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Strain Name:
C57BL/6J-MtgxR9634Btlr/Mmmh
Stock Number:
069427-MU
Citation ID:
RRID:MMRRC_069427-MU
Other Names:
R9634 (G1)
Major Collection:

Strain Information

Chd7
Name: chromodomain helicase DNA binding protein 7
Synonyms: GENA 60, GENA 47, Gena 52, Cyn, A730019I05Rik, WBE1, Whi, Todo, Obt, Mt, Lda, Flo, Edy, Dz, Cycn
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 320790
Homologene: 19067
Ptpn2
Name: protein tyrosine phosphatase, non-receptor type 2
Synonyms: Ptpt, TC-PTP
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 19255
HGNC: HGNC:9650
Homologene: 7497
Ints3
Name: integrator complex subunit 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229543
Homologene: 11309
Ncapg2
Name: non-SMC condensin II complex, subunit G2
Synonyms: Mtb, 5830426I05Rik, Luzp5, mCAP-G2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 76044
VEGA: 12
Homologene: 9820
Tex2
Name: testis expressed gene 2
Synonyms: Taz4, Def-5, 4930568E07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 21763
Homologene: 32414
Evi5
Name: ecotropic viral integration site 5
Synonyms: NB4S
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14020
HGNC: HGNC:3501
Homologene: 121902
Gas2l3
Name: growth arrest-specific 2 like 3
Synonyms: LOC237436, 8430435B07Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237436
VEGA: 10
Homologene: 18386
Wwc2
Name: WW, C2 and coiled-coil domain containing 2
Synonyms: D8Ertd594e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 52357
Homologene: 32618
Anapc7
Name: anaphase promoting complex subunit 7
Synonyms: prediabetic NOD sera-reactive autoantigen, APC7
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56317
Homologene: 10512
Vps8
Name: VPS8 CORVET complex subunit
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 209018
Homologene: 44592
Iars2
Name: isoleucine-tRNA synthetase 2, mitochondrial
Synonyms: 2010002H18Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381314
Homologene: 7118
Acaca
Name: acetyl-Coenzyme A carboxylase alpha
Synonyms: acetyl-CoA carboxylase, Acc1, LOC327983, Acac, A530025K05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 107476
HGNC: HGNC:84
Homologene: 31015
Il2ra
Name: interleukin 2 receptor, alpha chain
Synonyms: IL-2R alpha chain, CD25, Ly-43, Il2r
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16184
HGNC: HGNC:6008
Homologene: 360
Ccnb1
Name: cyclin B1
Synonyms: Cycb-4, Ccnb1-rs13
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 268697
HGNC: HGNC:1579
Homologene: 68982
Sorl1
Name: sortilin-related receptor, LDLR class A repeats-containing
Synonyms: LR11, mSorLA, 2900010L19Rik, Sorla
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20660
Homologene: 2336
Extl3
Name: exostosin-like glycosyltransferase 3
Synonyms: 2900009G18Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 54616
VEGA: 14
HGNC: HGNC:3518
Homologene: 1103
Cyc1
Name: cytochrome c-1
Synonyms: 2610002H19Rik, Cyct1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66445
VEGA: 15
HGNC: HGNC:2579
Homologene: 55617
Inpp5f
Name: inositol polyphosphate-5-phosphatase F
Synonyms: cI-27, SAC2, 5830435P03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101490
Homologene: 8962
Tbl3
Name: transducin (beta)-like 3
Synonyms: 9430070M15Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 213773
Homologene: 4711
Itpkc
Name: inositol 1,4,5-trisphosphate 3-kinase C
Synonyms: 9130023N17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233011
Homologene: 11868
Atad2b
Name: ATPase family, AAA domain containing 2B
Synonyms: 1110014E10Rik, D530031C13Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 320817
VEGA: 12
Homologene: 86351
Ythdc2
Name: YTH domain containing 2
Synonyms: 3010002F02Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240255
Homologene: 11265
Dock8
Name: dedicator of cytokinesis 8
Synonyms: 1200017A24Rik, 5830472H07Rik, A130095G14Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 76088
VEGA: 19
Homologene: 52414
Gnao1
Name: guanine nucleotide binding protein, alpha O
Synonyms: Go alpha, alphaO, Galphao
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14681
HGNC: HGNC:4389
Homologene: 39203
Dgkg
Name: diacylglycerol kinase, gamma
Synonyms: Dagk3, E430001K23Rik, 2900055E17Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 110197
HGNC: HGNC:2853
Homologene: 1029
Trim45
Name: tripartite motif-containing 45
Synonyms: 4921530N01Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229644
Homologene: 11865
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Nubpl
Name: nucleotide binding protein-like
Synonyms: 2410170E07Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 76826
Homologene: 11854
Fyb2
Name: FYN binding protein 2
Synonyms: 1700024P16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242594
Homologene: 52981
Gbp7
Name: guanylate binding protein 7
Synonyms: 9830147J24Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229900
Homologene: 138296
Tmem260
Name: transmembrane protein 260
Synonyms: 6720456H20Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218989
Homologene: 49506
Rims3
Name: regulating synaptic membrane exocytosis 3
Synonyms: Rim3, Nim3, A730060M23Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242662
Homologene: 8837
Ddx59
Name: DEAD box helicase 59
Synonyms: 4833411G06Rik, 1210002B07Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67997
Homologene: 12222
Loxl3
Name: lysyl oxidase-like 3
Synonyms: Lor2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16950
Homologene: 56591
Fktn
Name: fukutin
Synonyms: Fukutin, Fcmd
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 246179
HGNC: HGNC:3622
Homologene: 31402
Plch1
Name: phospholipase C, eta 1
Synonyms: PLCeta1, Plcl3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 269437
Homologene: 88833
Prkag2
Name: protein kinase, AMP-activated, gamma 2 non-catalytic subunit
Synonyms: 2410051C13Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 108099
HGNC: HGNC:9386
Homologene: 136125
Dpf3
Name: double PHD fingers 3
Synonyms: cer-d4, 2810403B03Rik, CERD4, Gm18872
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 70127
Homologene: 129842
Or8b51
Name: olfactory receptor family 8 subfamily B member 51
Synonyms: GA_x6K02T2PVTD-32360710-32359778, MOR168-1, Olfr916
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258780
VEGA: 9
Homologene: 74147
Poglut2
Name: protein O-glucosyltransferase 2
Synonyms: EP58, 1810049A15Rik, 5730416C13Rik, Kdel1, Kdelc1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 72050
Homologene: 11367
Paip2b
Name: poly(A) binding protein interacting protein 2B
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232164
Homologene: 25798
Kcnrg
Name: potassium channel regulator
Synonyms: LOC328424, E030012H22Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 328424
VEGA: 14
Homologene: 35259
Vwa1
Name: von Willebrand factor A domain containing 1
Synonyms: WARP, 4932416A11Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 246228
Homologene: 11270
Zfp36l2
Name: zinc finger protein 36, C3H type-like 2
Synonyms: Tis11d, ERF2, Brf2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12193
HGNC: HGNC:1108
Homologene: 5027
Or4x11
Name: olfactory receptor family 4 subfamily X member 11
Synonyms: GA_x6K02T2Q125-51469027-51469956, MOR228-2, Olfr1265
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258340
Homologene: 133727
Nkain2
Name: Na+/K+ transporting ATPase interacting 2
Synonyms: 6330571D19Rik, Tcba1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 432450
Homologene: 65073
Gja10
Name: gap junction protein, alpha 10
Synonyms: Cx-57, connexin-57, Cx59, Cx57
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14610
Homologene: 7733
Or4f4-ps1
Name: olfactory receptor family 4 subfamily F member 4, pseudogene 1
Synonyms: GA_x6K02T2Q125-72550790-72551728, MOR245-32_p, OTTMUSG00000015084, Olfr1291, Olfr1291-ps1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 257819
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 44,113,036 bp (GRCm38)
  • G to A, chromosome 1 at 136,419,476 bp (GRCm38)
  • A to G, chromosome 1 at 185,295,530 bp (GRCm38)
  • C to T, chromosome 2 at 11,680,416 bp (GRCm38)
  • C to T, chromosome 2 at 41,245,939 bp (GRCm38)
  • T to C, chromosome 2 at 90,037,563 bp (GRCm38)
  • T to C, chromosome 2 at 111,499,786 bp (GRCm38)
  • T to C, chromosome 3 at 63,697,731 bp (GRCm38)
  • T to C, chromosome 3 at 90,411,299 bp (GRCm38)
  • T to C, chromosome 3 at 100,931,990 bp (GRCm38)
  • T to A, chromosome 3 at 142,536,354 bp (GRCm38)
  • A to G, chromosome 4 at 8,832,499 bp (GRCm38)
  • A to G, chromosome 4 at 32,601,877 bp (GRCm38)
  • A to G, chromosome 4 at 53,761,230 bp (GRCm38)
  • A to T, chromosome 4 at 104,999,382 bp (GRCm38)
  • G to A, chromosome 4 at 120,891,320 bp (GRCm38)
  • G to A, chromosome 4 at 155,772,879 bp (GRCm38)
  • A to G, chromosome 5 at 24,869,240 bp (GRCm38)
  • T to C, chromosome 5 at 107,816,797 bp (GRCm38)
  • T to C, chromosome 5 at 122,422,626 bp (GRCm38)
  • C to T, chromosome 6 at 83,050,854 bp (GRCm38)
  • T to C, chromosome 6 at 83,810,041 bp (GRCm38)
  • A to G, chromosome 7 at 27,214,455 bp (GRCm38)
  • A to C, chromosome 7 at 128,676,791 bp (GRCm38)
  • GCC to GCCC, chromosome 8 at 47,851,924 bp (GRCm38)
  • A to G, chromosome 8 at 93,956,095 bp (GRCm38)
  • A to G, chromosome 9 at 38,657,573 bp (GRCm38)
  • T to G, chromosome 9 at 41,996,294 bp (GRCm38)
  • G to A, chromosome 10 at 32,890,266 bp (GRCm38)
  • C to T, chromosome 10 at 89,414,081 bp (GRCm38)
  • C to A, chromosome 11 at 84,293,990 bp (GRCm38)
  • A to G, chromosome 11 at 106,568,152 bp (GRCm38)
  • T to C, chromosome 12 at 5,010,332 bp (GRCm38)
  • T to C, chromosome 12 at 52,302,711 bp (GRCm38)
  • A to G, chromosome 12 at 83,331,861 bp (GRCm38)
  • T to A, chromosome 12 at 116,415,457 bp (GRCm38)
  • G to A, chromosome 13 at 100,783,604 bp (GRCm38)
  • C to A, chromosome 14 at 48,472,359 bp (GRCm38)
  • CACAACAA to CACAA, chromosome 14 at 61,607,560 bp (GRCm38)
  • A to T, chromosome 14 at 65,077,470 bp (GRCm38)
  • A to G, chromosome 15 at 76,343,594 bp (GRCm38)
  • T to C, chromosome 16 at 21,554,143 bp (GRCm38)
  • T to A, chromosome 16 at 22,519,637 bp (GRCm38)
  • T to C, chromosome 17 at 24,707,557 bp (GRCm38)
  • A to G, chromosome 17 at 84,186,628 bp (GRCm38)
  • A to G, chromosome 18 at 44,872,970 bp (GRCm38)
  • C to T, chromosome 18 at 67,675,719 bp (GRCm38)
  • A to G, chromosome 19 at 25,192,221 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9634 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069427-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.