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Strain Name:
C57BL/6J-MtgxR9652Btlr/Mmmh
Stock Number:
069445-MU
Citation ID:
RRID:MMRRC_069445-MU
Other Names:
R9652 (G1)
Major Collection:

Strain Information

Sbf2
Name: SET binding factor 2
Synonyms: SBF2, 4833411B01Rik, mMTMH1, B430219L04Rik, Mtmr13
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 319934
HGNC: HGNC:2135
Homologene: 41810
Dst
Name: dystonin
Synonyms: bullous pemphigoid antigen 1, BPAG1-n, BPAG1, Bpag1, Bpag, ah, bullous pemphigoid antigen 1, athetoid, Macf2, 2310001O04Rik, nmf203, A830042E19Rik, nmf339
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Ctbp2
Name: C-terminal binding protein 2
Synonyms: D7Ertd45e, Ribeye, Gtrgeo6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13017
HGNC: HGNC:2495
Homologene: 75187
Tnpo3
Name: transportin 3
Synonyms: 5730544L10Rik, C430013M08Rik, D6Ertd313e
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 320938
Homologene: 40848
Nisch
Name: nischarin
Synonyms: 1200007D05Rik, 3202002H23Rik, edsn
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 64652
Homologene: 136161
Senp6
Name: SUMO/sentrin specific peptidase 6
Synonyms: E130319N12Rik, 2810017C20Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 215351
Homologene: 9196
Kifap3
Name: kinesin-associated protein 3
Synonyms: KAP3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16579
Homologene: 7799
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 34,180,377 bp (GRCm38)
  • A to G, chromosome 1 at 55,696,291 bp (GRCm38)
  • T to C, chromosome 1 at 163,862,088 bp (GRCm38)
  • G to T, chromosome 1 at 180,332,491 bp (GRCm38)
  • C to T, chromosome 1 at 192,846,528 bp (GRCm38)
  • C to A, chromosome 2 at 69,870,440 bp (GRCm38)
  • A to T, chromosome 2 at 86,733,292 bp (GRCm38)
  • T to C, chromosome 2 at 101,688,582 bp (GRCm38)
  • T to A, chromosome 2 at 112,409,152 bp (GRCm38)
  • T to A, chromosome 2 at 112,804,702 bp (GRCm38)
  • G to T, chromosome 2 at 127,226,039 bp (GRCm38)
  • G to A, chromosome 2 at 157,253,050 bp (GRCm38)
  • T to A, chromosome 3 at 101,883,532 bp (GRCm38)
  • G to A, chromosome 4 at 57,710,125 bp (GRCm38)
  • G to C, chromosome 4 at 121,150,668 bp (GRCm38)
  • T to C, chromosome 4 at 129,224,169 bp (GRCm38)
  • G to T, chromosome 4 at 129,595,301 bp (GRCm38)
  • T to G, chromosome 4 at 144,157,919 bp (GRCm38)
  • T to A, chromosome 4 at 154,998,485 bp (GRCm38)
  • A to G, chromosome 5 at 27,842,840 bp (GRCm38)
  • T to C, chromosome 5 at 73,414,997 bp (GRCm38)
  • A to G, chromosome 5 at 108,803,241 bp (GRCm38)
  • A to G, chromosome 5 at 129,997,811 bp (GRCm38)
  • T to C, chromosome 5 at 136,101,640 bp (GRCm38)
  • G to A, chromosome 6 at 29,560,174 bp (GRCm38)
  • A to G, chromosome 6 at 43,174,057 bp (GRCm38)
  • G to T, chromosome 6 at 126,927,563 bp (GRCm38)
  • T to G, chromosome 6 at 141,648,632 bp (GRCm38)
  • A to G, chromosome 6 at 146,626,200 bp (GRCm38)
  • A to G, chromosome 7 at 6,317,329 bp (GRCm38)
  • A to G, chromosome 7 at 55,052,832 bp (GRCm38)
  • T to C, chromosome 7 at 104,142,755 bp (GRCm38)
  • A to T, chromosome 7 at 105,126,778 bp (GRCm38)
  • G to T, chromosome 7 at 105,482,097 bp (GRCm38)
  • T to C, chromosome 7 at 110,441,495 bp (GRCm38)
  • G to T, chromosome 7 at 112,346,789 bp (GRCm38)
  • A to G, chromosome 7 at 112,955,577 bp (GRCm38)
  • A to G, chromosome 7 at 118,735,330 bp (GRCm38)
  • C to G, chromosome 7 at 133,014,204 bp (GRCm38)
  • G to T, chromosome 8 at 105,085,625 bp (GRCm38)
  • G to T, chromosome 8 at 105,254,497 bp (GRCm38)
  • T to A, chromosome 9 at 18,586,882 bp (GRCm38)
  • T to A, chromosome 9 at 80,113,946 bp (GRCm38)
  • T to A, chromosome 9 at 95,874,834 bp (GRCm38)
  • C to T, chromosome 10 at 42,197,025 bp (GRCm38)
  • A to T, chromosome 10 at 60,331,356 bp (GRCm38)
  • T to C, chromosome 10 at 79,035,396 bp (GRCm38)
  • C to A, chromosome 10 at 82,884,556 bp (GRCm38)
  • T to C, chromosome 10 at 88,489,637 bp (GRCm38)
  • T to C, chromosome 10 at 130,017,940 bp (GRCm38)
  • T to C, chromosome 11 at 55,108,938 bp (GRCm38)
  • A to G, chromosome 11 at 85,030,491 bp (GRCm38)
  • T to C, chromosome 11 at 98,435,986 bp (GRCm38)
  • A to T, chromosome 11 at 100,413,673 bp (GRCm38)
  • T to A, chromosome 12 at 61,843,632 bp (GRCm38)
  • A to G, chromosome 12 at 76,054,846 bp (GRCm38)
  • G to A, chromosome 13 at 114,884,455 bp (GRCm38)
  • A to T, chromosome 14 at 31,171,671 bp (GRCm38)
  • T to C, chromosome 14 at 64,032,265 bp (GRCm38)
  • T to C, chromosome 14 at 70,477,920 bp (GRCm38)
  • A to T, chromosome 15 at 39,760,396 bp (GRCm38)
  • G to A, chromosome 15 at 86,131,959 bp (GRCm38)
  • G to A, chromosome 15 at 99,279,735 bp (GRCm38)
  • C to T, chromosome 15 at 101,690,685 bp (GRCm38)
  • A to C, chromosome 16 at 30,309,575 bp (GRCm38)
  • T to G, chromosome 16 at 73,024,442 bp (GRCm38)
  • T to C, chromosome 17 at 19,793,765 bp (GRCm38)
  • T to A, chromosome 17 at 24,728,354 bp (GRCm38)
  • G to A, chromosome 17 at 24,884,408 bp (GRCm38)
  • C to A, chromosome 17 at 24,982,809 bp (GRCm38)
  • A to T, chromosome 17 at 25,749,068 bp (GRCm38)
  • T to C, chromosome 17 at 32,338,809 bp (GRCm38)
  • A to G, chromosome 17 at 68,842,186 bp (GRCm38)
  • A to T, chromosome 17 at 85,452,285 bp (GRCm38)
  • T to C, chromosome 18 at 47,249,185 bp (GRCm38)
  • A to T, chromosome 18 at 52,638,943 bp (GRCm38)
  • A to G, chromosome 18 at 58,013,650 bp (GRCm38)
  • G to A, chromosome 18 at 61,743,361 bp (GRCm38)
  • T to A, chromosome 18 at 63,727,755 bp (GRCm38)
  • A to G, chromosome 19 at 42,177,417 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
Gene Specific Genotyping:

To request gene-specific and other genotyping services for a strain, please contact the distribution MMRRC Center for more information.

Background Genetic Quality:

The MMRRC has developed a Genetic Quality Control pipeline using the MiniMUGA array to provide additional information to identify and validate genetic backgrounds of MMRRC strains. For more information on whether genetic background data is available, please contact MMRRC_GeneticQC@med.unc.edu. Note: that MiniMUGA genetic background data is not available on all strains, but can be ordered if desired.

Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9652 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069445-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.