Strain Name:
C57BL/6J-MtgxR9738Btlr/Mmmh
Stock Number:
069984-MU
Citation ID:
RRID:MMRRC_069984-MU
Other Names:
R9738 (G1)
Major Collection:

Strain Information

Cntnap2
Name: contactin associated protein-like 2
Synonyms: 5430425M22Rik, Caspr2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 66797
Homologene: 69159
Ank2
Name: ankyrin 2, brain
Synonyms: ankyrin B, Gm4392, Ankyrin-B, Ank-2, Ankyrin-2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 109676
HGNC: HGNC:493
Lars1
Name: leucyl-tRNA synthetase 1
Synonyms: 2310045K21Rik, Lars, 3110009L02Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 107045
VEGA: 18
HGNC: HGNC:6512
Homologene: 7083
Cdk8
Name: cyclin dependent kinase 8
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 264064
HGNC: HGNC:1779
Homologene: 55565
Usp1
Name: ubiquitin specific peptidase 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230484
Homologene: 2528
Ltn1
Name: listerin E3 ubiquitin protein ligase 1
Synonyms: 4930528H02Rik, Listerin, Zfp294, Rnf160
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 78913
VEGA: 16
Homologene: 32272
Clasp2
Name: CLIP associating protein 2
Synonyms: 8030404L10Rik, CLASP2gamma, CLASP2beta, CLASP2, 1500004F14Rik, CLASP2alpha
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 76499
VEGA: 9
Homologene: 24944
Tjp1
Name: tight junction protein 1
Synonyms: ZO-1, ZO1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 21872
Homologene: 2445
Bnip3l
Name: BCL2/adenovirus E1B interacting protein 3-like
Synonyms: Nip3L, Nix, D14Ertd719e
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12177
HGNC: HGNC:1085
Homologene: 3195
Sugp1
Name: SURP and G patch domain containing 1
Synonyms: Sf4
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 70616
Homologene: 12360
Crtc1
Name: CREB regulated transcription coactivator 1
Synonyms: Mect1, TORC1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382056
Homologene: 41607
Wdtc1
Name: WD and tetratricopeptide repeats 1
Synonyms: adipose, LOC230796, adp
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230796
Homologene: 8997
Myh6
Name: myosin, heavy polypeptide 6, cardiac muscle, alpha
Synonyms: Myhc-a, alpha cardiac MHC, Myhca, alphaMHC, alpha myosin, A830009F23Rik, cardiomyopathy, hypertrophic 1, alpha-MHC
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 17888
HGNC: HGNC:7576
Homologene: 124414
Hivep2
Name: human immunodeficiency virus type I enhancer binding protein 2
Synonyms: Schnurri-2, MIBP1, Gm20114, Shn-2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 15273
HGNC: HGNC:4921
Homologene: 4900
Myh7b
Name: myosin, heavy chain 7B, cardiac muscle, beta
Synonyms: Myh14
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 668940
Homologene: 66117
Cdh5
Name: cadherin 5
Synonyms: 7B4/cadherin-5, VE-Cad, VEcad, VE-cadherin, CD144, VECD, VEC
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12562
HGNC: HGNC:1764
Homologene: 1359
Ndrg2
Name: N-myc downstream regulated gene 2
Synonyms: Ndr2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 29811
VEGA: 14
Homologene: 22785
Zfp947
Name: zinc finger protein 947
Synonyms: Gm4769
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 210853
Homologene: 133253
Unc5d
Name: unc-5 netrin receptor D
Synonyms: D930029E11Rik, Unc5h4
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 210801
Homologene: 15450
Spag17
Name: sperm associated antigen 17
Synonyms: PF6, 4931427F14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74362
Homologene: 52601
Abhd12b
Name: abhydrolase domain containing 12B
Synonyms: LOC328121
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 100504285
Homologene: 128243
Iqsec1
Name: IQ motif and Sec7 domain 1
Synonyms: BRAG2, cI-43, D6Ertd349e
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232227
Homologene: 82429
Cpne9
Name: copine family member IX
Synonyms: A730016F12Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 211232
Homologene: 84686
Tsnaxip1
Name: translin-associated factor X (Tsnax) interacting protein 1
Synonyms: TXI1, 1700016K08Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72236
Homologene: 10194
Hrh4
Name: histamine receptor H4
Synonyms: H4R
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225192
VEGA: 18
Homologene: 11002
Cpxm1
Name: carboxypeptidase X, M14 family member 1
Synonyms: Cpx-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 56264
Homologene: 10485
Lgr5
Name: leucine rich repeat containing G protein coupled receptor 5
Synonyms: Gpr49
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 14160
HGNC: HGNC:4504
Homologene: 20807
Atg12
Name: autophagy related 12
Synonyms: 4931423H11Rik, A330058M13Rik, Apg12l
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 67526
VEGA: 18
HGNC: HGNC:588
Homologene: 37953
Or5an11
Name: olfactory receptor family 5 subfamily AN member 11
Synonyms: Olfr235, Olfr232, Olfr245, MOR214-3, GA_x6K02T2LL2P-1028-792, MOR214-3, GA_x6K02T057QT-4025-4642, GA_x6K02T03CT6-1-477
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258681
Gm12888
Name: predicted gene 12888
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 545677
Homologene: 111034
Msrb1
Name: methionine sulfoxide reductase B1
Synonyms: Sepx1, Sepr, SelR, D17Wsu82e
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 27361
Homologene: 8455
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 2 at 130,393,382 bp (GRCm38)
  • A to G, chromosome 2 at 155,614,043 bp (GRCm38)
  • A to G, chromosome 3 at 100,027,210 bp (GRCm38)
  • A to G, chromosome 3 at 126,943,472 bp (GRCm38)
  • T to C, chromosome 4 at 98,931,435 bp (GRCm38)
  • A to T, chromosome 4 at 121,318,323 bp (GRCm38)
  • A to G, chromosome 4 at 133,295,293 bp (GRCm38)
  • A to G, chromosome 5 at 146,299,729 bp (GRCm38)
  • CCACATAAACAACACACA to CCACA, chromosome 6 at 46,015,439 bp (GRCm38)
  • G to A, chromosome 6 at 90,694,690 bp (GRCm38)
  • A to C, chromosome 6 at 113,290,440 bp (GRCm38)
  • T to C, chromosome 7 at 65,336,632 bp (GRCm38)
  • T to A, chromosome 8 at 28,724,304 bp (GRCm38)
  • T to A, chromosome 8 at 70,052,606 bp (GRCm38)
  • T to C, chromosome 8 at 70,387,555 bp (GRCm38)
  • A to G, chromosome 8 at 104,136,697 bp (GRCm38)
  • A to G, chromosome 8 at 105,841,758 bp (GRCm38)
  • T to A, chromosome 9 at 113,761,597 bp (GRCm38)
  • A to G, chromosome 10 at 14,143,839 bp (GRCm38)
  • A to G, chromosome 10 at 115,452,622 bp (GRCm38)
  • A to G, chromosome 12 at 70,169,265 bp (GRCm38)
  • T to C, chromosome 14 at 51,910,781 bp (GRCm38)
  • T to C, chromosome 14 at 54,952,302 bp (GRCm38)
  • G to A, chromosome 14 at 67,008,765 bp (GRCm38)
  • A to T, chromosome 16 at 87,425,636 bp (GRCm38)
  • A to G, chromosome 17 at 22,146,360 bp (GRCm38)
  • T to C, chromosome 17 at 24,739,561 bp (GRCm38)
  • A to G, chromosome 18 at 13,022,213 bp (GRCm38)
  • A to G, chromosome 18 at 42,217,584 bp (GRCm38)
  • A to G, chromosome 18 at 46,741,438 bp (GRCm38)
  • A to G, chromosome 19 at 12,268,505 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9738 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069984-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.