Strain Name:
C57BL/6J-MtgxR0167Btlr/Mmmh
Stock Number:
038443-MU
Citation ID:
RRID:MMRRC_038443-MU
Other Names:
R0167 (G1), C57BL/6J-MtgxR0167Btlr
Major Collection:

Strain Information

St8sia1
Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Synonyms: Siat8, GD3S, 9330109E03Rik, ST8Sia I, GD3 synthase, Siat8a, alpha-2,8-sialyltransferase
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20449
Homologene: 2282
Lrrn3
Name: leucine rich repeat protein 3, neuronal
Synonyms: NLRR-3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16981
VEGA: 12
Homologene: 36315
Trdmt1
Name: tRNA aspartic acid methyltransferase 1
Synonyms: Dnmt2, Rnmt2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13434
HGNC: HGNC:2977
Homologene: 3249
Lrp2
Name: low density lipoprotein receptor-related protein 2
Synonyms: Megalin, D230004K18Rik, Gp330, b2b1625.2Clo
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14725
HGNC: HGNC:6694
Homologene: 20952
Shroom3
Name: shroom family member 3
Synonyms: Shrm3, D5Ertd287e, Shrm
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 27428
Homologene: 9263
Prep
Name: prolyl endopeptidase
Synonyms: Pop, prolyl oligopeptidase, D10Wsu136e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19072
VEGA: 10
HGNC: HGNC:9358
Homologene: 2042
Setd2
Name: SET domain containing 2
Synonyms: KMT3A, 4921524K10Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235626
Homologene: 56493
Tpp2
Name: tripeptidyl peptidase II
Synonyms: TppII
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22019
Homologene: 2471
Med25
Name: mediator complex subunit 25
Synonyms: 2610034E13Rik, 2610529E18Rik, ESTM2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 75613
Homologene: 12614
Bltp3a
Name: bridge-like lipid transfer protein family member 3A
Synonyms: F830021D11Rik, Uhrf1bp1, 1110020K19Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224648
Homologene: 9816
Parg
Name: poly (ADP-ribose) glycohydrolase
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 26430
HGNC: HGNC:8605
Homologene: 50532
Dcaf4
Name: DDB1 and CUL4 associated factor 4
Synonyms: 1110018E21Rik, Wdr21
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 73828
VEGA: 12
Homologene: 9210
Hdac2
Name: histone deacetylase 2
Synonyms: D10Wsu179e, Yy1bp
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 15182
HGNC: HGNC:4853
Homologene: 68187
Golga1
Name: golgin A1
Synonyms: awag, golgin-97, 0710001G09Rik, Golgi97, 2210418B03Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 76899
HGNC: HGNC:4424
Homologene: 68223
Psip1
Name: PC4 and SFRS1 interacting protein 1
Synonyms: Psip2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 101739
HGNC: HGNC:9527
Homologene: 13242
Hey2
Name: hairy/enhancer-of-split related with YRPW motif 2
Synonyms: bHLHb32, Hesr2, Hrt2, Herp1, CHF1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 15214
HGNC: HGNC:4881
Homologene: 22705
Galnt14
Name: polypeptide N-acetylgalactosaminyltransferase 14
Synonyms: 0610033M06Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 71685
Homologene: 56997
Uggt1
Name: UDP-glucose glycoprotein glucosyltransferase 1
Synonyms: A930007H10Rik, 0910001L17Rik, Ugcgl1, C820010P03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 320011
Homologene: 10586
Clcn1
Name: chloride channel, voltage-sensitive 1
Synonyms: nmf355, Clc1, NMF355, Clc-1, SMCC1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12723
HGNC: HGNC:2019
Homologene: 63
Elane
Name: elastase, neutrophil expressed
Synonyms: Ela2, F430011M15Rik, NE
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 50701
VEGA: 10
HGNC: HGNC:3309
Homologene: 20455
Ttn
Name: titin
Synonyms: connectin, 1100001C23Rik, D330041I19Rik, D830007G01Rik, 2310074I15Rik, 2310036G12Rik, mdm, 2310057K23Rik, shru, L56
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Vmn1r28
Name: vomeronasal 1 receptor 28
Synonyms: V1rc25
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171198
Homologene: 138094
Ahrr
Name: aryl-hydrocarbon receptor repressor
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 11624
HGNC: HGNC:346
Homologene: 49215
Cdh5
Name: cadherin 5
Synonyms: 7B4/cadherin-5, VEC, VEcad, CD144, VECD, VE-Cad, VE-cadherin
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12562
HGNC: HGNC:1764
Homologene: 1359
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241516
Homologene: 110349
Cpne2
Name: copine II
Synonyms: 3322401K10Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234577
HGNC: HGNC:2315
Homologene: 27392
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12835
HGNC: HGNC:2213
Homologene: 37917
Zfp804a
Name: zinc finger protein 804A
Synonyms: C630007C17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241514
Homologene: 18461
Otog
Name: otogelin
Synonyms: Otgn
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18419
HGNC: HGNC:8516
Homologene: 8421
Eya2
Name: EYA transcriptional coactivator and phosphatase 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14049
HGNC: HGNC:3520
Homologene: 40711
Or5ac23
Name: olfactory receptor family 5 subfamily AC member 23
Synonyms: MOR182-11P, GA_x54KRFPKG5P-55543875-55542958, Olfr205
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 257881
Homologene: 79469
Rbbp8
Name: retinoblastoma binding protein 8, endonuclease
Synonyms: CtIP, 9930104E21Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225182
VEGA: 18
HGNC: HGNC:9891
Homologene: 28546
Bsn
Name: bassoon
Synonyms: presynaptic cytomatrix protein
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12217
HGNC: HGNC:1117
Homologene: 31161
Thbs2
Name: thrombospondin 2
Synonyms: TSP2, Thrombospondin-2, Thbs-2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21826
VEGA: 17
Homologene: 2438
Dlk2
Name: delta like non-canonical Notch ligand 2
Synonyms: Egfl9
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106565
Homologene: 11397
D630023F18Rik
Name: RIKEN cDNA D630023F18 gene
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98303
Homologene: 129674
Rhbdd1
Name: rhomboid domain containing 1
Synonyms: 4930418P06Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 76867
Homologene: 12659
Fam171a1
Name: family with sequence similarity 171, member A1
Synonyms: 9630050M13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269233
Homologene: 19521
Shc4
Name: SHC (Src homology 2 domain containing) family, member 4
Synonyms: 6230417E10Rik, 9930029B02Rik, LOC271849
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 271849
Homologene: 19567
Mup5
Name: major urinary protein 5
Synonyms: Mup V
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 17844
Homologene: 74304
Ccdc96
Name: coiled-coil domain containing 96
Synonyms: 4921513E08Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 66717
Homologene: 32639
Cckar
Name: cholecystokinin A receptor
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12425
HGNC: HGNC:1570
Homologene: 37337
Ift22
Name: intraflagellar transport 22
Synonyms: 3110017O03Rik, Rabl5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67286
Homologene: 11253
Prss1l
Name: serine protease 1 (trypsin 1) like
Synonyms: Gm5771
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 436523
Homologene: 88408
Or51aa5
Name: olfactory receptor family 51 subfamily AA member 5
Synonyms: Olfr611, MOR15-1, MOR15-4, GA_x6K02T2PBJ9-6236637-6235666
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258722
Homologene: 79675
Clpx
Name: caseinolytic mitochondrial matrix peptidase chaperone subunit
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270166
HGNC: HGNC:2088
Homologene: 4851
Snx14
Name: sorting nexin 14
Synonyms: YR-14, C330035N22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244962
Homologene: 17823
Actl11
Name: actin-like 11
Synonyms: 4921517D21Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67722
Homologene: 69412
Vstm2a
Name: V-set and transmembrane domain containing 2A
Synonyms: Vstm2, 9330184N17Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 211739
Homologene: 17123
H1f6
Name: H1.6 linker histone, cluster member
Synonyms: H1ft, Hist1h1t, H1t
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 107970
HGNC: HGNC:4720
Homologene: 3889
Dubr
Name: Dppa2 upstream binding RNA
Synonyms: 5330426P16Rik, Dum
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 68190
Or9q2
Name: olfactory receptor family 9 subfamily Q member 2
Synonyms: GA_x6K02T2RE5P-4127765-4126821, Olfr1497, MOR212-1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258736
Homologene: 17373
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 36,170,197 bp
  • T to C, chromosome 1 at 43,970,488 bp
  • A to G, chromosome 1 at 65,117,181 bp
  • T to C, chromosome 1 at 82,342,784 bp
  • C to T, chromosome 1 at 90,798,173 bp
  • C to T, chromosome 2 at 3,186,432 bp
  • A to T, chromosome 2 at 13,516,018 bp
  • T to C, chromosome 2 at 39,047,648 bp
  • T to C, chromosome 2 at 69,425,658 bp
  • T to A, chromosome 2 at 76,889,523 bp
  • T to G, chromosome 2 at 82,256,516 bp
  • T to A, chromosome 2 at 82,980,807 bp
  • T to G, chromosome 2 at 125,723,013 bp
  • T to G, chromosome 2 at 165,716,112 bp
  • T to A, chromosome 4 at 61,833,782 bp
  • T to C, chromosome 4 at 83,466,818 bp
  • T to C, chromosome 5 at 36,485,153 bp
  • A to T, chromosome 5 at 53,706,453 bp
  • T to C, chromosome 5 at 92,948,395 bp
  • T to C, chromosome 5 at 136,911,891 bp
  • T to A, chromosome 6 at 41,396,261 bp
  • T to C, chromosome 6 at 42,286,836 bp
  • G to A, chromosome 6 at 58,265,717 bp
  • A to G, chromosome 6 at 142,914,181 bp
  • A to G, chromosome 7 at 44,883,097 bp
  • G to A, chromosome 7 at 46,304,231 bp
  • A to T, chromosome 7 at 103,517,501 bp
  • T to C, chromosome 8 at 94,568,579 bp
  • A to C, chromosome 8 at 104,136,735 bp
  • G to A, chromosome 9 at 65,316,737 bp
  • A to T, chromosome 9 at 88,407,416 bp
  • T to C, chromosome 9 at 107,929,770 bp
  • T to C, chromosome 9 at 108,125,986 bp
  • T to A, chromosome 9 at 110,573,782 bp
  • A to G, chromosome 10 at 30,840,665 bp
  • T to C, chromosome 10 at 37,000,372 bp
  • A to G, chromosome 10 at 45,158,230 bp
  • T to A, chromosome 10 at 79,887,099 bp
  • T to A, chromosome 11 at 16,258,044 bp
  • T to A, chromosome 12 at 41,454,015 bp
  • G to A, chromosome 12 at 83,535,988 bp
  • T to C, chromosome 13 at 23,695,903 bp
  • G to A, chromosome 13 at 74,283,024 bp
  • T to C, chromosome 14 at 32,217,736 bp
  • G to T, chromosome 16 at 50,732,644 bp
  • A to T, chromosome 16 at 59,328,974 bp
  • A to T, chromosome 17 at 14,667,525 bp
  • C to T, chromosome 17 at 27,880,202 bp
  • C to A, chromosome 17 at 46,302,604 bp
  • T to C, chromosome 17 at 73,522,720 bp
  • T to A, chromosome 18 at 11,660,922 bp
  • T to C, chromosome 19 at 13,795,567 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0167 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038443-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.