Strain Name:
C57BL/6J-MtgxR0312Btlr/Mmmh
Stock Number:
038522-MU
Citation ID:
RRID:MMRRC_038522-MU
Other Names:
R0312 (G1), C57BL/6J-MtgxR0312Btlr
Major Collection:

Gene Information

Slc12a1
Name: solute carrier family 12, member 1
Synonyms: Nkcc2, mBSC1, D630042G03Rik, urehr3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20495
Homologene: 286
Slc1a3
Name: solute carrier family 1 (glial high affinity glutamate transporter), member 3
Synonyms: MGluT1, Eaat1, B430115D02Rik, GLAST, Gmt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20512
Homologene: 20882
Dlg1
Name: discs large MAGUK scaffold protein 1
Synonyms: B130052P05Rik, SAP97, Dlgh1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13383
HGNC: HGNC:2900
Homologene: 20869
Fryl
Name: FRY like transcription coactivator
Synonyms: 2310004H21Rik, 2510002A14Rik, 9030227G01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72313
Homologene: 103956
Dock5
Name: dedicator of cytokinesis 5
Synonyms: lr2, 1110060D06Rik, rlc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 68813
VEGA: 14
Homologene: 57016
Arhgap12
Name: Rho GTPase activating protein 12
Synonyms: 2810011M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 75415
Homologene: 23089
Plk4
Name: polo like kinase 4
Synonyms: Sak, Stk18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20873
Homologene: 7962
Xrcc6
Name: X-ray repair complementing defective repair in Chinese hamster cells 6
Synonyms: Ku p70, Ku70, G22p1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 14375
HGNC: HGNC:4055
Homologene: 37483
Lima1
Name: LIM domain and actin binding 1
Synonyms: 1110021C24Rik, 3526402A12Rik, epithelial protein lost in neoplasm, EPLIN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 65970
Homologene: 9484
G3bp1
Name: GTPase activating protein (SH3 domain) binding protein 1
Synonyms: GAP SH3 binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 27041
Homologene: 38096
Dhx40
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 40
Synonyms: ARG147, DDX40, 2410016C14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67487
Homologene: 57000
Topbp1
Name: topoisomerase (DNA) II binding protein 1
Synonyms: D430026L04Rik, 2810429C13Rik, 1110031N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235559
Homologene: 38262
Mnat1
Name: menage a trois 1
Synonyms: MAT1, E130115E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 17420
HGNC: HGNC:7181
Homologene: 1821
Adcy1
Name: adenylate cyclase 1
Synonyms: AC1, I-AC, D11Bwg1392e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 432530
HGNC: HGNC:232
Homologene: 41419
Apob
Name: apolipoprotein B
Synonyms: apob-100, apob-48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Cspp1
Name: centrosome and spindle pole associated protein 1
Synonyms: 4930413O22Rik, 2310020J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 211660
Homologene: 23487
Sema6a
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Synonyms: VIa, sema, Sema6A-1, Semaq, A730020P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 20358
Homologene: 32426
Gda
Name: guanine deaminase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 14544
HGNC: HGNC:4212
Homologene: 3171
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Bcl9
Name: B cell CLL/lymphoma 9
Synonyms: 8030475K17Rik, A330041G23Rik, 2610202E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 77578
HGNC: HGNC:1008
Homologene: 3191
Naa35
Name: N(alpha)-acetyltransferase 35, NatC auxiliary subunit
Synonyms: A330027C19Rik, A330021G12Rik, C030004C14Rik, Mak10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 78689
Homologene: 5781
Glt1d1
Name: glycosyltransferase 1 domain containing 1
Synonyms: 5730455A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 319804
Homologene: 16965
Lrch1
Name: leucine-rich repeats and calponin homology (CH) domain containing 1
Synonyms: 4832412D13Rik, Chdc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 380916
VEGA: 14
Homologene: 32244
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 94109
Homologene: 69536
Prdm14
Name: PR domain containing 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 383491
Homologene: 11556
Dnah10
Name: dynein, axonemal, heavy chain 10
Synonyms: Dnahc10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56087
HGNC: HGNC:2941
Homologene: 25816
Hsh2d
Name: hematopoietic SH2 domain containing
Synonyms: ALX, Hsh2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 209488
Homologene: 13142
Rab19
Name: RAB19, member RAS oncogene family
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19331
Homologene: 22623
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Pik3r4
Name: phosphoinositide-3-kinase regulatory subunit 4
Synonyms: Vps15, p150
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 75669
HGNC: HGNC:8982
Homologene: 24678
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Myo7b
Name: myosin VIIB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17922
HGNC: HGNC:7607
Homologene: 81947
Fbxw7
Name: F-box and WD-40 domain protein 7
Synonyms: SEL-10, AGO, Fbxo30, Fbxw6, 1110001A17Rik, Cdc4, Fbw7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 50754
Homologene: 117451
Ccdc54
Name: coiled-coil domain containing 54
Synonyms: 1700007N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 69339
VEGA: 16
Homologene: 49871
Vmn2r25
Name: vomeronasal 2, receptor 25
Synonyms: EG545874
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 545874
Homologene: 135915
Skint6
Name: selection and upkeep of intraepithelial T cells 6
Synonyms: OTTMUSG00000008519
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230622
Homologene: 135888
Kansl1l
Name: KAT8 regulatory NSL complex subunit 1-like
Synonyms: C430010P07Rik, 1110028C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68691
Homologene: 27376
Ugt2b37
Name: UDP glucuronosyltransferase 2 family, polypeptide B37
Synonyms: 0610033E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 112417
Homologene: 137225
Cfap65
Name: cilia and flagella associated protein 65
Synonyms: B230363K08Rik, Ccdc108
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241116
Homologene: 28093
Abcb5
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 5
Synonyms: 9230106F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 77706
HGNC: HGNC:46
Homologene: 83488
Sspo
Name: SCO-spondin
Synonyms: C79529, Scospondin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243369
Homologene: 45453
Bnc1
Name: basonuclin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12173
HGNC: HGNC:1081
Homologene: 31048
AC132131.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
4932415D10Rik
Name: RIKEN cDNA 4932415D10 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 102635990
VEGA: 10
Homologene: 82476
Dgkz
Name: diacylglycerol kinase zeta
Synonyms: mDGK[z], E130307B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 104418
HGNC: HGNC:2857
Homologene: 37831
Rtl1
Name: retrotransposon Gaglike 1
Synonyms: Mart1, Mor1, Mar
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 353326
VEGA: 12
Homologene: 120261
Or51q1c
Name: olfactory receptor family 51 subfamily Q member 1C
Synonyms: GA_x6K02T2PBJ9-6737723-6738670, MOR5-1, Olfr638
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259124
Homologene: 133592
Mpeg1
Name: macrophage expressed gene 1
Synonyms: Mpg-1, MPS1, Perforin-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 17476
VEGA: 19
Homologene: 11216
Phldb2
Name: pleckstrin homology like domain, family B, member 2
Synonyms: LL5beta, LL5b, C820004H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 208177
Homologene: 17100
Fggy
Name: FGGY carbohydrate kinase domain containing
Synonyms: 2310009E04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 75578
Homologene: 49535
Gm7647
Name: predicted gene 7647
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 108169099
Ism1
Name: isthmin 1, angiogenesis inhibitor
Synonyms: 5430433G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 319909
Homologene: 19061
Lrrc8e
Name: leucine rich repeat containing 8 family, member E
Synonyms: C87354, 1810049O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 72267
Homologene: 11817
Fpgs
Name: folylpolyglutamyl synthetase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14287
HGNC: HGNC:3824
Homologene: 6997
Or1j4
Name: olfactory receptor family 1 subfamily J member 4
Synonyms: GA_x6K02T2NLDC-33544602-33545540, MOR136-13, Olfr350
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258620
HGNC: HGNC:8211
Homologene: 64897
Lrp8os2
Name: low density lipoprotein receptor-related protein 8, apolipoprotein e receptor, opposite strand 2
Synonyms: B230314M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 619295
Evc
Name: EvC ciliary complex subunit 1
Synonyms: Ellis van Creveld gene syndrome
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 59056
HGNC: HGNC:3497
Homologene: 10949
Spata18
Name: spermatogenesis associated 18
Synonyms: 1700067I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 73472
Homologene: 17057
Pip
Name: prolactin induced protein
Synonyms: GCDFP-15, gross cystic disease fluid protein 15, mSMGP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 18716
HGNC: HGNC:8993
Homologene: 1990
Obox5
Name: oocyte specific homeobox 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 252829
Homologene: 44937
Hlf
Name: hepatic leukemia factor
Synonyms: E230015K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217082
HGNC: HGNC:4977
Homologene: 31074
Phyhip
Name: phytanoyl-CoA hydroxylase interacting protein
Synonyms: PAHX-AP#1, PAHX-AP1, C630010D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105653
Homologene: 8847
Or5h26
Name: olfactory receptor family 5 subfamily H member 26
Synonyms: GA_x54KRFPKG5P-55389051-55388122, MOR183-1, Olfr196
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 258775
Homologene: 74113
Gpr31c
Name: G protein-coupled receptor 31, D17Leh66c region
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 667359
VEGA: 17
Myrf
Name: myelin regulatory factor
Synonyms: LOC225908, LOC386531, Gm98
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225908
HGNC: HGNC:1181
Homologene: 32167
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 10,058,829 bp
  • G to A, chromosome 1 at 13,118,807 bp
  • T to C, chromosome 1 at 66,778,106 bp
  • G to A, chromosome 1 at 74,904,067 bp
  • A to G, chromosome 2 at 32,684,801 bp
  • A to T, chromosome 2 at 36,850,360 bp
  • A to G, chromosome 2 at 41,282,171 bp
  • A to T, chromosome 2 at 91,938,339 bp
  • A to G, chromosome 2 at 125,226,028 bp
  • G to T, chromosome 2 at 139,678,672 bp
  • C to T, chromosome 3 at 40,813,547 bp
  • T to C, chromosome 3 at 84,967,569 bp
  • C to T, chromosome 3 at 97,209,411 bp
  • A to C, chromosome 4 at 95,844,185 bp
  • T to C, chromosome 4 at 107,806,855 bp
  • A to T, chromosome 4 at 112,809,100 bp
  • C to T, chromosome 5 at 37,328,541 bp
  • T to A, chromosome 5 at 73,072,888 bp
  • G to A, chromosome 5 at 73,666,881 bp
  • C to T, chromosome 5 at 87,250,665 bp
  • T to C, chromosome 5 at 94,962,980 bp
  • G to A, chromosome 5 at 124,796,369 bp
  • A to G, chromosome 5 at 127,691,070 bp
  • G to A, chromosome 6 at 39,384,089 bp
  • G to A, chromosome 6 at 41,849,864 bp
  • C to T, chromosome 6 at 48,455,401 bp
  • A to T, chromosome 6 at 123,828,580 bp
  • T to A, chromosome 7 at 15,757,560 bp
  • C to T, chromosome 7 at 81,977,324 bp
  • T to C, chromosome 7 at 104,004,025 bp
  • T to A, chromosome 7 at 120,045,659 bp
  • A to G, chromosome 8 at 4,235,733 bp
  • A to T, chromosome 8 at 15,984,760 bp
  • G to A, chromosome 8 at 72,200,460 bp
  • A to G, chromosome 9 at 103,312,971 bp
  • A to G, chromosome 9 at 105,686,210 bp
  • A to T, chromosome 10 at 82,284,369 bp
  • A to G, chromosome 10 at 90,512,914 bp
  • G to T, chromosome 11 at 7,149,538 bp
  • T to C, chromosome 11 at 55,498,626 bp
  • G to A, chromosome 11 at 86,771,949 bp
  • G to A, chromosome 11 at 90,387,875 bp
  • T to A, chromosome 12 at 8,009,034 bp
  • A to G, chromosome 12 at 73,181,784 bp
  • G to T, chromosome 12 at 109,590,227 bp
  • G to T, chromosome 12 at 118,872,837 bp
  • A to G, chromosome 13 at 59,609,581 bp
  • G to C, chromosome 14 at 67,795,991 bp
  • G to T, chromosome 14 at 70,466,970 bp
  • G to T, chromosome 14 at 74,947,594 bp
  • C to T, chromosome 15 at 8,636,237 bp
  • C to A, chromosome 15 at 82,027,222 bp
  • A to G, chromosome 15 at 99,781,087 bp
  • A to G, chromosome 16 at 31,790,267 bp
  • G to T, chromosome 16 at 45,789,047 bp
  • T to C, chromosome 16 at 50,590,802 bp
  • A to T, chromosome 16 at 59,167,839 bp
  • C to T, chromosome 17 at 13,051,611 bp
  • T to C, chromosome 17 at 67,775,851 bp
  • A to G, chromosome 18 at 6,061,982 bp
  • T to C, chromosome 18 at 32,014,337 bp
  • G to A, chromosome 18 at 47,290,045 bp
  • G to C, chromosome 19 at 10,218,162 bp
  • C to A, chromosome 19 at 12,462,403 bp
  • T to A, chromosome 19 at 21,417,005 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0312 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038522-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.