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Strain Name:
C57BL/6J-MtgxR9711Btlr/Mmmh
Stock Number:
069958-MU
Citation ID:
RRID:MMRRC_069958-MU
Other Names:
R9711 (G1)
Major Collection:

Strain Information

Rpl13a
Name: ribosomal protein L13A
Synonyms: tum-antigen, tum-transplantation antigen P198, Tstap198-7, 1810026N22Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22121
Homologene: 111053
Setd5
Name: SET domain containing 5
Synonyms: 2900045N06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 72895
Homologene: 12485
Slc1a3
Name: solute carrier family 1 (glial high affinity glutamate transporter), member 3
Synonyms: MGluT1, Eaat1, B430115D02Rik, GLAST, Gmt1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20512
Homologene: 20882
Rnf145
Name: ring finger protein 145
Synonyms: 3732413I11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74315
Homologene: 14427
Cdkn1b
Name: cyclin dependent kinase inhibitor 1B
Synonyms: p27Kip1, p27
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12576
HGNC: HGNC:1785
Homologene: 2999
Kdm5a
Name: lysine demethylase 5A
Synonyms: RBP2, Rbbp2, Jarid1a
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 214899
HGNC: HGNC:9886
Homologene: 3419
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 2 at 27,269,015 bp (GRCm38)
  • T to A, chromosome 2 at 60,229,831 bp (GRCm38)
  • T to A, chromosome 2 at 94,421,467 bp (GRCm38)
  • C to T, chromosome 2 at 102,400,468 bp (GRCm38)
  • A to T, chromosome 2 at 110,268,236 bp (GRCm38)
  • T to A, chromosome 2 at 150,408,287 bp (GRCm38)
  • T to A, chromosome 2 at 174,299,599 bp (GRCm38)
  • T to C, chromosome 3 at 33,082,055 bp (GRCm38)
  • C to T, chromosome 3 at 36,638,564 bp (GRCm38)
  • T to C, chromosome 3 at 39,001,225 bp (GRCm38)
  • T to A, chromosome 3 at 63,707,755 bp (GRCm38)
  • A to T, chromosome 3 at 142,242,768 bp (GRCm38)
  • T to A, chromosome 4 at 63,165,889 bp (GRCm38)
  • T to A, chromosome 4 at 101,735,654 bp (GRCm38)
  • A to G, chromosome 4 at 141,695,423 bp (GRCm38)
  • A to G, chromosome 4 at 144,395,947 bp (GRCm38)
  • C to T, chromosome 4 at 145,293,098 bp (GRCm38)
  • T to A, chromosome 4 at 146,466,888 bp (GRCm38)
  • G to A, chromosome 4 at 152,538,977 bp (GRCm38)
  • A to G, chromosome 5 at 35,984,196 bp (GRCm38)
  • A to G, chromosome 5 at 87,254,673 bp (GRCm38)
  • T to C, chromosome 5 at 92,434,359 bp (GRCm38)
  • T to C, chromosome 5 at 110,342,522 bp (GRCm38)
  • T to C, chromosome 5 at 127,792,515 bp (GRCm38)
  • T to A, chromosome 5 at 147,024,566 bp (GRCm38)
  • A to G, chromosome 6 at 33,476,056 bp (GRCm38)
  • C to T, chromosome 6 at 52,727,230 bp (GRCm38)
  • T to G, chromosome 6 at 55,887,033 bp (GRCm38)
  • T to C, chromosome 6 at 57,515,735 bp (GRCm38)
  • A to T, chromosome 6 at 57,955,819 bp (GRCm38)
  • T to A, chromosome 6 at 86,668,572 bp (GRCm38)
  • T to C, chromosome 6 at 113,116,102 bp (GRCm38)
  • T to A, chromosome 6 at 120,390,697 bp (GRCm38)
  • T to A, chromosome 6 at 127,965,752 bp (GRCm38)
  • A to G, chromosome 6 at 134,921,095 bp (GRCm38)
  • G to A, chromosome 7 at 7,384,086 bp (GRCm38)
  • C to A, chromosome 7 at 28,093,575 bp (GRCm38)
  • A to G, chromosome 7 at 45,127,249 bp (GRCm38)
  • A to T, chromosome 7 at 75,206,490 bp (GRCm38)
  • A to C, chromosome 7 at 113,788,448 bp (GRCm38)
  • A to G, chromosome 7 at 126,113,701 bp (GRCm38)
  • A to T, chromosome 7 at 126,547,502 bp (GRCm38)
  • T to A, chromosome 7 at 140,538,584 bp (GRCm38)
  • T to C, chromosome 8 at 35,812,339 bp (GRCm38)
  • T to C, chromosome 8 at 41,083,185 bp (GRCm38)
  • T to C, chromosome 8 at 86,548,759 bp (GRCm38)
  • C to T, chromosome 8 at 119,471,774 bp (GRCm38)
  • T to C, chromosome 9 at 31,172,007 bp (GRCm38)
  • A to C, chromosome 9 at 37,918,770 bp (GRCm38)
  • A to T, chromosome 9 at 64,156,021 bp (GRCm38)
  • A to T, chromosome 9 at 103,356,340 bp (GRCm38)
  • T to C, chromosome 9 at 110,085,035 bp (GRCm38)
  • A to T, chromosome 10 at 75,743,256 bp (GRCm38)
  • T to A, chromosome 11 at 3,650,381 bp (GRCm38)
  • A to G, chromosome 11 at 31,081,400 bp (GRCm38)
  • C to A, chromosome 11 at 36,024,514 bp (GRCm38)
  • T to A, chromosome 11 at 44,525,003 bp (GRCm38)
  • T to C, chromosome 11 at 50,969,489 bp (GRCm38)
  • T to C, chromosome 11 at 55,179,343 bp (GRCm38)
  • A to T, chromosome 11 at 73,887,870 bp (GRCm38)
  • G to T, chromosome 11 at 79,516,145 bp (GRCm38)
  • A to G, chromosome 11 at 115,893,541 bp (GRCm38)
  • T to A, chromosome 12 at 58,267,646 bp (GRCm38)
  • A to T, chromosome 12 at 76,564,952 bp (GRCm38)
  • A to G, chromosome 12 at 100,573,991 bp (GRCm38)
  • G to T, chromosome 12 at 112,658,451 bp (GRCm38)
  • A to G, chromosome 12 at 112,773,034 bp (GRCm38)
  • T to A, chromosome 12 at 113,702,338 bp (GRCm38)
  • A to G, chromosome 13 at 3,599,667 bp (GRCm38)
  • A to G, chromosome 13 at 23,034,338 bp (GRCm38)
  • G to A, chromosome 13 at 54,738,901 bp (GRCm38)
  • T to C, chromosome 15 at 8,645,693 bp (GRCm38)
  • A to G, chromosome 15 at 34,530,081 bp (GRCm38)
  • G to A, chromosome 15 at 36,190,537 bp (GRCm38)
  • T to A, chromosome 15 at 80,690,618 bp (GRCm38)
  • C to T, chromosome 15 at 86,130,550 bp (GRCm38)
  • A to G, chromosome 15 at 89,336,582 bp (GRCm38)
  • A to G, chromosome 17 at 20,357,000 bp (GRCm38)
  • T to C, chromosome 17 at 43,310,689 bp (GRCm38)
  • G to C, chromosome 17 at 56,717,843 bp (GRCm38)
  • T to C, chromosome 18 at 36,974,356 bp (GRCm38)
  • T to C, chromosome 18 at 46,560,591 bp (GRCm38)
  • T to C, chromosome 18 at 78,856,927 bp (GRCm38)
  • A to G, chromosome 18 at 90,590,945 bp (GRCm38)
  • A to G, chromosome 19 at 4,166,008 bp (GRCm38)
  • G to T, chromosome 19 at 21,423,085 bp (GRCm38)
  • A to G, chromosome 19 at 43,495,030 bp (GRCm38)
  • A to T, chromosome 19 at 61,127,562 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
Gene Specific Genotyping:

To request gene-specific and other genotyping services for a strain, please contact the distribution MMRRC Center for more information.

Background Genetic Quality:

The MMRRC has developed a Genetic Quality Control pipeline using the MiniMUGA array to provide additional information to identify and validate genetic backgrounds of MMRRC strains. For more information on whether genetic background data is available, please contact MMRRC_GeneticQC@med.unc.edu. Note: that MiniMUGA genetic background data is not available on all strains, but can be ordered if desired.

Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9711 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069958-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.