Strain Name:
C57BL/6J-MtgxR9685Btlr/Mmmh
Stock Number:
069478-MU
Citation ID:
RRID:MMRRC_069478-MU
Other Names:
R9685 (G1)
Major Collection:

Strain Information

Dnajc3
Name: DnaJ heat shock protein family (Hsp40) member C3
Synonyms: Prkri, Dnajc3, p58IPK, Dnajc3a, mp58, Dnajc3b
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 100037258
VEGA: 14
HGNC: HGNC:9439
Homologene: 2486
Grm1
Name: glutamate receptor, metabotropic 1
Synonyms: mGluR1, rcw, Grm1, Gprc1a, nmf373, 4930455H15Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 14816
HGNC: HGNC:4593
Homologene: 649
Scarb1
Name: scavenger receptor class B, member 1
Synonyms: Cla-1, D5Ertd460e, Hdlq1, Chohd1, Hlb398, SRBI, Srb1, Cd36l1, Chohd1, SR-BI
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20778
HGNC: HGNC:1664
Homologene: 21132
Fryl
Name: FRY like transcription coactivator
Synonyms: 2310004H21Rik, 9030227G01Rik, 2510002A14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72313
Homologene: 103956
Cdk13
Name: cyclin dependent kinase 13
Synonyms: Cdc2l5, 2310015O17Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 69562
VEGA: 13
HGNC: HGNC:1733
Homologene: 135707
Dcaf1
Name: DDB1 and CUL4 associated factor 1
Synonyms: Vprbp, B930007L02Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 321006
Homologene: 8805
Elovl5
Name: ELOVL fatty acid elongase 5
Synonyms: 1110059L23Rik, ELOVL family member 5, elongation of long chain fatty acids (yeast)
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 68801
Homologene: 41449
Scaper
Name: S phase cyclin A-associated protein in the ER
Synonyms: D530014O03Rik, Zfp291
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244891
VEGA: 9
Homologene: 32488
Rsf1
Name: remodeling and spacing factor 1
Synonyms: Hbxap, p325, XAP8, C030033M12Rik, 4832420A03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233532
Homologene: 41142
Hip1
Name: huntingtin interacting protein 1
Synonyms: E130315I21Rik, HIP-1, 2610109B09Rik, A930014B11Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 215114
HGNC: HGNC:4913
Homologene: 68463
Irak4
Name: interleukin-1 receptor-associated kinase 4
Synonyms: 9330209D03Rik, NY-REN-64, IRAK-4, 8430405M07Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 266632
Homologene: 41109
Snapc1
Name: small nuclear RNA activating complex, polypeptide 1
Synonyms: 9630050P21Rik, 2700033G17Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 75627
VEGA: 12
Homologene: 2317
Rtca
Name: RNA 3'-terminal phosphate cyclase
Synonyms: Rtcd1, 2310009A18Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 66368
Homologene: 2766
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: LOC381562, A930005E13Rik, D930005K06Rik, Zubr1, p600, 1810009A16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69116
Homologene: 10804
Cspp1
Name: centrosome and spindle pole associated protein 1
Synonyms: 4930413O22Rik, 2310020J12Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 211660
Homologene: 23487
Jup
Name: junction plakoglobin
Synonyms: D930025P04Rik, Ctnng, PG, plakoglobin, gamma-catenin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16480
HGNC: HGNC:6207
Homologene: 1680
Hhip
Name: Hedgehog-interacting protein
Synonyms: Hhip1, Hip, Hip1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 15245
Homologene: 32469
Lrrn4cl
Name: LRRN4 C-terminal like
Synonyms: 1110067I12Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 68852
VEGA: 19
Homologene: 45730
Bcl2a1a
Name: B cell leukemia/lymphoma 2 related protein A1a
Synonyms: Hbpa1, Bcl2a1, A1, Bfl-1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12044
HGNC: HGNC:991
Homologene: 2988
Spta1
Name: spectrin alpha, erythrocytic 1
Synonyms: Spna1, ihj, erythroid, Spna-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20739
Homologene: 74460
Vmn2r6
Name: vomeronasal 2, receptor 6
Synonyms: EG667069, EG620718
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 667069
Homologene: 129754
Vmn2r15
Name: vomeronasal 2, receptor 15
Synonyms: EG211223
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 211223
Homologene: 129606
Arhgef5
Name: Rho guanine nucleotide exchange factor 5
Synonyms: 2210412D05Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 54324
Homologene: 66300
Cspg4
Name: chondroitin sulfate proteoglycan 4
Synonyms: Cspg4a, AN2, 4732461B14Rik, NG2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 121021
VEGA: 9
HGNC: HGNC:2466
Homologene: 20445
Synpo2
Name: synaptopodin 2
Synonyms: 1110069I04Rik, 9530006G20Rik, Myo, myopodin, 2310068J10Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 118449
Homologene: 15400
Mapkbp1
Name: mitogen-activated protein kinase binding protein 1
Synonyms: 2810483F24Rik, Jnkbp1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 26390
Homologene: 69109
Impa1
Name: inositol (myo)-1(or 4)-monophosphatase 1
Synonyms: 2900059K10Rik, lithium-sensitive myo-inositol monophosphatase A1, 2610002K09Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 55980
HGNC: HGNC:6050
Homologene: 4043
Ddx28
Name: DEAD box helicase 28
Synonyms: 2410004K13Rik, Mddx28, DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71986
Homologene: 10164
Rrs1
Name: ribosome biogenesis regulator 1
Synonyms: 5730466A07Rik, D1Ertd701e
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 59014
Homologene: 41014
Krtap12-21
Name: keratin associated protein 12-21
Synonyms: Gm10142
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 100502921
VEGA: 10
Homologene: 135713
Pramel14
Name: PRAME like 14
Synonyms: Pramef17, Gm13107
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 626943
Homologene: 129642
Zfyve16
Name: zinc finger, FYVE domain containing 16
Synonyms: B130024H06Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218441
Homologene: 8826
Cnot6l
Name: CCR4-NOT transcription complex, subunit 6-like
Synonyms: 4932442K20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231464
Homologene: 100830
Dsc1
Name: desmocollin 1
Synonyms: Dsc1b, Dsc1a
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13505
VEGA: 18
HGNC: HGNC:3035
Homologene: 22761
Or8k16
Name: olfactory receptor family 8 subfamily K member 16
Synonyms: GA_x6K02T2Q125-47170431-47171372, MOR187-3, Olfr1008
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258866
Cd163
Name: CD163 antigen
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 93671
HGNC: HGNC:1631
Homologene: 128811
4930453N24Rik
Name: RIKEN cDNA 4930453N24 gene
Synonyms: din
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 67609
Homologene: 27867
Rasa4
Name: RAS p21 protein activator 4
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 54153
Homologene: 5080
Acp4
Name: acid phosphatase 4
Synonyms: EG546967, Acpt
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100503991
Homologene: 57200
Aanat
Name: arylalkylamine N-acetyltransferase
Synonyms: Nat-2, SNAT, Nat4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11298
HGNC: HGNC:19
Homologene: 31013
Clrn2
Name: clarin 2
Synonyms: mpc169H, EG624224
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 624224
Homologene: 84057
Vmn1r18
Name: vomeronasal 1 receptor 18
Synonyms: V1rc26
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171199
Homologene: 138094
A130010J15Rik
Name: RIKEN cDNA A130010J15 gene
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 319266
Homologene: 17592
Speer4a3
Name: spermatogenesis associated glutamate (E)-rich protein 4A3
Synonyms: Gm21671
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100862359
Homologene: 69402
Fam25a
Name: family with sequence similarity 25, member A
Synonyms: 2200001I15Rik, Fam25c
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 69134
Homologene: 129934
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 9,546,165 bp (GRCm38)
  • C to T, chromosome 1 at 10,126,414 bp (GRCm38)
  • T to C, chromosome 1 at 174,205,359 bp (GRCm38)
  • G to A, chromosome 1 at 193,174,757 bp (GRCm38)
  • T to C, chromosome 2 at 85,689,522 bp (GRCm38)
  • C to A, chromosome 2 at 120,021,183 bp (GRCm38)
  • T to A, chromosome 3 at 10,328,370 bp (GRCm38)
  • A to G, chromosome 3 at 64,556,660 bp (GRCm38)
  • T to A, chromosome 3 at 116,499,576 bp (GRCm38)
  • T to C, chromosome 3 at 123,117,717 bp (GRCm38)
  • A to G, chromosome 4 at 139,464,030 bp (GRCm38)
  • T to A, chromosome 4 at 143,992,950 bp (GRCm38)
  • AACT to A, chromosome 5 at 25,950,851 bp (GRCm38)
  • A to G, chromosome 5 at 45,453,989 bp (GRCm38)
  • T to C, chromosome 5 at 73,059,536 bp (GRCm38)
  • A to G, chromosome 5 at 96,082,890 bp (GRCm38)
  • A to G, chromosome 5 at 109,292,732 bp (GRCm38)
  • A to T, chromosome 5 at 125,294,130 bp (GRCm38)
  • A to G, chromosome 5 at 135,449,822 bp (GRCm38)
  • A to G, chromosome 5 at 136,095,529 bp (GRCm38)
  • T to G, chromosome 6 at 43,273,593 bp (GRCm38)
  • T to C, chromosome 6 at 57,390,478 bp (GRCm38)
  • T to C, chromosome 6 at 124,311,425 bp (GRCm38)
  • G to A, chromosome 7 at 44,257,309 bp (GRCm38)
  • CGGC to CGGCGGCGGGGGC, chromosome 7 at 97,579,932 bp (GRCm38)
  • A to T, chromosome 8 at 79,996,734 bp (GRCm38)
  • T to C, chromosome 8 at 106,010,101 bp (GRCm38)
  • A to T, chromosome 9 at 55,864,551 bp (GRCm38)
  • T to G, chromosome 9 at 56,890,338 bp (GRCm38)
  • T to C, chromosome 9 at 77,961,009 bp (GRCm38)
  • T to C, chromosome 9 at 88,957,132 bp (GRCm38)
  • C to T, chromosome 9 at 106,836,619 bp (GRCm38)
  • T to C, chromosome 10 at 10,689,031 bp (GRCm38)
  • A to G, chromosome 10 at 77,715,928 bp (GRCm38)
  • A to C, chromosome 11 at 100,383,411 bp (GRCm38)
  • A to C, chromosome 11 at 116,596,855 bp (GRCm38)
  • T to C, chromosome 12 at 73,970,341 bp (GRCm38)
  • C to A, chromosome 13 at 17,803,957 bp (GRCm38)
  • A to T, chromosome 13 at 92,522,803 bp (GRCm38)
  • G to A, chromosome 14 at 34,355,309 bp (GRCm38)
  • A to T, chromosome 14 at 118,972,363 bp (GRCm38)
  • T to A, chromosome 15 at 94,553,931 bp (GRCm38)
  • G to T, chromosome 16 at 64,766,460 bp (GRCm38)
  • G to A, chromosome 18 at 20,099,030 bp (GRCm38)
  • T to A, chromosome 19 at 8,852,055 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9685 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069478-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.