Strain Name:
C57BL/6J-MtgxR9714Btlr/Mmmh
Stock Number:
069961-MU
Citation ID:
RRID:MMRRC_069961-MU
Other Names:
R9714 (G1)
Major Collection:

Strain Information

Med13l
Name: mediator complex subunit 13-like
Synonyms: 9030618F05Rik, Trap240L, Thrap2, 6330591G05Rik, 2210413I17Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 76199
Homologene: 25256
Plxna1
Name: plexin A1
Synonyms: NOV, Plxn1, PlexA1, 2600013D04Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 18844
HGNC: HGNC:9099
Homologene: 56426
Parvb
Name: parvin, beta
Synonyms: affixin, D15Gsk1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 170736
Homologene: 8342
Mms19
Name: MMS19 cytosolic iron-sulfur assembly component
Synonyms: 2610042O15Rik, C86341, Mms19, Mms19l
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 72199
Homologene: 41480
Tiam1
Name: T cell lymphoma invasion and metastasis 1
Synonyms: D16Ium10e, D16Ium10
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 21844
Homologene: 2443
Taf11
Name: TATA-box binding protein associated factor 11
Synonyms: PRO214, TAF2I, TAFII28, 1110038O14Rik, 28kDa
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 68776
Homologene: 55918
Tbc1d10a
Name: TBC1 domain family, member 10a
Synonyms: EPI64, Tbc1d10
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103724
Homologene: 32762
Ptprc
Name: protein tyrosine phosphatase receptor type C
Synonyms: CD45, T200, Ly-5, Lyt-4, B220
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19264
HGNC: HGNC:9666
Homologene: 2126
Glg1
Name: golgi apparatus protein 1
Synonyms: CFR, Selel, CFR-1, MG-160, MG160, ESL-1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 20340
HGNC: HGNC:4316
Homologene: 7533
Myo19
Name: myosin XIX
Synonyms: 1110055A02Rik, Myohd1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 66196
Homologene: 49819
Nup153
Name: nucleoporin 153
Synonyms: B130015D15Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218210
HGNC: HGNC:8062
Homologene: 68442
Abca16
Name: ATP-binding cassette, sub-family A member 16
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233810
Homologene: 132942
Abca3
Name: ATP-binding cassette, sub-family A member 3
Synonyms: ABC-C, Abc3, 1810036E22Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 27410
HGNC: HGNC:33
Homologene: 37437
Pcdh10
Name: protocadherin 10
Synonyms: 6430521D13Rik, OL-pc, 6430703F07Rik, Olpc
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18526
Homologene: 74967
Vwf
Name: Von Willebrand factor
Synonyms: B130011O06Rik, 6820430P06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 22371
Homologene: 466
Cd19
Name: CD19 antigen
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12478
HGNC: HGNC:1633
Homologene: 1341
Styk1
Name: serine/threonine/tyrosine kinase 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243659
Homologene: 49545
Col17a1
Name: collagen, type XVII, alpha 1
Synonyms: Bpag, BP180, BPAg2, Bpag2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 12821
HGNC: HGNC:2194
Homologene: 7276
Sardh
Name: sarcosine dehydrogenase
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 192166
Homologene: 5149
Notum
Name: notum palmitoleoyl-protein carboxylesterase
Synonyms: 5730593N15Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 77583
Homologene: 45335
Rsad1
Name: radical S-adenosyl methionine domain containing 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237926
Homologene: 41252
Dok1
Name: docking protein 1
Synonyms: p62DOK
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 13448
HGNC: HGNC:2990
Homologene: 1057
Kif1c
Name: kinesin family member 1C
Synonyms: N-3 kinsin, B430105J22Rik, D11Bwg1349e, Orch3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16562
HGNC: HGNC:6317
Homologene: 4821
Pla2g4f
Name: phospholipase A2, group IVF
Synonyms: 4732472I07Rik, Pla2zeta
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 271844
Homologene: 77933
Krt79
Name: keratin 79
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223917
Homologene: 89169
Pmm2
Name: phosphomannomutase 2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 54128
HGNC: HGNC:9115
Homologene: 257
Crb2
Name: crumbs family member 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241324
Homologene: 45474
Hsd3b6
Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6
Synonyms: 3beta-HSD VI
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 15497
Homologene: 133013
Slc35a5
Name: solute carrier family 35, member A5
Synonyms: 1010001J06Rik, D730043G07Rik, D16Ertd450e
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74102
Homologene: 9930
Vmn2r31
Name: vomeronasal 2, receptor 31
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100042591
Homologene: 113703
Slc35f3
Name: solute carrier family 35, member F3
Synonyms: B230375D17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 210027
Homologene: 62481
AC157566.4
Name:
Type: Gene
Species: Mouse
Chromosome: 15
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 138,080,949 bp (GRCm38)
  • C to T, chromosome 2 at 27,189,629 bp (GRCm38)
  • G to A, chromosome 2 at 37,791,203 bp (GRCm38)
  • C to T, chromosome 2 at 120,312,419 bp (GRCm38)
  • G to A, chromosome 3 at 45,381,575 bp (GRCm38)
  • A to G, chromosome 3 at 98,806,329 bp (GRCm38)
  • T to A, chromosome 5 at 118,728,373 bp (GRCm38)
  • A to G, chromosome 6 at 83,031,294 bp (GRCm38)
  • A to T, chromosome 6 at 89,319,458 bp (GRCm38)
  • G to A, chromosome 6 at 125,624,573 bp (GRCm38)
  • CTCTTCATGATTTTCTT to CTCTT, chromosome 6 at 131,301,649 bp (GRCm38)
  • T to A, chromosome 7 at 7,384,368 bp (GRCm38)
  • A to C, chromosome 7 at 120,431,160 bp (GRCm38)
  • T to C, chromosome 7 at 126,411,058 bp (GRCm38)
  • A to G, chromosome 8 at 111,197,669 bp (GRCm38)
  • CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC to CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC, chromosome 8 at 126,389,042 bp (GRCm38)
  • G to T, chromosome 11 at 4,213,683 bp (GRCm38)
  • T to C, chromosome 11 at 70,724,834 bp (GRCm38)
  • A to G, chromosome 11 at 84,882,716 bp (GRCm38)
  • A to G, chromosome 11 at 94,544,472 bp (GRCm38)
  • T to C, chromosome 11 at 120,660,193 bp (GRCm38)
  • G to A, chromosome 13 at 46,712,959 bp (GRCm38)
  • T to C, chromosome 15 at 76,534,154 bp (GRCm38)
  • G to T, chromosome 15 at 84,282,840 bp (GRCm38)
  • T to G, chromosome 15 at 101,930,761 bp (GRCm38)
  • T to C, chromosome 16 at 8,655,642 bp (GRCm38)
  • T to C, chromosome 16 at 45,144,063 bp (GRCm38)
  • T to A, chromosome 16 at 89,897,759 bp (GRCm38)
  • T to A, chromosome 17 at 24,376,728 bp (GRCm38)
  • T to C, chromosome 17 at 27,903,162 bp (GRCm38)
  • A to G, chromosome 19 at 41,946,971 bp (GRCm38)
  • C to T, chromosome 19 at 47,648,195 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9714 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069961-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.