Strain Name:
C57BL/6J-MtgxR9766Btlr/Mmmh
Stock Number:
070011-MU
Citation ID:
RRID:MMRRC_070011-MU
Other Names:
R9766 (G1)
Major Collection:

Strain Information

Myo5a
Name: myosin VA
Synonyms: MVa, MyoVA, Dbv, flail, 9630007J19Rik, Myo5
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17918
HGNC: HGNC:7602
Homologene: 20100
Vcan
Name: versican
Synonyms: PG-M, hdf, heart defect, 5430420N07Rik, DPEAAE, Cspg2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 13003
HGNC: HGNC:2464
Homologene: 3228
Ptf1a
Name: pancreas specific transcription factor, 1a
Synonyms: PTF1-p48, bHLHa29
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19213
Homologene: 10304
Crybg3
Name: beta-gamma crystallin domain containing 3
Synonyms: Gm9581
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224273
Homologene: 28544
Serinc3
Name: serine incorporator 3
Synonyms: TMS-1, DIFF33, AIGP1, Tde1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 26943
Homologene: 38230
Wdfy3
Name: WD repeat and FYVE domain containing 3
Synonyms: 2610509D04Rik, Ggtb3, D5Ertd66e, Bwf1, Bchs, Alfy
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72145
Homologene: 22855
Lrsam1
Name: leucine rich repeat and sterile alpha motif containing 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227738
Homologene: 44526
Usp14
Name: ubiquitin specific peptidase 14
Synonyms: dUB-type TGT, 2610005K12Rik, ataxia, ax, NMF375, 2610037B11Rik, nmf375
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 59025
Homologene: 3780
Rfx1
Name: regulatory factor X, 1 (influences HLA class II expression)
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 19724
HGNC: HGNC:9982
Homologene: 2189
Knl1
Name: kinetochore scaffold 1
Synonyms: 2310043D08Rik, Casc5, 5730505K17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 76464
Homologene: 44890
Trappc8
Name: trafficking protein particle complex 8
Synonyms: 5033403J15Rik, D030074E01Rik, Trs85
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 75964
VEGA: 18
Homologene: 40993
Anapc1
Name: anaphase promoting complex subunit 1
Synonyms: 2610021O03Rik, tsg24, Mcpr, Apc1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17222
Homologene: 7414
Eif2ak4
Name: eukaryotic translation initiation factor 2 alpha kinase 4
Synonyms: GCN2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 27103
Homologene: 40891
Bltp3a
Name: bridge-like lipid transfer protein family member 3A
Synonyms: 1110020K19Rik, F830021D11Rik, Uhrf1bp1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224648
Homologene: 9816
Zfp407
Name: zinc finger protein 407
Synonyms: LOC381139, LOC240469, 6430585N13Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240476
Homologene: 86402
Taf2
Name: TATA-box binding protein associated factor 2
Synonyms: TAFII150, CIF150, TAF2B, 4732460C16Rik, 150kDa
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 319944
VEGA: 15
Homologene: 31137
Arhgap17
Name: Rho GTPase activating protein 17
Synonyms: Rich1, Nadrin2, Nadrin, 5730403H17Rik, WBP15
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 70497
Homologene: 9984
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: A930005E13Rik, LOC381562, D930005K06Rik, 1810009A16Rik, Zubr1, p600
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69116
Homologene: 10804
Muc16
Name: mucin 16
Synonyms: 1110008I14Rik, LOC385009, Gm21044
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73732
Homologene: 141193
Zfp644
Name: zinc finger protein 644
Synonyms: 1110068L01Rik, BM-005, Zep-2, D5Ertd689e
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 52397
Homologene: 12971
Ankrd26
Name: ankyrin repeat domain 26
Synonyms: 5730521P14Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232339
Homologene: 45968
Hrob
Name: homologous recombination factor with OB-fold
Synonyms: BC030867
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217216
Homologene: 69368
L1td1
Name: LINE-1 type transposase domain containing 1
Synonyms: ECAT11
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 381591
Homologene: 135709
Fgf5
Name: fibroblast growth factor 5
Synonyms: Fgf-5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14176
HGNC: HGNC:3683
Homologene: 3283
Pitpnm1
Name: phosphatidylinositol transfer protein, membrane-associated 1
Synonyms: RdgB, DRES9
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18739
HGNC: HGNC:9003
Homologene: 3608
Kcnd2
Name: potassium voltage-gated channel, Shal-related family, member 2
Synonyms: Kv4.2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16508
HGNC: HGNC:6238
Homologene: 40828
Patl2
Name: protein associated with topoisomerase II homolog 2 (yeast)
Synonyms: 4930424G05Rik, Pat1a
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 67578
Homologene: 12155
Art3
Name: ADP-ribosyltransferase 3
Synonyms: 4930569O04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 109979
HGNC: HGNC:725
Homologene: 911
Dock3
Name: dedicator of cyto-kinesis 3
Synonyms: PBP, Moca
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 208869
HGNC: HGNC:2989
Homologene: 21030
Ccdc88b
Name: coiled-coil domain containing 88B
Synonyms: 2610041P08Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 78317
VEGA: 19
Homologene: 49992
Gprc6a
Name: G protein-coupled receptor, family C, group 6, member A
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 210198
VEGA: 10
Homologene: 17529
Edem1
Name: ER degradation enhancer, mannosidase alpha-like 1
Synonyms: A130059K23Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 192193
Homologene: 33836
Phf8l
Name: PHD finger protein 8 like
Synonyms: 4921501E09Rik, Phf8-ps
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 74042
VEGA: 17
Homologene: 66275
Hecw2
Name: HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
Synonyms: A730039N16Rik, D030049F17Rik, Nedl2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329152
Homologene: 66192
AI661453
Name: expressed sequence AI661453
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224833
Homologene: 138294
Ddx60
Name: DExD/H box helicase 60
Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234311
Homologene: 23031
Aatk
Name: apoptosis-associated tyrosine kinase
Synonyms: AATYK1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11302
HGNC: HGNC:21
Homologene: 74861
Pcnx2
Name: pecanex homolog 2
Synonyms: E330039K12Rik, Pcnxl2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 270109
HGNC: HGNC:8736
Homologene: 8987
Ppp4r4
Name: protein phosphatase 4, regulatory subunit 4
Synonyms: 8430415E04Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 74521
Homologene: 12571
Ces1e
Name: carboxylesterase 1E
Synonyms: Eg, egasyn, Es-22, Es22
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 13897
HGNC: HGNC:1863
Homologene: 115660
Acsbg3
Name: acyl-CoA synthetase bubblegum family member 3
Synonyms: 1700061G19Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 78625
Homologene: 28378
3425401B19Rik
Name: RIKEN cDNA 3425401B19 gene
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 100504518
VEGA: 14
Homologene: 54908
Scn11a
Name: sodium channel, voltage-gated, type XI, alpha
Synonyms: SNS2, NaN, NaT, NSS2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 24046
VEGA: 9
Homologene: 8041
Rnf207
Name: ring finger protein 207
Synonyms: D330010C22Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 433809
Homologene: 19234
Sdr39u1
Name: short chain dehydrogenase/reductase family 39U, member 1
Synonyms: 2310014G06Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 654795
VEGA: 14
Homologene: 69295
Dus2
Name: dihydrouridine synthase 2
Synonyms: 2310016K04Rik, Dus2l
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66369
Homologene: 6838
Tex26
Name: testis expressed 26
Synonyms: 4930588N13Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 75860
Homologene: 51841
Dpep3
Name: dipeptidase 3
Synonyms: MBD-3, 1700018F16Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71854
Homologene: 23357
Stambp
Name: STAM binding protein
Synonyms: 5330424L14Rik, 5730422L11Rik, Amsh
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 70527
Homologene: 4719
Pira2
Name: paired-Ig-like receptor A2
Synonyms: 6M23
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18725
Homologene: 134028
Acox1
Name: acyl-Coenzyme A oxidase 1, palmitoyl
Synonyms: D130055E20Rik, Acyl-CoA oxidase, AOX
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11430
HGNC: HGNC:119
Homologene: 38299
Flot1
Name: flotillin 1
Synonyms: reggie-2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14251
HGNC: HGNC:3757
Homologene: 31337
Rasgrf2
Name: RAS protein-specific guanine nucleotide-releasing factor 2
Synonyms: Grf2, 6330417G04Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 19418
HGNC: HGNC:9876
Homologene: 2169
Gsta2
Name: glutathione S-transferase, alpha 2 (Yc2)
Synonyms: Gstc2, Gstc-2, Gst2-2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 14858
Homologene: 74378
Nkd2
Name: naked cuticle 2
Synonyms: 2210403L10Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 72293
Homologene: 12459
Bmp5
Name: bone morphogenetic protein 5
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12160
HGNC: HGNC:1072
Homologene: 22412
Ebna1bp2
Name: EBNA1 binding protein 2
Synonyms: p40, Nobp, B830003A16Rik, Ebp2, 1810014B19Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69072
Homologene: 4969
Efcab8
Name: EF-hand calcium binding domain 8
Synonyms: EG329541
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 100504221
Crtac1
Name: cartilage acidic protein 1
Synonyms: 2810454P21Rik, Lotus, Crtac1B
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 72832
VEGA: 19
Homologene: 23070
Cib3
Name: calcium and integrin binding family member 3
Synonyms: C730014M21Rik, KIP3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234421
Homologene: 14287
Tmem258
Name: transmembrane protein 258
Synonyms: 1810006K21Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 69038
HGNC: HGNC:1164
Homologene: 40931
Fbxw27
Name: F-box and WD-40 domain protein 27
Synonyms: 1700124P09Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 76998
Homologene: 110776
Speer4a3
Name: spermatogenesis associated glutamate (E)-rich protein 4A3
Synonyms: Gm21671
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100862359
Homologene: 69402
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 53,865,128 bp (GRCm38)
  • G to A, chromosome 2 at 19,446,251 bp (GRCm38)
  • G to T, chromosome 2 at 32,928,065 bp (GRCm38)
  • A to T, chromosome 2 at 118,430,832 bp (GRCm38)
  • A to G, chromosome 2 at 119,069,900 bp (GRCm38)
  • A to T, chromosome 2 at 122,123,731 bp (GRCm38)
  • C to T, chromosome 2 at 128,658,301 bp (GRCm38)
  • A to T, chromosome 2 at 153,814,442 bp (GRCm38)
  • T to C, chromosome 2 at 163,629,175 bp (GRCm38)
  • T to C, chromosome 2 at 175,170,455 bp (GRCm38)
  • T to C, chromosome 4 at 98,736,516 bp (GRCm38)
  • T to C, chromosome 4 at 118,623,624 bp (GRCm38)
  • T to C, chromosome 4 at 139,467,284 bp (GRCm38)
  • C to A, chromosome 4 at 152,315,945 bp (GRCm38)
  • AACT to A, chromosome 5 at 25,950,851 bp (GRCm38)
  • T to C, chromosome 5 at 92,414,279 bp (GRCm38)
  • A to G, chromosome 5 at 98,275,254 bp (GRCm38)
  • C to T, chromosome 5 at 101,895,000 bp (GRCm38)
  • C to A, chromosome 5 at 106,636,825 bp (GRCm38)
  • A to T, chromosome 5 at 149,463,177 bp (GRCm38)
  • T to C, chromosome 6 at 21,216,368 bp (GRCm38)
  • C to A, chromosome 6 at 83,557,487 bp (GRCm38)
  • T to A, chromosome 6 at 108,846,687 bp (GRCm38)
  • T to C, chromosome 6 at 118,523,106 bp (GRCm38)
  • T to A, chromosome 7 at 3,842,518 bp (GRCm38)
  • A to G, chromosome 7 at 123,321,925 bp (GRCm38)
  • G to A, chromosome 8 at 62,012,278 bp (GRCm38)
  • A to T, chromosome 8 at 72,207,190 bp (GRCm38)
  • C to T, chromosome 8 at 84,087,747 bp (GRCm38)
  • A to T, chromosome 8 at 93,219,403 bp (GRCm38)
  • A to C, chromosome 8 at 105,978,737 bp (GRCm38)
  • A to G, chromosome 8 at 106,045,936 bp (GRCm38)
  • A to G, chromosome 8 at 125,761,574 bp (GRCm38)
  • T to A, chromosome 9 at 18,636,857 bp (GRCm38)
  • T to A, chromosome 9 at 18,641,087 bp (GRCm38)
  • T to C, chromosome 9 at 75,171,632 bp (GRCm38)
  • A to G, chromosome 9 at 75,893,700 bp (GRCm38)
  • A to T, chromosome 9 at 78,337,594 bp (GRCm38)
  • A to C, chromosome 9 at 106,911,284 bp (GRCm38)
  • T to C, chromosome 9 at 109,773,147 bp (GRCm38)
  • T to G, chromosome 9 at 119,755,115 bp (GRCm38)
  • G to A, chromosome 10 at 51,615,788 bp (GRCm38)
  • A to T, chromosome 11 at 102,255,760 bp (GRCm38)
  • G to A, chromosome 11 at 116,181,041 bp (GRCm38)
  • A to T, chromosome 11 at 120,011,739 bp (GRCm38)
  • T to C, chromosome 12 at 103,596,476 bp (GRCm38)
  • G to T, chromosome 13 at 73,847,012 bp (GRCm38)
  • A to G, chromosome 13 at 89,691,128 bp (GRCm38)
  • G to T, chromosome 13 at 92,023,680 bp (GRCm38)
  • A to G, chromosome 14 at 32,663,831 bp (GRCm38)
  • C to T, chromosome 14 at 55,897,737 bp (GRCm38)
  • T to C, chromosome 15 at 55,047,485 bp (GRCm38)
  • A to T, chromosome 16 at 59,555,844 bp (GRCm38)
  • T to C, chromosome 17 at 27,886,825 bp (GRCm38)
  • T to G, chromosome 17 at 33,066,673 bp (GRCm38)
  • G to T, chromosome 17 at 35,830,663 bp (GRCm38)
  • C to T, chromosome 17 at 47,446,645 bp (GRCm38)
  • A to G, chromosome 17 at 56,882,177 bp (GRCm38)
  • G to A, chromosome 18 at 10,005,630 bp (GRCm38)
  • A to G, chromosome 18 at 20,846,573 bp (GRCm38)
  • T to C, chromosome 18 at 84,559,449 bp (GRCm38)
  • T to C, chromosome 19 at 4,108,117 bp (GRCm38)
  • T to A, chromosome 19 at 6,855,728 bp (GRCm38)
  • T to C, chromosome 19 at 10,207,214 bp (GRCm38)
  • A to T, chromosome 19 at 42,414,118 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9766 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
070011-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.