Strain Name:
C57BL/6J-MtgxR0134Btlr/Mmmh
Stock Number:
038419-MU
Citation ID:
RRID:MMRRC_038419-MU
Other Names:
R0134 (G1), C57BL/6J-MtgxR0134Btlr
Major Collection:

Gene Information

Smarca4
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Synonyms: SNF2beta, Brg1, SW1/SNF, b2b692Clo, b2b508.1Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20586
Homologene: 135927
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Acf7, Aclp7, trabeculin alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11426
Homologene: 136191
Lhx9
Name: LIM homeobox protein 9
Synonyms: LH2B, Lhx9 alpha, 3110009O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16876
Homologene: 7816
Smyd1
Name: SET and MYND domain containing 1
Synonyms: Bop, 4632404M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12180
Homologene: 7645
Ddx50
Name: DExD box helicase 50
Synonyms: GU2, RH-II/Gubeta, 4933429B04Rik, 8430408E17Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 94213
VEGA: 10
Homologene: 56986
Kif16b
Name: kinesin family member 16B
Synonyms: N-3 kinesin, 8430434E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16558
Homologene: 135708
Exoc4
Name: exocyst complex component 4
Synonyms: Sec8, Sec8l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 20336
Homologene: 40654
Btbd9
Name: BTB (POZ) domain containing 9
Synonyms: 1700023F20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224671
VEGA: 17
Homologene: 14995
Esyt2
Name: extended synaptotagmin-like protein 2
Synonyms: 2410017M09Rik, 4921504I16Rik, 2310058N22Rik, D12Ertd551e, Fam62b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 52635
VEGA: 12
Homologene: 32699
Slc10a7
Name: solute carrier family 10 (sodium/bile acid cotransporter family), member 7
Synonyms: 2410193C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 76775
Homologene: 81628
Bicd1
Name: BICD cargo adaptor 1
Synonyms: B830009D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12121
HGNC: HGNC:1049
Homologene: 37518
Il3
Name: interleukin 3
Synonyms: Il-3, PSF, MCGF, HCGF, BPA, Csfmu
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16187
HGNC: HGNC:6011
Homologene: 49243
Tep1
Name: telomerase associated protein 1
Synonyms: Tp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 21745
VEGA: 14
Homologene: 5157
Hdac2
Name: histone deacetylase 2
Synonyms: Yy1bp, D10Wsu179e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 15182
HGNC: HGNC:4853
Homologene: 68187
1110059E24Rik
Name: RIKEN cDNA 1110059E24 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66206
Homologene: 11933
Arhgap23
Name: Rho GTPase activating protein 23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 58996
Homologene: 104145
Vps13b
Name: vacuolar protein sorting 13B
Synonyms: 1810042B05Rik, Coh1, C330002D13Rik, 2310042E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 666173
VEGA: 15
HGNC: HGNC:2183
Homologene: 49516
Snrnp40
Name: small nuclear ribonucleoprotein 40 (U5)
Synonyms: 0610009C03Rik, Wdr57
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66585
Homologene: 3538
Tpd52l1
Name: tumor protein D52-like 1
Synonyms: D53
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 21987
VEGA: 10
Homologene: 2468
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: Ten-m3, 2610100B16Rik, Odz3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 23965
Homologene: 22673
Garnl3
Name: GTPase activating RANGAP domain-like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99326
Homologene: 13003
Siglecg
Name: sialic acid binding Ig-like lectin G
Synonyms: mSiglec-G, A630096C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243958
Homologene: 13228
Abca16
Name: ATP-binding cassette, sub-family A (ABC1), member 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233810
Homologene: 132942
Slc9a1
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 1
Synonyms: antiporter, Apnh, Nhe1, Nhe-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 20544
Homologene: 20660
Pdgfra
Name: platelet derived growth factor receptor, alpha polypeptide
Synonyms: CD140a, Pdgfr-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18595
HGNC: HGNC:8803
Homologene: 31361
Prickle1
Name: prickle planar cell polarity protein 1
Synonyms: 1110058P22Rik, mpk1, b2b019Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 106042
Homologene: 17686
Hes1
Name: hes family bHLH transcription factor 1
Synonyms: Hry, bHLHb39
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 15205
HGNC: HGNC:5192
Homologene: 38067
Itgae
Name: integrin alpha E, epithelial-associated
Synonyms: CD103, alpha-E1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16407
HGNC: HGNC:6147
Homologene: 113560
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Nlgn1
Name: neuroligin 1
Synonyms: 6330415N05Rik, NL1, Nlg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 192167
Homologene: 56690
Miox
Name: myo-inositol oxygenase
Synonyms: RSOR, 0610009I10Rik, C85427, Aldrl6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 56727
Homologene: 9732
AW549877
Name: expressed sequence AW549877
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 106064
VEGA: 15
Homologene: 27085
Siah2
Name: siah E3 ubiquitin protein ligase 2
Synonyms: Sinh2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20439
Homologene: 21053
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Nanos3
Name: nanos C2HC-type zinc finger 3
Synonyms: nos3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244551
Homologene: 65856
Pnp2
Name: purine-nucleoside phosphorylase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 667034
HGNC: HGNC:7892
Homologene: 227
Mndal
Name: myeloid nuclear differentiation antigen like
Synonyms: Ifi212
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 100040462
HGNC: HGNC:5395
Homologene: 115929
Nepn
Name: nephrocan
Synonyms: 5730521E12Rik, Npn, periolin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 66650
Homologene: 23549
Dnlz
Name: DNL-type zinc finger
Synonyms: 1110034G11Rik, D2Bwg1335e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 52838
Homologene: 36864
Olfr1055
Name: olfactory receptor 1055
Synonyms: GA_x6K02T2Q125-47819205-47818258, MOR186-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 259023
Homologene: 131140
Cd59b
Name: CD59b antigen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 333883
HGNC: HGNC:1689
Homologene: 56386
Rxfp1
Name: relaxin/insulin-like family peptide receptor 1
Synonyms: LOC381489, Lgr7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 381489
Homologene: 11007
Efcab14
Name: EF-hand calcium binding domain 14
Synonyms: 4732418C07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230648
Homologene: 8858
Plekhn1
Name: pleckstrin homology domain containing, family N member 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 231002
VEGA: 4
Homologene: 12949
Vmn2r13
Name: vomeronasal 2, receptor 13
Synonyms: Gm4867
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231589
Homologene: 129606
Zfp108
Name: zinc finger protein 108
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 54678
Homologene: 117959
Olfr307
Name: olfactory receptor 307
Synonyms: GA_x6K02T2NHDJ-9772012-9772953, MOR219-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258610
Kctd21
Name: potassium channel tetramerisation domain containing 21
Synonyms: EG622320
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 622320
Homologene: 54754
Tsfm
Name: Ts translation elongation factor, mitochondrial
Synonyms: 9430024O13Rik, EF-Tsmt, EF-TS, 2310050B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 66399
Homologene: 4184
Hps1
Name: HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
Synonyms: 6030422N11Rik, Hermansky-Pudlak syndrome 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 192236
HGNC: HGNC:5163
Homologene: 163
Map9
Name: microtubule-associated protein 9
Synonyms: 5033421J10Rik, 5330427D05Rik, ASAP, Mtap9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 213582
Homologene: 41591
Zfp518b
Name: zinc finger protein 518B
Synonyms: 6820424L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100515
Homologene: 19115
Ighv15-2
Name: immunoglobulin heavy variable V15-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 780864
Dele1
Name: DAP3 binding cell death enhancer 1
Synonyms: 0610009O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 66839
VEGA: 18
Homologene: 32232
Ptar1
Name: protein prenyltransferase alpha subunit repeat containing 1
Synonyms: 2010013L17Rik, 1700084D09Rik, 4930428J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 72351
VEGA: 19
Homologene: 34254
Lipo4
Name: lipase, member O4
Synonyms: Gm6857
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 628236
Homologene: 103863
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 138,838,679 bp
  • A to T, chromosome 1 at 173,857,513 bp
  • T to C, chromosome 2 at 26,351,368 bp
  • T to C, chromosome 2 at 33,006,804 bp
  • T to C, chromosome 2 at 40,596,983 bp
  • T to A, chromosome 2 at 76,710,124 bp
  • C to A, chromosome 2 at 76,793,130 bp
  • T to C, chromosome 2 at 86,347,728 bp
  • G to A, chromosome 2 at 104,078,941 bp
  • A to T, chromosome 2 at 142,672,375 bp
  • C to T, chromosome 3 at 25,435,925 bp
  • A to G, chromosome 3 at 58,676,115 bp
  • A to G, chromosome 3 at 79,657,476 bp
  • G to A, chromosome 3 at 82,359,983 bp
  • T to C, chromosome 4 at 115,740,531 bp
  • T to C, chromosome 4 at 123,432,843 bp
  • C to G, chromosome 4 at 130,378,043 bp
  • A to G, chromosome 4 at 133,420,605 bp
  • T to C, chromosome 4 at 156,228,243 bp
  • A to G, chromosome 5 at 38,674,659 bp
  • A to G, chromosome 5 at 75,166,511 bp
  • C to A, chromosome 5 at 109,175,049 bp
  • A to G, chromosome 6 at 33,971,946 bp
  • G to T, chromosome 6 at 71,216,765 bp
  • T to C, chromosome 6 at 149,512,950 bp
  • A to G, chromosome 7 at 24,260,467 bp
  • G to A, chromosome 7 at 43,411,171 bp
  • A to G, chromosome 7 at 86,335,595 bp
  • T to A, chromosome 7 at 97,348,091 bp
  • T to A, chromosome 7 at 120,540,155 bp
  • A to T, chromosome 8 at 48,674,472 bp
  • T to A, chromosome 8 at 78,697,158 bp
  • C to T, chromosome 8 at 84,176,134 bp
  • T to C, chromosome 9 at 21,637,324 bp
  • A to G, chromosome 10 at 31,379,256 bp
  • T to A, chromosome 10 at 36,989,184 bp
  • A to T, chromosome 10 at 52,400,437 bp
  • A to T, chromosome 10 at 62,621,377 bp
  • A to G, chromosome 10 at 127,022,929 bp
  • A to G, chromosome 11 at 54,265,680 bp
  • A to C, chromosome 11 at 73,111,342 bp
  • G to T, chromosome 11 at 97,444,328 bp
  • T to G, chromosome 12 at 114,565,037 bp
  • A to G, chromosome 12 at 116,367,710 bp
  • C to T, chromosome 14 at 50,829,693 bp
  • T to C, chromosome 14 at 50,963,177 bp
  • T to C, chromosome 15 at 3,986,294 bp
  • T to C, chromosome 15 at 35,887,261 bp
  • C to T, chromosome 15 at 89,334,454 bp
  • A to G, chromosome 15 at 93,510,777 bp
  • T to C, chromosome 16 at 30,067,250 bp
  • C to T, chromosome 17 at 30,274,942 bp
  • G to A, chromosome 18 at 38,261,264 bp
  • T to C, chromosome 19 at 21,598,201 bp
  • T to A, chromosome 19 at 23,718,095 bp
  • A to G, chromosome 19 at 33,501,606 bp
  • G to T, chromosome 19 at 42,766,180 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0134 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038419-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.