Strain Name:
C57BL/6J-MtgxR9671Btlr/Mmmh
Stock Number:
069464-MU
Citation ID:
RRID:MMRRC_069464-MU
Other Names:
R9671 (G1)
Major Collection:

Strain Information

Sema3e
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
Synonyms: Semah
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20349
Homologene: 8247
Dot1l
Name: DOT1 like histone lysine methyltransferase
Synonyms: KMT4, mDot1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 208266
Homologene: 32779
Knl1
Name: kinetochore scaffold 1
Synonyms: 5730505K17Rik, Casc5, 2310043D08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 76464
Homologene: 44890
Rxrb
Name: retinoid X receptor beta
Synonyms: H-2RIIBP, Rub, Nr2b2, RCoR-1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20182
Homologene: 7923
Vipas39
Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
Synonyms: SPE-39, Vipar
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 104799
VEGA: 12
Homologene: 41464
Jak1
Name: Janus kinase 1
Synonyms: C130039L05Rik, BAP004
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16451
HGNC: HGNC:6190
Homologene: 1678
Acsf2
Name: acyl-CoA synthetase family member 2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 264895
Homologene: 23519
Pkd2
Name: polycystin 2, transient receptor potential cation channel
Synonyms: PC2, polycystin-2, C030034P18Rik, TRPP2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18764
HGNC: HGNC:9009
Homologene: 20104
Sorl1
Name: sortilin-related receptor, LDLR class A repeats-containing
Synonyms: Sorla, LR11, mSorLA, 2900010L19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20660
Homologene: 2336
Cd34
Name: CD34 antigen
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12490
HGNC: HGNC:1662
Homologene: 1343
Clec4a2
Name: C-type lectin domain family 4, member a2
Synonyms: Dcir1, Clecsf6, DCIR, dendritic cell immunoreceptor
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 26888
Homologene: 49291
Trp73
Name: transformation related protein 73
Synonyms: deltaNp73, TAp73, p73
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 22062
Homologene: 3960
Adgrf5
Name: adhesion G protein-coupled receptor F5
Synonyms: 8430401C09Rik, Gpr116
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224792
VEGA: 17
Homologene: 9065
Ttn
Name: titin
Synonyms: shru, L56, mdm, connectin, D330041I19Rik, 2310057K23Rik, 2310074I15Rik, 2310036G12Rik, D830007G01Rik, 1100001C23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Tet3
Name: tet methylcytosine dioxygenase 3
Synonyms: B430006D22Rik, D230004J03Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 194388
Homologene: 35360
Fat3
Name: FAT atypical cadherin 3
Synonyms: D430038H04Rik, LOC234973, LOC382129, 9430076A06Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270120
VEGA: 9
Homologene: 82252
Or51a6
Name: olfactory receptor family 51 subfamily A member 6
Synonyms: GA_x6K02T2PBJ9-5666843-5665908, Olfr575, MOR8-1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259118
Homologene: 122786
Ltbp1
Name: latent transforming growth factor beta binding protein 1
Synonyms: 9430031G15Rik, LTBP-1, b2b1000Clo, Ltbp1L
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268977
HGNC: HGNC:6714
Homologene: 522
Def6
Name: differentially expressed in FDCP 6
Synonyms: IBP, 2410003F05Rik, IRF-4-binding protein, 6430538D02Rik, SLAT
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 23853
HGNC: HGNC:2760
Homologene: 11103
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239420
Homologene: 65982
Cacna1b
Name: calcium channel, voltage-dependent, N type, alpha 1B subunit
Synonyms: Cchn1a, alpha(1B), Cav2.2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12287
HGNC: HGNC:1389
Homologene: 20184
Myo3b
Name: myosin IIIB
Synonyms: A430065P19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 329421
Homologene: 51393
Spag16
Name: sperm associated antigen 16
Synonyms: 4921511D23Rik, 4930585K05Rik, 4930524F24Rik, Pf20, Wdr29
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66722
Homologene: 11572
Frem3
Name: Fras1 related extracellular matrix protein 3
Synonyms: LOC333315
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 333315
Homologene: 35388
Hnf4g
Name: hepatocyte nuclear factor 4, gamma
Synonyms: NR2A2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 30942
HGNC: HGNC:5026
Homologene: 37886
Apoh
Name: apolipoprotein H
Synonyms: beta-2-glycoprotein 1, beta-2-GPI, B2GPI
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11818
HGNC: HGNC:616
Homologene: 26
Sec14l3
Name: SEC14-like lipid binding 3
Synonyms: 1110069O07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380683
Homologene: 24848
Spice1
Name: spindle and centriole associated protein 1
Synonyms: Ccdc52, D16Ertd480e
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 212514
Homologene: 16931
0610040J01Rik
Name: RIKEN cDNA 0610040J01 gene
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 76261
Homologene: 49537
Adat2
Name: adenosine deaminase, tRNA-specific 2
Synonyms: Deadc1, 4933426M09Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66757
Homologene: 6262
Klhl35
Name: kelch-like 35
Synonyms: 2810406K13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 72184
Homologene: 27849
Pramel14
Name: PRAME like 14
Synonyms: Pramef17, Gm13107
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 626943
Homologene: 129642
Ccdc188
Name: coiled-coil domain containing 188
Synonyms: Gm7873
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 102638083
VEGA: 16
Homologene: 90442
Vmn2r4
Name: vomeronasal 2, receptor 4
Synonyms: EG637053
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 637053
Homologene: 129754
Fam13a
Name: family with sequence similarity 13, member A
Synonyms: D430015B01Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 58909
Homologene: 135847
Slc19a3
Name: solute carrier family 19, member 3
Synonyms: ThTr2, A230084E24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 80721
Homologene: 23530
Klhl40
Name: kelch-like 40
Synonyms: 2310024D23Rik, Kbtbd5
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 72330
VEGA: 9
Homologene: 17571
Snph
Name: syntaphilin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241727
Homologene: 8817
Zscan4d
Name: zinc finger and SCAN domain containing 4D
Synonyms: EG545913
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 545913
Homologene: 85986
Bcl2l12
Name: BCL2 like 12
Synonyms: Bcl-L12, Bcl2-L12, 2810475P17Rik, 5430429M05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 75736
Homologene: 12619
Ska1
Name: spindle and kinetochore associated complex subunit 1
Synonyms: 2810433K01Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 66468
VEGA: 18
Homologene: 11975
Wdr81
Name: WD repeat domain 81
Synonyms: MGC32441, shakey 5, nur5
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192652
Homologene: 13983
Mapk7
Name: mitogen-activated protein kinase 7
Synonyms: big MAP kinase 1, b2b2346Clo, Erk5-T, BMK1, ERK5
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 23939
HGNC: HGNC:6880
Homologene: 2060
Rfxank
Name: regulatory factor X-associated ankyrin-containing protein
Synonyms: Tvl1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 19727
HGNC: HGNC:9987
Homologene: 2760
Gm3404
Name: predicted gene 3404
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100041554
Homologene: 86127
Trav5-4
Name: T cell receptor alpha variable 5-4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 21507
Ighv13-2
Name: immunoglobulin heavy variable 13-2
Synonyms: Gm15449
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 629842
HGNC: HGNC:5623
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • C to A, chromosome 1 at 69,844,336 bp (GRCm38)
  • T to C, chromosome 1 at 83,022,576 bp (GRCm38)
  • T to A, chromosome 1 at 194,959,193 bp (GRCm38)
  • T to C, chromosome 2 at 24,706,270 bp (GRCm38)
  • A to G, chromosome 2 at 70,256,564 bp (GRCm38)
  • A to G, chromosome 2 at 76,948,015 bp (GRCm38)
  • A to T, chromosome 2 at 119,070,608 bp (GRCm38)
  • T to C, chromosome 2 at 151,594,411 bp (GRCm38)
  • T to G, chromosome 3 at 3,638,213 bp (GRCm38)
  • T to C, chromosome 3 at 64,409,850 bp (GRCm38)
  • T to C, chromosome 4 at 101,177,729 bp (GRCm38)
  • A to C, chromosome 4 at 143,993,117 bp (GRCm38)
  • G to A, chromosome 4 at 154,063,946 bp (GRCm38)
  • A to G, chromosome 5 at 14,162,203 bp (GRCm38)
  • T to A, chromosome 5 at 63,898,605 bp (GRCm38)
  • A to G, chromosome 5 at 104,489,390 bp (GRCm38)
  • T to C, chromosome 5 at 146,526,221 bp (GRCm38)
  • A to G, chromosome 6 at 58,974,029 bp (GRCm38)
  • C to A, chromosome 6 at 83,404,154 bp (GRCm38)
  • A to T, chromosome 6 at 123,124,983 bp (GRCm38)
  • A to T, chromosome 7 at 11,165,018 bp (GRCm38)
  • G to T, chromosome 7 at 44,992,877 bp (GRCm38)
  • C to G, chromosome 7 at 99,468,495 bp (GRCm38)
  • A to T, chromosome 7 at 102,955,426 bp (GRCm38)
  • T to C, chromosome 8 at 70,135,548 bp (GRCm38)
  • C to A, chromosome 8 at 80,612,505 bp (GRCm38)
  • G to A, chromosome 9 at 16,375,575 bp (GRCm38)
  • A to T, chromosome 9 at 42,031,781 bp (GRCm38)
  • T to A, chromosome 9 at 121,778,677 bp (GRCm38)
  • T to A, chromosome 10 at 13,562,708 bp (GRCm38)
  • T to C, chromosome 10 at 80,784,779 bp (GRCm38)
  • G to A, chromosome 11 at 4,075,486 bp (GRCm38)
  • T to C, chromosome 11 at 61,491,672 bp (GRCm38)
  • T to C, chromosome 11 at 75,454,363 bp (GRCm38)
  • T to C, chromosome 11 at 94,569,976 bp (GRCm38)
  • G to A, chromosome 11 at 108,395,966 bp (GRCm38)
  • T to C, chromosome 12 at 87,246,211 bp (GRCm38)
  • T to C, chromosome 12 at 114,358,176 bp (GRCm38)
  • A to G, chromosome 14 at 53,704,359 bp (GRCm38)
  • G to T, chromosome 15 at 47,981,903 bp (GRCm38)
  • A to T, chromosome 16 at 18,218,404 bp (GRCm38)
  • C to T, chromosome 16 at 44,379,308 bp (GRCm38)
  • A to G, chromosome 17 at 28,219,781 bp (GRCm38)
  • T to A, chromosome 17 at 34,033,046 bp (GRCm38)
  • G to T, chromosome 17 at 43,449,904 bp (GRCm38)
  • A to G, chromosome 17 at 75,296,222 bp (GRCm38)
  • A to T, chromosome 18 at 74,199,939 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9671 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069464-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.