Strain Name:
C57BL/6J-MtgxR0082Btlr/Mmmh
Stock Number:
038369-MU
Citation ID:
RRID:MMRRC_038369-MU
Other Names:
R0082 (G1), C57BL/6J-MtgxR0082Btlr
Major Collection:

Gene Information

Kcmf1
Name: potassium channel modulatory factor 1
Synonyms: clone DEBT-91, 1700094M07Rik, Pmcf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74287
Homologene: 99845
Prrc2b
Name: proline-rich coiled-coil 2B
Synonyms: Bat2l, 5830434P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227723
Homologene: 106649
Sgsm1
Name: small G protein signaling modulator 1
Synonyms: Rutbc2, 2410098H20Rik, D5Bwg1524e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 52850
Homologene: 64485
Gpr139
Name: G protein-coupled receptor 139
Synonyms: LOC209776, GPRg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 209776
Homologene: 45860
Srek1
Name: splicing regulatory glutamine/lysine-rich protein 1
Synonyms: Sfrs12, AL118220, SRrp508, SRrp86
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218543
Homologene: 10581
Cep57
Name: centrosomal protein 57
Synonyms: 4921510P06Rik, 4931428M20Rik, Tsp57, 3110002L15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74360
Homologene: 8790
Utp6
Name: UTP6 small subunit processome component
Synonyms: 4732497O03Rik, HCA66
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216987
Homologene: 41265
Dync1h1
Name: dynein cytoplasmic 1 heavy chain 1
Synonyms: MAP1C, Dnchc1, dynein heavy chain, retrograde transport, 9930018I23Rik, Dnec1, Loa, Swl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13424
HGNC: HGNC:2961
Homologene: 1053
Mmp20
Name: matrix metallopeptidase 20 (enamelysin)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 30800
VEGA: 9
HGNC: HGNC:7167
Homologene: 21001
Galnt5
Name: polypeptide N-acetylgalactosaminyltransferase 5
Synonyms: ppGaNTase-T5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241391
HGNC: HGNC:4127
Homologene: 8733
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: LOC381341, Dnahc7, Dnahc7a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 627872
Homologene: 41287
Adcy1
Name: adenylate cyclase 1
Synonyms: D11Bwg1392e, I-AC, AC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 432530
HGNC: HGNC:232
Homologene: 41419
Sp2
Name: Sp2 transcription factor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 78912
Homologene: 2340
Arhgef1
Name: Rho guanine nucleotide exchange factor (GEF) 1
Synonyms: Lsc, Lbcl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16801
HGNC: HGNC:681
Homologene: 3454
Vip
Name: vasoactive intestinal polypeptide
Synonyms: PHI, peptide histidine isoleucine
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22353
VEGA: 10
Homologene: 2539
Adam17
Name: a disintegrin and metallopeptidase domain 17
Synonyms: CD156b, Tace
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 11491
HGNC: HGNC:195
Homologene: 2395
Synrg
Name: synergin, gamma
Synonyms: L71-5, Ap1gbp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217030
HGNC: HGNC:557
Homologene: 105680
Prkrip1
Name: Prkr interacting protein 1 (IL11 inducible)
Synonyms: C114, 8430424D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 66801
Homologene: 6323
Ppip5k2
Name: diphosphoinositol pentakisphosphate kinase 2
Synonyms: Cfap160, Hisppd1, Vip2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227399
Homologene: 49409
Zfp445
Name: zinc finger protein 445
Synonyms: ZNF168
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235682
VEGA: 9
Homologene: 27832
Hpse
Name: heparanase
Synonyms: Hpa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 15442
HGNC: HGNC:5164
Homologene: 68528
Cdh23
Name: cadherin 23 (otocadherin)
Synonyms: nmf252, bob, sals, mdfw, ahl, nmf181, USH1D, 4930542A03Rik, nmf112
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22295
Homologene: 11142
Spdye4b
Name: speedy/RINGO cell cycle regulator family, member E4B
Synonyms: 4933411G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 330228
Homologene: 138445
Pigg
Name: phosphatidylinositol glycan anchor biosynthesis, class G
Synonyms: Gpi7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 433931
Homologene: 39421
Ahrr
Name: aryl-hydrocarbon receptor repressor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 11624
HGNC: HGNC:346
Homologene: 49215
Glt6d1
Name: glycosyltransferase 6 domain containing 1
Synonyms: 4933411C14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71103
Homologene: 18826
Polq
Name: polymerase (DNA directed), theta
Synonyms: A430110D14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 77782
HGNC: HGNC:9186
Homologene: 32727
Ankrd33b
Name: ankyrin repeat domain 33B
Synonyms: 0610012A05Rik, 3021401C12Rik, 5730557B15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 67434
Homologene: 12362
Ccdc180
Name: coiled-coil domain containing 180
Synonyms: LOC381522, E230008N13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381522
Homologene: 117988
Lrrc46
Name: leucine rich repeat containing 46
Synonyms: 1700006D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69297
Homologene: 12307
Slc8b1
Name: solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
Synonyms: NCLX, Slc24a6, NCKX6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 170756
Homologene: 41602
Tie1
Name: tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Synonyms: D430008P04Rik, tie-1, TIE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21846
Homologene: 3957
Wdr91
Name: WD repeat domain 91
Synonyms: 9530020G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 101240
Homologene: 8562
4833427G06Rik
Name: RIKEN cDNA 4833427G06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235345
VEGA: 9
Homologene: 52243
Col6a5
Name: collagen, type VI, alpha 5
Synonyms: Col6a5, Gm7455
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 665033
Homologene: 122792
Pomgnt2
Name: protein O-linked mannose beta 1,4-N-acetylglucosaminyltransferase 2
Synonyms: C85492, Gtdc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 215494
VEGA: 9
Homologene: 32795
Olfr786
Name: olfactory receptor 786
Synonyms: GA_x6K02T2PULF-11116958-11117896, MOR111-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258542
HGNC: HGNC:8355
Homologene: 133582
Olfr799
Name: olfactory receptor 799
Synonyms: GA_x6K02T2PULF-11325750-11326685, MOR114-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258929
Homologene: 37000
Fam173a
Name: family with sequence similarity 173, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 214917
VEGA: 17
Homologene: 11398
Sfi1
Name: Sfi1 homolog, spindle assembly associated (yeast)
Synonyms: 2310047I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 78887
Homologene: 12707
Cdh4
Name: cadherin 4
Synonyms: R-cadherin, R-Cadh, Rcad
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12561
HGNC: HGNC:1763
Homologene: 48044
Rpl9
Name: ribosomal protein L9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20005
Homologene: 90855
Klra8
Name: killer cell lectin-like receptor, subfamily A, member 8
Synonyms: Ly49u129, Cmv1, Ly49h, Cmv-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16639
Homologene: 110821
Klra2
Name: killer cell lectin-like receptor, subfamily A, member 2
Synonyms: Ly49b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16633
Homologene: 133782
Olfr591
Name: olfactory receptor 591
Synonyms: MOR24-1P, GA_x6K02T2PBJ9-5889409-5888465
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258139
Homologene: 79429
Qprt
Name: quinolinate phosphoribosyltransferase
Synonyms: QPRTase, nicotinate-nucleotide pyrophosphorylase, 2410027J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67375
HGNC: HGNC:9755
Homologene: 8623
Eef1akmt2
Name: EEF1A lysine methyltransferase 2
Synonyms: 2010208K18Rik, Mettl10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 72096
Homologene: 6175
Stox2
Name: storkhead box 2
Synonyms: 4933409N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 71069
Homologene: 18414
Slc38a7
Name: solute carrier family 38, member 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234595
Homologene: 41237
Rskr
Name: ribosomal protein S6 kinase related
Synonyms: BC030499
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216976
Homologene: 79669
Tmem97
Name: transmembrane protein 97
Synonyms: D11Bhm182e, 1810014L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69071
Homologene: 6443
Hoxb3
Name: homeobox B3
Synonyms: Hox-2.7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 15410
HGNC: HGNC:5114
Homologene: 1617
Wipi1
Name: WD repeat domain, phosphoinositide interacting 1
Synonyms: 4930533H01Rik, D11Ertd498e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 52639
Homologene: 117983
Evpl
Name: envoplakin
Synonyms: 210kDa protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14027
HGNC: HGNC:3503
Homologene: 1506
F13a1
Name: coagulation factor XIII, A1 subunit
Synonyms: Factor XIIIA, 1200014I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 74145
VEGA: 13
HGNC: HGNC:3531
Homologene: 20077
Ly86
Name: lymphocyte antigen 86
Synonyms: MD1, MD-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17084
VEGA: 13
Homologene: 48274
Olfr729
Name: olfactory receptor 729
Synonyms: GA_x6K02T2PMLR-5839874-5838903, MOR246-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258275
Homologene: 17167
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 53,518,708 bp
  • A to T, chromosome 1 at 97,759,332 bp
  • C to A, chromosome 2 at 25,794,727 bp
  • T to C, chromosome 2 at 32,212,298 bp
  • A to T, chromosome 2 at 57,999,035 bp
  • A to T, chromosome 2 at 179,894,188 bp
  • A to G, chromosome 4 at 45,896,205 bp
  • T to A, chromosome 4 at 118,484,353 bp
  • A to G, chromosome 5 at 65,388,652 bp
  • T to C, chromosome 5 at 100,692,262 bp
  • A to G, chromosome 5 at 108,312,885 bp
  • T to C, chromosome 5 at 113,288,836 bp
  • A to G, chromosome 5 at 120,524,200 bp
  • T to C, chromosome 5 at 136,197,828 bp
  • A to T, chromosome 5 at 143,195,675 bp
  • T to C, chromosome 6 at 34,906,685 bp
  • G to T, chromosome 6 at 72,850,487 bp
  • T to C, chromosome 6 at 130,125,055 bp
  • T to C, chromosome 6 at 131,220,247 bp
  • C to T, chromosome 7 at 24,912,605 bp
  • G to T, chromosome 7 at 103,173,202 bp
  • T to A, chromosome 7 at 119,145,045 bp
  • T to C, chromosome 7 at 127,108,186 bp
  • T to A, chromosome 7 at 132,851,472 bp
  • A to T, chromosome 8 at 47,203,282 bp
  • A to G, chromosome 8 at 95,840,481 bp
  • C to T, chromosome 9 at 7,642,807 bp
  • T to C, chromosome 9 at 13,810,876 bp
  • T to C, chromosome 9 at 51,101,802 bp
  • C to T, chromosome 9 at 105,889,335 bp
  • A to T, chromosome 9 at 121,982,260 bp
  • A to G, chromosome 9 at 122,852,356 bp
  • T to A, chromosome 10 at 5,644,953 bp
  • T to C, chromosome 10 at 60,312,587 bp
  • T to C, chromosome 10 at 129,437,271 bp
  • G to A, chromosome 10 at 129,647,653 bp
  • TCGC to TC, chromosome 11 at 3,146,254 bp
  • T to C, chromosome 11 at 7,149,497 bp
  • T to C, chromosome 11 at 78,293,558 bp
  • G to T, chromosome 11 at 78,542,588 bp
  • A to T, chromosome 11 at 79,953,631 bp
  • T to A, chromosome 11 at 83,987,910 bp
  • A to G, chromosome 11 at 96,344,271 bp
  • T to C, chromosome 11 at 96,961,699 bp
  • A to C, chromosome 11 at 97,041,077 bp
  • T to C, chromosome 11 at 109,578,284 bp
  • T to A, chromosome 11 at 116,235,003 bp
  • A to C, chromosome 12 at 21,329,048 bp
  • A to G, chromosome 12 at 110,636,446 bp
  • G to T, chromosome 13 at 36,988,953 bp
  • A to T, chromosome 13 at 37,418,537 bp
  • G to A, chromosome 13 at 74,283,024 bp
  • T to C, chromosome 13 at 103,743,686 bp
  • A to T, chromosome 14 at 50,148,055 bp
  • T to C, chromosome 15 at 31,297,789 bp
  • C to A, chromosome 16 at 37,017,257 bp
  • T to C, chromosome 17 at 25,791,574 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0082 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038369-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.