Strain Name:
C57BL/6J-MtgxR0113Btlr/Mmmh
Stock Number:
038399-MU
Citation ID:
RRID:MMRRC_038399-MU
Other Names:
R0113 (G1), C57BL/6J-MtgxR0113Btlr
Major Collection:

Gene Information

Satb1
Name: special AT-rich sequence binding protein 1
Synonyms: 2610306G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20230
Homologene: 2232
Eps8
Name: epidermal growth factor receptor pathway substrate 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 13860
HGNC: HGNC:3420
Homologene: 3272
Poli
Name: polymerase (DNA directed), iota
Synonyms: Rad30b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 26447
HGNC: HGNC:9182
Homologene: 5209
Ints1
Name: integrator complex subunit 1
Synonyms: 1110015K06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 68510
Homologene: 53111
Aspscr1
Name: alveolar soft part sarcoma chromosome region, candidate 1 (human)
Synonyms: ASPCR1, RCC17, ASPC, 1190006K01Rik, TUG, ASPL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68938
Homologene: 41550
Urb2
Name: URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 382038
Homologene: 8859
G3bp1
Name: GTPase activating protein (SH3 domain) binding protein 1
Synonyms: GAP SH3 binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 27041
Homologene: 38096
Cep170
Name: centrosomal protein 170
Synonyms: 4933426L22Rik, A330004A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 545389
Homologene: 22844
Zfp619
Name: zinc finger protein 619
Synonyms: 3000002G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 70227
Homologene: 133818
Nav2
Name: neuron navigator 2
Synonyms: POMFIL2, Unc53H2, HELAD1, RAINB2, 5330421F07Rik, Rainb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 78286
Homologene: 52330
Tbck
Name: TBC1 domain containing kinase
Synonyms: A630047E20Rik, C030007I09Rik, 1700120J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 271981
Homologene: 13221
Snapc1
Name: small nuclear RNA activating complex, polypeptide 1
Synonyms: 2700033G17Rik, 9630050P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 75627
VEGA: 12
Homologene: 2317
Marf1
Name: meiosis regulator and mRNA stability 1
Synonyms: 4921513D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 223989
VEGA: 16
Homologene: 40967
Dars
Name: aspartyl-tRNA synthetase
Synonyms: 5730439G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226414
HGNC: HGNC:2678
Homologene: 1032
Galnt5
Name: polypeptide N-acetylgalactosaminyltransferase 5
Synonyms: ppGaNTase-T5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241391
HGNC: HGNC:4127
Homologene: 8733
Ttc1
Name: tetratricopeptide repeat domain 1
Synonyms: TPR1, 4833412C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 66827
Homologene: 2485
Atcay
Name: ataxia, cerebellar, Cayman type
Synonyms: 3322401A10Rik, BNIP-H, ji
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16467
HGNC: HGNC:779
Homologene: 13206
Celf2
Name: CUGBP, Elav-like family member 2
Synonyms: Napor-2, ETR-3, B230345P09Rik, Cugbp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14007
HGNC: HGNC:2550
Homologene: 4783
Ino80
Name: INO80 complex subunit
Synonyms: 2310079N15Rik, INO80, 4632409L19Rik, Inoc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68142
Homologene: 75070
Atad2
Name: ATPase family, AAA domain containing 2
Synonyms: 2610509G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 70472
VEGA: 15
Homologene: 6044
Nupl1
Name: nucleoporin like 1
Synonyms: 1700017F11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71844
VEGA: 14
Homologene: 40924
Slain1
Name: SLAIN motif family, member 1
Synonyms: 9630044O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105439
Homologene: 16943
Phf21b
Name: PHD finger protein 21B
Synonyms: A730032D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 271305
Homologene: 78154
Kalrn
Name: kalirin, RhoGEF kinase
Synonyms: LOC224126, Hapip, 2210407G14Rik, E530005C20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 545156
HGNC: HGNC:4814
Homologene: 57160
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 94109
Homologene: 69536
Kcnk6
Name: potassium inwardly-rectifying channel, subfamily K, member 6
Synonyms: Toss, Twik2, D7Ertd764e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 52150
HGNC: HGNC:6281
Homologene: 31266
Scn4a
Name: sodium channel, voltage-gated, type IV, alpha
Synonyms: Nav1.4, mH2, SkM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 110880
Homologene: 283
Abca13
Name: ATP-binding cassette, sub-family A (ABC1), member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268379
Homologene: 27991
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: nesprin-2, syne-2, D12Ertd777e, 6820443O06Rik, Nesp2g, Cpfl8, diminished cone electroretinogram, dice
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319565
Homologene: 56700
Sec14l2
Name: SEC14-like lipid binding 2
Synonyms: 1300013M05Rik, tap, Spf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67815
Homologene: 8245
Zfp942
Name: zinc finger protein 942
Synonyms: 3110048L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 73233
Homologene: 133237
Arnt2
Name: aryl hydrocarbon receptor nuclear translocator 2
Synonyms: bHLHe1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11864
Homologene: 7230
Ces1f
Name: carboxylesterase 1F
Synonyms: TGH-2, CesML1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234564
HGNC: HGNC:1863
Homologene: 134311
Mfsd6
Name: major facilitator superfamily domain containing 6
Synonyms: 9630025I22Rik, MMR2, 2210010L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98682
Homologene: 9784
Ube2u
Name: ubiquitin-conjugating enzyme E2U (putative)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381534
Homologene: 17594
Ppp1r16a
Name: protein phosphatase 1, regulatory subunit 16A
Synonyms: 2900084E10Rik, Mypt3, R75527
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 73062
Homologene: 13161
Mfsd13a
Name: major facilitator superfamily domain containing 13a
Synonyms: 4930449A08Rik, 4930538D17Rik, Tmem180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 75146
Homologene: 12592
C4b
Name: complement component 4B (Chido blood group)
Synonyms: Ss, C4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12268
Homologene: 36030
Gm5155
Name: predicted gene 5155
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381852
Homologene: 115938
Yipf2
Name: Yip1 domain family, member 2
Synonyms: 1300010K09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74766
VEGA: 9
Homologene: 23430
Olfr50
Name: olfactory receptor 50
Synonyms: ID3, MOR136-6, GA_x6K02T2NLDC-33487752-33488690
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18350
Homologene: 74212
Gpr87
Name: G protein-coupled receptor 87
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 84111
HGNC: HGNC:4538
Homologene: 13021
1110012J17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Fam149a
Name: family with sequence similarity 149, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 212326
Homologene: 27540
Fcrla
Name: Fc receptor-like A
Synonyms: FCRL1, FREB, Freb1, Fcrx, mFREB, mFcrX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98752
Homologene: 13106
Chrna1
Name: cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
Synonyms: Achr-1, Acra
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11435
HGNC: HGNC:1955
Homologene: 59
D630003M21Rik
Name: RIKEN cDNA D630003M21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228846
Homologene: 18598
Usp13
Name: ubiquitin specific peptidase 13 (isopeptidase T-3)
Synonyms: IsoT-3, ISOT3, 2700071E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 72607
Homologene: 68372
Nwd2
Name: NACHT and WD repeat domain containing 2
Synonyms: B830017A01Rik, 3110047P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 319807
Homologene: 14974
Tmem132d
Name: transmembrane protein 132D
Synonyms: C630028F04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243274
Homologene: 71684
Cav1
Name: caveolin 1, caveolae protein
Synonyms: Cav-1, caveolin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12389
HGNC: HGNC:1527
Homologene: 1330
Trim28
Name: tripartite motif-containing 28
Synonyms: KRIP-1, KAP-1, Tif1b, MommeD9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 21849
Homologene: 21175
Psg23
Name: pregnancy-specific glycoprotein 23
Synonyms: 1620401C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56868
Homologene: 110989
3930402G23Rik
Name: RIKEN cDNA 3930402G23 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 665306
Brme1
Name: break repair meiotic recombinase recruitment factor 1
Synonyms: Meiok21, 4930432K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74666
Homologene: 11525
Olfr148
Name: olfactory receptor 148
Synonyms: M30, MOR224-4, GA_x6K02T2PVTD-33310486-33311418
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258498
VEGA: 9
Homologene: 128136
Edar
Name: ectodysplasin-A receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 13608
HGNC: HGNC:2895
Homologene: 7699
Nfic
Name: nuclear factor I/C
Synonyms: NF1-C, 1500041O16Rik, 1110019L22Rik, nuclear factor 1-C2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18029
HGNC: HGNC:7786
Homologene: 4088
Vmn1r216
Name: vomeronasal 1 receptor 216
Synonyms: V1ri10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 171279
Homologene: 110880
Dhrs1
Name: dehydrogenase/reductase (SDR family) member 1
Synonyms: 1110029G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 52585
Homologene: 41696
Zfp521
Name: zinc finger protein 521
Synonyms: B930086A16Rik, Evi3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225207
VEGA: 18
Homologene: 9151
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 52,709,189 bp
  • A to G, chromosome 1 at 128,368,456 bp
  • A to T, chromosome 1 at 170,922,299 bp
  • A to C, chromosome 1 at 176,758,455 bp
  • A to C, chromosome 2 at 6,624,714 bp
  • G to A, chromosome 2 at 36,793,994 bp
  • G to T, chromosome 2 at 36,793,995 bp
  • A to G, chromosome 2 at 57,998,877 bp
  • C to A, chromosome 2 at 73,566,836 bp
  • G to A, chromosome 2 at 119,382,960 bp
  • C to T, chromosome 2 at 158,196,575 bp
  • A to G, chromosome 3 at 32,817,876 bp
  • T to C, chromosome 3 at 59,179,511 bp
  • T to C, chromosome 3 at 132,743,080 bp
  • A to G, chromosome 4 at 100,481,655 bp
  • A to T, chromosome 5 at 63,807,898 bp
  • A to T, chromosome 5 at 127,784,593 bp
  • T to C, chromosome 5 at 139,765,213 bp
  • A to T, chromosome 6 at 17,308,049 bp
  • A to G, chromosome 6 at 137,537,684 bp
  • T to A, chromosome 7 at 13,028,701 bp
  • G to A, chromosome 7 at 17,908,948 bp
  • T to C, chromosome 7 at 18,612,002 bp
  • T to C, chromosome 7 at 29,232,209 bp
  • T to A, chromosome 7 at 39,537,759 bp
  • C to T, chromosome 7 at 49,535,953 bp
  • G to A, chromosome 7 at 84,347,530 bp
  • A to G, chromosome 8 at 10,926,126 bp
  • C to A, chromosome 8 at 15,984,849 bp
  • T to C, chromosome 8 at 45,341,024 bp
  • C to T, chromosome 8 at 84,167,242 bp
  • A to T, chromosome 8 at 93,279,699 bp
  • T to C, chromosome 8 at 124,030,926 bp
  • T to C, chromosome 9 at 21,590,116 bp
  • T to A, chromosome 9 at 39,614,002 bp
  • A to C, chromosome 10 at 58,629,449 bp
  • A to T, chromosome 10 at 81,214,720 bp
  • T to C, chromosome 10 at 81,420,585 bp
  • C to T, chromosome 11 at 4,103,661 bp
  • A to T, chromosome 11 at 9,292,114 bp
  • T to C, chromosome 11 at 43,745,288 bp
  • T to A, chromosome 11 at 55,495,426 bp
  • C to T, chromosome 11 at 106,345,436 bp
  • C to G, chromosome 11 at 120,688,925 bp
  • C to T, chromosome 12 at 73,975,032 bp
  • T to C, chromosome 12 at 75,930,578 bp
  • A to G, chromosome 12 at 76,033,722 bp
  • A to T, chromosome 13 at 23,099,461 bp
  • T to C, chromosome 14 at 55,739,939 bp
  • G to A, chromosome 14 at 60,251,291 bp
  • T to C, chromosome 14 at 103,685,825 bp
  • A to G, chromosome 15 at 58,120,934 bp
  • C to T, chromosome 15 at 76,690,799 bp
  • T to C, chromosome 15 at 84,804,767 bp
  • C to T, chromosome 16 at 14,142,534 bp
  • A to G, chromosome 16 at 34,049,936 bp
  • A to T, chromosome 17 at 21,929,085 bp
  • T to A, chromosome 17 at 34,741,240 bp
  • C to A, chromosome 17 at 51,782,698 bp
  • G to T, chromosome 17 at 66,354,242 bp
  • G to A, chromosome 18 at 13,845,091 bp
  • C to T, chromosome 18 at 70,528,758 bp
  • C to T, chromosome 19 at 46,366,504 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0113 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038399-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.