Strain Name:
C57BL/6J-MtgxR9761Btlr/Mmmh
Stock Number:
070006-MU
Citation ID:
RRID:MMRRC_070006-MU
Other Names:
R9761 (G1)
Major Collection:

Strain Information

Lhx9
Name: LIM homeobox protein 9
Synonyms: LH2B, Lhx9 alpha, 3110009O07Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16876
Homologene: 7816
Lrrc2
Name: leucine rich repeat containing 2
Synonyms: 2400002D05Rik, 4933431K03Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74249
Homologene: 23454
Tmprss12
Name: transmembrane (C-terminal) protease, serine 12
Synonyms: 4930478A21Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 75002
VEGA: 15
Homologene: 16598
Dgkh
Name: diacylglycerol kinase, eta
Synonyms: 5930402B05Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 380921
VEGA: 14
HGNC: HGNC:2854
Homologene: 99373
Ticrr
Name: TOPBP1-interacting checkpoint and replication regulator
Synonyms: 5730590G19Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 77011
Homologene: 67120
Gcn1
Name: GCN1 activator of EIF2AK4
Synonyms: GCN1L, G431004K08Rik, Gcn1l1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231659
HGNC: HGNC:4199
Homologene: 5887
Helz
Name: helicase with zinc finger domain
Synonyms: 9630002H22Rik, 9430093I07Rik, 3110078M01Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 78455
Homologene: 8918
Syne1
Name: spectrin repeat containing, nuclear envelope 1
Synonyms: nesprin-1, SYNE-1, enaptin165, A330049M09Rik, C130039F11Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 64009
VEGA: 10
Homologene: 52329
Vps50
Name: VPS50 EARP/GARPII complex subunit
Synonyms: 8430415E05Rik, 1700034M03Rik, Ccdc132
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 73288
Homologene: 11498
Serpina3c
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3C
Synonyms: Kalbp, 1A1, Klkbp, alpha-1 antiproteinase
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16625
HGNC: HGNC:16
Homologene: 111129
Mansc1
Name: MANSC domain containing 1
Synonyms: 9130403P13Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67729
Homologene: 49522
Itfg1
Name: integrin alpha FG-GAP repeat containing 1
Synonyms: 2310047C21Rik, D8Wsu49e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71927
Homologene: 12423
Ift81
Name: intraflagellar transport 81
Synonyms: CDV-1R, Cdv1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12589
Homologene: 7664
Gzf1
Name: GDNF-inducible zinc finger protein 1
Synonyms: 8430437G08Rik, Zfp336
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74533
Homologene: 11200
Pprc1
Name: peroxisome proliferative activated receptor, gamma, coactivator-related 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226169
Homologene: 9006
Tnrc6c
Name: trinucleotide repeat containing 6C
Synonyms: 9930033H14Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217351
Homologene: 23137
Gpr152
Name: G protein-coupled receptor 152
Synonyms: LOC269053, A930009H15Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 269053
VEGA: 19
Homologene: 35474
Cfap74
Name: cilia and flagella associated protein 74
Synonyms: 2010015L04Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 544678
Homologene: 129584
Akap3
Name: A kinase anchor protein 3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 11642
HGNC: HGNC:373
Homologene: 4688
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 545370
Homologene: 23741
Myh13
Name: myosin, heavy polypeptide 13, skeletal muscle
Synonyms: extraocular myosin, EO Myosin, MyHC-eo
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 544791
HGNC: HGNC:7571
Homologene: 55780
Ankrd35
Name: ankyrin repeat domain 35
Synonyms: 4732436F15Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213121
Homologene: 16977
Zim1
Name: zinc finger, imprinted 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22776
Homologene: 129793
Gbp5
Name: guanylate binding protein 5
Synonyms: 5330409J06Rik, Gbp5a
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229898
Homologene: 14183
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241516
Homologene: 110349
Scn2a
Name: sodium channel, voltage-gated, type II, alpha
Synonyms: Nav1.2, A230052E19Rik, Scn2a1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 110876
Homologene: 75001
Or4f53
Name: olfactory receptor family 4 subfamily F member 53
Synonyms: GA_x6K02T2Q125-72308574-72309512, MOR245-10, Olfr1276
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258390
Homologene: 133614
Atp11b
Name: ATPase, class VI, type 11B
Synonyms: 1110019I14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 76295
Homologene: 32919
Tnxb
Name: tenascin XB
Synonyms: Tnx, TN-MHC
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 81877
Homologene: 49589
Abcc9
Name: ATP-binding cassette, sub-family C member 9
Synonyms: SUR2B, SUR2A, Sur2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20928
HGNC: HGNC:60
Homologene: 56521
Dpp6
Name: dipeptidylpeptidase 6
Synonyms: Dpp-6, Peplb, In(5)6H-p, Rw, LOC384168, B930011P16Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13483
HGNC: HGNC:3010
Homologene: 22560
Greb1
Name: gene regulated by estrogen in breast cancer protein
Synonyms: 5730583K22Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 268527
Homologene: 8780
Elp4
Name: elongator acetyltransferase complex subunit 4
Synonyms: A330107A17Rik, Paxneb
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 77766
HGNC: HGNC:1171
Homologene: 32433
Ablim3
Name: actin binding LIM protein family, member 3
Synonyms: D930036B08Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 319713
VEGA: 18
Homologene: 69175
Pfpl
Name: pore forming protein-like
Synonyms: Epcs5, Epcs50
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 56093
VEGA: 19
Homologene: 130704
Klk1b1
Name: kallikrein 1-related peptidase b1
Synonyms: mGK-1, TK, tissue kallikrein, mK1, Klk1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16623
Homologene: 68141
Or8g26
Name: olfactory receptor family 8 subfamily G member 26
Synonyms: GA_x6K02T2PVTD-32881408-32882343, MOR171-44, Olfr943
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258323
VEGA: 9
HGNC: HGNC:8484
Homologene: 110526
Or14j7
Name: olfactory receptor family 14 subfamily J member 7
Synonyms: GA_x6K02T2PSCP-2374126-2375048, MOR218-13, Olfr128
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 383243
Homologene: 134080
Slc23a3
Name: solute carrier family 23 (nucleobase transporters), member 3
Synonyms: SVCT3, Yspl1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22626
Homologene: 65865
Prkar1b
Name: protein kinase, cAMP dependent regulatory, type I beta
Synonyms: RIbeta
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19085
HGNC: HGNC:9390
Homologene: 37665
Poc1b
Name: POC1 centriolar protein B
Synonyms: 4933430F16Rik, Wdr51b
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 382406
Homologene: 41728
Ms4a19
Name: membrane-spanning 4-domains, subfamily A, member 19
Synonyms: 1700025F22Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 69416
Homologene: 137380
Or12d13
Name: olfactory receptor family 12 subfamily D member 13
Synonyms: MOR250-3, GA_x6K02T2PSCP-1798423-1797482, MOR250-8_p, Olfr103
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258830
Homologene: 115555
Klrg2
Name: killer cell lectin-like receptor subfamily G, member 2
Synonyms: 2310020F24Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74253
Homologene: 52362
Or8k20
Name: olfactory receptor family 8 subfamily K member 20
Synonyms: GA_x6K02T2Q125-47756192-47755266, MOR187-5, Olfr1051
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 404324
Homologene: 77387
Klk1b24
Name: kallikrein 1-related peptidase b24
Synonyms: mGk-24, Klk24
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16617
Homologene: 68141
Mcidas
Name: multiciliate differentiation and DNA synthesis associated cell cycle protein
Synonyms: Gm6320, Idas, multicilin, Mci, Mcin
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 622408
VEGA: 13
Homologene: 83681
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • ATT to ATTT, chromosome 1 at 75,133,281 bp (GRCm38)
  • T to C, chromosome 1 at 138,847,196 bp (GRCm38)
  • T to C, chromosome 1 at 150,992,874 bp (GRCm38)
  • A to G, chromosome 2 at 65,735,686 bp (GRCm38)
  • A to T, chromosome 2 at 82,991,650 bp (GRCm38)
  • C to T, chromosome 2 at 86,275,806 bp (GRCm38)
  • C to T, chromosome 2 at 105,794,559 bp (GRCm38)
  • C to A, chromosome 2 at 111,257,261 bp (GRCm38)
  • T to G, chromosome 2 at 111,257,262 bp (GRCm38)
  • C to T, chromosome 2 at 148,688,091 bp (GRCm38)
  • A to T, chromosome 3 at 35,849,458 bp (GRCm38)
  • G to T, chromosome 3 at 35,849,467 bp (GRCm38)
  • C to T, chromosome 3 at 35,849,472 bp (GRCm38)
  • C to T, chromosome 3 at 96,684,417 bp (GRCm38)
  • A to G, chromosome 3 at 142,507,757 bp (GRCm38)
  • C to A, chromosome 4 at 155,466,387 bp (GRCm38)
  • G to A, chromosome 5 at 27,664,745 bp (GRCm38)
  • A to G, chromosome 5 at 115,591,005 bp (GRCm38)
  • A to C, chromosome 5 at 122,591,083 bp (GRCm38)
  • C to A, chromosome 5 at 139,106,655 bp (GRCm38)
  • T to A, chromosome 6 at 3,519,218 bp (GRCm38)
  • C to A, chromosome 6 at 38,630,352 bp (GRCm38)
  • A to G, chromosome 6 at 126,865,237 bp (GRCm38)
  • A to T, chromosome 6 at 134,610,041 bp (GRCm38)
  • G to A, chromosome 6 at 142,599,128 bp (GRCm38)
  • G to C, chromosome 7 at 6,677,772 bp (GRCm38)
  • C to A, chromosome 7 at 43,969,315 bp (GRCm38)
  • A to T, chromosome 7 at 44,190,355 bp (GRCm38)
  • A to G, chromosome 7 at 79,695,565 bp (GRCm38)
  • T to C, chromosome 8 at 85,836,402 bp (GRCm38)
  • T to C, chromosome 9 at 39,184,850 bp (GRCm38)
  • A to G, chromosome 9 at 110,980,874 bp (GRCm38)
  • A to G, chromosome 10 at 5,368,190 bp (GRCm38)
  • C to T, chromosome 10 at 99,129,494 bp (GRCm38)
  • A to G, chromosome 11 at 67,360,468 bp (GRCm38)
  • C to A, chromosome 11 at 107,670,048 bp (GRCm38)
  • T to A, chromosome 11 at 117,732,310 bp (GRCm38)
  • C to T, chromosome 12 at 16,701,274 bp (GRCm38)
  • G to T, chromosome 12 at 104,151,830 bp (GRCm38)
  • G to A, chromosome 13 at 112,998,919 bp (GRCm38)
  • A to T, chromosome 14 at 78,651,723 bp (GRCm38)
  • T to C, chromosome 15 at 100,292,648 bp (GRCm38)
  • A to G, chromosome 17 at 34,685,013 bp (GRCm38)
  • T to A, chromosome 17 at 37,337,166 bp (GRCm38)
  • T to C, chromosome 17 at 37,924,043 bp (GRCm38)
  • C to A, chromosome 18 at 61,819,814 bp (GRCm38)
  • T to C, chromosome 19 at 4,143,228 bp (GRCm38)
  • T to C, chromosome 19 at 11,142,390 bp (GRCm38)
  • G to C, chromosome 19 at 12,428,933 bp (GRCm38)
  • A to G, chromosome 19 at 46,061,559 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9761 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
070006-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.