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Strain Name:
C57BL/6J-MtgxR9695Btlr/Mmmh
Stock Number:
069488-MU
Citation ID:
RRID:MMRRC_069488-MU
Other Names:
R9695 (G1)
Major Collection:

Strain Information

Otx2
Name: orthodenticle homeobox 2
Synonyms: E130306E05Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 18424
HGNC: HGNC:8522
Homologene: 11026
Neurog2
Name: neurogenin 2
Synonyms: Math4A, ngn2, Atoh4, bHLHa8
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11924
Homologene: 7633
Il4i1
Name: interleukin 4 induced 1
Synonyms: Fig1-ps, Fig1, H46, H4, H-46, H-4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14204
Homologene: 22567
Rictor
Name: RPTOR independent companion of MTOR, complex 2
Synonyms: 6030405M08Rik, D530039E11Rik, 4921505C17Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 78757
VEGA: 15
Homologene: 34317
Zmym6
Name: zinc finger, MYM-type 6
Synonyms: D4Wsu24e, 9330177P20Rik, Zfp258
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100177
Homologene: 5186
Dvl2
Name: dishevelled segment polarity protein 2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 13543
HGNC: HGNC:3086
Homologene: 20927
Heatr1
Name: HEAT repeat containing 1
Synonyms: B130016L12Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 217995
VEGA: 13
Homologene: 34562
Itpr1
Name: inositol 1,4,5-trisphosphate receptor 1
Synonyms: P400, IP3R1, Itpr-1, Ip3r, Pcp-1, opt, InsP3R type I, Pcp1, wblo
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16438
HGNC: HGNC:6180
Homologene: 1673
Syne1
Name: spectrin repeat containing, nuclear envelope 1
Synonyms: nesprin-1, SYNE-1, enaptin165, A330049M09Rik, C130039F11Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 64009
VEGA: 10
Homologene: 52329
Vars1
Name: valyl-tRNA synthetase 1
Synonyms: G7a, D17H6S56E, Bat-6, Bat6, Vars2, Vars
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22321
Homologene: 4587
Zfp160
Name: zinc finger protein 160
Synonyms: 6720480D16Rik, 6720480D16Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224585
VEGA: 17
Homologene: 137372
Adgrl1
Name: adhesion G protein-coupled receptor L1
Synonyms: Lec2, lectomedin-2, 2900070I05Rik, Lphn1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 330814
Homologene: 8951
Plxna4
Name: plexin A4
Synonyms: Plxa4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243743
HGNC: HGNC:9102
Homologene: 77587
Cbln4
Name: cerebellin 4 precursor protein
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228942
Homologene: 15419
Avpr1a
Name: arginine vasopressin receptor 1A
Synonyms: V1aR
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 54140
HGNC: HGNC:895
Homologene: 568
Mal
Name: myelin and lymphocyte protein, T cell differentiation protein
Synonyms: VIP17
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17153
HGNC: HGNC:6817
Homologene: 7827
Gna15
Name: guanine nucleotide binding protein, alpha 15
Synonyms: Galpha15, G[a]15
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 14676
HGNC: HGNC:4383
Homologene: 1563
Hspg2
Name: perlecan (heparan sulfate proteoglycan 2)
Synonyms: per, Pcn, Plc, perlecan
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 15530
HGNC: HGNC:5273
Homologene: 68473
Riok1
Name: RIO kinase 1
Synonyms: 5430416A05Rik, 3110046C13Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 71340
VEGA: 13
Homologene: 6950
Cwf19l1
Name: CWF19 like cell cycle control factor 1
Synonyms: 2610528C06Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 72502
VEGA: 19
Homologene: 41244
Rbm19
Name: RNA binding motif protein 19
Synonyms: 1200009A02Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 74111
Homologene: 7158
Nup160
Name: nucleoporin 160
Synonyms: 2810011M03Rik, Gtl1-13
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 59015
Homologene: 32509
Slmap
Name: sarcolemma associated protein
Synonyms: Slap, D330001L02Rik, Miranda
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 83997
Homologene: 31428
Slc15a4
Name: solute carrier family 15, member 4
Synonyms: C130069N12Rik, PTR4, PHT1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100561
Homologene: 26432
Prss35
Name: serine protease 35
Synonyms: 6030424L22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244954
Homologene: 17734
Apeh
Name: acylpeptide hydrolase
Synonyms: N-acylaminoacyl peptide hydrolase
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235606
HGNC: HGNC:586
Homologene: 1240
Tespa1
Name: thymocyte expressed, positive selection associated 1
Synonyms: A430001F24Rik, 5830405N20Rik, Itprid3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67596
VEGA: 10
Homologene: 106645
Slc9c1
Name: solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
Synonyms: LOC208169, spermNHE, Slc9a10
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 208169
Homologene: 19505
Dpysl3
Name: dihydropyrimidinase-like 3
Synonyms: Ulip1, Ulip, CRMP-4, TUC4, 9430041P20Rik, CRMP4
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 22240
HGNC: HGNC:3015
Homologene: 20361
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241516
Homologene: 110349
Snrk
Name: SNF related kinase
Synonyms: SNRK, 2010012F07Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20623
Homologene: 9797
Gstt4
Name: glutathione S-transferase, theta 4
Synonyms: 4930583C14Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 75886
Homologene: 57104
Slc44a5
Name: solute carrier family 44, member 5
Synonyms: LOC242259
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242259
Homologene: 72094
Stil
Name: Scl/Tal1 interrupting locus
Synonyms: Sil
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 20460
Homologene: 2283
Ifi206
Name: interferon activated gene 206
Synonyms: Gm4955, Pyblhin-C
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 102639543
HGNC: HGNC:5395
Homologene: 115929
Dsg1b
Name: desmoglein 1 beta
Synonyms: Dsg5
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225256
HGNC: HGNC:3048
Homologene: 1463
Ablim1
Name: actin-binding LIM protein 1
Synonyms: Limab1, 4833406P10Rik, abLIM-S, abLIM-M, abLIM-L, 2610209L21Rik, 9330196J19Rik, 2210411C18Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226251
HGNC: HGNC:78
Homologene: 40994
Cd96
Name: CD96 antigen
Synonyms: Tactile, 1700109I12Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 84544
Homologene: 68489
Map9
Name: microtubule-associated protein 9
Synonyms: 5033421J10Rik, 5330427D05Rik, ASAP, Mtap9
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213582
Homologene: 41591
Thumpd3
Name: THUMP domain containing 3
Synonyms: Gtrosa26as
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14911
Homologene: 7351
Mmp15
Name: matrix metallopeptidase 15
Synonyms: MT2-MMP, Membrane type 2-MMP
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17388
HGNC: HGNC:7161
Homologene: 20549
Hip1r
Name: huntingtin interacting protein 1 related
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 29816
Homologene: 78348
Vwa5b2
Name: von Willebrand factor A domain containing 5B2
Synonyms: EG328644
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 328643
Homologene: 28056
Armc12
Name: armadillo repeat containing 12
Synonyms: 4930511I11Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 67645
Homologene: 12168
Zfp759
Name: zinc finger protein 759
Synonyms: Rslcan-8
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 268670
VEGA: 13
Piwil2
Name: piwi-like RNA-mediated gene silencing 2
Synonyms: Miwi like, mili
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 57746
VEGA: 14
Homologene: 23071
Cel
Name: carboxyl ester lipase
Synonyms: BAL, 1810036E18Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12613
HGNC: HGNC:1848
Homologene: 37529
Ccdc89
Name: coiled-coil domain containing 89
Synonyms: 1700019B01Rik, BOIP
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 70054
Homologene: 17653
Or8k30
Name: olfactory receptor family 8 subfamily K member 30
Synonyms: GA_x6K02T2Q125-47993761-47994702, MOR189-2, Olfr1076
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258401
Homologene: 17233
Slco2a1
Name: solute carrier organic anion transporter family, member 2a1
Synonyms: Pgt, 2310021C19Rik, mPgt, Slc21a2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 24059
Homologene: 38077
Itga3
Name: integrin alpha 3
Synonyms: VLA-3 alpha 3, alpha3-integrin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16400
HGNC: HGNC:6139
Homologene: 21129
Or2a52
Name: olfactory receptor family 2 subfamily A member 52
Synonyms: GA_x6K02T2P3E9-4391088-4390156, MOR261-11, Olfr437
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258293
HGNC: HGNC:8230
Homologene: 122778
Nelfcd
Name: negative elongation factor complex member C/D, Th1l
Synonyms: 2410003I03Rik, trihydrophobin 1, Th1l
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 57314
Homologene: 9496
Fech
Name: ferrochelatase
Synonyms: fch, Fcl
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 14151
VEGA: 18
HGNC: HGNC:3647
Homologene: 113
Tcirg1
Name: T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
Synonyms: V-ATPase a3, OC-116, TIRC7, ATP6a3, Atp6i
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 27060
Homologene: 4392
Oosp2
Name: oocyte secreted protein 2
Synonyms: LOC225922, Tmem122, Plac1l
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225922
Homologene: 52157
Elovl7
Name: ELOVL fatty acid elongase 7
Synonyms: 9130013K24Rik, ELOVL family member 7, elongation of long chain fatty acids (yeast)
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 74559
VEGA: 13
Homologene: 23672
Oasl1
Name: 2'-5' oligoadenylate synthetase-like 1
Synonyms: 7530414C13Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231655
HGNC: HGNC:8090
Homologene: 2769
Or9s27
Name: olfactory receptor family 9 subfamily S member 27
Synonyms: GA_x6K02T2R7CC-81165686-81164721, MOR208-4, Olfr1412
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 258274
Homologene: 115514
Or7g22
Name: olfactory receptor family 7 subfamily G member 22
Synonyms: GA_x6K02T2PVTD-12873838-12874776, MOR152-2, Olfr837
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258558
HGNC: HGNC:8466
Homologene: 115507
Tmem70
Name: transmembrane protein 70
Synonyms: 2210416J16Rik, 1110020A09Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 70397
Homologene: 9890
Crtap
Name: cartilage associated protein
Synonyms: CASP, 5730529N23Rik, Leprel3, P3h5
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 56693
HGNC: HGNC:2379
Homologene: 21280
Ctxn3
Name: cortexin 3
Synonyms: ENSMUSG00000069372
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 629147
Homologene: 85473
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to C, chromosome 1 at 16,665,435 bp (GRCm38)
  • A to G, chromosome 1 at 92,588,873 bp (GRCm38)
  • T to C, chromosome 1 at 173,473,683 bp (GRCm38)
  • G to T, chromosome 2 at 28,560,949 bp (GRCm38)
  • A to T, chromosome 2 at 82,975,882 bp (GRCm38)
  • T to C, chromosome 2 at 86,508,756 bp (GRCm38)
  • T to A, chromosome 2 at 90,708,142 bp (GRCm38)
  • T to C, chromosome 2 at 91,162,584 bp (GRCm38)
  • C to T, chromosome 2 at 127,640,388 bp (GRCm38)
  • C to G, chromosome 2 at 172,037,549 bp (GRCm38)
  • T to A, chromosome 2 at 174,425,130 bp (GRCm38)
  • A to G, chromosome 3 at 55,126,534 bp (GRCm38)
  • T to A, chromosome 3 at 82,376,985 bp (GRCm38)
  • T to A, chromosome 3 at 127,634,045 bp (GRCm38)
  • T to A, chromosome 3 at 154,250,951 bp (GRCm38)
  • T to C, chromosome 4 at 115,024,181 bp (GRCm38)
  • T to C, chromosome 4 at 127,122,547 bp (GRCm38)
  • T to A, chromosome 4 at 137,538,390 bp (GRCm38)
  • G to A, chromosome 5 at 114,935,995 bp (GRCm38)
  • T to C, chromosome 5 at 120,197,921 bp (GRCm38)
  • A to T, chromosome 5 at 124,001,853 bp (GRCm38)
  • G to A, chromosome 5 at 127,617,336 bp (GRCm38)
  • T to G, chromosome 6 at 32,206,121 bp (GRCm38)
  • A to T, chromosome 6 at 43,167,576 bp (GRCm38)
  • A to G, chromosome 6 at 108,401,350 bp (GRCm38)
  • G to T, chromosome 6 at 113,047,661 bp (GRCm38)
  • A to T, chromosome 7 at 44,839,609 bp (GRCm38)
  • A to G, chromosome 7 at 90,427,344 bp (GRCm38)
  • G to A, chromosome 8 at 83,938,431 bp (GRCm38)
  • G to T, chromosome 8 at 95,370,786 bp (GRCm38)
  • A to G, chromosome 9 at 19,137,875 bp (GRCm38)
  • A to G, chromosome 9 at 86,755,708 bp (GRCm38)
  • A to G, chromosome 9 at 103,084,940 bp (GRCm38)
  • G to A, chromosome 9 at 108,086,284 bp (GRCm38)
  • A to T, chromosome 9 at 114,386,310 bp (GRCm38)
  • T to C, chromosome 9 at 122,166,574 bp (GRCm38)
  • A to G, chromosome 10 at 5,318,461 bp (GRCm38)
  • A to G, chromosome 10 at 13,474,164 bp (GRCm38)
  • A to T, chromosome 10 at 75,821,238 bp (GRCm38)
  • A to G, chromosome 10 at 81,523,918 bp (GRCm38)
  • C to T, chromosome 10 at 122,448,940 bp (GRCm38)
  • T to C, chromosome 10 at 130,362,416 bp (GRCm38)
  • G to A, chromosome 11 at 70,009,150 bp (GRCm38)
  • A to T, chromosome 11 at 95,055,694 bp (GRCm38)
  • T to C, chromosome 12 at 115,623,367 bp (GRCm38)
  • T to C, chromosome 13 at 12,423,743 bp (GRCm38)
  • A to G, chromosome 13 at 38,058,700 bp (GRCm38)
  • G to A, chromosome 13 at 67,139,134 bp (GRCm38)
  • C to A, chromosome 13 at 108,279,708 bp (GRCm38)
  • T to A, chromosome 14 at 26,462,341 bp (GRCm38)
  • T to G, chromosome 14 at 48,662,495 bp (GRCm38)
  • A to G, chromosome 14 at 70,389,900 bp (GRCm38)
  • T to G, chromosome 15 at 6,786,529 bp (GRCm38)
  • A to T, chromosome 16 at 20,604,225 bp (GRCm38)
  • T to C, chromosome 16 at 45,547,663 bp (GRCm38)
  • T to A, chromosome 16 at 46,099,047 bp (GRCm38)
  • A to G, chromosome 17 at 21,025,484 bp (GRCm38)
  • T to A, chromosome 17 at 28,531,019 bp (GRCm38)
  • A to G, chromosome 17 at 35,012,588 bp (GRCm38)
  • A to G, chromosome 18 at 20,399,332 bp (GRCm38)
  • A to T, chromosome 18 at 43,438,127 bp (GRCm38)
  • A to G, chromosome 18 at 57,477,113 bp (GRCm38)
  • A to G, chromosome 18 at 64,467,732 bp (GRCm38)
  • G to A, chromosome 19 at 3,902,360 bp (GRCm38)
  • T to C, chromosome 19 at 11,651,630 bp (GRCm38)
  • G to T, chromosome 19 at 44,112,986 bp (GRCm38)
  • T to C, chromosome 19 at 57,182,307 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9695 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069488-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.