Beutler Mutagenetix

Strain Name:
C57BL/6J-MtgxR0219Btlr/Mmmh
Stock Number:
038468-MU
Citation ID:
RRID:MMRRC_038468-MU
Other Names:
R0219 (G1), C57BL/6J-MtgxR0219Btlr
Major Collection:

Gene Information

Utrn
Name: utrophin
Synonyms: G-utrophin, DRP, Dmdl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 22288
VEGA: 10
Homologene: 21398
Dicer1
Name: dicer 1, ribonuclease type III
Synonyms: D12Ertd7e, 1110006F08Rik, Dicer1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 192119
VEGA: 12
Homologene: 13251
Dysf
Name: dysferlin
Synonyms: 2310004N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 26903
HGNC: HGNC:3097
Homologene: 20748
Dst
Name: dystonin
Synonyms: A830042E19Rik, 2310001O04Rik, Macf2, bullous pemphigoid antigen 1, BPAG1-n, BPAG1, athetoid, Bpag, ah, bullous pemphigoid antigen 1, Bpag1, nmf339, nmf203
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Utp20
Name: UTP20 small subunit processome component
Synonyms: DRIM, 3830408P06Rik, mDRIM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 70683
VEGA: 10
Homologene: 38373
Kdm4c
Name: lysine (K)-specific demethylase 4C
Synonyms: 2410141F18Rik, Jmjd2c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 76804
Homologene: 41004
Lrp5
Name: low density lipoprotein receptor-related protein 5
Synonyms: LRP7, LR3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 16973
HGNC: HGNC:6697
Homologene: 1746
Aff1
Name: AF4/FMR2 family, member 1
Synonyms: Mllt2h, Af4, 9630032B01Rik, Rob
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 17355
HGNC: HGNC:7135
Homologene: 4340
Hnrnpr
Name: heterogeneous nuclear ribonucleoprotein R
Synonyms: hnRNPR, 2610528B01Rik, 2610003J05Rik, Hnrpr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 74326
HGNC: HGNC:5047
Homologene: 4251
Tpr
Name: translocated promoter region, nuclear basket protein
Synonyms: 2610029M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 108989
Homologene: 37753
Ankle2
Name: ankyrin repeat and LEM domain containing 2
Synonyms: D5Ertd585e, 1110001J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71782
Homologene: 35424
Dclk2
Name: doublecortin-like kinase 2
Synonyms: Dcamkl2, Click-II, 6330415M09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 70762
Homologene: 69431
Zfp442
Name: zinc finger protein 442
Synonyms: OTTMUSG00000015730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 668923
HGNC: null
Homologene: 136215
Dgkd
Name: diacylglycerol kinase, delta
Synonyms: DGKdelta, dgkd-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227333
HGNC: HGNC:2851
Homologene: 100054
Ccdc80
Name: coiled-coil domain containing 80
Synonyms: DRO1, 2610001E17Rik, Ssg1, Urb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 67896
Homologene: 12206
Cdhr1
Name: cadherin-related family member 1
Synonyms: Pcdh21, Prcad
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 170677
VEGA: 14
Homologene: 13215
Bcl2
Name: B cell leukemia/lymphoma 2
Synonyms: D830018M01Rik, Bcl-2, C430015F12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12043
HGNC: HGNC:990
Homologene: 527
Fcer1g
Name: Fc receptor, IgE, high affinity I, gamma polypeptide
Synonyms: Ly-50, Fce1g, FcepsilonRI, FcR[g], FcR-gamma, FcRgamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 14127
HGNC: HGNC:3611
Homologene: 3029
Krt25
Name: keratin 25
Synonyms: 4631426H08Rik, mIRSa1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 70810
Homologene: 77127
Vps13d
Name: vacuolar protein sorting 13D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230895
Homologene: 15583
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: p600, A930005E13Rik, 1810009A16Rik, LOC381562, D930005K06Rik, Zubr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 69116
Homologene: 10804
Zfp738
Name: zinc finger protein 738
Synonyms: 3830402I07Rik, 6720487G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 408068
Homologene: 133713
Nptx2
Name: neuronal pentraxin 2
Synonyms: narp, np2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 53324
HGNC: HGNC:7953
Homologene: 1892
Kank4
Name: KN motif and ankyrin repeat domains 4
Synonyms: Ankrd38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242553
Homologene: 18244
Glb1l2
Name: galactosidase, beta 1-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244757
Homologene: 71790
Brca2
Name: breast cancer 2, early onset
Synonyms: Fancd1, RAB163
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12190
HGNC: HGNC:1101
Homologene: 41
Ccdc171
Name: coiled-coil domain containing 171
Synonyms: 4930418J05Rik, A330015D16Rik, 4930473A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 320226
Homologene: 27942
Isx
Name: intestine specific homeobox
Synonyms: 9130012O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 71597
Homologene: 28312
Sv2b
Name: synaptic vesicle glycoprotein 2 b
Synonyms: A830038F04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 64176
Homologene: 32236
Cilp
Name: cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
Synonyms: C130036G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 214425
HGNC: HGNC:1980
Homologene: 2679
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Tmprss7
Name: transmembrane serine protease 7
Synonyms: LOC385645, matriptase-3, B230219I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 208171
Homologene: 18178
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: D12Ertd777e, Nesp2g, nesprin-2, syne-2, dice, Cpfl8, 6820443O06Rik, diminished cone electroretinogram
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 319565
Homologene: 56700
Kcp
Name: kielin/chordin-like protein
Synonyms: KCP, LOC333088, Crim2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 333088
Homologene: 87817
Acacb
Name: acetyl-Coenzyme A carboxylase beta
Synonyms: Accb, Acc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100705
HGNC: HGNC:85
Homologene: 74382
Mylk3
Name: myosin light chain kinase 3
Synonyms: D830007F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 213435
Homologene: 35278
Ccdc116
Name: coiled-coil domain containing 116
Synonyms: 4930432J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 76872
Homologene: 51873
Pus7
Name: pseudouridylate synthase 7
Synonyms: C330017I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 78697
Homologene: 6998
Nav3
Name: neuron navigator 3
Synonyms: 9630020C08Rik, Pomfil1p, 4732483H20Rik, unc53H3, steerin 3, POMFIL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 260315
Homologene: 56688
Slc6a18
Name: solute carrier family 6 (neurotransmitter transporter), member 18
Synonyms: XT2, Xtrp2, D630001K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 22598
VEGA: 13
Homologene: 40785
Olfr520
Name: olfactory receptor 520
Synonyms: GA_x6K02T2PBJ9-2411789-2412739, MOR101-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259066
Homologene: 17484
Vmn2r116
Name: vomeronasal 2, receptor 116
Synonyms: EG619697, V2Rp5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 619697
HGNC: null
Homologene: 86604
Zfp629
Name: zinc finger protein 629
Synonyms: 9330199A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 320683
Homologene: 65318
Fbp2
Name: fructose bisphosphatase 2
Synonyms: FBPase muscle, Fbp-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 14120
VEGA: 13
HGNC: HGNC:3607
Homologene: 55784
Stxbp5
Name: syntaxin binding protein 5 (tomosyn)
Synonyms: LGL3, 0710001E20Rik, 4930565N16Rik, tomosyn 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 78808
Homologene: 16402
Farp1
Name: FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
Synonyms: Cdep
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 223254
HGNC: HGNC:3591
Homologene: 38098
Map3k10
Name: mitogen-activated protein kinase kinase kinase 10
Synonyms: MKN28 kinase, MKN28 derived nonreceptor_type, serine/threonine kinase, Mlk2, mixed lineage kinase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 269881
HGNC: HGNC:6849
Homologene: 1834
Guf1
Name: GUF1 homolog, GTPase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231279
Homologene: 6505
Vmn2r5
Name: vomeronasal 2, receptor 5
Synonyms: EG667060
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 667060
HGNC: null
Homologene: null
Abcb5
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 5
Synonyms: 9230106F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 77706
HGNC: HGNC:46
Homologene: 83488
Shkbp1
Name: Sh3kbp1 binding protein 1
Synonyms: SB1, B930062H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 192192
Homologene: 26700
Necab3
Name: N-terminal EF-hand calcium binding protein 3
Synonyms: Nip1, XB51, 2900010M17Rik, Apba2bp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 56846
Homologene: 10992
Zfp212
Name: Zinc finger protein 212
Synonyms: Znf212
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232784
Homologene: 8170
Ccna1
Name: cyclin A1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 12427
HGNC: HGNC:1577
Homologene: 31203
Togaram2
Name: TOG array regulator of axonemal microtubules 2
Synonyms: Fam179a, 4632412N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 320159
Homologene: 65315
Ddx59
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
Synonyms: 1210002B07Rik, 4833411G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 67997
Homologene: 12222
Olfr414
Name: olfactory receptor 414
Synonyms: MOR103-10, GA_x6K02T2P20D-20749615-20748662
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 258756
Homologene: 17383
Rad21l
Name: RAD21-like (S. pombe)
Synonyms: Gm14160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 668929
Homologene: 82650
Gm9912
Name: predicted gene 9912
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: null
Ensembl: null
VEGA: null
HGNC: null
Homologene: null
Iglon5
Name: IgLON family member 5
Synonyms: A230106M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 210094
Homologene: 46295
Mrgprx1
Name: MAS-related GPR, member X1
Synonyms: Mrgprc11, MrgC11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 404242
Homologene: 86184
Hbb-b1
Name: hemoglobin, beta adult major chain
Synonyms: beta major globin, MommeD7, beta1, beta maj
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: null
Ensembl: null
VEGA: null
HGNC: null
Homologene: null
Ncan
Name: neurocan
Synonyms: Tgfbit, Cspg3, Cspg3-rs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 13004
HGNC: HGNC:2465
Homologene: 3229
Rptoros
Name: regulatory associated protein of MTOR, complex 1, opposite strand
Synonyms: A430071A18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 319454
HGNC: null
Homologene: null
Tmem174
Name: transmembrane protein 174
Synonyms: 0610009B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 68344
VEGA: 13
Homologene: 17711
Pde6a
Name: phosphodiesterase 6A, cGMP-specific, rod, alpha
Synonyms: Pdea
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225600
HGNC: HGNC:8785
Homologene: 380
Sart1
Name: squamous cell carcinoma antigen recognized by T cells 1
Synonyms: U5-110K
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 20227
VEGA: 19
Homologene: 133770
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to G, chromosome 1 at 34,303,478 bp
  • T to C, chromosome 1 at 87,938,274 bp
  • G to A, chromosome 1 at 106,712,562 bp
  • C to A, chromosome 1 at 136,432,309 bp
  • T to C, chromosome 1 at 150,443,258 bp
  • A to G, chromosome 1 at 171,231,226 bp
  • G to A, chromosome 1 at 174,430,466 bp
  • T to C, chromosome 2 at 76,900,228 bp
  • A to T, chromosome 2 at 150,411,240 bp
  • A to G, chromosome 2 at 151,654,588 bp
  • G to T, chromosome 2 at 154,546,093 bp
  • T to C, chromosome 3 at 55,050,927 bp
  • A to G, chromosome 3 at 64,504,313 bp
  • T to C, chromosome 3 at 86,813,669 bp
  • T to C, chromosome 3 at 149,185,495 bp
  • T to C, chromosome 4 at 74,373,620 bp
  • A to G, chromosome 4 at 83,696,441 bp
  • T to C, chromosome 4 at 98,778,465 bp
  • T to A, chromosome 4 at 136,339,163 bp
  • T to A, chromosome 4 at 139,430,257 bp
  • C to T, chromosome 4 at 145,105,909 bp
  • T to C, chromosome 5 at 23,775,966 bp
  • G to A, chromosome 5 at 69,559,586 bp
  • GCTCTCTCTC to GCTCTCTCTCTC, chromosome 5 at 103,811,040 bp
  • C to T, chromosome 5 at 110,251,645 bp
  • T to A, chromosome 5 at 114,232,944 bp
  • T to C, chromosome 5 at 144,548,140 bp
  • A to G, chromosome 5 at 150,523,175 bp
  • T to A, chromosome 6 at 29,495,785 bp
  • G to A, chromosome 6 at 47,926,685 bp
  • G to A, chromosome 6 at 84,129,461 bp
  • T to C, chromosome 7 at 27,352,061 bp
  • T to C, chromosome 7 at 27,656,731 bp
  • A to T, chromosome 7 at 43,476,837 bp
  • C to A, chromosome 7 at 48,021,546 bp
  • A to G, chromosome 7 at 75,157,267 bp
  • A to T, chromosome 7 at 99,735,928 bp
  • T to C, chromosome 7 at 103,826,669 bp
  • T to C, chromosome 7 at 127,612,083 bp
  • A to G, chromosome 8 at 70,115,334 bp
  • C to A, chromosome 8 at 74,889,961 bp
  • T to A, chromosome 8 at 85,355,244 bp
  • A to G, chromosome 9 at 26,806,322 bp
  • C to A, chromosome 9 at 65,269,590 bp
  • T to C, chromosome 10 at 9,770,528 bp
  • T to C, chromosome 10 at 12,684,451 bp
  • T to C, chromosome 10 at 88,764,675 bp
  • C to T, chromosome 10 at 109,866,930 bp
  • G to A, chromosome 11 at 99,318,059 bp
  • A to T, chromosome 11 at 119,821,777 bp
  • A to T, chromosome 12 at 76,042,004 bp
  • A to G, chromosome 12 at 104,692,125 bp
  • A to T, chromosome 12 at 118,886,150 bp
  • A to T, chromosome 13 at 62,854,048 bp
  • A to G, chromosome 13 at 67,683,389 bp
  • A to T, chromosome 13 at 73,674,632 bp
  • A to C, chromosome 13 at 98,636,839 bp
  • A to C, chromosome 14 at 37,079,601 bp
  • C to A, chromosome 14 at 121,243,600 bp
  • T to A, chromosome 16 at 17,141,612 bp
  • A to G, chromosome 16 at 45,096,483 bp
  • A to G, chromosome 16 at 45,656,457 bp
  • T to A, chromosome 17 at 23,386,098 bp
  • T to C, chromosome 17 at 71,714,230 bp
  • A to G, chromosome 18 at 61,285,935 bp
  • A to T, chromosome 19 at 3,597,349 bp
  • C to A, chromosome 19 at 5,388,396 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0219 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038468-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.