Strain Name:
C57BL/6J-MtgxR0024Btlr/Mmmh
Stock Number:
038319-MU
Citation ID:
RRID:MMRRC_038319-MU
Other Names:
R0024 (G1), C57BL/6J-MtgxR0024Btlr
Major Collection:

Gene Information

Utrn
Name: utrophin
Synonyms: G-utrophin, DRP, Dmdl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 22288
VEGA: 10
Homologene: 21398
Dst
Name: dystonin
Synonyms: A830042E19Rik, 2310001O04Rik, Macf2, bullous pemphigoid antigen 1, BPAG1-n, BPAG1, athetoid, Bpag, ah, bullous pemphigoid antigen 1, Bpag1, nmf339, nmf203
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Iqgap1
Name: IQ motif containing GTPase activating protein 1
Synonyms: D7Ertd237e, D7Ertd257e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 29875
HGNC: HGNC:6110
Homologene: 74514
St5
Name: suppression of tumorigenicity 5
Synonyms: 2010004M01Rik, 2610305K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 76954
Homologene: 3951
Btbd11
Name: BTB (POZ) domain containing 11
Synonyms: 6330404E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 74007
Homologene: 72536
Bbx
Name: bobby sox HMG box containing
Synonyms: 5530401J07Rik, 5730403O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 70508
Homologene: 10634
Prkd2
Name: protein kinase D2
Synonyms: PKD2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 101540
Homologene: 9516
Ttc27
Name: tetratricopeptide repeat domain 27
Synonyms: 2610511O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 74196
VEGA: 17
Homologene: 41191
Kif13b
Name: kinesin family member 13B
Synonyms: 5330429L19Rik, N-3 kinesin, GAKIN, C130021D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 16554
VEGA: 14
Homologene: 9073
Fry
Name: FRY microtubule binding protein
Synonyms: 9330186A19Rik, cg003
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 320365
Homologene: 113770
Ahctf1
Name: AT hook containing transcription factor 1
Synonyms: 6230412P20Rik, Elys
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226747
Homologene: 9142
Pi4ka
Name: phosphatidylinositol 4-kinase alpha
Synonyms: Pik4ca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224020
HGNC: HGNC:8983
Homologene: 11171
Atf7ip
Name: activating transcription factor 7 interacting protein
Synonyms: ATFa-associated Modulator, 2610204M12Rik, Mcaf1, AM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 54343
Homologene: 10051
Picalm
Name: phosphatidylinositol binding clathrin assembly protein
Synonyms: fit1, fit-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233489
Homologene: 111783
Sin3a
Name: transcriptional regulator, SIN3A (yeast)
Synonyms: mSin3A, Sin3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20466
Homologene: 32124
Grid2ip
Name: glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1
Synonyms: delphilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 170935
Homologene: 15781
Prpf31
Name: pre-mRNA processing factor 31
Synonyms: 1500019O16Rik, 2810404O06Rik, RP11, PRP31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 68988
Homologene: 5980
Rgs5
Name: regulator of G-protein signaling 5
Synonyms: 1110070A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 19737
Homologene: 2682
Slc6a3
Name: solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
Synonyms: DAT, Dat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 13162
VEGA: 13
Homologene: 55547
Tpm3
Name: tropomyosin 3, gamma
Synonyms: Tm5NM, Tpm5, Trop-5, Tpm-5, hTMnm, hTM30nm, gamma-TM, skalphaTM.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 59069
Homologene: 81889
Eif2ak3
Name: eukaryotic translation initiation factor 2 alpha kinase 3
Synonyms: PERK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 13666
HGNC: HGNC:3255
Homologene: 3557
Adgre5
Name: adhesion G protein-coupled receptor E5
Synonyms: Cd97, EGF-TM7 receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 26364
HGNC: HGNC:1711
Homologene: 8050
Ssh2
Name: slingshot protein phosphatase 2
Synonyms: SSH-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237860
Homologene: 14116
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 269700
Homologene: 28297
Plxna2
Name: plexin A2
Synonyms: 2810428A13Rik, PlexA2, Plxn2, OCT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18845
HGNC: HGNC:9100
Homologene: 56427
Abca16
Name: ATP-binding cassette, sub-family A (ABC1), member 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233810
Homologene: 132942
Myof
Name: myoferlin
Synonyms: E030042N20Rik, Fer1l3, 2310051D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226101
VEGA: 19
HGNC: HGNC:3656
Homologene: 40882
Sycp2l
Name: synaptonemal complex protein 2-like
Synonyms: LOC218175, Gm40956, EG621792
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 637277
Homologene: 52882
P3h3
Name: prolyl 3-hydroxylase 3
Synonyms: Grcb, Leprel2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 14789
Homologene: 8401
Gls2
Name: glutaminase 2 (liver, mitochondrial)
Synonyms: A330074B06Rik, Lga
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216456
Homologene: 40861
Ptpro
Name: protein tyrosine phosphatase, receptor type, O
Synonyms: D28, PTP-U2, GLEPP1, PTP-oc, PTPROt, Ptpn15, PTP-phi, PTP-BK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 19277
HGNC: HGNC:9678
Homologene: 21564
Astn1
Name: astrotactin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 11899
HGNC: HGNC:773
Homologene: 7233
Plcb1
Name: phospholipase C, beta 1
Synonyms: 3110043I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18795
Homologene: 22876
Gm14340
Name: predicted gene 14340
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
Camk2d
Name: calcium/calmodulin-dependent protein kinase II, delta
Synonyms: 8030469K03Rik, 2810011D23Rik, CaMK II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 108058
HGNC: HGNC:1462
Homologene: 55561
Slc24a2
Name: solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
Synonyms: 6330417K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 76376
Homologene: 10669
Rsc1a1
Name: regulatory solute carrier protein, family 1, member 1
Synonyms: OTTMUSG00000010365, mRS1, RS1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 69994
Homologene: 130554
Hfm1
Name: HFM1, ATP-dependent DNA helicase homolog
Synonyms: A330009G12Rik, LOC381663, Sec63d1, Mer3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 330149
Homologene: 87103
Olfr457
Name: olfactory receptor 457
Synonyms: MOR257-1, GA_x6K02T2P3E9-5088893-5089834
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 258989
Homologene: 133701
Cadm4
Name: cell adhesion molecule 4
Synonyms: Necl-4, Tsll2, SynCAM 4, Igsf4c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 260299
Homologene: 17063
Dll3
Name: delta like canonical Notch ligand 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 13389
HGNC: HGNC:2909
Homologene: 7291
Lysmd4
Name: LysM, putative peptidoglycan-binding, domain containing 4
Synonyms: 4930506D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 75099
Homologene: 45123
Arnt2
Name: aryl hydrocarbon receptor nuclear translocator 2
Synonyms: bHLHe1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11864
Homologene: 7230
Akip1
Name: A kinase (PRKA) interacting protein 1
Synonyms: ICRFP703B1614Q5.6, D930014E17Rik, ORF27, ICRFP703N2430Q5.6, BCA3, D7H11orf17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 57373
HGNC: HGNC:1170
Homologene: 10765
Aqp8
Name: aquaporin 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11833
HGNC: HGNC:642
Homologene: 68166
Gm9457
Name: predicted gene 9457
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 669393
Homologene: 131643
Ankrd34c
Name: ankyrin repeat domain 34C
Synonyms: B230218L05Rik, LOC330998
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 330998
Homologene: 19814
Gstt4
Name: glutathione S-transferase, theta 4
Synonyms: 4930583C14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 75886
Homologene: 57104
Emid1
Name: EMI domain containing 1
Synonyms: Emu1, CO-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 140703
Homologene: 135639
Krt34
Name: keratin 34
Synonyms: Krt1-4, 4733401E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16672
HGNC: HGNC:6452
Homologene: 31083
Entpd5
Name: ectonucleoside triphosphate diphosphohydrolase 5
Synonyms: mNTPase, NTPDase-5, Cd39l4, Pcph, ER-UDPase, NTPDase5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 12499
HGNC: HGNC:3367
Homologene: 37457
Sugct
Name: succinyl-CoA glutarate-CoA transferase
Synonyms: 5033411D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 192136
VEGA: 13
Homologene: 11681
Chdh
Name: choline dehydrogenase
Synonyms: D630034H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 218865
Homologene: 41261
Mroh2b
Name: maestro heat-like repeat family member 2B
Synonyms: 4930455B06Rik, Heatr7b2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223825
VEGA: 15
Homologene: 128807
Krt6a
Name: keratin 6A
Synonyms: MK6a, mK6[a], Krt2-6a, Krt2-6c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 16687
VEGA: 15
Homologene: 136794
Dscam
Name: DS cell adhesion molecule
Synonyms: 4932410A21Rik, Down syndrome cell adhesion molecule
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 13508
HGNC: HGNC:3039
Homologene: 74393
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 34,189,119 bp
  • G to A, chromosome 1 at 158,684,215 bp
  • T to A, chromosome 1 at 169,676,892 bp
  • G to A, chromosome 1 at 179,752,436 bp
  • T to A, chromosome 1 at 194,643,995 bp
  • A to G, chromosome 2 at 135,362,425 bp
  • T to A, chromosome 2 at 180,824,250 bp
  • C to A, chromosome 3 at 90,087,449 bp
  • A to G, chromosome 3 at 126,797,723 bp
  • T to C, chromosome 4 at 87,028,240 bp
  • T to C, chromosome 4 at 141,685,272 bp
  • T to C, chromosome 5 at 106,856,924 bp
  • C to T, chromosome 5 at 121,308,576 bp
  • T to A, chromosome 5 at 143,391,041 bp
  • T to G, chromosome 5 at 150,380,803 bp
  • A to G, chromosome 6 at 42,471,260 bp
  • A to G, chromosome 6 at 70,892,356 bp
  • T to C, chromosome 6 at 124,857,458 bp
  • T to C, chromosome 6 at 136,599,820 bp
  • T to A, chromosome 6 at 137,443,594 bp
  • C to A, chromosome 7 at 3,636,659 bp
  • T to C, chromosome 7 at 16,847,643 bp
  • T to C, chromosome 7 at 24,502,744 bp
  • A to G, chromosome 7 at 28,300,161 bp
  • A to G, chromosome 7 at 67,226,080 bp
  • T to C, chromosome 7 at 80,751,939 bp
  • A to G, chromosome 7 at 84,284,126 bp
  • T to C, chromosome 7 at 90,130,704 bp
  • T to C, chromosome 7 at 109,524,659 bp
  • T to C, chromosome 7 at 109,704,138 bp
  • A to T, chromosome 7 at 120,433,385 bp
  • T to C, chromosome 7 at 123,467,440 bp
  • A to C, chromosome 8 at 4,813,131 bp
  • T to C, chromosome 8 at 83,728,284 bp
  • T to A, chromosome 9 at 57,118,253 bp
  • G to A, chromosome 9 at 89,729,527 bp
  • A to G, chromosome 10 at 12,406,011 bp
  • T to A, chromosome 10 at 75,817,204 bp
  • A to G, chromosome 10 at 85,387,447 bp
  • G to A, chromosome 10 at 128,199,256 bp
  • A to T, chromosome 11 at 5,143,869 bp
  • A to T, chromosome 11 at 77,454,966 bp
  • A to T, chromosome 11 at 100,041,037 bp
  • T to C, chromosome 12 at 84,373,733 bp
  • G to A, chromosome 13 at 16,857,869 bp
  • A to G, chromosome 13 at 41,141,788 bp
  • A to T, chromosome 13 at 73,540,837 bp
  • G to A, chromosome 14 at 30,031,596 bp
  • A to G, chromosome 14 at 64,750,273 bp
  • T to A, chromosome 15 at 4,925,627 bp
  • A to G, chromosome 15 at 101,690,715 bp
  • T to C, chromosome 16 at 17,315,535 bp
  • T to A, chromosome 16 at 50,224,918 bp
  • G to A, chromosome 16 at 96,593,385 bp
  • T to C, chromosome 17 at 74,770,264 bp
  • G to T, chromosome 19 at 37,915,740 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0024 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038319-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.