Strain Name:
C57BL/6J-MtgxR0056Btlr/Mmmh
Stock Number:
038350-MU
Citation ID:
RRID:MMRRC_038350-MU
Other Names:
R0056 (G1), C57BL/6J-MtgxR0056Btlr
Major Collection:

Gene Information

Camkk2
Name: calcium/calmodulin-dependent protein kinase kinase 2, beta
Synonyms: 6330570N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 207565
HGNC: HGNC:1470
Homologene: 32756
Satb1
Name: special AT-rich sequence binding protein 1
Synonyms: 2610306G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20230
Homologene: 2232
Pelp1
Name: proline, glutamic acid and leucine rich protein 1
Synonyms: 4930563C04Rik, MNAR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 75273
Homologene: 8664
Wdr59
Name: WD repeat domain 59
Synonyms: 5430401O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 319481
Homologene: 38685
Emc8
Name: ER membrane protein complex subunit 8
Synonyms: Noc4, Fam158b, Cox4nb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 18117
HGNC: HGNC:7864
Homologene: 4424
Chd9
Name: chromodomain helicase DNA binding protein 9
Synonyms: 1810014J18Rik, AD013, A330063D19Rik, 9030205D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 109151
Homologene: 11844
Bms1
Name: BMS1, ribosome biogenesis factor
Synonyms: Bms1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 213895
Homologene: 7065
G3bp1
Name: GTPase activating protein (SH3 domain) binding protein 1
Synonyms: GAP SH3 binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 27041
Homologene: 38096
Epb41l3
Name: erythrocyte membrane protein band 4.1 like 3
Synonyms: NBL3, 4.1B, DAL1P, Epb4.1l3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13823
HGNC: HGNC:3380
Homologene: 49308
Atp9b
Name: ATPase, class II, type 9B
Synonyms: IIb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 50771
VEGA: 18
Homologene: 21915
Snapc1
Name: small nuclear RNA activating complex, polypeptide 1
Synonyms: 2700033G17Rik, 9630050P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 75627
VEGA: 12
Homologene: 2317
Marf1
Name: meiosis regulator and mRNA stability 1
Synonyms: 4921513D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 223989
VEGA: 16
Homologene: 40967
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Son
Name: Son DNA binding protein
Synonyms: 2900011L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 20658
Homologene: 10551
Ticam2
Name: toll-like receptor adaptor molecule 2
Synonyms: TRAM, Tirp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225471
Homologene: 11014
Sos1
Name: SOS Ras/Rac guanine nucleotide exchange factor 1
Synonyms: 4430401P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20662
VEGA: 17
Homologene: 4117
Polr2b
Name: polymerase (RNA) II (DNA directed) polypeptide B
Synonyms: RPB2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231329
HGNC: HGNC:9188
Homologene: 722
Lama5
Name: laminin, alpha 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16776
HGNC: HGNC:6485
Homologene: 4060
Etv6
Name: ets variant 6
Synonyms: Tel, translocation-ets-leukemia
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14011
HGNC: HGNC:3495
Homologene: 37560
Gpihbp1
Name: GPI-anchored HDL-binding protein 1
Synonyms: GPI-HBP1, 1110002J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 68453
Homologene: 136164
Htt
Name: huntingtin
Synonyms: huntingtin, HD, htt, IT15, C430023I11Rik, Hdh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 15194
HGNC: HGNC:4851
Homologene: 1593
Ncoa2
Name: nuclear receptor coactivator 2
Synonyms: TIF2/GRIP-1, Grip1, D1Ertd433e, glucocorticoid receptor-interacting protein 1, TIF2, TIF-2, SRC-2, KAT13C, bHLHe75
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17978
HGNC: HGNC:7669
Homologene: 4768
Mapk6
Name: mitogen-activated protein kinase 6
Synonyms: Prkm6, ERK3, Prkm4, Erk3, Mapk63, Mapk4, D130053K17Rik, 2610021I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 50772
HGNC: HGNC:6879
Homologene: 55683
Nupl1
Name: nucleoporin like 1
Synonyms: 1700017F11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71844
VEGA: 14
Homologene: 40924
Marchf6
Name: membrane associated ring-CH-type finger 6
Synonyms: F830029L24Rik, March6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223455
VEGA: 15
Homologene: 4301
Robo4
Name: roundabout guidance receptor 4
Synonyms: 1200012D01Rik, Magic roundabout
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74144
Homologene: 10397
Kcng3
Name: potassium voltage-gated channel, subfamily G, member 3
Synonyms: KV6.3, Kv10.1b, Kv10.1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 225030
VEGA: 17
Homologene: 15168
Nobox
Name: NOBOX oogenesis homeobox
Synonyms: Og2x
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 18291
Homologene: 51066
Gdf11
Name: growth differentiation factor 11
Synonyms: Bmp11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14561
HGNC: HGNC:4216
Homologene: 21183
Tex15
Name: testis expressed gene 15
Synonyms: 2210014E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 104271
Homologene: 12837
Stk10
Name: serine/threonine kinase 10
Synonyms: Lok, Gek1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20868
Homologene: 38122
Plpp2
Name: phospholipid phosphatase 2
Synonyms: Lpp2, Ppap2c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 50784
HGNC: HGNC:9230
Homologene: 2752
Chd3
Name: chromodomain helicase DNA binding protein 3
Synonyms: Mi-2 alpha, Prp9-1, Prp7, 2600010P09Rik, Chd7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216848
HGNC: HGNC:1918
Homologene: 62693
Trpm1
Name: transient receptor potential cation channel, subfamily M, member 1
Synonyms: Mlsn1, 4732499L03Rik, melastatin, LTRPC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17364
HGNC: HGNC:7146
Homologene: 19940
Tnfaip3
Name: tumor necrosis factor, alpha-induced protein 3
Synonyms: A20, zinc finger protein A20, Tnfip3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 21929
Homologene: 4582
Snx25
Name: sorting nexin 25
Synonyms: LOC382008, SBBI31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102141
Homologene: 23744
H1f8
Name: H1.8 linker histone
Synonyms: H1oo, H1foo, H1-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171506
Homologene: 51377
Mogat1
Name: monoacylglycerol O-acyltransferase 1
Synonyms: 0610030A14Rik, mDC2, MGAT1, Dgat2l1, 1110064N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68393
Homologene: 105237
Ccdc121
Name: coiled-coil domain containing 121
Synonyms: LOC329308, 6530421E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 403180
Homologene: 136217
Lyplal1
Name: lysophospholipase-like 1
Synonyms: Q96AVO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226791
Homologene: 13683
Traf6
Name: TNF receptor-associated factor 6
Synonyms: 2310003F17Rik, C630032O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22034
Homologene: 3395
Bche
Name: butyrylcholinesterase
Synonyms: C730038G20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12038
HGNC: HGNC:983
Homologene: 20065
Etv3
Name: ets variant 3
Synonyms: ETS-domain transcriptional repressor, METS, Pe1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 27049
HGNC: HGNC:3492
Homologene: 21085
Pglyrp3
Name: peptidoglycan recognition protein 3
Synonyms: LOC242100
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242100
Homologene: 71559
Lamtor3
Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Synonyms: MEK binding partner 1, Mp1, Map2k1ip1, Mapksp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56692
Homologene: 10539
Myo1h
Name: myosin 1H
Synonyms: 4631401O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231646
Homologene: 82639
Klrd1
Name: killer cell lectin-like receptor, subfamily D, member 1
Synonyms: CD94
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16643
HGNC: HGNC:6378
Homologene: 1705
Klk7
Name: kallikrein related-peptidase 7 (chymotryptic, stratum corneum)
Synonyms: Prss6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 23993
HGNC: HGNC:6368
Homologene: 37998
Olfr684
Name: olfactory receptor 684
Synonyms: GA_x6K02T2PBJ9-7786441-7785503, MOR40-8P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244187
Homologene: 133596
Otoa
Name: otoancorin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 246190
Homologene: 71803
Adam34l
Name: a disintegrin and metallopeptidase domain 34 like
Synonyms: Gm5346
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 384813
Homologene: 78104
Iqcm
Name: IQ motif containing M
Synonyms: 1700007B14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 71831
Homologene: 53050
C630050I24Rik
Name: RIKEN cDNA C630050I24 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Pold2
Name: polymerase (DNA directed), delta 2, regulatory subunit
Synonyms: p50, po1D2, 50kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18972
HGNC: HGNC:9176
Homologene: 4538
4932411E22Rik
Name: RIKEN cDNA 4932411E22 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Fscb
Name: fibrous sheath CABYR binding protein
Synonyms: EG623046
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 623046
VEGA: 12
Homologene: 136275
Morc2b
Name: microrchidia 2B
Synonyms: 4932411A10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 240069
Homologene: 18615
Fshr
Name: follicle stimulating hormone receptor
Synonyms: follicle-stimulating hormone receptor, Follitropin receptor, FSH-R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14309
VEGA: 17
HGNC: HGNC:3969
Homologene: 117
Entpd7
Name: ectonucleoside triphosphate diphosphohydrolase 7
Synonyms: LALP1, 2810003F23Rik, 1810020C02Rik, 1810012B13Rik, Lysal2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 93685
Homologene: 122202
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to G, chromosome 1 at 78,523,770 bp
  • C to A, chromosome 1 at 117,516,497 bp
  • T to C, chromosome 1 at 181,510,553 bp
  • G to A, chromosome 1 at 186,088,566 bp
  • A to G, chromosome 2 at 101,697,151 bp
  • A to T, chromosome 2 at 180,187,106 bp
  • A to T, chromosome 3 at 73,701,321 bp
  • T to C, chromosome 3 at 87,535,828 bp
  • G to T, chromosome 3 at 92,025,804 bp
  • T to A, chromosome 3 at 137,926,950 bp
  • T to C, chromosome 5 at 34,826,078 bp
  • T to C, chromosome 5 at 77,334,535 bp
  • C to T, chromosome 5 at 114,330,212 bp
  • C to T, chromosome 5 at 122,742,198 bp
  • A to G, chromosome 6 at 43,304,919 bp
  • G to T, chromosome 6 at 115,946,973 bp
  • A to T, chromosome 6 at 118,405,229 bp
  • G to A, chromosome 6 at 129,593,775 bp
  • G to T, chromosome 6 at 134,248,534 bp
  • T to C, chromosome 7 at 43,812,010 bp
  • A to G, chromosome 7 at 64,243,586 bp
  • A to G, chromosome 7 at 105,157,122 bp
  • A to G, chromosome 7 at 121,131,347 bp
  • A to G, chromosome 8 at 33,582,027 bp
  • A to T, chromosome 8 at 43,625,503 bp
  • A to T, chromosome 8 at 46,038,513 bp
  • A to G, chromosome 8 at 75,753,386 bp
  • A to G, chromosome 8 at 90,933,537 bp
  • G to T, chromosome 8 at 107,119,394 bp
  • C to T, chromosome 8 at 111,480,607 bp
  • A to G, chromosome 8 at 120,659,083 bp
  • G to A, chromosome 9 at 37,404,477 bp
  • A to G, chromosome 9 at 75,388,816 bp
  • A to T, chromosome 10 at 19,005,293 bp
  • A to G, chromosome 10 at 79,527,229 bp
  • C to T, chromosome 10 at 128,886,425 bp
  • T to A, chromosome 11 at 5,872,338 bp
  • T to A, chromosome 11 at 32,617,851 bp
  • A to G, chromosome 11 at 55,498,041 bp
  • G to A, chromosome 11 at 69,359,913 bp
  • A to T, chromosome 11 at 70,393,832 bp
  • A to G, chromosome 11 at 89,391,676 bp
  • T to G, chromosome 12 at 64,474,247 bp
  • C to T, chromosome 12 at 73,975,032 bp
  • T to A, chromosome 13 at 11,669,038 bp
  • A to G, chromosome 14 at 60,239,475 bp
  • T to C, chromosome 15 at 31,467,734 bp
  • T to A, chromosome 15 at 75,597,133 bp
  • C to T, chromosome 16 at 14,142,534 bp
  • T to C, chromosome 16 at 91,678,155 bp
  • T to A, chromosome 17 at 33,138,759 bp
  • T to A, chromosome 17 at 51,740,203 bp
  • A to T, chromosome 17 at 69,253,397 bp
  • A to T, chromosome 17 at 80,413,621 bp
  • A to G, chromosome 17 at 83,587,756 bp
  • T to G, chromosome 17 at 88,988,457 bp
  • G to T, chromosome 18 at 46,560,334 bp
  • A to G, chromosome 18 at 80,765,803 bp
  • T to A, chromosome 19 at 43,725,294 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0056 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038350-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.