Strain Name:
C57BL/6J-MtgxR0042Btlr/Mmmh
Stock Number:
038336-MU
Citation ID:
RRID:MMRRC_038336-MU
Other Names:
R0042 (G1), C57BL/6J-MtgxR0042Btlr
Major Collection:

Gene Information

Ank2
Name: ankyrin 2, brain
Synonyms: ankyrin B, Gm4392, Ank-2, Ankyrin-2, Ankyrin-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 109676
HGNC: HGNC:493
Eya1
Name: EYA transcriptional coactivator and phosphatase 1
Synonyms: bor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14048
HGNC: HGNC:3519
Homologene: 74943
Atl3
Name: atlastin GTPase 3
Synonyms: 5730596K20Rik, 4633402C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 109168
VEGA: 19
Homologene: 9149
Prex2
Name: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
Synonyms: C030045D06Rik, Depdc2, 6230420N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 109294
Homologene: 23523
Atr
Name: ataxia telangiectasia and Rad3 related
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 245000
HGNC: HGNC:882
Homologene: 96916
Ccnb2
Name: cyclin B2
Synonyms: CycB2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12442
VEGA: 9
HGNC: HGNC:1580
Homologene: 74359
Metap1
Name: methionyl aminopeptidase 1
Synonyms: 1700029C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 75624
Homologene: 6488
Grb10
Name: growth factor receptor bound protein 10
Synonyms: 5730571D09Rik, Meg1, maternally expressed gene 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14783
HGNC: HGNC:4564
Homologene: 3882
Dmxl1
Name: Dmx-like 1
Synonyms: C630007L23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240283
HGNC: HGNC:2937
Homologene: 21136
Utp18
Name: UTP18 small subunit processome component
Synonyms: 6230425C22Rik, Wdr50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217109
Homologene: 41087
Abca1
Name: ATP-binding cassette, sub-family A (ABC1), member 1
Synonyms: ABC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11303
HGNC: HGNC:29
Homologene: 21130
Mib2
Name: mindbomb E3 ubiquitin protein ligase 2
Synonyms: Zzank1, 2210008I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 76580
Homologene: 16062
Thbs1
Name: thrombospondin 1
Synonyms: TSP1, Thbs-1, TSP-1, tbsp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 21825
Homologene: 31142
Ptger1
Name: prostaglandin E receptor 1 (subtype EP1)
Synonyms: EP1, 42kDa, Ptgerep1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 19216
HGNC: HGNC:9593
Homologene: 738
Itgb3
Name: integrin beta 3
Synonyms: CD61, platelet glycoprotein IIIa (GP3A)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16416
HGNC: HGNC:6156
Homologene: 55444
Fam120a
Name: family with sequence similarity 120, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218236
VEGA: 13
Homologene: 8752
Enpp3
Name: ectonucleotide pyrophosphatase/phosphodiesterase 3
Synonyms: CD203c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 209558
VEGA: 10
HGNC: HGNC:3358
Homologene: 3683
Vps11
Name: VPS11, CORVET/HOPS core subunit
Synonyms: 1200011A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71732
VEGA: 9
Homologene: 6673
Adgrf3
Name: adhesion G protein-coupled receptor F3
Synonyms: PGR23, LOC381628, Gpr113
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381628
Homologene: 17826
P4hb
Name: prolyl 4-hydroxylase, beta polypeptide
Synonyms: PDI, ERp59, protein disulfide isomerase, Pdia1, Thbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18453
HGNC: HGNC:8548
Homologene: 55495
Rbl1
Name: RB transcriptional corepressor like 1
Synonyms: retinoblastoma-like 1 (p107), p107
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19650
HGNC: HGNC:9893
Homologene: 2172
Stk32b
Name: serine/threonine kinase 32B
Synonyms: YANK2, Stk32, 2510009F08Rik, STKG6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 64293
Homologene: 48654
Acr
Name: acrosin prepropeptide
Synonyms: preproacrosin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 11434
VEGA: 15
HGNC: HGNC:126
Homologene: 855
Cib1
Name: calcium and integrin binding 1 (calmyrin)
Synonyms: Kip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 23991
Homologene: 4654
Rdh10
Name: retinol dehydrogenase 10 (all-trans)
Synonyms: 4921506A21Rik, 3110069K09Rik, m366Asp, D1Ertd762e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98711
Homologene: 14061
Svep1
Name: sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Synonyms: D430029O09Rik, 1110021D17Rik, 4833413O10Rik, Polydom
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 64817
Homologene: 23386
Tnr
Name: tenascin R
Synonyms: TN-R, J1-tenascin, janusin, restrictin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 21960
Homologene: 124416
Olfr1251
Name: olfactory receptor 1251
Synonyms: MOR231-24_p, GA_x6K02T2Q125-51109312-51108356, MOR231-15P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 259145
Homologene: 74065
Mroh4
Name: maestro heat-like repeat family member 4
Synonyms: 1700016M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 69439
Homologene: 72545
Slc13a5
Name: solute carrier family 13 (sodium-dependent citrate transporter), member 5
Synonyms: Indy, mINDY, Nact, NaC2/NaCT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237831
Homologene: 21941
Lgsn
Name: lengsin, lens protein with glutamine synthetase domain
Synonyms: Lgs, lengsin, Gluld1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 266744
Homologene: 9569
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: OTTMUSG00000005786, LOC380698
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380698
Homologene: 70869
Vsig8
Name: V-set and immunoglobulin domain containing 8
Synonyms: EG240916
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240916
Homologene: 18616
Olfr1097
Name: olfactory receptor 1097
Synonyms: GA_x6K02T2Q125-48376288-48375341, MOR206-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258840
Homologene: 37005
Adad1
Name: adenosine deaminase domain containing 1 (testis specific)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 21744
Homologene: 7569
Tmod4
Name: tropomodulin 4
Synonyms: skeletal tropomodulin, Sk-Tmod, MTMOD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 50874
Homologene: 8355
Hspb7
Name: heat shock protein family, member 7 (cardiovascular)
Synonyms: Hsp25-2, cvHsp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 29818
HGNC: HGNC:5249
Homologene: 8480
Alox5ap
Name: arachidonate 5-lipoxygenase activating protein
Synonyms: Flap, arachidonate 5 lipoxygenase activating protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11690
HGNC: HGNC:436
Homologene: 1231
Il17ra
Name: interleukin 17 receptor A
Synonyms: VDw217, Il17r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16172
HGNC: HGNC:5985
Homologene: 7378
Rgs9bp
Name: regulator of G-protein signalling 9 binding protein
Synonyms: R9AP, Rgs9-1bp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243923
Homologene: 17113
Helt
Name: helt bHLH transcription factor
Synonyms: megane, Heslike
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234219
Homologene: 18357
Olfr860
Name: olfactory receptor 860
Synonyms: GA_x6K02T2PVTD-13586614-13585661, MOR146-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258521
Homologene: 134093
Col6a6
Name: collagen, type VI, alpha 6
Synonyms: E330026B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 245026
Homologene: 18260
Taar6
Name: trace amine-associated receptor 6
Synonyms: LOC215855
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215855
Homologene: 27874
Gzmm
Name: granzyme M (lymphocyte met-ase 1)
Synonyms: Lmet1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16904
HGNC: HGNC:4712
Homologene: 21099
Inhbc
Name: inhibin beta-C
Synonyms: activin beta-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16325
VEGA: 10
HGNC: HGNC:6068
Homologene: 21142
Gpr179
Name: G protein-coupled receptor 179
Synonyms: 5330439C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217143
Homologene: 34917
Prpsap1
Name: phosphoribosyl pyrophosphate synthetase-associated protein 1
Synonyms: PAP39, 5730409F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67763
HGNC: HGNC:9466
Homologene: 55687
Npas3
Name: neuronal PAS domain protein 3
Synonyms: 4930423H22Rik, bHLHe12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 27386
VEGA: 12
Homologene: 8461
4930458L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Ttc23l
Name: tetratricopeptide repeat domain 23-like
Synonyms: 4930401A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 75777
Homologene: 44907
Cdh12
Name: cadherin 12
Synonyms: Br-cadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 215654
HGNC: HGNC:1751
Homologene: 37873
Krt4
Name: keratin 4
Synonyms: Krt-2.4, K4, Krt2-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16682
VEGA: 15
HGNC: HGNC:6441
Homologene: 20523
Hrg
Name: histidine-rich glycoprotein
Synonyms: D18020, D16JH2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 94175
HGNC: HGNC:5181
Homologene: 137650
Vmn2r102
Name: vomeronasal 2, receptor 102
Synonyms: EG224572
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224572
Homologene: 115024
A930017K11Rik
Name: RIKEN cDNA A930017K11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 100034748
H2-Q3
Name: histocompatibility 2, Q region locus 3
Synonyms: Qa3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 625285
Ttc39d
Name: tetratricopeptide repeat domain 39D
Synonyms: 4930560E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 67737
Homologene: 65053
Jakmip2
Name: janus kinase and microtubule interacting protein 2
Synonyms: 6430702L21Rik, D930046L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 76217
VEGA: 18
Homologene: 8866
Dym
Name: dymeclin
Synonyms: 1810041M12Rik, 4933427L07Rik, C030019K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 69190
VEGA: 18
Homologene: 69237
Plcb3
Name: phospholipase C, beta 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18797
VEGA: 19
HGNC: HGNC:9056
Homologene: 47960
Vwce
Name: von Willebrand factor C and EGF domains
Synonyms: 1300015B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 71768
VEGA: 19
Homologene: 17651
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 11,080,081 bp
  • T to C, chromosome 1 at 14,184,489 bp
  • T to C, chromosome 1 at 16,108,036 bp
  • C to T, chromosome 1 at 31,190,453 bp
  • A to T, chromosome 1 at 159,887,025 bp
  • T to C, chromosome 1 at 172,560,358 bp
  • A to G, chromosome 2 at 86,890,491 bp
  • A to C, chromosome 2 at 89,667,454 bp
  • A to C, chromosome 2 at 118,122,877 bp
  • A to G, chromosome 2 at 157,175,704 bp
  • T to C, chromosome 3 at 37,083,173 bp
  • T to C, chromosome 3 at 95,129,788 bp
  • T to C, chromosome 3 at 126,936,631 bp
  • C to T, chromosome 3 at 138,472,157 bp
  • C to T, chromosome 4 at 53,059,245 bp
  • T to C, chromosome 4 at 58,123,192 bp
  • A to G, chromosome 4 at 141,423,934 bp
  • A to T, chromosome 4 at 155,659,440 bp
  • A to G, chromosome 5 at 30,197,428 bp
  • A to C, chromosome 5 at 37,716,748 bp
  • T to C, chromosome 5 at 149,279,259 bp
  • T to C, chromosome 6 at 120,472,125 bp
  • C to A, chromosome 7 at 35,585,033 bp
  • C to T, chromosome 7 at 80,230,378 bp
  • T to C, chromosome 8 at 46,292,396 bp
  • G to T, chromosome 8 at 83,668,166 bp
  • A to G, chromosome 9 at 19,845,779 bp
  • G to T, chromosome 9 at 44,356,291 bp
  • A to G, chromosome 9 at 70,419,053 bp
  • T to A, chromosome 9 at 95,927,356 bp
  • T to C, chromosome 9 at 105,780,697 bp
  • T to C, chromosome 10 at 23,985,123 bp
  • A to C, chromosome 10 at 24,774,824 bp
  • T to C, chromosome 10 at 79,694,565 bp
  • A to G, chromosome 10 at 127,357,433 bp
  • G to T, chromosome 11 at 11,936,798 bp
  • A to G, chromosome 11 at 59,052,585 bp
  • A to T, chromosome 11 at 72,259,114 bp
  • G to T, chromosome 11 at 93,875,858 bp
  • C to T, chromosome 11 at 97,334,931 bp
  • A to G, chromosome 11 at 104,667,140 bp
  • T to A, chromosome 11 at 116,479,656 bp
  • G to A, chromosome 11 at 120,568,266 bp
  • T to A, chromosome 12 at 54,048,841 bp
  • A to G, chromosome 13 at 48,934,014 bp
  • A to T, chromosome 13 at 64,922,563 bp
  • A to C, chromosome 15 at 10,551,541 bp
  • A to C, chromosome 15 at 21,537,677 bp
  • T to A, chromosome 15 at 74,610,305 bp
  • T to A, chromosome 15 at 89,574,332 bp
  • T to G, chromosome 15 at 101,922,752 bp
  • A to T, chromosome 16 at 22,961,136 bp
  • C to A, chromosome 17 at 19,660,589 bp
  • C to A, chromosome 17 at 25,947,982 bp
  • A to G, chromosome 17 at 35,359,847 bp
  • T to C, chromosome 17 at 80,215,950 bp
  • T to G, chromosome 18 at 43,552,145 bp
  • C to A, chromosome 18 at 49,864,035 bp
  • T to C, chromosome 18 at 75,125,539 bp
  • T to C, chromosome 19 at 6,966,420 bp
  • T to G, chromosome 19 at 7,529,023 bp
  • C to T, chromosome 19 at 10,646,813 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0042 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038336-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.