Strain Name:
C57BL/6J-MtgxR9801Btlr/Mmmh
Stock Number:
070046-MU
Citation ID:
RRID:MMRRC_070046-MU
Other Names:
R9801 (G1)
Major Collection:

Strain Information

Smarca4
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Synonyms: SNF2beta, SW1/SNF, Brg1, b2b692Clo, b2b508.1Clo
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20586
Homologene: 135927
Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Rnf145
Name: ring finger protein 145
Synonyms: 3732413I11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74315
Homologene: 14427
Pum1
Name: pumilio RNA-binding family member 1
Synonyms: Pumm
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 80912
Homologene: 22830
Dip2c
Name: disco interacting protein 2 homolog C
Synonyms: 2900024P20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 208440
Homologene: 40996
Anks1
Name: ankyrin repeat and SAM domain containing 1
Synonyms: Odin
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224650
Homologene: 9068
Uba3
Name: ubiquitin-like modifier activating enzyme 3
Synonyms: Ube1c, ubiquitin activating enzyme 3, A830034N06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 22200
Homologene: 2951
Cstf3
Name: cleavage stimulation factor, 3' pre-RNA, subunit 3
Synonyms: 4732468G05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228410
HGNC: HGNC:2485
Homologene: 1014
Nbr1
Name: NBR1, autophagy cargo receptor
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17966
HGNC: HGNC:6746
Homologene: 7438
Cntrob
Name: centrobin, centrosomal BRCA2 interacting protein
Synonyms: Lip8, 9830165K03Rik, Nip2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216846
Homologene: 14205
Trappc10
Name: trafficking protein particle complex 10
Synonyms: b2b2613Clo, Tmem1, LOC380642, b2b2416Clo, B230307C21Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216131
VEGA: 10
Homologene: 37751
Plxna4
Name: plexin A4
Synonyms: Plxa4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243743
HGNC: HGNC:9102
Homologene: 77587
Pemt
Name: phosphatidylethanolamine N-methyltransferase
Synonyms: Pempt, Pempt2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18618
HGNC: HGNC:8830
Homologene: 6291
Galr1
Name: galanin receptor 1
Synonyms: Galnr1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 14427
VEGA: 18
HGNC: HGNC:4132
Homologene: 74396
Rbl2
Name: RB transcriptional corepressor like 2
Synonyms: Rb2, p130, retinoblastoma-like 2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 19651
HGNC: HGNC:9894
Homologene: 4098
Extl3
Name: exostosin-like glycosyltransferase 3
Synonyms: 2900009G18Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 54616
VEGA: 14
HGNC: HGNC:3518
Homologene: 1103
Mfsd14b
Name: major facilitator superfamily domain containing 14B
Synonyms: 5730414C17Rik, Hiatl1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66631
Homologene: 64464
Slmap
Name: sarcolemma associated protein
Synonyms: Miranda, D330001L02Rik, Slap
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 83997
Homologene: 31428
Svil
Name: supervillin
Synonyms: B430302E16Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225115
Homologene: 25090
Taf4b
Name: TATA-box binding protein associated factor 4b
Synonyms: 105kDa, 4932409F03Rik, Taf2c2, TAFII105, 2610524B04Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 72504
VEGA: 18
Homologene: 28266
Pkd1l1
Name: polycystic kidney disease 1 like 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 171395
Homologene: 51376
Tet3
Name: tet methylcytosine dioxygenase 3
Synonyms: B430006D22Rik, D230004J03Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 194388
Homologene: 35360
Polq
Name: polymerase (DNA directed), theta
Synonyms: A430110D14Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 77782
HGNC: HGNC:9186
Homologene: 32727
Nr1i3
Name: nuclear receptor subfamily 1, group I, member 3
Synonyms: CAR1, MB67, Care2, ESTM32, mCAR, CAR
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12355
HGNC: HGNC:7969
Homologene: 3759
Acss3
Name: acyl-CoA synthetase short-chain family member 3
Synonyms: LOC380660, 8430416H19Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 380660
Homologene: 11587
Me3
Name: malic enzyme 3, NADP(+)-dependent, mitochondrial
Synonyms: B230207H15Rik, 1700020C08Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 109264
HGNC: HGNC:6985
Homologene: 100773
Bbox1
Name: gamma-butyrobetaine hydroxylase 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 170442
HGNC: HGNC:964
Homologene: 2967
Cbr1
Name: carbonyl reductase 1
Synonyms: CR
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12408
HGNC: HGNC:1548
Homologene: 37524
Cdcp2
Name: CUB domain containing protein 2
Synonyms: D030010E02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242603
Homologene: 138406
Ctbs
Name: chitobiase
Synonyms: 2210401K11Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74245
HGNC: HGNC:2496
Homologene: 3231
Tll2
Name: tolloid-like 2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 24087
VEGA: 19
Homologene: 56545
H2-M10.4
Name: histocompatibility 2, M region locus 10.4
Synonyms: 15H
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224753
Homologene: 117973
Fam83d
Name: family with sequence similarity 83, member D
Synonyms: 2310007D09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71878
Homologene: 23715
Cylc2
Name: cylicin, basic protein of sperm head cytoskeleton 2
Synonyms: 4930488P18Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74914
HGNC: HGNC:2583
Homologene: 136270
Rxylt1
Name: ribitol xylosyltransferase 1
Synonyms: 6330415D21Rik, Tmem5
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216395
Homologene: 8600
Scgb2b7
Name: secretoglobin, family 2B, member 7
Synonyms: Gm4684, Abpbg7
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100043836
Homologene: 83171
Psg22
Name: pregnancy-specific beta-1-glycoprotein 22
Synonyms: cea9
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243862
HGNC: HGNC:1816
Homologene: 110989
Dus4l
Name: dihydrouridine synthase 4 like
Synonyms: 2700089B10Rik, 2310069P03Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 71916
VEGA: 12
Homologene: 6535
Atg12
Name: autophagy related 12
Synonyms: 4931423H11Rik, A330058M13Rik, Apg12l
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 67526
VEGA: 18
HGNC: HGNC:588
Homologene: 37953
Glra3
Name: glycine receptor, alpha 3 subunit
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 110304
HGNC: HGNC:4328
Homologene: 142
Btbd3
Name: BTB domain containing 3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228662
4930447C04Rik
Name: RIKEN cDNA 4930447C04 gene
Synonyms: Six6as, Six6os1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 75801
Homologene: 49922
Klra7
Name: killer cell lectin-like receptor, subfamily A, member 7
Synonyms: LGL-1, Ly49g, Ly-49G.3, Ly-49G.2, Ly-49G.1, Ly49g2, Ly49g1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16638
Homologene: 110821
Vwa1
Name: von Willebrand factor A domain containing 1
Synonyms: WARP, 4932416A11Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 246228
Homologene: 11270
Zfp260
Name: zinc finger protein 260
Synonyms: Zfp63, PEX1, Ozrf1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 26466
Homologene: 40802
4933402J07Rik
Name: RIKEN cDNA 4933402J07 gene
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 330820
Homologene: 51633
Tcp10b
Name: t-complex protein 10b
Synonyms: D17Leh66B, Tcp-10bt, D17Leh66ba, T66B-a, Tcp-10b
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21462
Homologene: 83254
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 171,217,683 bp (GRCm38)
  • T to C, chromosome 2 at 104,590,679 bp (GRCm38)
  • T to A, chromosome 2 at 110,270,073 bp (GRCm38)
  • C to T, chromosome 2 at 138,280,448 bp (GRCm38)
  • T to A, chromosome 2 at 158,768,390 bp (GRCm38)
  • T to C, chromosome 3 at 146,463,924 bp (GRCm38)
  • T to A, chromosome 4 at 51,228,466 bp (GRCm38)
  • A to T, chromosome 4 at 107,107,065 bp (GRCm38)
  • C to T, chromosome 4 at 130,754,017 bp (GRCm38)
  • G to A, chromosome 4 at 155,772,879 bp (GRCm38)
  • C to T, chromosome 6 at 32,163,591 bp (GRCm38)
  • T to A, chromosome 6 at 83,369,454 bp (GRCm38)
  • T to A, chromosome 6 at 97,185,674 bp (GRCm38)
  • C to T, chromosome 6 at 130,228,514 bp (GRCm38)
  • T to C, chromosome 7 at 18,722,974 bp (GRCm38)
  • T to C, chromosome 7 at 30,105,512 bp (GRCm38)
  • A to T, chromosome 7 at 31,705,155 bp (GRCm38)
  • A to C, chromosome 7 at 89,786,449 bp (GRCm38)
  • G to A, chromosome 8 at 56,110,528 bp (GRCm38)
  • A to G, chromosome 8 at 87,564,089 bp (GRCm38)
  • T to C, chromosome 8 at 91,095,601 bp (GRCm38)
  • G to T, chromosome 9 at 21,675,101 bp (GRCm38)
  • A to G, chromosome 10 at 78,209,429 bp (GRCm38)
  • T to C, chromosome 10 at 107,045,230 bp (GRCm38)
  • T to A, chromosome 10 at 122,090,703 bp (GRCm38)
  • C to A, chromosome 11 at 8,958,964 bp (GRCm38)
  • T to A, chromosome 11 at 44,557,285 bp (GRCm38)
  • T to A, chromosome 11 at 59,983,461 bp (GRCm38)
  • T to C, chromosome 11 at 69,321,407 bp (GRCm38)
  • C to A, chromosome 11 at 101,556,199 bp (GRCm38)
  • A to G, chromosome 12 at 31,648,828 bp (GRCm38)
  • A to T, chromosome 12 at 72,898,766 bp (GRCm38)
  • T to C, chromosome 13 at 9,576,900 bp (GRCm38)
  • T to A, chromosome 13 at 13,634,705 bp (GRCm38)
  • C to A, chromosome 13 at 65,073,600 bp (GRCm38)
  • G to A, chromosome 14 at 26,422,440 bp (GRCm38)
  • A to T, chromosome 14 at 65,077,333 bp (GRCm38)
  • C to T, chromosome 16 at 37,092,828 bp (GRCm38)
  • A to C, chromosome 16 at 93,609,799 bp (GRCm38)
  • A to G, chromosome 17 at 13,062,980 bp (GRCm38)
  • A to G, chromosome 17 at 28,008,059 bp (GRCm38)
  • A to T, chromosome 17 at 36,460,619 bp (GRCm38)
  • A to G, chromosome 18 at 5,049,062 bp (GRCm38)
  • T to C, chromosome 18 at 14,799,178 bp (GRCm38)
  • T to C, chromosome 18 at 46,741,393 bp (GRCm38)
  • T to C, chromosome 18 at 82,405,787 bp (GRCm38)
  • A to G, chromosome 19 at 41,206,554 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9801 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
070046-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.