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Wang G, Guo X, Diangelo S, Thomas NJ, Floros J. Humanized SFTPA1 and SFTPA2 transgenic mice reveal functional divergence of SP-A1 and SP-A2: formation of tubular myelin in vivo requires both gene products. J Biol Chem. 2010 Apr 16;285(16):11998-2010. doi: 10.1074/jbc.M109.046243. Epub 2010 Jan 4. (Medline PMID: 20048345)
Depicolzuane L, Phelps DS, Floros J. Surfactant Protein-A Function: Knowledge Gained From SP-A Knockout Mice. Front Pediatr. 2022 Jan 7;9:799693. doi: 10.3389/fped.2021.799693. (Medline PMID: 35071140)
Floros J, Thorenoor N, Tsotakos N, Phelps DS. Human Surfactant Protein SP-A1 and SP-A2 Variants Differentially Affect the Alveolar Microenvironment, Surfactant Structure, Regulation and Function of the Alveolar Macrophage, and Animal and Human Survival Under Various Conditions. Front Immunol. 2021 Aug 17;12:681639. doi: 10.3389/fimmu.2021.681639. (Medline PMID: 34484180)
Cryo-recovered strains distributed by the MMRRC at JAX are shipped to the customer from the Pathogen & Opportunistic-Free Animal Room G200 - see https://www.jax.org/jax-mice-and-services/customer-support/customer-service/animal-health/health-status-reports.
Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.
Cryopreserved material may be available upon request, please inquire to csmmrrc@jax.org for more information.
Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.