Strain Name:
C57BL/6J-MtgxR9656Btlr/Mmmh
Stock Number:
069449-MU
Citation ID:
RRID:MMRRC_069449-MU
Other Names:
R9656 (G1)
Major Collection:

Strain Information

Col1a1
Name: collagen, type I, alpha 1
Synonyms: Cola-1, Col1a-1, Cola1, Mov-13
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12842
HGNC: HGNC:2197
Homologene: 73874
Satb1
Name: special AT-rich sequence binding protein 1
Synonyms: 2610306G12Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20230
Homologene: 2232
Cpe
Name: carboxypeptidase E
Synonyms: CPH, carboxypeptidase H, Cph-1, NF-alpha1, Cph1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12876
HGNC: HGNC:2303
Homologene: 48052
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: DNAPDcs, DNA-PK, slip, XRCC7, DNA-PKcs, dxnph, DOXNPH
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Rbm6
Name: RNA binding motif protein 6
Synonyms: g16, Def-3, NY-LU-12
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 19654
HGNC: HGNC:9903
Homologene: 31336
Atad5
Name: ATPase family, AAA domain containing 5
Synonyms: LOC237877, C130052G03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237877
Homologene: 32611
Ints3
Name: integrator complex subunit 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229543
Homologene: 11309
Mcm5
Name: minichromosome maintenance complex component 5
Synonyms: Cdc46, Mcmd5, mCD46
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17218
HGNC: HGNC:6948
Homologene: 4904
Atxn2
Name: ataxin 2
Synonyms: Sca2, ATX2, 9630045M23Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20239
Homologene: 2234
Tiam1
Name: T cell lymphoma invasion and metastasis 1
Synonyms: D16Ium10, D16Ium10e
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 21844
Homologene: 2443
Tbc1d13
Name: TBC1 domain family, member 13
Synonyms: 2600014A06Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 70296
Homologene: 10068
Tap1
Name: transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Synonyms: TAP, Abcb2, PSF-1, RING4, Ham1, Ham-1, Tap-1, MTP1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21354
HGNC: HGNC:43
Homologene: 495
Btnl9
Name: butyrophilin-like 9
Synonyms: D330012D11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237754
Homologene: 68540
Hspg2
Name: perlecan (heparan sulfate proteoglycan 2)
Synonyms: perlecan, Plc, Pcn, per
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 15530
HGNC: HGNC:5273
Homologene: 68473
Nfatc3
Name: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3
Synonyms: NFAT4, NFATx, D8Ertd281e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 18021
HGNC: HGNC:7777
Homologene: 27827
Rae1
Name: ribonucleic acid export 1
Synonyms: MNRP41, 41, D2Ertd342e, MNRP
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66679
HGNC: HGNC:9828
Homologene: 2676
L1td1
Name: LINE-1 type transposase domain containing 1
Synonyms: ECAT11
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 381591
Homologene: 135709
Nkx1-2
Name: NK1 homeobox 2
Synonyms: Nkx-1.2, Nkx-1.1, Sax1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20231
Homologene: 7525
Cfap46
Name: cilia and flagella associated protein 46
Synonyms: Ttc40, 9330101J02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 212124
Spmip2
Name: sperm microtubule inner protein 2
Synonyms: Gm17359
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 100233207
Homologene: 105634
Rfx8
Name: regulatory factor X 8
Synonyms: 4933400N17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 619289
Homologene: 82436
Ttn
Name: titin
Synonyms: connectin, shru, D330041I19Rik, 2310057K23Rik, mdm, D830007G01Rik, 2310074I15Rik, 1100001C23Rik, 2310036G12Rik, L56
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Ncoa6
Name: nuclear receptor coactivator 6
Synonyms: NRC, ASC2, PRIP, ASC-2, AIB3, RAP250
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 56406
Homologene: 137337
Lrp2bp
Name: Lrp2 binding protein
Synonyms: MegBP, 1700113N17Rik, 4930479L12Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67620
Homologene: 10183
Slc24a2
Name: solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
Synonyms: 6330417K15Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 76376
Homologene: 10669
Otog
Name: otogelin
Synonyms: Otgn
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18419
HGNC: HGNC:8516
Homologene: 8421
Snrpn
Name: small nuclear ribonucleoprotein N
Synonyms: Pwcr1, 2410045I01Rik, Peg4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20646
Homologene: 68297
Grin2a
Name: glutamate receptor, ionotropic, NMDA2A (epsilon 1)
Synonyms: NMDAR2A, GluN2A, GluRepsilon1, NR2A
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 14811
HGNC: HGNC:4585
Homologene: 645
Tgm7
Name: transglutaminase 7
Synonyms: TGz
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 640543
Homologene: 14192
Bsn
Name: bassoon
Synonyms: presynaptic cytomatrix protein
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12217
HGNC: HGNC:1117
Homologene: 31161
Zfp329
Name: zinc finger protein 329
Synonyms: 2810439M05Rik, 4632409L22Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67230
Homologene: 23459
Bbs10
Name: Bardet-Biedl syndrome 10
Synonyms: 1300007O09Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71769
VEGA: 10
Homologene: 49781
Fam83b
Name: family with sequence similarity 83, member B
Synonyms: C530008M07Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 208994
Homologene: 19478
Fanca
Name: Fanconi anemia, complementation group A
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14087
HGNC: HGNC:3582
Homologene: 108
Cyp2d26
Name: cytochrome P450, family 2, subfamily d, polypeptide 26
Synonyms: 1300006E06Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 76279
VEGA: 15
Homologene: 130660
Or2t44
Name: olfactory receptor family 2 subfamily T member 44
Synonyms: MOR278-2, GA_x6K02T2NKPP-622179-621244, Olfr314
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 257917
Homologene: 133891
Zfp467
Name: zinc finger protein 467
Synonyms: 1190001I08Rik, EZI, MNCb-3350
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68910
Homologene: 10758
Cckar
Name: cholecystokinin A receptor
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12425
HGNC: HGNC:1570
Homologene: 37337
Abhd13
Name: abhydrolase domain containing 13
Synonyms: 1110065L07Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 68904
Homologene: 6716
Slc5a4b
Name: solute carrier family 5 (neutral amino acid transporters, system A), member 4b
Synonyms: SAAT1, pSGLT2, SGLT3b, 2010104G07Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 64454
Homologene: 56968
Rft1
Name: RFT1 homolog
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 328370
Homologene: 5343
Or4f54
Name: olfactory receptor family 4 subfamily F member 54
Synonyms: GA_x6K02T2Q125-72343713-72344654, MOR245-11, Olfr1278
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258389
Homologene: 74061
Spata31e5
Name: spermatogenesis associated 31 subfamily E member 5
Synonyms: LOC210962, Gm597
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210962
Rbm12
Name: RNA binding motif protein 12
Synonyms: SWAN, 5730420G12Rik, 9430070C08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 75710
HGNC: HGNC:9898
Homologene: 34993
Or5b21
Name: olfactory receptor family 5 subfamily B member 21
Synonyms: MOR202-4, Olfr1444, GA_x6K02T2RE5P-3191201-3192160
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258697
Homologene: 64906
Gstm1
Name: glutathione S-transferase, mu 1
Synonyms: Gstb-1, Gstb1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14862
Homologene: 115474
Ccn5
Name: cellular communication network factor 5
Synonyms: Crgr4, rCop1, CCN5, Wisp2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22403
Homologene: 2882
Pygm
Name: muscle glycogen phosphorylase
Synonyms: PG
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 19309
HGNC: HGNC:9726
Homologene: 2145
Krt12
Name: keratin 12
Synonyms: Krt1-12, K12
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268482
HGNC: HGNC:6414
Homologene: 188
Spata33
Name: spermatogenesis associated 33
Synonyms: 4732415M23Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 320869
Homologene: 51900
Vmn1r43
Name: vomeronasal 1 receptor 43
Synonyms: V1ra5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113847
Homologene: 130651
Hace1
Name: HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
Synonyms: A730034A22Rik, 1700042J16Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 209462
Homologene: 10807
Rd3l
Name: retinal degeneration 3-like
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217874
Homologene: 19151
Fam114a1
Name: family with sequence similarity 114, member A1
Synonyms: 1190001N04Rik, 9130005N14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 68303
Homologene: 12259
Grpel2
Name: GrpE-like 2, mitochondrial
Synonyms: mt-GrpE#2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 17714
VEGA: 18
Homologene: 41432
Or5b110-ps1
Name: olfactory receptor family 5 subfamily B member 110, pseudogene 1
Synonyms: Olfr1464-ps1, GA_x6K02T2RE5P-3614075-3613153, Gm8561, MOR202-27P
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 667300
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • G to T, chromosome 1 at 28,777,455 bp (GRCm38)
  • T to C, chromosome 1 at 39,670,519 bp (GRCm38)
  • C to T, chromosome 2 at 30,142,417 bp (GRCm38)
  • C to T, chromosome 2 at 76,885,013 bp (GRCm38)
  • A to T, chromosome 2 at 111,292,288 bp (GRCm38)
  • G to A, chromosome 2 at 121,109,710 bp (GRCm38)
  • A to G, chromosome 2 at 155,432,926 bp (GRCm38)
  • A to T, chromosome 2 at 156,098,201 bp (GRCm38)
  • A to G, chromosome 2 at 163,829,065 bp (GRCm38)
  • T to A, chromosome 2 at 173,012,797 bp (GRCm38)
  • T to A, chromosome 3 at 79,405,876 bp (GRCm38)
  • T to C, chromosome 3 at 90,392,532 bp (GRCm38)
  • T to C, chromosome 3 at 108,017,756 bp (GRCm38)
  • T to C, chromosome 4 at 87,049,907 bp (GRCm38)
  • T to C, chromosome 4 at 98,733,986 bp (GRCm38)
  • T to C, chromosome 4 at 137,551,885 bp (GRCm38)
  • A to G, chromosome 5 at 53,699,976 bp (GRCm38)
  • T to C, chromosome 5 at 65,005,903 bp (GRCm38)
  • C to T, chromosome 5 at 121,783,998 bp (GRCm38)
  • T to A, chromosome 6 at 48,442,669 bp (GRCm38)
  • A to T, chromosome 6 at 89,870,458 bp (GRCm38)
  • A to T, chromosome 7 at 12,810,490 bp (GRCm38)
  • A to G, chromosome 7 at 46,310,143 bp (GRCm38)
  • A to T, chromosome 7 at 59,985,967 bp (GRCm38)
  • T to A, chromosome 7 at 132,599,499 bp (GRCm38)
  • A to T, chromosome 7 at 139,655,900 bp (GRCm38)
  • G to A, chromosome 8 at 9,987,991 bp (GRCm38)
  • A to G, chromosome 8 at 46,013,121 bp (GRCm38)
  • T to C, chromosome 8 at 64,594,946 bp (GRCm38)
  • C to T, chromosome 8 at 75,117,540 bp (GRCm38)
  • G to A, chromosome 8 at 106,104,134 bp (GRCm38)
  • A to T, chromosome 8 at 123,222,019 bp (GRCm38)
  • A to C, chromosome 8 at 123,304,743 bp (GRCm38)
  • A to G, chromosome 9 at 76,545,581 bp (GRCm38)
  • G to A, chromosome 9 at 107,779,579 bp (GRCm38)
  • T to A, chromosome 9 at 108,117,208 bp (GRCm38)
  • A to T, chromosome 10 at 45,671,449 bp (GRCm38)
  • C to A, chromosome 10 at 76,108,557 bp (GRCm38)
  • T to A, chromosome 10 at 111,299,684 bp (GRCm38)
  • T to C, chromosome 11 at 49,169,181 bp (GRCm38)
  • G to A, chromosome 11 at 58,786,809 bp (GRCm38)
  • G to T, chromosome 11 at 80,089,716 bp (GRCm38)
  • T to A, chromosome 11 at 94,948,546 bp (GRCm38)
  • T to C, chromosome 11 at 99,418,645 bp (GRCm38)
  • A to T, chromosome 12 at 111,980,180 bp (GRCm38)
  • A to T, chromosome 12 at 114,253,675 bp (GRCm38)
  • T to C, chromosome 14 at 30,682,757 bp (GRCm38)
  • C to A, chromosome 15 at 82,792,858 bp (GRCm38)
  • T to C, chromosome 16 at 9,579,607 bp (GRCm38)
  • T to G, chromosome 16 at 15,799,954 bp (GRCm38)
  • A to G, chromosome 16 at 89,867,571 bp (GRCm38)
  • A to G, chromosome 17 at 34,193,551 bp (GRCm38)
  • A to T, chromosome 17 at 51,805,236 bp (GRCm38)
  • G to T, chromosome 18 at 61,726,290 bp (GRCm38)
  • A to G, chromosome 19 at 6,388,157 bp (GRCm38)
  • A to G, chromosome 19 at 12,861,883 bp (GRCm38)
  • T to C, chromosome 19 at 13,282,671 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9656 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069449-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.