Strain Name:
C57BL/6J-MtgxR0256Btlr/Mmmh
Stock Number:
038487-MU
Citation ID:
RRID:MMRRC_038487-MU
Other Names:
R0256 (G1), C57BL/6J-MtgxR0256Btlr
Major Collection:

Gene Information

Slc35a1
Name: solute carrier family 35 (CMP-sialic acid transporter), member 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 24060
Homologene: 38181
Abce1
Name: ATP-binding cassette, sub-family E (OABP), member 1
Synonyms: Rnaseli, RNS4l (Eye), Oabp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 24015
HGNC: HGNC:69
Homologene: 2205
Zfp423
Name: zinc finger protein 423
Synonyms: ataxia1, Roaz, Ebfaz, Zfp104
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 94187
Homologene: 9010
Pigv
Name: phosphatidylinositol glycan anchor biosynthesis, class V
Synonyms: D430024F16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230801
Homologene: 5354
Mok
Name: MOK protein kinase
Synonyms: MAPK/MAK/MRK/ overlapping kinase, MOK, Stk30, Rage
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 26448
HGNC: HGNC:9833
Homologene: 8062
Hic2
Name: hypermethylated in cancer 2
Synonyms: HRG22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 58180
Homologene: 9020
Tnks
Name: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
Synonyms: 4930554K12Rik, D130072O21Rik, mTNKS1, TANK1, tankyrase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 21951
Homologene: 18405
Chmp2b
Name: charged multivesicular body protein 2B
Synonyms: chromatin modifying protein 2B, 1190006E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 68942
VEGA: 16
Homologene: 8534
4932438A13Rik
Name: RIKEN cDNA 4932438A13 gene
Synonyms: FSA, Tweek
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229227
Homologene: 52105
Son
Name: Son DNA binding protein
Synonyms: 2900011L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 20658
Homologene: 10551
Kcnn2
Name: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
Synonyms: bc, small conductance calcium-activated potassium channel 2, SK2, fri
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 140492
HGNC: HGNC:6291
Homologene: 135651
Noct
Name: nocturnin
Synonyms: Ccr4, Ccrn4l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 12457
Homologene: 7661
Ror1
Name: receptor tyrosine kinase-like orphan receptor 1
Synonyms: Ntrkr1, 2810404D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 26563
Homologene: 3675
Foxk1
Name: forkhead box K1
Synonyms: Mnf, A630048H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 17425
Homologene: 82414
Zfp142
Name: zinc finger protein 142
Synonyms: 9330177B18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 77264
Homologene: 3723
Apip
Name: APAF1 interacting protein
Synonyms: Mmrp19, CGI-29, APIP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 56369
Homologene: 6277
Cdh6
Name: cadherin 6
Synonyms: K-cadherin, cad6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 12563
VEGA: 15
HGNC: HGNC:1765
Homologene: 21027
Cmtr1
Name: cap methyltransferase 1
Synonyms: Ftsjd2, 1300018I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 74157
Homologene: 9003
Ramp1
Name: receptor (calcitonin) activity modifying protein 1
Synonyms: 9130218E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 51801
HGNC: HGNC:9843
Homologene: 4275
Smco2
Name: single-pass membrane protein with coiled-coil domains 2
Synonyms: 1700023A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 69371
Homologene: 106211
Prkag3
Name: protein kinase, AMP-activated, gamma 3 non-catalytic subunit
Synonyms: AMPKg3L, AMPKg3, AMPKg3S
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241113
HGNC: HGNC:9387
Homologene: 23006
Zfp648
Name: zinc finger protein 648
Synonyms: Gm10178, LOC207678
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 100503355
Homologene: 18996
Armc3
Name: armadillo repeat containing 3
Synonyms: 4921513G22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 70882
Homologene: 31589
Fhl5
Name: four and a half LIM domains 5
Synonyms: 1700027G07Rik, ACT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 57756
Homologene: 23230
Krt73
Name: keratin 73
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223915
Homologene: 27875
Olfr1106
Name: olfactory receptor 1106
Synonyms: GA_x6K02T2Q125-48541463-48540525, MOR172-8_p, MOR172-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258747
Homologene: 27251
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC5, MUC9, 2300002I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Stil
Name: Scl/Tal1 interrupting locus
Synonyms: Sil
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 20460
Homologene: 2283
Selenbp2
Name: selenium binding protein 2
Synonyms: AP56, Lpsb2, acetaminophen-binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20342
Homologene: 2930
Olfr372
Name: olfactory receptor 372
Synonyms: GA_x6K02T2NUPS-191522-192466, MOR282-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 404315
Homologene: 17287
Atp8b5
Name: ATPase, class I, type 8B, member 5
Synonyms: 4930417M19Rik, FetA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 320571
Homologene: 99882
Gm15217
Name: predicted gene 15217
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 100041724
Ivl
Name: involucrin
Synonyms: 1110019C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 16447
HGNC: HGNC:6187
Homologene: 137207
Clca3a1
Name: chloride channel accessory 3A1
Synonyms: Clca1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 12722
Homologene: 77224
Muc3
Name: mucin 3, intestinal
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 666339
Homologene: 141159
Sval3
Name: seminal vesicle antigen-like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 387564
Homologene: 133811
Arg1
Name: arginase, liver
Synonyms: PGIF, AI, Arg-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 11846
VEGA: 10
HGNC: HGNC:663
Homologene: 29
9330159F19Rik
Name: RIKEN cDNA 9330159F19 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 212448
VEGA: 10
Homologene: 8804
Olfr813
Name: olfactory receptor 813
Synonyms: MOR108-3, GA_x6K02T2PULF-11535078-11536010
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258252
Homologene: 138308
Plscr3
Name: phospholipid scramblase 3
Synonyms: 2210403O21Rik, 2610037N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 70310
Homologene: 23219
Gm11596
Name: predicted gene 11596
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 670464
Homologene: 124486
Slc28a3
Name: solute carrier family 28 (sodium-coupled nucleoside transporter), member 3
Synonyms: Cnt3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 114304
Homologene: 32533
Acvrl1
Name: activin A receptor, type II-like 1
Synonyms: Alk1, Acvrlk1, Alk-1, activin receptor-like kinase-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 11482
HGNC: HGNC:175
Homologene: 20058
Krt7
Name: keratin 7
Synonyms: Krt2-7, K7, D15Wsu77e, Cytokeratin 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 110310
HGNC: HGNC:6445
Homologene: 4058
Ccdc154
Name: coiled-coil domain containing 154
Synonyms: ntl, LOC207209
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 207209
Homologene: 19361
Arrdc5
Name: arrestin domain containing 5
Synonyms: 1700013E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 76920
VEGA: 17
Homologene: 66277
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 74,578,158 bp
  • T to C, chromosome 1 at 74,741,171 bp
  • A to T, chromosome 1 at 91,196,919 bp
  • T to A, chromosome 1 at 154,205,668 bp
  • A to T, chromosome 2 at 19,269,216 bp
  • T to C, chromosome 2 at 87,049,056 bp
  • T to A, chromosome 2 at 103,088,571 bp
  • G to T, chromosome 3 at 36,917,773 bp
  • A to G, chromosome 3 at 51,250,474 bp
  • T to C, chromosome 3 at 92,571,843 bp
  • A to T, chromosome 3 at 94,699,701 bp
  • A to T, chromosome 3 at 144,730,879 bp
  • T to C, chromosome 4 at 25,213,624 bp
  • T to C, chromosome 4 at 34,668,962 bp
  • T to C, chromosome 4 at 43,302,576 bp
  • T to A, chromosome 4 at 100,409,745 bp
  • T to A, chromosome 4 at 115,023,685 bp
  • T to C, chromosome 4 at 133,665,751 bp
  • A to G, chromosome 5 at 137,146,691 bp
  • A to G, chromosome 5 at 142,453,681 bp
  • A to G, chromosome 6 at 41,972,905 bp
  • A to T, chromosome 6 at 146,861,746 bp
  • A to G, chromosome 7 at 141,841,395 bp
  • T to C, chromosome 7 at 141,843,258 bp
  • A to G, chromosome 8 at 34,861,547 bp
  • C to T, chromosome 8 at 72,058,400 bp
  • A to C, chromosome 8 at 79,685,943 bp
  • A to T, chromosome 8 at 87,773,634 bp
  • A to G, chromosome 10 at 24,916,458 bp
  • G to T, chromosome 10 at 29,222,256 bp
  • A to T, chromosome 10 at 129,857,037 bp
  • A to G, chromosome 11 at 69,850,054 bp
  • T to A, chromosome 11 at 99,792,716 bp
  • T to C, chromosome 12 at 110,808,105 bp
  • T to C, chromosome 13 at 58,573,500 bp
  • A to T, chromosome 14 at 46,380,396 bp
  • T to C, chromosome 15 at 13,053,782 bp
  • A to T, chromosome 15 at 101,137,121 bp
  • C to T, chromosome 15 at 101,423,309 bp
  • T to G, chromosome 15 at 101,801,936 bp
  • A to G, chromosome 16 at 17,257,513 bp
  • G to T, chromosome 16 at 65,540,192 bp
  • A to G, chromosome 16 at 91,656,584 bp
  • C to T, chromosome 17 at 25,170,632 bp
  • T to C, chromosome 17 at 29,697,124 bp
  • A to G, chromosome 17 at 56,294,382 bp
  • A to G, chromosome 18 at 45,592,405 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0256 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038487-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.