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Strain Name:
C57BL/6J-MtgxR9707Btlr/Mmmh
Stock Number:
069954-MU
Citation ID:
RRID:MMRRC_069954-MU
Other Names:
R9707 (G1)
Major Collection:

Strain Information

Dst
Name: dystonin
Synonyms: bullous pemphigoid antigen 1, BPAG1-n, BPAG1, Bpag1, Bpag, ah, bullous pemphigoid antigen 1, athetoid, Macf2, 2310001O04Rik, nmf203, A830042E19Rik, nmf339
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Mbd4
Name: methyl-CpG binding domain protein 4
Synonyms: Med1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 17193
HGNC: HGNC:6919
Homologene: 2916
Epb41l2
Name: erythrocyte membrane protein band 4.1 like 2
Synonyms: NBL2, 4.1G, D10Ertd398e, Epb4.1l2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 13822
VEGA: 10
HGNC: HGNC:3379
Homologene: 37478
Mcm7
Name: minichromosome maintenance complex component 7
Synonyms: mCDC47, Mcmd7
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 17220
HGNC: HGNC:6950
Homologene: 4323
Ptpn12
Name: protein tyrosine phosphatase, non-receptor type 12
Synonyms: P19-PTP, PTP-PEST, PTP-P19
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19248
HGNC: HGNC:9645
Homologene: 37691
Neurl4
Name: neuralized E3 ubiquitin protein ligase 4
Synonyms: 0610025P10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216860
Homologene: 13029
Phf3
Name: PHD finger protein 3
Synonyms: 2310061N19Rik, AU020177
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 213109
HGNC: HGNC:8921
Homologene: 9040
Ambra1
Name: autophagy/beclin 1 regulator 1
Synonyms: 2310079H06Rik, D030051N19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228361
Homologene: 18204
Rbbp6
Name: retinoblastoma binding protein 6, ubiquitin ligase
Synonyms: 4933422O15Rik, C030034J04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19647
HGNC: HGNC:9889
Homologene: 136812
Msr1
Name: macrophage scavenger receptor 1
Synonyms: SR-AII, SR-AI, MSR-A, Scara1, Scvr, MRS-A
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 20288
HGNC: HGNC:7376
Homologene: 12822
Ecpas
Name: Ecm29 proteasome adaptor and scaffold
Synonyms: AI314180
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230249
Homologene: 6056
Zfp236
Name: zinc finger protein 236
Synonyms: LOC240456
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 329002
Homologene: 7198
Asxl3
Name: ASXL transcriptional regulator 3
Synonyms: LOC381127, D930044O18Rik, D430002O22Rik, C230079D11Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 211961
Homologene: 19371
Ighd
Name: immunoglobulin heavy constant delta
Synonyms: IgD
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 380797
HGNC: HGNC:5480
Spmip2
Name: sperm microtubule inner protein 2
Synonyms: Gm17359
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 100233207
Homologene: 105634
Lrp1
Name: low density lipoprotein receptor-related protein 1
Synonyms: CD91, A2mr, b2b1554Clo
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16971
HGNC: HGNC:6692
Homologene: 1744
Mmp9
Name: matrix metallopeptidase 9
Synonyms: gelatinase B, Gel B, MMP-9, B/MMP9, Clg4b, Gelatinase B
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17395
HGNC: HGNC:7176
Homologene: 3659
Or1e35
Name: olfactory receptor family 1 subfamily E member 35
Synonyms: GA_x6K02T2P1NL-4062605-4061667, MOR135-10, Olfr395
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 259007
Slc22a21
Name: solute carrier family 22 (organic cation transporter), member 21
Synonyms: Octn3, Slc22a9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 56517
Homologene: 137336
BC016579
Name: cDNA sequence, BC016579
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 212998
VEGA: 16
Homologene: 11622
Ccdc54
Name: coiled-coil domain containing 54
Synonyms: 1700007N18Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 69339
VEGA: 16
Homologene: 49871
Zfp329
Name: zinc finger protein 329
Synonyms: 2810439M05Rik, 4632409L22Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67230
Homologene: 23459
Vmn1r22
Name: vomeronasal 1 receptor 22
Synonyms: V1rc23
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171196
Homologene: 110825
Ildr1
Name: immunoglobulin-like domain containing receptor 1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 106347
Homologene: 15892
Synj1
Name: synaptojanin 1
Synonyms: A930006D20Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 104015
Homologene: 48252
Smg9
Name: SMG9 nonsense mediated mRNA decay factor
Synonyms: N28092, 1500002O20Rik, smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans)
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71997
Homologene: 10426
Dohh
Name: deoxyhypusine hydroxylase/monooxygenase
Synonyms: 1110033C18Rik, Hlrc1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 102115
Homologene: 6290
Foxc1
Name: forkhead box C1
Synonyms: frkhda, fkh1, fkh-1, FREAC3, Mf1, Fkh1, Mf4
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17300
HGNC: HGNC:3800
Homologene: 20373
Usp16
Name: ubiquitin specific peptidase 16
Synonyms: 2810483I07Rik, UBP-M, 1200004E02Rik, 6330514E22Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74112
Homologene: 38183
Pde4c
Name: phosphodiesterase 4C, cAMP specific
Synonyms: dunce, Dpde1, E130301F19Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 110385
HGNC: HGNC:8782
Homologene: 20256
Cts3
Name: cathepsin 3
Synonyms: 1600000I23Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 117066
VEGA: 13
Or8s5
Name: olfactory receptor family 8 subfamily S member 5
Synonyms: GA_x6K02T2NBG7-5395976-5396893, MOR160-4, Olfr284
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 258278
Homologene: 74250
Arsj
Name: arylsulfatase J
Synonyms: 9330196J05Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 271970
Homologene: 35257
Or6c69b
Name: olfactory receptor family 6 subfamily C member 69B
Synonyms: GA_x6K02T2PULF-11470271-11469333, MOR113-4, Olfr810
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258543
Homologene: 46347
Amz1
Name: archaelysin family metallopeptidase 1
Synonyms: 6530401C20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231842
Homologene: 18290
Chac2
Name: ChaC, cation transport regulator 2
Synonyms: 2510006C20Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 68044
Homologene: 48696
Slc46a3
Name: solute carrier family 46, member 3
Synonyms: 1200006F02Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71706
Homologene: 41733
Taf7
Name: TATA-box binding protein associated factor 7
Synonyms: TAFII55, Taf2f, 55kDa
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 24074
Homologene: 133942
Pcdhgb6
Name: protocadherin gamma subfamily B, 6
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93703
HGNC: HGNC:8713
Homologene: 49573
Trav7-3
Name: T cell receptor alpha variable 7-3
Synonyms: Gm13946
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 547420
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • C to A, chromosome 1 at 30,829,842 bp (GRCm38)
  • T to C, chromosome 1 at 34,189,853 bp (GRCm38)
  • A to G, chromosome 1 at 75,360,889 bp (GRCm38)
  • G to A, chromosome 2 at 91,810,131 bp (GRCm38)
  • T to A, chromosome 2 at 164,952,685 bp (GRCm38)
  • A to G, chromosome 3 at 79,405,860 bp (GRCm38)
  • T to C, chromosome 3 at 126,438,511 bp (GRCm38)
  • C to T, chromosome 4 at 58,824,816 bp (GRCm38)
  • T to A, chromosome 5 at 21,002,622 bp (GRCm38)
  • C to A, chromosome 5 at 138,171,738 bp (GRCm38)
  • T to C, chromosome 5 at 140,748,194 bp (GRCm38)
  • G to T, chromosome 5 at 147,884,212 bp (GRCm38)
  • A to T, chromosome 6 at 57,900,905 bp (GRCm38)
  • T to A, chromosome 6 at 115,849,598 bp (GRCm38)
  • T to C, chromosome 7 at 12,810,202 bp (GRCm38)
  • G to T, chromosome 7 at 24,403,444 bp (GRCm38)
  • A to T, chromosome 7 at 122,989,838 bp (GRCm38)
  • T to G, chromosome 8 at 39,623,947 bp (GRCm38)
  • A to G, chromosome 8 at 70,750,052 bp (GRCm38)
  • G to A, chromosome 10 at 25,502,337 bp (GRCm38)
  • T to C, chromosome 10 at 81,387,731 bp (GRCm38)
  • T to C, chromosome 10 at 127,572,545 bp (GRCm38)
  • T to C, chromosome 10 at 129,791,575 bp (GRCm38)
  • T to C, chromosome 11 at 30,979,572 bp (GRCm38)
  • T to C, chromosome 11 at 53,960,360 bp (GRCm38)
  • A to T, chromosome 11 at 69,908,853 bp (GRCm38)
  • A to G, chromosome 11 at 73,907,264 bp (GRCm38)
  • T to A, chromosome 12 at 113,414,488 bp (GRCm38)
  • A to T, chromosome 12 at 115,158,415 bp (GRCm38)
  • A to T, chromosome 13 at 31,807,899 bp (GRCm38)
  • T to A, chromosome 13 at 61,566,835 bp (GRCm38)
  • A to G, chromosome 14 at 53,443,732 bp (GRCm38)
  • C to T, chromosome 15 at 98,340,273 bp (GRCm38)
  • T to G, chromosome 15 at 101,930,761 bp (GRCm38)
  • A to G, chromosome 16 at 36,709,530 bp (GRCm38)
  • C to T, chromosome 16 at 45,640,397 bp (GRCm38)
  • T to A, chromosome 16 at 50,590,800 bp (GRCm38)
  • T to C, chromosome 16 at 87,466,347 bp (GRCm38)
  • A to G, chromosome 16 at 90,961,412 bp (GRCm38)
  • A to G, chromosome 18 at 22,523,247 bp (GRCm38)
  • A to T, chromosome 18 at 37,643,000 bp (GRCm38)
  • T to C, chromosome 18 at 37,743,715 bp (GRCm38)
  • A to G, chromosome 18 at 82,646,203 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9707 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069954-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.