Strain Name:
C57BL/6J-MtgxR0069Btlr/Mmmh
Stock Number:
038360-MU
Citation ID:
RRID:MMRRC_038360-MU
Other Names:
R0069 (G1), C57BL/6J-MtgxR0069Btlr
Major Collection:

Gene Information

Ebf2
Name: early B cell factor 2
Synonyms: O/E-3, Mmot1, D14Ggc1e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 13592
Homologene: 56471
Prpf6
Name: pre-mRNA splicing factor 6
Synonyms: 1190003A07Rik, ANT-1, 2610031L17Rik, U5-102K
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 68879
Homologene: 5368
Rad54l2
Name: RAD54 like 2 (S. cerevisiae)
Synonyms: G630026H09Rik, Srisnf2l, Arip4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 81000
Homologene: 56698
Creb1
Name: cAMP responsive element binding protein 1
Synonyms: 3526402H21Rik, 2310001E10Rik, Creb-1, Creb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12912
HGNC: HGNC:2345
Homologene: 3223
Map1b
Name: microtubule-associated protein 1B
Synonyms: Mtap5, Mtap-5, MAP5, Mtap1b, LC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 17755
VEGA: 13
HGNC: HGNC:6836
Homologene: 38111
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: slip, DNA-PK, DNAPDcs, dxnph, DOXNPH, DNA-PKcs, XRCC7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Xpnpep3
Name: X-prolyl aminopeptidase 3, mitochondrial
Synonyms: E430012M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 321003
Homologene: null
Nacc1
Name: nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
Synonyms: Nac1, Btbd14b, 4930511N13Rik, 2010001H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 66830
VEGA: 8
Homologene: 12042
Ints3
Name: integrator complex subunit 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229543
Homologene: 11309
Fam168a
Name: family with sequence similarity 168, member A
Synonyms: 2610030B18Rik, B930006L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 319604
Homologene: 18702
Nfx1
Name: nuclear transcription factor, X-box binding 1
Synonyms: 1300017N15Rik, 3000003M19Rik, Tex42, TEG-42
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 74164
HGNC: HGNC:7803
Homologene: 1875
Pole2
Name: polymerase (DNA directed), epsilon 2 (p59 subunit)
Synonyms: DNA polymerase epsilon small subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 18974
VEGA: 12
HGNC: HGNC:9178
Homologene: 2015
Slitrk6
Name: SLIT and NTRK-like family, member 6
Synonyms: 4832410J21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 239250
VEGA: 14
Homologene: 12986
Slc38a10
Name: solute carrier family 38, member 10
Synonyms: 1810073N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 72055
Homologene: 41556
Hk2
Name: hexokinase 2
Synonyms: HKII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 15277
HGNC: HGNC:4923
Homologene: 37273
Myo1d
Name: myosin ID
Synonyms: 9930104H07Rik, D11Ertd9e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 338367
HGNC: HGNC:7598
Homologene: 45576
Ptger1
Name: prostaglandin E receptor 1 (subtype EP1)
Synonyms: 42kDa, EP1, Ptgerep1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 19216
HGNC: HGNC:9593
Homologene: 738
Vps13d
Name: vacuolar protein sorting 13D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230895
Homologene: 15583
Zswim6
Name: zinc finger SWIM-type containing 6
Synonyms: 2900036G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 67263
VEGA: 13
Homologene: 83517
Prox1
Name: prospero homeobox 1
Synonyms: A230003G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 19130
HGNC: HGNC:9459
Homologene: 2069
Mpzl3
Name: myelin protein zero-like 3
Synonyms: ruf, A530065I17Rik, rc, 5430427F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 319742
Homologene: 18867
Ostm1
Name: osteopetrosis associated transmembrane protein 1
Synonyms: gl, HSPC019, 1200002H13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14628
Homologene: 32203
Ube2e3
Name: ubiquitin-conjugating enzyme E2E 3
Synonyms: ubcM2, Ubce4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22193
Homologene: 4636
Dctn2
Name: dynactin 2
Synonyms: C130077D06Rik, DCTN-50, 2310042E05Rik, p50, RBP50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 69654
VEGA: 10
HGNC: HGNC:2712
Homologene: 4667
Diablo
Name: diablo, IAP-binding mitochondrial protein
Synonyms: 1700006L01Rik, Smac, 0610041G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 66593
Homologene: 10532
Ppp2r5c
Name: protein phosphatase 2, regulatory subunit B', gamma
Synonyms: Band 8A, B56/PP2A gamma, 2700063L20Rik, 2610043M05Rik, D12Bwg0916e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 26931
VEGA: 12
HGNC: HGNC:9311
Homologene: 128665
Ryr1
Name: ryanodine receptor 1, skeletal muscle
Synonyms: skrr, Ryr, calcium release channel isoform 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20190
Homologene: 68069
Antxr2
Name: anthrax toxin receptor 2
Synonyms: CMG-2, cI-35, 2310046B19Rik, CMG2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71914
Homologene: 43236
Pip4p1
Name: phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1
Synonyms: Tmem55b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 219024
Homologene: 10279
Fbn2
Name: fibrillin 2
Synonyms: Sne, Fib-2, sy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 14119
VEGA: 18
HGNC: HGNC:3604
Homologene: 1515
Poteg
Name: POTE ankyrin domain family, member G
Synonyms: 4930456F22Rik, 4921537P18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 70952
HGNC: null
Homologene: 134158
A2ml1
Name: alpha-2-macroglobulin like 1
Synonyms: BC048546, Ovos2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232400
HGNC: null
Homologene: 45969
Slfn10-ps
Name: schlafen 10, pseudogene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237887
HGNC: null
Homologene: null
Olfr1335
Name: olfactory receptor 1335
Synonyms: GA_x6K02T2QD9B-18723799-18724749, MOR259-5, MOR259-12, GA_x6K02T2QD9B-18726774-18727577, Olfr1335, Olfr1334-ps1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 435804
HGNC: null
Homologene: 138635
Rnpepl1
Name: arginyl aminopeptidase (aminopeptidase B)-like 1
Synonyms: 1110014H17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 108657
Homologene: 36367
D2hgdh
Name: D-2-hydroxyglutarate dehydrogenase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 98314
Homologene: 5534
Ifi206
Name: interferon activated gene 206
Synonyms: Pyblhin-C, Gm4955
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 102639543
HGNC: HGNC:5395
Homologene: 115929
Cd101
Name: CD101 antigen
Synonyms: Igsf2, LOC381460
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 630146
HGNC: HGNC:5949
Homologene: 3142
Gne
Name: glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
Synonyms: 2310066H07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 50798
Homologene: 3996
Sult1e1
Name: sulfotransferase family 1E, member 1
Synonyms: Ste, EST
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20860
Homologene: 101388
Clec2g
Name: C-type lectin domain family 2, member g
Synonyms: Ocilrp1, 4632413B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 70809
HGNC: null
Homologene: 136309
Zfp329
Name: zinc finger protein 329
Synonyms: 4632409L22Rik, 2810439M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67230
Homologene: 23459
Pde8a
Name: phosphodiesterase 8A
Synonyms: Pde8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18584
HGNC: HGNC:8793
Homologene: 1957
Itgal
Name: integrin alpha L
Synonyms: Cd11a, LFA-1, Ly-21, Ly-15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 16408
HGNC: HGNC:6148
Homologene: 1666
Myom2
Name: myomesin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 17930
HGNC: HGNC:7614
Homologene: 2953
Olfr952
Name: olfactory receptor 952
Synonyms: GA_x6K02T2PVTD-33124064-33123120, MOR171-21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235248
VEGA: 9
HGNC: null
Homologene: 133698
Mei4
Name: meiotic double-stranded break formation protein 4
Synonyms: 4930486G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 75033
Homologene: 87251
Tcrg-V7
Name: T cell receptor gamma, variable 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 21641
HGNC: null
Homologene: null
Vmn1r208
Name: vomeronasal 1 receptor 208
Synonyms: Vmn1r208-ps, V1rh9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 171252
HGNC: null
Homologene: 110880
Ccnb1ip1
Name: cyclin B1 interacting protein 1
Synonyms: mei4, Hei10, LOC239083
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 239083
VEGA: 14
Homologene: 18819
Lzts3
Name: leucine zipper, putative tumor suppressor family member 3
Synonyms: Prosapip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241638
Homologene: 8824
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 64,576,208 bp
  • T to A, chromosome 1 at 92,918,898 bp
  • G to T, chromosome 1 at 93,835,287 bp
  • A to T, chromosome 1 at 173,486,847 bp
  • A to G, chromosome 1 at 190,160,919 bp
  • C to A, chromosome 2 at 78,919,949 bp
  • T to A, chromosome 2 at 130,636,540 bp
  • T to A, chromosome 2 at 181,615,963 bp
  • A to G, chromosome 3 at 90,400,647 bp
  • A to G, chromosome 3 at 101,008,217 bp
  • T to C, chromosome 4 at 40,986,688 bp
  • A to C, chromosome 4 at 44,060,099 bp
  • A to T, chromosome 4 at 118,809,690 bp
  • A to G, chromosome 4 at 145,062,563 bp
  • A to T, chromosome 5 at 87,579,897 bp
  • T to A, chromosome 5 at 97,948,250 bp
  • A to T, chromosome 5 at 123,518,024 bp
  • A to G, chromosome 6 at 82,736,528 bp
  • A to T, chromosome 6 at 128,561,562 bp
  • T to A, chromosome 6 at 128,948,753 bp
  • T to C, chromosome 6 at 128,980,311 bp
  • A to T, chromosome 7 at 12,810,932 bp
  • A to C, chromosome 7 at 29,110,505 bp
  • T to C, chromosome 7 at 81,319,123 bp
  • C to T, chromosome 7 at 100,835,411 bp
  • A to G, chromosome 7 at 127,310,331 bp
  • A to G, chromosome 8 at 15,117,624 bp
  • T to C, chromosome 8 at 27,447,821 bp
  • A to T, chromosome 8 at 83,668,319 bp
  • T to A, chromosome 8 at 84,677,199 bp
  • A to G, chromosome 9 at 39,426,892 bp
  • T to C, chromosome 9 at 45,068,252 bp
  • C to T, chromosome 9 at 82,025,582 bp
  • C to A, chromosome 9 at 106,710,365 bp
  • A to C, chromosome 10 at 42,692,956 bp
  • A to T, chromosome 10 at 127,277,485 bp
  • A to G, chromosome 11 at 80,637,953 bp
  • A to G, chromosome 11 at 83,035,542 bp
  • A to T, chromosome 11 at 120,106,502 bp
  • A to T, chromosome 12 at 69,209,887 bp
  • A to T, chromosome 12 at 110,567,770 bp
  • A to G, chromosome 13 at 19,178,422 bp
  • A to T, chromosome 13 at 22,772,425 bp
  • A to G, chromosome 13 at 99,429,848 bp
  • T to C, chromosome 13 at 107,738,563 bp
  • T to C, chromosome 14 at 50,929,163 bp
  • A to T, chromosome 14 at 67,410,050 bp
  • G to A, chromosome 14 at 81,519,382 bp
  • A to T, chromosome 14 at 110,749,932 bp
  • T to C, chromosome 15 at 81,430,798 bp
  • G to A, chromosome 16 at 15,726,504 bp
  • T to C, chromosome 18 at 58,069,184 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0069 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038360-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.