Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR0271Btlr/Mmmh
Stock Number:
038497-MU
Citation ID:
RRID:MMRRC_038497-MU
Other Names:
R0271 (G1), C57BL/6J-MtgxR0271Btlr
Major Collection:

Strain Information

Nes
Name: nestin
Synonyms: RC2, Marc2, ESTM46, Ifaprc2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18008
HGNC: HGNC:7756
Homologene: 136487
Pzp
Name: PZP, alpha-2-macroglobulin like
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 11287
Homologene: 104112
Slc35a1
Name: solute carrier family 35 (CMP-sialic acid transporter), member 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 24060
Homologene: 38181
Khdc4
Name: KH domain containing 4, pre-mRNA splicing factor
Synonyms: 2810403A07Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74200
Homologene: 41761
Dip2c
Name: disco interacting protein 2 homolog C
Synonyms: 2900024P20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 208440
Homologene: 40996
Wdr43
Name: WD repeat domain 43
Synonyms: 2610318G08Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 72515
VEGA: 17
Homologene: 38810
Ankrd17
Name: ankyrin repeat domain 17
Synonyms: 4933425K22Rik, Gtar, A130069E23Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 81702
Homologene: 82403
Tpx2
Name: TPX2, microtubule-associated
Synonyms: REPP86, DIL2, p100, 2610005B21Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 72119
HGNC: HGNC:1249
Homologene: 8107
Pcsk9
Name: proprotein convertase subtilisin/kexin type 9
Synonyms: Narc1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100102
Homologene: 17790
Gtf3c3
Name: general transcription factor IIIC, polypeptide 3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98488
HGNC: HGNC:4666
Homologene: 40805
Wars1
Name: tryptophanyl-tRNA synthetase1
Synonyms: Wars
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 22375
Homologene: 3084
Ccdc138
Name: coiled-coil domain containing 138
Synonyms: 6230424H07Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 76138
VEGA: 10
Homologene: 44912
Gm14496
Name: predicted gene 14496
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 672125
Homologene: 129606
Rad1
Name: RAD1 checkpoint DNA exonuclease
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 19355
HGNC: HGNC:9806
Homologene: 37695
Rpp30
Name: ribonuclease P/MRP 30 subunit
Synonyms: TSG15, Rnasep2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 54364
VEGA: 19
Homologene: 38180
Nipbl
Name: NIPBL cohesin loading factor
Synonyms: 4921518A06Rik, 4933421G18Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 71175
VEGA: 15
Homologene: 15850
Fgd2
Name: FYVE, RhoGEF and PH domain containing 2
Synonyms: tcs-2, Tcd-2, tcs2, Tcd2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 26382
HGNC: HGNC:3664
Homologene: 8438
Hspa1b
Name: heat shock protein 1B
Synonyms: hsp68, Hsp70.1, Hsp70-1, HSP70B1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 15511
HGNC: HGNC:5233
Homologene: 133785
Tab2
Name: TGF-beta activated kinase 1/MAP3K7 binding protein 2
Synonyms: 1110030N06Rik, Tak1 binding protein 2, A530078N03Rik, Map3k7ip2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 68652
Homologene: 9019
Nlrp1b
Name: NLR family, pyrin domain containing 1B
Synonyms: Nalp1b
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 637515
Homologene: 19080
Mipol1
Name: mirror-image polydactyly 1
Synonyms: 1700081O04Rik, 6030439O22Rik, D12Ertd19e
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 73490
Homologene: 16340
Wdr17
Name: WD repeat domain 17
Synonyms: 3010002I12Rik, B230207L18Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244484
Homologene: 12460
C7
Name: complement component 7
Synonyms: LOC383055
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 109828
VEGA: 15
HGNC: HGNC:1346
Homologene: 489
Impg1
Name: interphotoreceptor matrix proteoglycan 1
Synonyms: IMP150, SPACR, A930015H12Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 63859
HGNC: HGNC:6055
Homologene: 1201
Prss52
Name: serine protease 52
Synonyms: 1700049K14Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 73382
Homologene: 105740
Tcp10a
Name: t-complex protein 10a
Synonyms: T66A-a, D17Leh66aa, D17Leh66A, Tcp-10a, Gm10326
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21461
Homologene: 83254
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380698
Homologene: 70869
Dgkb
Name: diacylglycerol kinase, beta
Synonyms: DGK-beta, C630029D13Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217480
VEGA: 12
HGNC: HGNC:2850
Homologene: 37875
Slc38a7
Name: solute carrier family 38, member 7
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234595
Homologene: 41237
Or10q1b
Name: olfactory receptor family 10 subfamily Q member 1B
Synonyms: GA_x6K02T2RE5P-4037809-4038768, MOR266-8, Olfr1491
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258342
Mrpl37
Name: mitochondrial ribosomal protein L37
Synonyms: MRP-L2, Rpml2, 2300004O14Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 56280
Homologene: 9536
Vmn2r105
Name: vomeronasal 2, receptor 105
Synonyms: EG627743
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627743
Homologene: 129680
Zfp235
Name: zinc finger protein 235
Synonyms: 0610030O19Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56525
Homologene: 122146
Fanca
Name: Fanconi anemia, complementation group A
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14087
HGNC: HGNC:3582
Homologene: 108
Eml6
Name: echinoderm microtubule associated protein like 6
Synonyms: 2900083P10Rik, C230094A16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237711
Homologene: 104282
Sytl2
Name: synaptotagmin-like 2
Synonyms: Slp2-a, Slp2, Slp2-d, Slp2-c, Slp2-b
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 83671
Homologene: 131343
Lpcat4
Name: lysophosphatidylcholine acyltransferase 4
Synonyms: Aytl3, Agpat7, LPEAT2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99010
Homologene: 27544
Gm1110
Name: predicted gene 1110
Synonyms: LOC382064
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 382064
VEGA: 9
Homologene: 78608
Plxnc1
Name: plexin C1
Synonyms: vespr, 2510048K12Rik, CD232
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 54712
HGNC: HGNC:9106
Homologene: 4211
Tmprss13
Name: transmembrane protease, serine 13
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214531
Homologene: 12936
Or5m12
Name: olfactory receptor family 5 subfamily M member 12
Synonyms: GA_x6K02T2Q125-47384320-47383337, MOR197-1, Olfr1024
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 257900
Homologene: 128271
Phyhd1
Name: phytanoyl-CoA dioxygenase domain containing 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227696
Homologene: 14939
Or4a2
Name: olfactory receptor family 4 subfamily A member 2
Synonyms: GA_x6K02T2Q125-50861284-50860367, MOR231-3, Olfr1239
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258972
Homologene: 74244
Serpini2
Name: serine (or cysteine) peptidase inhibitor, clade I, member 2
Synonyms: 1810006A24Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67931
HGNC: HGNC:8945
Homologene: 21248
Gm12500
Name: predicted gene 12500
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 791415
Zkscan16
Name: zinc finger with KRAB and SCAN domains 16
Synonyms: Zfp483
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100041581
Homologene: 26419
Arhgef19
Name: Rho guanine nucleotide exchange factor 19
Synonyms: 6430573B13Rik, WGEF
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 213649
Homologene: 17710
Tnfrsf14
Name: tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
Synonyms: HveA, Atar, Hvem
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230979
Homologene: 2833
Myo18b
Name: myosin XVIIIb
Synonyms: 4932408L24Rik, 4933411E19Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 74376
Homologene: 53435
Or51q1
Name: olfactory receptor family 51 subfamily Q member 1
Synonyms: GA_x6K02T2PBJ9-6713641-6714588, MOR5-2, Olfr635
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259122
Homologene: 133592
4930544D05Rik
Name: RIKEN cDNA 4930544D05 gene
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 668433
Homologene: 109413
Rsad1
Name: radical S-adenosyl methionine domain containing 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237926
Homologene: 41252
Gm7008
Name: predicted gene 7008
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 629820
Pck2
Name: phosphoenolpyruvate carboxykinase 2 (mitochondrial)
Synonyms: 9130022B02Rik, 1810010O14Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 74551
VEGA: 14
HGNC: HGNC:8725
Homologene: 3356
Prss55
Name: serine protease 55
Synonyms: 4933401F05Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 71037
Homologene: 51233
Cpb2
Name: carboxypeptidase B2
Synonyms: thrombin-activatable fibrinolysis inhibitor, CPU, carboxypeptidase U, TAFI, 1110032P04Rik, carboxypeptidase R, CPR, 4930405E17Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 56373
VEGA: 14
HGNC: HGNC:2300
Homologene: 55610
Gm9922
Name: predicted gene 9922
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 102633345
VEGA: 14
Foxred2
Name: FAD-dependent oxidoreductase domain containing 2
Synonyms: LOC239554, A430097D04Rik, D15Bwg0759e
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239554
Homologene: 11800
Arhgap31
Name: Rho GTPase activating protein 31
Synonyms: CdGAP
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12549
Homologene: 10644
Ripply3
Name: ripply transcriptional repressor 3
Synonyms: Dscr6
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 170765
HGNC: HGNC:3047
Homologene: 10350
Washc1
Name: WASH complex subunit 1
Synonyms: 1110049F14Rik, ORF19, Wash, Wash1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 68767
VEGA: 17
Homologene: 45706
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 54,428,812 bp
  • A to T, chromosome 2 at 30,269,822 bp
  • A to C, chromosome 2 at 77,920,858 bp
  • A to T, chromosome 2 at 85,904,289 bp
  • T to A, chromosome 2 at 89,418,158 bp
  • T to A, chromosome 2 at 112,243,245 bp
  • A to G, chromosome 2 at 152,867,367 bp
  • A to T, chromosome 2 at 181,995,954 bp
  • A to G, chromosome 3 at 75,246,578 bp
  • G to A, chromosome 3 at 87,978,642 bp
  • T to C, chromosome 3 at 88,686,329 bp
  • C to T, chromosome 3 at 108,086,716 bp
  • T to A, chromosome 4 at 34,664,125 bp
  • G to A, chromosome 4 at 58,952,391 bp
  • A to G, chromosome 4 at 106,449,049 bp
  • C to A, chromosome 4 at 107,066,461 bp
  • G to T, chromosome 4 at 141,250,607 bp
  • A to G, chromosome 4 at 154,926,597 bp
  • T to C, chromosome 5 at 90,254,799 bp
  • T to C, chromosome 5 at 112,809,685 bp
  • A to T, chromosome 6 at 128,519,514 bp
  • A to T, chromosome 7 at 24,137,131 bp
  • T to C, chromosome 7 at 90,403,020 bp
  • T to A, chromosome 7 at 103,979,630 bp
  • C to T, chromosome 8 at 54,693,096 bp
  • A to G, chromosome 8 at 95,845,878 bp
  • A to G, chromosome 8 at 99,111,715 bp
  • T to C, chromosome 8 at 123,272,441 bp
  • A to G, chromosome 9 at 26,920,666 bp
  • A to G, chromosome 9 at 45,333,688 bp
  • T to C, chromosome 9 at 80,386,879 bp
  • G to A, chromosome 10 at 7,919,158 bp
  • G to A, chromosome 10 at 58,575,823 bp
  • C to T, chromosome 10 at 94,837,918 bp
  • A to G, chromosome 11 at 29,848,949 bp
  • T to G, chromosome 11 at 59,056,742 bp
  • A to G, chromosome 11 at 70,616,648 bp
  • T to C, chromosome 11 at 71,161,765 bp
  • T to C, chromosome 11 at 94,548,464 bp
  • T to A, chromosome 12 at 38,228,026 bp
  • T to A, chromosome 12 at 40,223,560 bp
  • T to C, chromosome 12 at 57,460,954 bp
  • C to T, chromosome 12 at 108,875,193 bp
  • A to G, chromosome 13 at 9,615,775 bp
  • T to C, chromosome 14 at 55,544,584 bp
  • C to T, chromosome 14 at 64,075,607 bp
  • T to C, chromosome 14 at 64,113,678 bp
  • C to T, chromosome 14 at 66,356,283 bp
  • T to A, chromosome 14 at 75,257,709 bp
  • T to A, chromosome 14 at 101,729,553 bp
  • T to C, chromosome 15 at 5,015,380 bp
  • A to T, chromosome 15 at 8,361,737 bp
  • T to C, chromosome 15 at 10,490,457 bp
  • A to C, chromosome 15 at 77,943,390 bp
  • T to G, chromosome 16 at 38,602,510 bp
  • A to T, chromosome 16 at 94,335,757 bp
  • A to G, chromosome 17 at 7,331,156 bp
  • T to A, chromosome 17 at 20,234,703 bp
  • C to G, chromosome 17 at 29,367,008 bp
  • A to G, chromosome 17 at 34,958,832 bp
  • T to A, chromosome 17 at 66,116,719 bp
  • A to G, chromosome 17 at 71,626,825 bp
  • A to T, chromosome 19 at 13,705,135 bp
  • T to A, chromosome 19 at 36,104,403 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0271 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038497-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.