Strain Name:
C57BL/6J-MtgxR9702Btlr/Mmmh
Stock Number:
069495-MU
Citation ID:
RRID:MMRRC_069495-MU
Other Names:
R9702 (G1)
Major Collection:

Strain Information

Bdnf
Name: brain derived neurotrophic factor
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12064
HGNC: HGNC:1033
Homologene: 7245
Sema3c
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
Synonyms: 1110036B02Rik, Semae
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20348
Homologene: 36201
Gtf2i
Name: general transcription factor II I
Synonyms: 6030441I21Rik, TFII-I, BAP-135
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14886
HGNC: HGNC:4659
Homologene: 7748
Gas2l3
Name: growth arrest-specific 2 like 3
Synonyms: LOC237436, 8430435B07Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237436
VEGA: 10
Homologene: 18386
Tox
Name: thymocyte selection-associated high mobility group box
Synonyms: 1700007F02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 252838
Homologene: 8822
Vps8
Name: VPS8 CORVET complex subunit
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 209018
Homologene: 44592
Apob
Name: apolipoprotein B
Synonyms: apob-48, apob-100
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Crim1
Name: cysteine rich transmembrane BMP regulator 1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 50766
VEGA: 17
HGNC: HGNC:2359
Homologene: 9510
Ccdc187
Name: coiled-coil domain containing 187
Synonyms: 4932418E24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 329366
Homologene: 77630
Mfsd14b
Name: major facilitator superfamily domain containing 14B
Synonyms: Hiatl1, 5730414C17Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66631
Homologene: 64464
Inpp5f
Name: inositol polyphosphate-5-phosphatase F
Synonyms: SAC2, cI-27, 5830435P03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101490
Homologene: 8962
Gp1bb
Name: glycoprotein Ib, beta polypeptide
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 14724
VEGA: 16
HGNC: HGNC:4440
Homologene: 30972
Ldb3
Name: LIM domain binding 3
Synonyms: cypher, ZASP
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 24131
VEGA: 14
Homologene: 134626
Gm11992
Name: predicted gene 11992
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 626870
Homologene: 77951
Fbxo30
Name: F-box protein 30
Synonyms: 1700026A16Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71865
Homologene: 12959
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: Mgr1, VLGR1, Gpr98, Mass1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 110789
Homologene: 19815
Esyt1
Name: extended synaptotagmin-like protein 1
Synonyms: vp115, Fam62a, Mbc2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 23943
VEGA: 10
Homologene: 40794
Abca6
Name: ATP-binding cassette, sub-family A member 6
Synonyms: 6330565N06Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76184
HGNC: HGNC:36
Homologene: 71264
Sobp
Name: sine oculis binding protein
Synonyms: 5330439J01Rik, 2900009C16Rik, Jxc1, jc
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 109205
Homologene: 41216
Pign
Name: phosphatidylinositol glycan anchor biosynthesis, class N
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 27392
HGNC: HGNC:8967
Homologene: 6330
Slc28a2b
Name: solute carrier family 28 member 2b
Synonyms: Gm14085
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 381417
Kynu
Name: kynureninase
Synonyms: L-kynurenine hydrolase, 4432411A05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 70789
HGNC: HGNC:6469
Homologene: 2925
Zfp108
Name: zinc finger protein 108
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 54678
Homologene: 117959
Mrps23
Name: mitochondrial ribosomal protein S23
Synonyms: 2310047I09Rik, Rpms23, D11Bwg1153e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 64656
Homologene: 41101
Lrrc31
Name: leucine rich repeat containing 31
Synonyms: E230002P03Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 320352
Nlrp4c
Name: NLR family, pyrin domain containing 4C
Synonyms: Rnh2, Nalp-alpha, Nalp4c
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 83564
Homologene: 75315
Ankrd6
Name: ankyrin repeat domain 6
Synonyms: diversin
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 140577
Homologene: 8967
Dsc1
Name: desmocollin 1
Synonyms: Dsc1b, Dsc1a
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13505
VEGA: 18
HGNC: HGNC:3035
Homologene: 22761
Tigd3
Name: tigger transposable element derived 3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 332359
VEGA: 19
Homologene: 129795
Cfap161
Name: cilia and flagella associated protein 161
Synonyms: 1700026D08Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 75556
Homologene: 12605
Cd84
Name: CD84 antigen
Synonyms: A130013D22Rik, CDw84, SLAMF5
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12523
HGNC: HGNC:1704
Homologene: 48249
Gfra4
Name: glial cell line derived neurotrophic factor family receptor alpha 4
Synonyms: GFR alpha-4, G630015H18Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14588
Homologene: 10565
Or51f1e
Name: olfactory receptor family 51 subfamily F member 1E
Synonyms: GA_x6K02T2PBJ9-5809085-5810035, Olfr585, MOR14-4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259091
Homologene: 133721
Vmn1r158
Name: vomeronasal 1 receptor 158
Synonyms: Gm16455
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100043067
Homologene: 104166
Vwa1
Name: von Willebrand factor A domain containing 1
Synonyms: WARP, 4932416A11Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 246228
Homologene: 11270
Rab11b
Name: RAB11B, member RAS oncogene family
Synonyms: A730055L17Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19326
HGNC: HGNC:9761
Homologene: 68691
Cd164
Name: CD164 antigen
Synonyms: A24, MGC-24, A115
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 53599
HGNC: HGNC:1632
Homologene: 38129
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 105,557,487 bp (GRCm38)
  • T to C, chromosome 1 at 171,872,931 bp (GRCm38)
  • C to T, chromosome 2 at 26,282,210 bp (GRCm38)
  • T to A, chromosome 2 at 43,589,457 bp (GRCm38)
  • A to T, chromosome 2 at 109,723,772 bp (GRCm38)
  • T to A, chromosome 2 at 122,523,531 bp (GRCm38)
  • T to A, chromosome 2 at 131,042,619 bp (GRCm38)
  • A to G, chromosome 3 at 30,681,077 bp (GRCm38)
  • T to G, chromosome 4 at 6,697,418 bp (GRCm38)
  • C to T, chromosome 4 at 32,810,202 bp (GRCm38)
  • G to A, chromosome 4 at 155,772,879 bp (GRCm38)
  • T to C, chromosome 5 at 17,653,830 bp (GRCm38)
  • T to C, chromosome 5 at 134,246,561 bp (GRCm38)
  • T to A, chromosome 7 at 6,065,802 bp (GRCm38)
  • T to A, chromosome 7 at 22,790,640 bp (GRCm38)
  • C to T, chromosome 7 at 24,260,770 bp (GRCm38)
  • T to A, chromosome 7 at 83,793,444 bp (GRCm38)
  • T to C, chromosome 7 at 103,098,136 bp (GRCm38)
  • A to C, chromosome 7 at 128,676,791 bp (GRCm38)
  • G to T, chromosome 10 at 11,290,638 bp (GRCm38)
  • G to A, chromosome 10 at 41,528,822 bp (GRCm38)
  • T to C, chromosome 10 at 43,021,948 bp (GRCm38)
  • C to T, chromosome 10 at 89,414,081 bp (GRCm38)
  • G to A, chromosome 10 at 128,520,738 bp (GRCm38)
  • T to G, chromosome 11 at 9,056,568 bp (GRCm38)
  • C to T, chromosome 11 at 88,210,172 bp (GRCm38)
  • A to G, chromosome 11 at 110,216,552 bp (GRCm38)
  • G to T, chromosome 12 at 8,007,559 bp (GRCm38)
  • C to A, chromosome 13 at 65,073,600 bp (GRCm38)
  • T to A, chromosome 13 at 81,536,364 bp (GRCm38)
  • A to G, chromosome 14 at 34,577,133 bp (GRCm38)
  • A to T, chromosome 16 at 18,621,134 bp (GRCm38)
  • A to G, chromosome 16 at 21,644,133 bp (GRCm38)
  • C to A, chromosome 17 at 33,749,052 bp (GRCm38)
  • T to A, chromosome 17 at 78,374,087 bp (GRCm38)
  • A to G, chromosome 18 at 20,094,628 bp (GRCm38)
  • G to A, chromosome 19 at 5,892,808 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9702 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069495-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.