRCm38)
  • A to T, chromosome 18 at 82,405,978 bp (GRCm38)
  • A to G, chromosome 18 at 89,017,210 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
Gene Specific Genotyping:

To request gene-specific and other genotyping services for a strain, please contact the distribution MMRRC Center for more information.

Background Genetic Quality:

The MMRRC has developed a Genetic Quality Control pipeline using the MiniMUGA array to provide additional information to identify and validate genetic backgrounds of MMRRC strains. For more information on whether genetic background data is available, please contact MMRRC_GeneticQC@med.unc.edu. Note: that MiniMUGA genetic background data is not available on all strains, but can be ordered if desired.

Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9632 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069425-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.