Strain Name:
C57BL/6J-MtgxR0316Btlr/Mmmh
Stock Number:
038526-MU
Citation ID:
RRID:MMRRC_038526-MU
Other Names:
R0316 (G1), C57BL/6J-MtgxR0316Btlr
Major Collection:

Gene Information

Pkia
Name: protein kinase inhibitor, alpha
Synonyms: PKIalpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18767
HGNC: HGNC:9017
Homologene: 7473
Scn3a
Name: sodium channel, voltage-gated, type III, alpha
Synonyms: LOC381367, Nav1.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20269
Homologene: 56005
Ess2
Name: ess-2 splicing factor
Synonyms: ES2, Dgsi, D16H22S1269E, Es2el, Dgcr14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 27886
VEGA: 16
Homologene: 11184
Pxn
Name: paxillin
Synonyms: Pax
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19303
HGNC: HGNC:9718
Homologene: 37697
Nsd1
Name: nuclear receptor-binding SET-domain protein 1
Synonyms: KMT3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18193
VEGA: 13
Homologene: 32543
Rtel1
Name: regulator of telomere elongation helicase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 269400
Homologene: 13168
Nfkb1
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
Synonyms: NF kappaB1, p50 subunit of NF kappaB, p50/p105, p50, nuclear factor kappaB p50, NF-kappaB, NF-kappaB p50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18033
HGNC: HGNC:7794
Homologene: 2971
Asf1b
Name: anti-silencing function 1B histone chaperone
Synonyms: 1700003K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 66929
Homologene: 56797
Ago2
Name: argonaute RISC catalytic subunit 2
Synonyms: argonaute 2, 1110029L17Rik, 2310051F07Rik, Eif2c2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239528
HGNC: HGNC:3263
Homologene: 81825
Psma3
Name: proteasome subunit alpha 3
Synonyms: Lmpc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 19167
HGNC: HGNC:9532
Homologene: 2082
Pdcd11
Name: programmed cell death 11
Synonyms: ALG-4, 1110021I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18572
VEGA: 19
Homologene: 74968
Rnpc3
Name: RNA-binding region (RNP1, RRM) containing 3
Synonyms: C030014B17Rik, 2810441O16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67225
Homologene: 9746
Snapc1
Name: small nuclear RNA activating complex, polypeptide 1
Synonyms: 2700033G17Rik, 9630050P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 75627
VEGA: 12
Homologene: 2317
Marf1
Name: meiosis regulator and mRNA stability 1
Synonyms: 4921513D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 223989
VEGA: 16
Homologene: 40967
Tonsl
Name: tonsoku-like, DNA repair protein
Synonyms: 2810439M11Rik, Nfkbil2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 72749
HGNC: HGNC:7801
Homologene: 22754
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Thbs1
Name: thrombospondin 1
Synonyms: TSP1, TSP-1, Thbs-1, tbsp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 21825
Homologene: 31142
Prelid1
Name: PRELI domain containing 1
Synonyms: 2610524G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 66494
VEGA: 13
Homologene: 40859
Slit2
Name: slit guidance ligand 2
Synonyms: Slil3, Drad-1, E130320P19Rik, E030015M03Rik, b2b1200.1Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20563
Homologene: 3516
Zzz3
Name: zinc finger, ZZ domain containing 3
Synonyms: 3110065C23Rik, 6430567E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 108946
Homologene: 9182
Zdhhc18
Name: zinc finger, DHHC domain containing 18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 503610
Homologene: 110918
Pacs1
Name: phosphofurin acidic cluster sorting protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107975
VEGA: 19
Homologene: 9970
Ttc23
Name: tetratricopeptide repeat domain 23
Synonyms: 1600012K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67009
Homologene: 11289
Clca4a
Name: chloride channel accessory 4A
Synonyms: 9130020L07Rik, Clca6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99663
HGNC: HGNC:2018
Homologene: 40808
Pkd2
Name: polycystin 2, transient receptor potential cation channel
Synonyms: polycystin-2, C030034P18Rik, TRPP2, PC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18764
HGNC: HGNC:9009
Homologene: 20104
Trap1
Name: TNF receptor-associated protein 1
Synonyms: HSP75, 2410002K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 68015
Homologene: 9457
Tpcn1
Name: two pore channel 1
Synonyms: 5730403B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 252972
Homologene: 9905
Plxna2
Name: plexin A2
Synonyms: OCT, Plxn2, 2810428A13Rik, PlexA2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18845
HGNC: HGNC:9100
Homologene: 56427
Dnah1
Name: dynein, axonemal, heavy chain 1
Synonyms: MDHC7, E030034C22Rik, B230373P09Rik, Dnahc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 110084
VEGA: 14
HGNC: HGNC:2940
Homologene: 67131
Gm5901
Name: predicted gene 5901
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100503879
Homologene: 18311
Slc9c1
Name: solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
Synonyms: LOC208169, spermNHE, Slc9a10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 208169
Homologene: 19505
Svep1
Name: sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Synonyms: 4833413O10Rik, D430029O09Rik, 1110021D17Rik, Polydom
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 64817
Homologene: 23386
Col5a3
Name: collagen, type V, alpha 3
Synonyms: Pro-alpha3(V)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 53867
Homologene: 9253
Lama3
Name: laminin, alpha 3
Synonyms: nicein, 150kDa, [a]3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 16774
HGNC: HGNC:6483
Homologene: 18279
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Dcdc5
Name: doublecortin domain containing 5
Synonyms: 4732421G10Rik, EG436559
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329482
Homologene: 79722
Ptpro
Name: protein tyrosine phosphatase, receptor type, O
Synonyms: D28, PTPROt, PTP-phi, PTP-BK, PTP-U2, GLEPP1, PTP-oc, Ptpn15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19277
HGNC: HGNC:9678
Homologene: 21564
Ptchd3
Name: patched domain containing 3
Synonyms: 4933440L20Rik, 4930451E13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74675
Homologene: 111041
Capn7
Name: calpain 7
Synonyms: PalBH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 12339
HGNC: HGNC:1484
Homologene: 7651
Ado
Name: 2-aminoethanethiol (cysteamine) dioxygenase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 211488
VEGA: 10
Homologene: 13121
Fbn2
Name: fibrillin 2
Synonyms: sy, Sne, Fib-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 14119
VEGA: 18
HGNC: HGNC:3604
Homologene: 1515
Impg1
Name: interphotoreceptor matrix proteoglycan 1
Synonyms: IMP150, SPACR, A930015H12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 63859
HGNC: HGNC:6055
Homologene: 1201
Tnn
Name: tenascin N
Synonyms: Tnw, tenascin-W
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329278
Homologene: 18634
Dclk1
Name: doublecortin-like kinase 1
Synonyms: CPG16, DCLK, 1700113D08Rik, 2810480F11Rik, Dcl, Click-I, Dcamkl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 13175
HGNC: HGNC:2700
Homologene: 130530
Fgl2
Name: fibrinogen-like protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14190
HGNC: HGNC:3696
Homologene: 4864
Ptprt
Name: protein tyrosine phosphatase, receptor type, T
Synonyms: RPTPrho
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19281
HGNC: HGNC:9682
Homologene: 56924
Lipg
Name: lipase, endothelial
Synonyms: mEDL, 3110013K01Rik, endothelial lipase, EL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 16891
VEGA: 18
HGNC: HGNC:6623
Homologene: 21218
Serpina3n
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3N
Synonyms: Spi2-2, Spi2.2, Spi2/eb.4, antitrypsin, alpha-1 antiproteinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20716
HGNC: HGNC:16
Homologene: 111129
Greb1l
Name: growth regulation by estrogen in breast cancer-like
Synonyms: mKIAA4095, AK220484
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 381157
Homologene: 73393
Asic1
Name: acid-sensing (proton-gated) ion channel 1
Synonyms: BNaC2, ASIC, ASIC1a, ASICalpha, ASIC1 beta, B530003N02Rik, Accn2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 11419
VEGA: 15
HGNC: HGNC:100
Homologene: 121755
Olfr372
Name: olfactory receptor 372
Synonyms: GA_x6K02T2NUPS-191522-192466, MOR282-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 404315
Homologene: 17287
Gm5465
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Dcbld2
Name: discoidin, CUB and LCCL domain containing 2
Synonyms: 1700055P21Rik, Esdn, CLCP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 73379
Homologene: 12499
Col17a1
Name: collagen, type XVII, alpha 1
Synonyms: BPAg2, BP180, Bpag, Bpag2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 12821
HGNC: HGNC:2194
Homologene: 7276
Itih2
Name: inter-alpha trypsin inhibitor, heavy chain 2
Synonyms: Intin2, Itih-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16425
HGNC: HGNC:6167
Homologene: 1668
Spata13
Name: spermatogenesis associated 13
Synonyms: ESTM11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219140
Homologene: 19482
A830018L16Rik
Name: RIKEN cDNA A830018L16 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 320492
Homologene: 14194
Nhej1
Name: non-homologous end joining factor 1
Synonyms: 1700029B21Rik, XLF, cernunnos
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 75570
Homologene: 11714
Olfr1143
Name: olfactory receptor 1143
Synonyms: GA_x6K02T2Q125-49303473-49304405, MOR177-14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258290
Homologene: 74079
Dll4
Name: delta like canonical Notch ligand 4
Synonyms: Delta4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 54485
HGNC: HGNC:2910
Homologene: 10411
Cpxm1
Name: carboxypeptidase X 1 (M14 family)
Synonyms: Cpx-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 56264
Homologene: 10485
Fam110a
Name: family with sequence similarity 110, member A
Synonyms: 1700008J10Rik, 5430432M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 73847
Homologene: 12862
Gm1527
Name: predicted gene 1527
Synonyms: LOC385263
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 385263
Homologene: 133976
Stap1
Name: signal transducing adaptor family member 1
Synonyms: STAP-1, Brdg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56792
Homologene: 8103
Vmn2r14
Name: vomeronasal 2, receptor 14
Synonyms: EG231591
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231591
Homologene: 129606
C130050O18Rik
Name: RIKEN cDNA C130050O18 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 319772
Homologene: 138442
Vmn1r5
Name: vomeronasal 1 receptor 5
Synonyms: V1rc19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171192
Homologene: 128340
Vax2
Name: ventral anterior homeobox 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 24113
Homologene: 8048
Atg16l2
Name: autophagy related 16-like 2 (S. cerevisiae)
Synonyms: 2410118P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 73683
Homologene: 18981
Rcn2
Name: reticulocalbin 2
Synonyms: taipoxin-associated calcium binding protein 49, TCBP-49
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 26611
HGNC: HGNC:9935
Homologene: 2176
AC153874.4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Mex3d
Name: mex3 RNA binding family member D
Synonyms: Rkhd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237400
Homologene: 16890
Zc3h10
Name: zinc finger CCCH type containing 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 103284
Homologene: 13114
Rnf215
Name: ring finger protein 215
Synonyms: 0610009J22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71673
Homologene: 12402
Cdh18
Name: cadherin 18
Synonyms: B230220E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 320865
HGNC: HGNC:1757
Homologene: 55858
9130401M01Rik
Name: RIKEN cDNA 9130401M01 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 75758
Homologene: 12622
Vmn2r96
Name: vomeronasal 2, receptor 96
Synonyms: EG433070
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 433070
Casp16
Name: caspase 16, apoptosis-related cysteine peptidase
Synonyms: Gm5146, Casp16, Casp16-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 381070
Homologene: 72522
Ercc3
Name: excision repair cross-complementing rodent repair deficiency, complementation group 3
Synonyms: XPB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 13872
HGNC: HGNC:3435
Homologene: 96
Olfr1451
Name: olfactory receptor 1451
Synonyms: GA_x6K02T2RE5P-3328502-3329434, MOR202-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258700
Homologene: 128082
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 11,545,295 bp
  • A to G, chromosome 1 at 74,968,789 bp
  • A to G, chromosome 1 at 160,120,567 bp
  • A to C, chromosome 1 at 194,644,150 bp
  • C to A, chromosome 2 at 10,105,246 bp
  • A to C, chromosome 2 at 52,195,470 bp
  • T to A, chromosome 2 at 65,460,829 bp
  • T to C, chromosome 2 at 87,803,181 bp
  • T to A, chromosome 2 at 106,372,507 bp
  • G to A, chromosome 2 at 118,117,574 bp
  • C to A, chromosome 2 at 119,331,153 bp
  • T to C, chromosome 2 at 130,393,171 bp
  • C to A, chromosome 2 at 151,970,086 bp
  • A to G, chromosome 2 at 161,607,319 bp
  • T to A, chromosome 2 at 181,356,002 bp
  • T to A, chromosome 3 at 7,437,439 bp
  • T to C, chromosome 3 at 28,915,774 bp
  • C to T, chromosome 3 at 55,502,892 bp
  • T to C, chromosome 3 at 113,629,973 bp
  • A to G, chromosome 3 at 135,595,075 bp
  • G to T, chromosome 3 at 144,953,764 bp
  • T to C, chromosome 3 at 152,448,764 bp
  • A to G, chromosome 4 at 58,072,737 bp
  • T to A, chromosome 4 at 133,613,655 bp
  • A to G, chromosome 5 at 21,375,523 bp
  • T to C, chromosome 5 at 48,257,109 bp
  • A to G, chromosome 5 at 86,081,288 bp
  • A to G, chromosome 5 at 104,477,166 bp
  • G to T, chromosome 5 at 109,218,896 bp
  • G to A, chromosome 5 at 115,553,968 bp
  • G to A, chromosome 5 at 120,539,259 bp
  • G to A, chromosome 5 at 139,414,558 bp
  • A to C, chromosome 6 at 56,985,799 bp
  • T to C, chromosome 6 at 83,711,444 bp
  • T to C, chromosome 6 at 137,376,989 bp
  • T to C, chromosome 7 at 67,679,073 bp
  • A to T, chromosome 7 at 101,293,396 bp
  • A to T, chromosome 7 at 105,377,315 bp
  • A to T, chromosome 7 at 119,965,659 bp
  • C to T, chromosome 8 at 72,058,400 bp
  • C to T, chromosome 8 at 83,969,128 bp
  • C to A, chromosome 9 at 20,775,325 bp
  • G to T, chromosome 9 at 56,042,169 bp
  • A to T, chromosome 9 at 80,342,065 bp
  • A to G, chromosome 10 at 67,548,718 bp
  • A to T, chromosome 10 at 77,798,730 bp
  • G to T, chromosome 10 at 80,381,671 bp
  • C to A, chromosome 10 at 128,544,755 bp
  • A to G, chromosome 11 at 4,139,760 bp
  • A to C, chromosome 11 at 121,842,090 bp
  • T to C, chromosome 12 at 70,983,389 bp
  • C to T, chromosome 12 at 73,975,032 bp
  • T to A, chromosome 12 at 104,412,322 bp
  • A to G, chromosome 13 at 11,692,633 bp
  • T to C, chromosome 13 at 55,213,771 bp
  • T to C, chromosome 13 at 55,324,407 bp
  • G to A, chromosome 14 at 31,278,151 bp
  • T to A, chromosome 14 at 31,347,809 bp
  • A to G, chromosome 14 at 60,692,339 bp
  • T to A, chromosome 14 at 79,453,024 bp
  • T to A, chromosome 15 at 23,366,913 bp
  • A to T, chromosome 15 at 58,025,369 bp
  • T to C, chromosome 15 at 73,130,876 bp
  • A to G, chromosome 15 at 76,629,300 bp
  • G to A, chromosome 15 at 99,671,938 bp
  • A to G, chromosome 16 at 4,045,560 bp
  • C to T, chromosome 16 at 14,142,534 bp
  • G to A, chromosome 16 at 17,910,094 bp
  • G to A, chromosome 16 at 45,580,232 bp
  • T to C, chromosome 16 at 58,433,445 bp
  • T to A, chromosome 17 at 18,582,565 bp
  • T to C, chromosome 17 at 23,552,092 bp
  • A to G, chromosome 18 at 10,547,420 bp
  • T to C, chromosome 18 at 12,519,877 bp
  • G to A, chromosome 18 at 32,265,741 bp
  • G to A, chromosome 18 at 58,113,325 bp
  • T to C, chromosome 18 at 74,960,941 bp
  • T to C, chromosome 19 at 5,135,121 bp
  • T to A, chromosome 19 at 12,999,402 bp
  • T to C, chromosome 19 at 47,113,172 bp
  • A to G, chromosome 19 at 47,685,533 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0316 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038526-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.