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Strain Name:
C57BL/6J-MtgxR0012Btlr/Mmmh
Stock Number:
038307-MU
Citation ID:
RRID:MMRRC_038307-MU
Other Names:
R0012 (G1), C57BL/6J-MtgxR0012Btlr
Major Collection:

Strain Information

Fasl
Name: Fas ligand
Synonyms: Fas-L, CD178, APT1LG1, CD95L, Tnfsf6, Fasl
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14103
Homologene: 533
Gpd2
Name: glycerol phosphate dehydrogenase 2, mitochondrial
Synonyms: Gdm1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14571
HGNC: HGNC:4456
Homologene: 352
Nos1
Name: nitric oxide synthase 1, neuronal
Synonyms: nNOS, bNOS, Nos-1, NO, 2310005C01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18125
HGNC: HGNC:7872
Homologene: 37327
Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Get3
Name: guided entry of tail-anchored proteins factor 3, ATPase
Synonyms: ArsA, 1810048H22Rik, Asna1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 56495
HGNC: HGNC:752
Homologene: 31513
Orc1
Name: origin recognition complex, subunit 1
Synonyms: MmORC1, Orc1l
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18392
HGNC: HGNC:8487
Homologene: 31221
Tnpo3
Name: transportin 3
Synonyms: 5730544L10Rik, C430013M08Rik, D6Ertd313e
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 320938
Homologene: 40848
Map3k4
Name: mitogen-activated protein kinase kinase kinase 4
Synonyms: MTK1, MAPKKK4, D17Rp17, RP17, D17Rp17e, Mekk4, T-associated sex reversal, Tas
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 26407
VEGA: 17
HGNC: HGNC:6856
Homologene: 31346
Suclg1
Name: succinate-CoA ligase, GDP-forming, alpha subunit
Synonyms: Sucla1, 1500000I01Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56451
Homologene: 55785
Snrnp200
Name: small nuclear ribonucleoprotein 200 (U5)
Synonyms: U5-200KD, HELIC2, A330064G03Rik, Ascc3l1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 320632
Homologene: 5859
Fdft1
Name: farnesyl diphosphate farnesyl transferase 1
Synonyms: squalene synthase, SQS, Ss
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 14137
VEGA: 14
HGNC: HGNC:3629
Homologene: 3281
Copb1
Name: coatomer protein complex, subunit beta 1
Synonyms: Copb1, 2610019B04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 70349
HGNC: HGNC:2231
Homologene: 5664
Brwd1
Name: bromodomain and WD repeat domain containing 1
Synonyms: 5330419I02Rik, D530019K20Rik, G1-403-16, Wdr9, repro5
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 93871
Homologene: 23130
Arap2
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Synonyms: Centd1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 212285
Homologene: 9064
Tet2
Name: tet methylcytosine dioxygenase 2
Synonyms: E130014J05Rik, Ayu17-449
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 214133
Homologene: 49498
Bnip3
Name: BCL2/adenovirus E1B interacting protein 3
Synonyms: Nip3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12176
HGNC: HGNC:1084
Homologene: 2990
Cacul1
Name: CDK2 associated, cullin domain 1
Synonyms: 2810417M16Rik, D130033C15Rik, 9830127L17Rik, 2700078E11Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 78832
VEGA: 19
Homologene: 17821
Trp53bp2
Name: transformation related protein 53 binding protein 2
Synonyms: ASPP2, 53BP2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 209456
Homologene: 3959
Plekhg5
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 5
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 269608
Homologene: 10768
Zfp35
Name: zinc finger protein 35
Synonyms: Zfp-35
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 22694
Homologene: 133081
C2cd3
Name: C2 calcium-dependent domain containing 3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 277939
Homologene: 19524
Mrgpra1
Name: MAS-related GPR, member A1
Synonyms: MrgA1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233221
Homologene: 79615
Cic
Name: capicua transcriptional repressor
Synonyms: 1200010B10Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71722
Homologene: 87637
Chrna10
Name: cholinergic receptor, nicotinic, alpha polypeptide 10
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 504186
Homologene: 56886
Chd2
Name: chromodomain helicase DNA binding protein 2
Synonyms: 2810040A01Rik, 2810013C04Rik, 5630401D06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244059
HGNC: HGNC:1917
Homologene: 37462
Tjp1
Name: tight junction protein 1
Synonyms: ZO-1, ZO1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 21872
Homologene: 2445
Mob1b
Name: MOB kinase activator 1B
Synonyms: 1110003E08Rik, Mobkl1a
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 68473
Homologene: 61676
Adam33
Name: a disintegrin and metallopeptidase domain 33
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 110751
Homologene: 11881
Lypd4
Name: Ly6/Plaur domain containing 4
Synonyms: 4933400F01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232973
Homologene: 45458
Ms4a4c
Name: membrane-spanning 4-domains, subfamily A, member 4C
Synonyms: 5830413L19Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 64380
Homologene: 113790
Lifr
Name: LIF receptor alpha
Synonyms: soluble differentiation-stimulating factor receptor, A230075M04Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16880
VEGA: 15
HGNC: HGNC:6597
Homologene: 1735
Nectin2
Name: nectin cell adhesion molecule 2
Synonyms: MPH, nectin-2, Cd112, Pvs, Pvrl2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19294
HGNC: HGNC:9707
Homologene: 86092
Psmd2
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
Synonyms: TEG-190, Tex190, 9430095H01Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 21762
HGNC: HGNC:9559
Homologene: 2101
Zfp644
Name: zinc finger protein 644
Synonyms: 1110068L01Rik, BM-005, Zep-2, D5Ertd689e
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 52397
Homologene: 12971
Rae1
Name: ribonucleic acid export 1
Synonyms: MNRP41, MNRP, 41, D2Ertd342e
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66679
HGNC: HGNC:9828
Homologene: 2676
Clstn1
Name: calsyntenin 1
Synonyms: calsyntenin-1, Cst-1, 1810034E21Rik, alcadein alpha
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 65945
Homologene: 8814
Agtr1a
Name: angiotensin II receptor, type 1a
Synonyms: AT1a, Angtr-1a, Agtr-1a, AT1, Agtr1a, 1810074K20Rik, Agt1ar
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 11607
HGNC: HGNC:336
Homologene: 3556
Adap1
Name: ArfGAP with dual PH domains 1
Synonyms: 4930431P11Rik, centaurin alpha 1, Centa1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231821
Homologene: 55997
Dock2
Name: dedicator of cyto-kinesis 2
Synonyms: MBC, CED-5, Hch
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 94176
HGNC: HGNC:2988
Homologene: 37984
Mthfd2l
Name: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
Synonyms: C630010D07Rik, 1110019K23Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 665563
Homologene: 28295
Scd2
Name: stearoyl-Coenzyme A desaturase 2
Synonyms: Scd-2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 20250
VEGA: 19
Homologene: 136612
Fat2
Name: FAT atypical cadherin 2
Synonyms: LOC245827, mKIAA0811, Fath2, EMI2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Col5a3
Name: collagen, type V, alpha 3
Synonyms: Pro-alpha3(V)
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 53867
Homologene: 9253
Ogfrl1
Name: opioid growth factor receptor-like 1
Synonyms: 2210417C17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 70155
Homologene: 11595
Unc80
Name: unc-80, NALCN activator
Synonyms: C230061B10Rik, C030018G13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329178
Homologene: 122243
Gm2962
Name: predicted pseudogene 2962
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 100504052
Or6k14
Name: olfactory receptor family 6 subfamily K member 14
Synonyms: GA_x6K02T2P20D-21075927-21074980, MOR105-9, MOR105-7, Olfr427, MOR105-13_p, MOR105-8, GA_x6K02T2P20D-21063569-21062619, Olfr426
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 259162
Homologene: 133035
Or4f62
Name: olfactory receptor family 4 subfamily F member 62
Synonyms: GA_x6K02T2Q125-73202172-73203134, MOR245-16, Olfr1318
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258022
Homologene: 134079
Ralgapa2
Name: Ral GTPase activating protein, alpha subunit 2 (catalytic)
Synonyms: A230067G21Rik, RGC2, AS250
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241694
Homologene: 28131
Rab33b
Name: RAB33B, member RAS oncogene family
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 19338
Homologene: 9642
Gm10691
Name: predicted gene 10691
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Tbx15
Name: T-box 15
Synonyms: Tbx8, de, Tbx14
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 21384
Homologene: 7967
Hipk1
Name: homeodomain interacting protein kinase 1
Synonyms: Myak, 1110062K04Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 15257
Homologene: 56483
Cfap206
Name: cilia and flagella associated protein 206
Synonyms: 1700003M02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69329
Homologene: 18713
Clspn
Name: claspin
Synonyms: E130314M08Rik, C85083
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 269582
Homologene: 11138
Hmgb4
Name: high-mobility group box 4
Synonyms: 1700001F22Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69317
Homologene: 83321
Kif17
Name: kinesin family member 17
Synonyms: N-4 kinesin, 5930435E01Rik, Kif17b
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16559
Homologene: 5883
Gsap
Name: gamma-secretase activating protein
Synonyms: A530088I07Rik, Pion
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 212167
Homologene: 45504
Fbxo24
Name: F-box protein 24
Synonyms: Fbx24, 4933422D21Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71176
Homologene: 14131
Ints15
Name: integrator complex subunit 15
Synonyms: E130309D02Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231868
Homologene: 11445
Tmem209
Name: transmembrane protein 209
Synonyms: 2700094F01Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 72649
Homologene: 18021
Mgam
Name: maltase-glucoamylase
Synonyms: 6030407P20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232714
HGNC: HGNC:7043
Homologene: 130099
Add2
Name: adducin 2
Synonyms: 2900072M03Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 11519
HGNC: HGNC:244
Homologene: 1221
Trpm1
Name: transient receptor potential cation channel, subfamily M, member 1
Synonyms: Mlsn1, 4732499L03Rik, melastatin, LTRPC1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17364
HGNC: HGNC:7146
Homologene: 19940
Dpysl4
Name: dihydropyrimidinase-like 4
Synonyms: unc-33-like phosphoprotein 4, Ulip4, CRMP-3, Drp-4, DPY4, Crmp3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 26757
HGNC: HGNC:3016
Homologene: 4691
Ints10
Name: integrator complex subunit 10
Synonyms: 4921521J11Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 70885
Homologene: 10029
Ushbp1
Name: USH1 protein network component harmonin binding protein 1
Synonyms: MCC2, 2210404N08Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234395
Homologene: 12914
Swsap1
Name: SWIM type zinc finger 7 associated protein 1
Synonyms: 2310047B19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66962
VEGA: 9
Homologene: 18487
Plet1
Name: placenta expressed transcript 1
Synonyms: 0610037B23Rik, PLET1, 1600029D21Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 76509
Homologene: 49928
Gcnt3
Name: glucosaminyl (N-acetyl) transferase 3, mucin type
Synonyms: 2010013H22Rik, 2210021I22Rik, 2210401J11Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 72077
VEGA: 9
HGNC: HGNC:4205
Homologene: 20993
Celf5
Name: CUGBP, Elav-like family member 5
Synonyms: 4930565A21Rik, Brunol5
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 319586
Homologene: 75172
Myh8
Name: myosin, heavy polypeptide 8, skeletal muscle, perinatal
Synonyms: MyHC-pn, Myhs-p, Myhsp, 4832426G23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17885
HGNC: HGNC:7578
Homologene: 68256
Ttc32
Name: tetratricopeptide repeat domain 32
Synonyms: 1700013G20Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 75516
VEGA: 12
Homologene: 18991
Zfp429
Name: zinc finger protein 429
Synonyms: 2810487A22Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 72807
Homologene: 110878
Naip2
Name: NLR family, apoptosis inhibitory protein 2
Synonyms: Naip2, Naip-rs6, Birc1b
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17948
HGNC: HGNC:7634
Homologene: 136092
Sharpin
Name: SHANK-associated RH domain interacting protein
Synonyms: 0610041B22Rik, SIPL1, cpdm
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 106025
Homologene: 11918
Slc38a4
Name: solute carrier family 38, member 4
Synonyms: Ata3, 1700012A18Rik, 1110012E16Rik, SNAT4
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 69354
VEGA: 15
Homologene: 75077
Or2aj5
Name: olfactory receptor family 2 subfamily AJ member 5
Synonyms: GA_x54KRFPKG5P-16052703-16051765, MOR273-2, Olfr170
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 258959
Homologene: 128058
Eaf2
Name: ELL associated factor 2
Synonyms: Traits, Festa, U19, FESTA-S, FESTA-L
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 106389
Homologene: 10208
Vmn2r100
Name: vomeronasal 2, receptor 100
Synonyms: EG627537
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627537
Homologene: 129750
Wdr24
Name: WD repeat domain 24
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268933
Homologene: 6870
Cul9
Name: cullin 9
Synonyms: 1810035I07Rik, Parc
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 78309
Homologene: 56696
Or9i1
Name: olfactory receptor family 9 subfamily I member 1
Synonyms: GA_x6K02T2RE5P-4193992-4194942, MOR211-1, Olfr1502
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258793
Homologene: 17394
Cyp2c70
Name: cytochrome P450, family 2, subfamily c, polypeptide 70
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226105
Homologene: 120027
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 23,370,125 bp
  • T to C, chromosome 1 at 66,507,391 bp
  • T to C, chromosome 1 at 161,788,164 bp
  • T to A, chromosome 1 at 170,925,339 bp
  • T to G, chromosome 1 at 174,100,207 bp
  • T to A, chromosome 1 at 182,444,718 bp
  • T to A, chromosome 2 at 57,338,868 bp
  • A to T, chromosome 2 at 112,156,826 bp
  • T to C, chromosome 2 at 127,228,549 bp
  • A to T, chromosome 2 at 131,052,920 bp
  • A to G, chromosome 2 at 146,412,752 bp
  • T to A, chromosome 2 at 173,002,673 bp
  • G to T, chromosome 3 at 51,484,316 bp
  • A to G, chromosome 3 at 95,308,095 bp
  • A to G, chromosome 3 at 99,352,096 bp
  • A to G, chromosome 3 at 103,763,680 bp
  • T to C, chromosome 3 at 133,476,558 bp
  • C to A, chromosome 4 at 34,714,519 bp
  • T to C, chromosome 4 at 108,595,646 bp
  • T to A, chromosome 4 at 126,564,929 bp
  • T to A, chromosome 4 at 128,260,725 bp
  • T to G, chromosome 4 at 138,293,748 bp
  • G to A, chromosome 4 at 149,634,796 bp
  • C to A, chromosome 4 at 152,104,750 bp
  • T to A, chromosome 5 at 21,226,229 bp
  • G to A, chromosome 5 at 62,683,484 bp
  • G to A, chromosome 5 at 88,756,084 bp
  • A to T, chromosome 5 at 90,961,383 bp
  • T to G, chromosome 5 at 106,635,043 bp
  • A to C, chromosome 5 at 117,893,902 bp
  • A to G, chromosome 5 at 137,621,994 bp
  • A to G, chromosome 5 at 139,307,734 bp
  • A to G, chromosome 5 at 143,314,182 bp
  • T to C, chromosome 6 at 29,589,177 bp
  • G to T, chromosome 6 at 30,502,113 bp
  • T to A, chromosome 6 at 40,765,256 bp
  • A to G, chromosome 6 at 73,270,997 bp
  • T to A, chromosome 6 at 86,098,628 bp
  • T to C, chromosome 7 at 19,730,744 bp
  • A to G, chromosome 7 at 24,865,332 bp
  • T to A, chromosome 7 at 25,287,140 bp
  • C to A, chromosome 7 at 25,287,141 bp
  • A to G, chromosome 7 at 47,335,470 bp
  • A to G, chromosome 7 at 64,268,591 bp
  • A to G, chromosome 7 at 65,329,775 bp
  • G to T, chromosome 7 at 73,455,519 bp
  • G to A, chromosome 7 at 100,418,522 bp
  • T to C, chromosome 7 at 102,115,057 bp
  • T to A, chromosome 7 at 114,237,408 bp
  • A to G, chromosome 7 at 138,898,672 bp
  • T to G, chromosome 7 at 139,097,883 bp
  • C to A, chromosome 8 at 68,807,475 bp
  • T to C, chromosome 8 at 71,395,040 bp
  • T to C, chromosome 8 at 85,025,096 bp
  • A to T, chromosome 9 at 20,777,108 bp
  • T to C, chromosome 9 at 21,957,022 bp
  • A to G, chromosome 9 at 50,499,130 bp
  • T to C, chromosome 9 at 70,034,085 bp
  • C to A, chromosome 10 at 81,469,512 bp
  • T to C, chromosome 11 at 34,783,795 bp
  • A to G, chromosome 11 at 55,262,871 bp
  • T to C, chromosome 11 at 67,300,021 bp
  • A to G, chromosome 12 at 9,035,897 bp
  • A to G, chromosome 13 at 13,687,694 bp
  • A to T, chromosome 13 at 30,381,749 bp
  • G to A, chromosome 13 at 67,390,677 bp
  • G to A, chromosome 13 at 100,155,029 bp
  • T to C, chromosome 14 at 63,177,698 bp
  • C to A, chromosome 15 at 7,175,608 bp
  • G to T, chromosome 15 at 76,348,343 bp
  • C to T, chromosome 15 at 96,999,629 bp
  • T to C, chromosome 16 at 19,606,440 bp
  • T to A, chromosome 16 at 20,661,684 bp
  • T to A, chromosome 16 at 36,808,174 bp
  • A to C, chromosome 16 at 96,059,652 bp
  • A to G, chromosome 17 at 12,238,189 bp
  • A to G, chromosome 17 at 19,504,874 bp
  • A to T, chromosome 17 at 19,526,034 bp
  • G to A, chromosome 17 at 25,827,113 bp
  • G to A, chromosome 17 at 46,538,510 bp
  • T to A, chromosome 18 at 24,002,944 bp
  • C to A, chromosome 19 at 11,418,980 bp
  • C to A, chromosome 19 at 13,861,823 bp
  • A to T, chromosome 19 at 40,187,243 bp
  • G to A, chromosome 19 at 44,301,246 bp
  • A to G, chromosome 19 at 60,564,253 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0012 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038307-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.