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Strain Name:
C57BL/6J-MtgxR9798Btlr/Mmmh
Stock Number:
070043-MU
Citation ID:
RRID:MMRRC_070043-MU
Other Names:
R9798 (G1)
Major Collection:

Strain Information

Sptbn4
Name: spectrin beta, non-erythrocytic 4
Synonyms: dyn, SpbIV, neuroaxonal dystrophy, 5830426A08Rik, ROSA62, nmf261, 1700022P15Rik, Spnb4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 80297
Homologene: 11879
Pias3
Name: protein inhibitor of activated STAT 3
Synonyms: Pias3L
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229615
Homologene: 4447
Il23a
Name: interleukin 23, alpha subunit p19
Synonyms: p19, IL-23, IL-23p19
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 83430
VEGA: 10
Homologene: 12832
Slc4a7
Name: solute carrier family 4, sodium bicarbonate cotransporter, member 7
Synonyms: E430014N10Rik, NBC3, NBCn1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218756
VEGA: 14
Homologene: 2680
Slc1a6
Name: solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
Synonyms: EAAT4
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20513
VEGA: 10
Homologene: 21055
Fryl
Name: FRY like transcription coactivator
Synonyms: 2310004H21Rik, 2510002A14Rik, 9030227G01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72313
Homologene: 103956
Fgfr1
Name: fibroblast growth factor receptor 1
Synonyms: Flt-2, Fgfr-1, Hspy, Eask, FGFR-I, Fr1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14182
HGNC: HGNC:3688
Homologene: 69065
Bbx
Name: bobby sox HMG box containing
Synonyms: 5730403O13Rik, 5530401J07Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 70508
Homologene: 10634
Vps13c
Name: vacuolar protein sorting 13C
Synonyms: C230055H22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320528
VEGA: 9
Homologene: 41188
Scaf4
Name: SR-related CTD-associated factor 4
Synonyms: Sra4, Sfrs15, Srsf15
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224432
VEGA: 16
Homologene: 16227
Adamtsl1
Name: ADAMTS-like 1
Synonyms: punctin-1, 6720426B09Rik, 5930437A14Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 77739
Homologene: 64642
Tmod3
Name: tropomodulin 3
Synonyms: UTMOD, U-Tmod, ubiquitous tropomodulin
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 50875
VEGA: 9
Homologene: 8727
Tex15
Name: testis expressed gene 15 meiosis and synapsis associated
Synonyms: 2210014E14Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 104271
Homologene: 12837
Ush2a
Name: usherin
Synonyms: MUSH2A, A930011D15Rik, LOC381317, LOC269160, A930037M10Rik, Ushrn, Ush2a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22283
Homologene: 66151
Trappc14
Name: trafficking protein particle complex 14
Synonyms: Map11, BC037034
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231807
Homologene: 10106
Bbs7
Name: Bardet-Biedl syndrome 7
Synonyms: 8430406N16Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71492
Homologene: 12395
Hipk1
Name: homeodomain interacting protein kinase 1
Synonyms: Myak, 1110062K04Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 15257
Homologene: 56483
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241516
Homologene: 110349
Asns
Name: asparagine synthetase
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 27053
HGNC: HGNC:753
Homologene: 69113
Wdr31
Name: WD repeat domain 31
Synonyms: 5430402I10Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 71354
Homologene: 11360
Or8u10
Name: olfactory receptor family 8 subfamily U member 10
Synonyms: GA_x6K02T2Q125-47560740-47559775, MOR256-34P, MOR171-52, Olfr1037
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 259151
Homologene: 66572
Ahnak
Name: AHNAK nucleoprotein
Synonyms: DY6, 2310047C17Rik, 1110004P15Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Igsf10
Name: immunoglobulin superfamily, member 10
Synonyms: 6530405F15Rik, CMF608, Adlican2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242050
Homologene: 18712
Alpk3
Name: alpha-kinase 3
Synonyms: Midori
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 116904
Homologene: 10813
Top2b
Name: topoisomerase (DNA) II beta
Synonyms: Top-2, D230016L12Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 21974
Homologene: 134711
Celsr3
Name: cadherin, EGF LAG seven-pass G-type receptor 3
Synonyms: Fmi1, flamingo, Adgrc3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 107934
HGNC: HGNC:3230
Homologene: 1077
4930486L24Rik
Name: RIKEN cDNA 4930486L24 gene
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 214639
VEGA: 13
Homologene: 138410
Espnl
Name: espin-like
Synonyms: LOC227357
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227357
Homologene: 77795
Slco1b2
Name: solute carrier organic anion transporter family, member 1b2
Synonyms: mlst-1, Slc21a6, Slc21a10, Oatp1b2, 7330442B20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 28253
Homologene: 75119
Vmn1r178
Name: vomeronasal 1 receptor 178
Synonyms: LOC232959, V1rd13
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232959
Homologene: 104166
Phtf1
Name: putative homeodomain transcription factor 1
Synonyms: Phft
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18685
HGNC: HGNC:8939
Homologene: 4817
Kctd11
Name: potassium channel tetramerisation domain containing 11
Synonyms: Ren
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216858
Homologene: 17697
Fktn
Name: fukutin
Synonyms: Fukutin, Fcmd
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 246179
HGNC: HGNC:3622
Homologene: 31402
Msln
Name: mesothelin
Synonyms: megakaryocyte potentiating factor, MPF
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 56047
VEGA: 17
HGNC: HGNC:7371
Homologene: 4249
Entpd1
Name: ectonucleoside triphosphate diphosphohydrolase 1
Synonyms: NTPDase-1, Cd39, ectoapyrase, 2610206B08Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 12495
HGNC: HGNC:3363
Homologene: 20423
Synpo
Name: synaptopodin
Synonyms: 9330140I15Rik, 9030217H17Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 104027
Homologene: 5274
Ston1
Name: stonin 1
Synonyms: 4921524J06Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 77057
Homologene: 122152
Igsf5
Name: immunoglobulin superfamily, member 5
Synonyms: 2010003D20Rik, Igsf5, Jam4
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 72058
HGNC: HGNC:5952
Homologene: 12437
Ripor1
Name: RHO family interacting cell polarization regulator 1
Synonyms: 2310066E14Rik, Fam65a
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 75687
Homologene: 11564
Or7g29
Name: olfactory receptor family 7 subfamily G member 29
Synonyms: GA_x6K02T2PVTD-13113073-13112135, MOR149-2, Olfr847
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258518
Homologene: 17281
Psmc2
Name: proteasome (prosome, macropain) 26S subunit, ATPase 2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19181
HGNC: HGNC:9548
Homologene: 2096
Rrh
Name: retinal pigment epithelium derived rhodopsin homolog
Synonyms: Peropsin
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20132
Homologene: 55977
Cc2d2b
Name: coiled-coil and C2 domain containing 2B
Synonyms: EG668310
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 668310
Homologene: 141114
Gm21698
Name: predicted gene, 21698
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100862388
Homologene: 69402
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • G to T, chromosome 1 at 91,323,564 bp (GRCm38)
  • A to G, chromosome 1 at 188,911,805 bp (GRCm38)
  • T to A, chromosome 2 at 82,979,881 bp (GRCm38)
  • T to C, chromosome 2 at 86,085,262 bp (GRCm38)
  • A to T, chromosome 3 at 36,598,290 bp (GRCm38)
  • T to A, chromosome 3 at 59,331,705 bp (GRCm38)
  • T to C, chromosome 3 at 96,699,565 bp (GRCm38)
  • C to T, chromosome 3 at 103,744,115 bp (GRCm38)
  • T to C, chromosome 3 at 103,997,553 bp (GRCm38)
  • C to T, chromosome 3 at 129,811,772 bp (GRCm38)
  • C to T, chromosome 4 at 53,747,128 bp (GRCm38)
  • A to G, chromosome 4 at 62,463,414 bp (GRCm38)
  • A to G, chromosome 4 at 86,156,690 bp (GRCm38)
  • A to G, chromosome 5 at 21,795,808 bp (GRCm38)
  • A to T, chromosome 5 at 25,984,186 bp (GRCm38)
  • T to C, chromosome 5 at 73,035,059 bp (GRCm38)
  • A to G, chromosome 5 at 138,261,678 bp (GRCm38)
  • T to C, chromosome 6 at 7,689,395 bp (GRCm38)
  • C to A, chromosome 6 at 141,655,353 bp (GRCm38)
  • C to A, chromosome 7 at 23,894,308 bp (GRCm38)
  • T to C, chromosome 7 at 27,357,292 bp (GRCm38)
  • T to A, chromosome 7 at 81,092,652 bp (GRCm38)
  • C to T, chromosome 8 at 25,563,507 bp (GRCm38)
  • T to A, chromosome 8 at 33,572,693 bp (GRCm38)
  • T to C, chromosome 8 at 105,616,166 bp (GRCm38)
  • T to A, chromosome 9 at 19,375,281 bp (GRCm38)
  • T to A, chromosome 9 at 67,919,364 bp (GRCm38)
  • G to T, chromosome 9 at 75,529,519 bp (GRCm38)
  • G to C, chromosome 9 at 75,529,521 bp (GRCm38)
  • A to C, chromosome 9 at 75,529,523 bp (GRCm38)
  • A to T, chromosome 9 at 108,828,595 bp (GRCm38)
  • G to A, chromosome 10 at 78,793,333 bp (GRCm38)
  • G to C, chromosome 10 at 128,296,960 bp (GRCm38)
  • T to G, chromosome 11 at 69,879,906 bp (GRCm38)
  • A to T, chromosome 13 at 60,853,120 bp (GRCm38)
  • A to G, chromosome 14 at 14,782,056 bp (GRCm38)
  • T to C, chromosome 14 at 16,389,845 bp (GRCm38)
  • T to C, chromosome 16 at 50,224,758 bp (GRCm38)
  • G to A, chromosome 16 at 90,248,645 bp (GRCm38)
  • C to A, chromosome 16 at 96,372,875 bp (GRCm38)
  • T to C, chromosome 17 at 25,753,797 bp (GRCm38)
  • T to C, chromosome 17 at 88,637,044 bp (GRCm38)
  • A to T, chromosome 18 at 60,603,760 bp (GRCm38)
  • A to G, chromosome 19 at 9,013,619 bp (GRCm38)
  • G to A, chromosome 19 at 40,727,345 bp (GRCm38)
  • G to A, chromosome 19 at 40,794,636 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9798 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
070043-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.