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Strain Name:
C57BL/6J-MtgxR9765Btlr/Mmmh
Stock Number:
070010-MU
Citation ID:
RRID:MMRRC_070010-MU
Other Names:
R9765 (G1)
Major Collection:

Strain Information

Utrn
Name: utrophin
Synonyms: G-utrophin, Dmdl, DRP
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 22288
VEGA: 10
Homologene: 21398
Ift70b
Name: intraflagellar transport 70B
Synonyms: 2510042P03Rik, Ttc30b
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 72421
Homologene: 71716
Dhx35
Name: DEAH-box helicase 35
Synonyms: Ddx35, 1200009D07Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71715
Homologene: 6406
Eml4
Name: echinoderm microtubule associated protein like 4
Synonyms: 4930443C24Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 78798
VEGA: 17
HGNC: HGNC:1316
Homologene: 56841
Ipo11
Name: importin 11
Synonyms: E330021B14Rik, 1700081H05Rik, 2510001A17Rik, Ranbp11
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 76582
Homologene: 7089
Gcn1
Name: GCN1 activator of EIF2AK4
Synonyms: GCN1L, G431004K08Rik, Gcn1l1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231659
HGNC: HGNC:4199
Homologene: 5887
Slain2
Name: SLAIN motif family, member 2
Synonyms: 8030444K12Rik, 5033405K12Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 75991
Homologene: 18952
Zc3h3
Name: zinc finger CCCH type containing 3
Synonyms: Smicl
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223642
VEGA: 15
Homologene: 9029
Evi5
Name: ecotropic viral integration site 5
Synonyms: NB4S
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14020
HGNC: HGNC:3501
Homologene: 121902
Gtpbp4
Name: GTP binding protein 4
Synonyms: 2610028C09Rik, Crfg, Nog1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 69237
VEGA: 13
Homologene: 7100
Eef2
Name: eukaryotic translation elongation factor 2
Synonyms: Ef-2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 13629
VEGA: 10
HGNC: HGNC:3214
Homologene: 134867
Gtf2f1
Name: general transcription factor IIF, polypeptide 1
Synonyms: 2810405L04Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 98053
VEGA: 17
HGNC: HGNC:4652
Homologene: 1585
Cdca8
Name: cell division cycle associated 8
Synonyms: 4831429J16Rik, D4Ertd421e, DasraB, Borealin
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 52276
Homologene: 23075
Ash1l
Name: ASH1 like histone lysine methyltransferase
Synonyms: chromatin remodeling factor, 8030453L17Rik, E430018P19Rik, KMT2H
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 192195
Homologene: 10225
Mdh1
Name: malate dehydrogenase 1, NAD (soluble)
Synonyms: Mor-2, MDH-s, Mor2, B230377B03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17449
HGNC: HGNC:6970
Homologene: 4324
Rcn1
Name: reticulocalbin 1
Synonyms: Rcn
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19672
HGNC: HGNC:9934
Homologene: 20637
Iqgap3
Name: IQ motif containing GTPase activating protein 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 404710
Homologene: 26400
Dsg4
Name: desmoglein 4
Synonyms: lah, CDHF13
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 16769
Homologene: 65341
Glud1
Name: glutamate dehydrogenase 1
Synonyms: Gdh-X, Glud
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 14661
Homologene: 55885
Ifnar2
Name: interferon (alpha and beta) receptor 2
Synonyms: Ifnar-2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 15976
HGNC: HGNC:5433
Homologene: 49242
Zfp953
Name: zinc finger protein 953
Synonyms: E130120F12Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 629016
Cux2
Name: cut-like homeobox 2
Synonyms: Cux-2, Cux2, ENSMUSG00000072641, Cutl2, 1700051K22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13048
Homologene: 22426
Cdh19
Name: cadherin 19, type 2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227485
HGNC: HGNC:1758
Homologene: 23286
Muc16
Name: mucin 16
Synonyms: LOC385009, 1110008I14Rik, Gm21044
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73732
Homologene: 141193
Map3k7
Name: mitogen-activated protein kinase kinase kinase 7
Synonyms: Tak1, TGF-beta activated kinase 1, transforming growth factor-beta-activated kinase 1, TAK1, transforming growth factor beta-activated kinase 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 26409
HGNC: HGNC:6859
Homologene: 118818
Srpra
Name: signal recognition particle receptor alpha
Synonyms: 1300011P19Rik, D11Mgi27, Srpr
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67398
Homologene: 2364
Dennd2a
Name: DENN domain containing 2A
Synonyms: B930096L08Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 209773
Homologene: 35238
Kifc5b
Name: kinesin family member C5B
Synonyms: kinesin family c-terminal 5B
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16580
VEGA: 17
HGNC: HGNC:6389
Homologene: 83229
St3gal1
Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 1
Synonyms: CMP-N-acetylneuraminate: [beta-galactosidase alpha-2,3] sialytransferase, Siat4, ST3GalI, Siat4a
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20442
VEGA: 15
Homologene: 7540
Dock8
Name: dedicator of cytokinesis 8
Synonyms: 1200017A24Rik, 5830472H07Rik, A130095G14Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 76088
VEGA: 19
Homologene: 52414
Col4a3
Name: collagen, type IV, alpha 3
Synonyms: alpha3(IV), tumstatin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12828
HGNC: HGNC:2204
Homologene: 68033
Adgrf5
Name: adhesion G protein-coupled receptor F5
Synonyms: 8430401C09Rik, Gpr116
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224792
VEGA: 17
Homologene: 9065
Myo16
Name: myosin XVI
Synonyms: C230040D10Rik, Nyap3, BM140241
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244281
Homologene: 34710
Fam124a
Name: family with sequence similarity 124, member A
Synonyms: EG629059
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 629059
Homologene: 86241
Naip5
Name: NLR family, apoptosis inhibitory protein 5
Synonyms: Naip-rs3, Birc1e, Lgn1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17951
HGNC: HGNC:7634
Homologene: 113589
Cul9
Name: cullin 9
Synonyms: 1810035I07Rik, Parc
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 78309
Homologene: 56696
Plb1
Name: phospholipase B1
Synonyms: 4632413E21Rik, 4930433E17Rik, 4930539A06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 665270
Homologene: 82108
Zfp458
Name: zinc finger protein 458
Synonyms: Rslcan-7
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238690
VEGA: 13
Homologene: 128170
Dgkg
Name: diacylglycerol kinase, gamma
Synonyms: Dagk3, E430001K23Rik, 2900055E17Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 110197
HGNC: HGNC:2853
Homologene: 1029
Cntnap4
Name: contactin associated protein-like 4
Synonyms: Caspr4, E130114F09Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 170571
Homologene: 24912
Dnase1l2
Name: deoxyribonuclease 1-like 2
Synonyms: 4733401H14Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 66705
HGNC: HGNC:2958
Homologene: 74391
Slc30a4
Name: solute carrier family 30 (zinc transporter), member 4
Synonyms: Znt4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22785
Homologene: 74984
Tmem208
Name: transmembrane protein 208
Synonyms: 2610030K20Rik, 1700006C06Rik, Hspc171
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66320
Homologene: 40930
Spef2
Name: sperm flagellar 2
Synonyms: C230086A09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 320277
Homologene: 23371
Ppp4r4
Name: protein phosphatase 4, regulatory subunit 4
Synonyms: 8430415E04Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 74521
Homologene: 12571
Dpy19l3
Name: dpy-19 like C-mannosyltransferase 3
Synonyms: 9330164H19Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233115
Homologene: 18692
Fbxw21
Name: F-box and WD-40 domain protein 21
Synonyms: E330009P21Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320082
Homologene: 110776
Slc26a7
Name: solute carrier family 26, member 7
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 208890
Homologene: 13770
Zbtb37
Name: zinc finger and BTB domain containing 37
Synonyms: D430004I08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240869
Homologene: 13048
Noxo1
Name: NADPH oxidase organizer 1
Synonyms: 2310034C04Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 71893
Homologene: 12418
Fn3krp
Name: fructosamine 3 kinase related protein
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 238024
Homologene: 11093
Cyp3a13
Name: cytochrome P450, family 3, subfamily a, polypeptide 13
Synonyms: IIIAm2, steroid inducible
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13113
Homologene: 133564
Rbm20
Name: RNA binding motif protein 20
Synonyms: 2010003H22Rik, 1110018J23Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 73713
Homologene: 28386
Samhd1
Name: SAM domain and HD domain, 1
Synonyms: E330031J07Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 56045
Homologene: 9160
Cimip6
Name: ciliary microtubule inner protein 6
Synonyms: 4930505A04Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 75087
Homologene: 18988
Peli3
Name: pellino 3
Synonyms: 6030441F14Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 240518
Homologene: 27059
Ces2f
Name: carboxylesterase 2F
Synonyms: 2310038E17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71903
HGNC: HGNC:1864
Homologene: 135673
Or4k49
Name: olfactory receptor family 4 subfamily K member 49
Synonyms: GA_x6K02T2Q125-72715642-72716580, MOR248-8, Olfr1299
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258886
Homologene: 17426
Tas2r136
Name: taste receptor, type 2, member 136
Synonyms: mt2r52, Tas2r36
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 353165
Homologene: 136304
Retreg1
Name: reticulophagy regulator 1
Synonyms: 1810015C04Rik, Fam134b
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66270
VEGA: 15
Homologene: 10368
Actr1b
Name: ARP1 actin-related protein 1B, centractin beta
Synonyms: Arp1b, 2310066K23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226977
HGNC: HGNC:168
Homologene: 101541
Zfp40
Name: zinc finger protein 40
Synonyms: NTfin12, Zfp-40
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22700
Homologene: 136312
Cacng4
Name: calcium channel, voltage-dependent, gamma subunit 4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 54377
HGNC: HGNC:1408
Homologene: 8674
Cks1brt
Name: CDC28 protein kinase 1b, retrogene
Synonyms: Gm6531
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 624855
Homologene: 83385
Rrm2
Name: ribonucleotide reductase M2
Synonyms: R2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20135
Homologene: 20277
Pcdhgb6
Name: protocadherin gamma subfamily B, 6
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93703
HGNC: HGNC:8713
Homologene: 49573
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 36,702,596 bp (GRCm38)
  • G to A, chromosome 1 at 82,668,957 bp (GRCm38)
  • A to G, chromosome 1 at 110,895,381 bp (GRCm38)
  • T to C, chromosome 1 at 161,031,862 bp (GRCm38)
  • A to T, chromosome 2 at 75,938,123 bp (GRCm38)
  • A to T, chromosome 2 at 105,394,681 bp (GRCm38)
  • T to A, chromosome 2 at 111,664,885 bp (GRCm38)
  • A to T, chromosome 2 at 122,694,536 bp (GRCm38)
  • G to T, chromosome 2 at 157,123,299 bp (GRCm38)
  • C to T, chromosome 2 at 158,829,581 bp (GRCm38)
  • G to A, chromosome 3 at 88,110,054 bp (GRCm38)
  • T to A, chromosome 3 at 89,023,193 bp (GRCm38)
  • A to T, chromosome 4 at 14,522,862 bp (GRCm38)
  • A to T, chromosome 4 at 32,019,519 bp (GRCm38)
  • A to G, chromosome 4 at 124,920,329 bp (GRCm38)
  • T to A, chromosome 5 at 32,355,387 bp (GRCm38)
  • T to A, chromosome 5 at 72,957,626 bp (GRCm38)
  • A to C, chromosome 5 at 107,799,254 bp (GRCm38)
  • G to A, chromosome 5 at 115,597,072 bp (GRCm38)
  • G to A, chromosome 5 at 121,869,132 bp (GRCm38)
  • G to C, chromosome 5 at 137,911,621 bp (GRCm38)
  • C to T, chromosome 6 at 39,496,973 bp (GRCm38)
  • T to A, chromosome 6 at 132,777,850 bp (GRCm38)
  • T to C, chromosome 7 at 35,708,631 bp (GRCm38)
  • C to A, chromosome 8 at 10,570,401 bp (GRCm38)
  • A to G, chromosome 8 at 85,171,605 bp (GRCm38)
  • A to G, chromosome 8 at 104,950,046 bp (GRCm38)
  • A to G, chromosome 8 at 105,334,874 bp (GRCm38)
  • T to C, chromosome 8 at 112,757,478 bp (GRCm38)
  • T to C, chromosome 8 at 112,841,864 bp (GRCm38)
  • C to A, chromosome 9 at 18,637,198 bp (GRCm38)
  • T to C, chromosome 9 at 35,211,374 bp (GRCm38)
  • A to G, chromosome 9 at 109,146,557 bp (GRCm38)
  • T to A, chromosome 10 at 12,735,177 bp (GRCm38)
  • T to A, chromosome 10 at 81,179,176 bp (GRCm38)
  • G to T, chromosome 11 at 21,562,926 bp (GRCm38)
  • C to T, chromosome 11 at 30,454,829 bp (GRCm38)
  • A to G, chromosome 11 at 107,741,983 bp (GRCm38)
  • A to G, chromosome 11 at 121,421,478 bp (GRCm38)
  • A to G, chromosome 12 at 24,708,957 bp (GRCm38)
  • G to T, chromosome 12 at 103,584,087 bp (GRCm38)
  • T to A, chromosome 13 at 8,974,958 bp (GRCm38)
  • C to T, chromosome 13 at 67,260,153 bp (GRCm38)
  • T to C, chromosome 13 at 67,292,810 bp (GRCm38)
  • A to T, chromosome 13 at 67,343,414 bp (GRCm38)
  • C to G, chromosome 13 at 100,230,761 bp (GRCm38)
  • A to G, chromosome 13 at 106,925,048 bp (GRCm38)
  • C to T, chromosome 14 at 34,338,838 bp (GRCm38)
  • T to G, chromosome 14 at 62,587,434 bp (GRCm38)
  • A to T, chromosome 15 at 9,601,859 bp (GRCm38)
  • G to A, chromosome 15 at 25,940,899 bp (GRCm38)
  • T to C, chromosome 15 at 67,109,650 bp (GRCm38)
  • T to G, chromosome 15 at 75,837,610 bp (GRCm38)
  • T to C, chromosome 16 at 22,479,407 bp (GRCm38)
  • G to A, chromosome 16 at 91,388,087 bp (GRCm38)
  • A to T, chromosome 17 at 23,176,889 bp (GRCm38)
  • A to T, chromosome 17 at 24,441,075 bp (GRCm38)
  • G to T, chromosome 17 at 24,696,412 bp (GRCm38)
  • A to G, chromosome 17 at 26,923,265 bp (GRCm38)
  • G to A, chromosome 17 at 43,437,600 bp (GRCm38)
  • A to T, chromosome 17 at 46,539,298 bp (GRCm38)
  • G to A, chromosome 17 at 57,011,125 bp (GRCm38)
  • A to G, chromosome 17 at 83,440,069 bp (GRCm38)
  • G to A, chromosome 18 at 20,471,277 bp (GRCm38)
  • A to T, chromosome 18 at 37,743,001 bp (GRCm38)
  • A to T, chromosome 19 at 4,941,822 bp (GRCm38)
  • T to G, chromosome 19 at 25,169,468 bp (GRCm38)
  • T to G, chromosome 19 at 53,851,629 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9765 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
070010-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.