Strain Name:
Hairless-2
Stock Number:
037615-MU
Citation ID:
RRID:MMRRC_037615-MU
Major Collection:

Gene Information

Genotype Determination
ES Cell Line
N/A
Phenotype

Homozygous: adults are virtually nude except for vibrissae and sensitive hairs which exist as short stumps. Some individuals have normal shaped, but short vibrissae. The trait can be detected in newborn deer mice by the twisted appearance of the vibrissae. Animals begin to lose hair about twelve days of age, following a period during which the coat has a distinctive sheen. Juveniles have dark pigmented bodies with pink faces. Transient coats appear at subadult and adult molts. The deer mice are most readily distinguished from hairless-1 by the absence of elongate claws. Scanning electromicroscopy reveals many hairs that are abnormally twisted or bilobar, and that are fragile and readily break off at the skin surface. Ears of homozygous hairless-2 deer mice are abnormally thin and there is a general reduction in body weight.

Heterozygous: hairless-2 deer mice have full pelage, but the coat has a greasy texture.

MeSH Terms
    Primary Reference

    For more information, please see Hairless-2 on the Peromyscus Genetic Stock Center website.

    Colony and Husbandry Information

    Colony Surveillance Program and Current Health Reports

    Mice derived from requested cell lines via Microinjection services will be pathogen tested prior to delivery of mice and health reports will be provided. If you require additional health status information prior to requesting microinjection please email mmrrc@missouri.edu.
    Coat Color
    Homozygous (hr-2/hr-2) have no hair except for very short vibrissae and claws tend to elongate.

    Heterozygous (hr-2/+) are the same as wild-type.

    MMRRC Breeding System
    Not applicable; only cryopreserved sperm is available. The parent colony was sufficiently large to use a random breeding scheme
    Breeding Scheme(s)
    Not applicable; only cryopreserved sperm is available; mice cryorecovered (see below) can be bred Wild-type female x Wild-type male
    Overall Breeding Performance
    Peromyscus mice breed best in a 16:8 light / dark cycle.
    Average litter size
    4.4
    Recommended wean age
    25 days

    Order Request Information

    Male mice were obtained from the Peromyscus Genetic Stock Center as part of a long term project to develop cropreservation techniques for Peromyscus. Sperm have been cryopreserved and are available. However, cryorecovery techniques have yet to be developed.

    Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

    - Products for this strain are Not Yet Available for Ordering
    - If you register interest in this strain, you will be notified when it becomes available for ordering.

    To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.