Strain Name:
C57BL/6J-MtgxR0332Btlr/Mmmh
Stock Number:
038541-MU
Citation ID:
RRID:MMRRC_038541-MU
Other Names:
R0332 (G1), C57BL/6J-MtgxR0332Btlr
Major Collection:

Gene Information

Sulf2
Name: sulfatase 2
Synonyms: 2010004N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 72043
Homologene: 10313
Arhgef7
Name: Rho guanine nucleotide exchange factor (GEF7)
Synonyms: Cool, PIX, Pak interacting exchange factor, p85SPR, betaPix-c, betaPix-b, cool-1, betaPix
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 54126
Homologene: 2895
Aggf1
Name: angiogenic factor with G patch and FHA domains 1
Synonyms: 2310029P06Rik, VG5Q, 2010009L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 66549
Homologene: 41220
Snx2
Name: sorting nexin 2
Synonyms: 0610030A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 67804
VEGA: 18
Homologene: 2332
Eif3g
Name: eukaryotic translation initiation factor 3, subunit G
Synonyms: TU-189B2, p44, 44kDa, D0Jmb4, Eif3s4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 53356
VEGA: 9
HGNC: HGNC:3274
Homologene: 2784
Nup210l
Name: nucleoporin 210-like
Synonyms: 4930548O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 77595
Homologene: 28122
Setd3
Name: SET domain containing 3
Synonyms: 2610305M23Rik, D12Ertd771e, 2610102I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 52690
Homologene: 41748
Cstf3
Name: cleavage stimulation factor, 3' pre-RNA, subunit 3
Synonyms: 4732468G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228410
HGNC: HGNC:2485
Homologene: 1014
Zfhx3
Name: zinc finger homeobox 3
Synonyms: WBP9, A230102L03Rik, Atbf1, Sci
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11906
HGNC: HGNC:777
Homologene: 21366
Bop1
Name: block of proliferation 1
Synonyms: Erb1p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12181
VEGA: 15
Homologene: 6612
Vrk1
Name: vaccinia related kinase 1
Synonyms: 51PK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 22367
VEGA: 12
Homologene: 2541
Fto
Name: fat mass and obesity associated
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 26383
Homologene: 8053
Uhrf1bp1
Name: UHRF1 (ICBP90) binding protein 1
Synonyms: 1110020K19Rik, F830021D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224648
Homologene: 9816
Ints4
Name: integrator complex subunit 4
Synonyms: 2610034N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101861
Homologene: 69427
Ccar2
Name: cell cycle activator and apoptosis regulator 2
Synonyms: 2610301G19Rik, Dbc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219158
VEGA: 14
Homologene: 10910
Tlk1
Name: tousled-like kinase 1
Synonyms: 4930545J15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228012
Homologene: 130657
Hspb8
Name: heat shock protein 8
Synonyms: HSP20-like, HSP22, D5Ucla4, E2IG1, H11, Cryac, H11K
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 80888
Homologene: 8654
Supt16
Name: SPT16, facilitates chromatin remodeling subunit
Synonyms: Cdc68, Fact140, Spt16, Supt16h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 114741
VEGA: 14
Homologene: 5207
Rasa2
Name: RAS p21 protein activator 2
Synonyms: GAP1m, 5430433H21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 114713
HGNC: HGNC:9872
Homologene: 4745
Pikfyve
Name: phosphoinositide kinase, FYVE type zinc finger containing
Synonyms: 5230400C17Rik, Pip5k3, PipkIII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18711
Homologene: 32115
Usf2
Name: upstream transcription factor 2
Synonyms: Usf-2, bHLHb12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22282
Homologene: 2527
Dsp
Name: desmoplakin
Synonyms: DP, 2300002E22Rik, 5730453H04Rik, rul
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 109620
HGNC: HGNC:3052
Homologene: 37922
Jph4
Name: junctophilin 4
Synonyms: JPHL1, JP-4, 9330157P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 319984
Homologene: 13034
Ifitm1
Name: interferon induced transmembrane protein 1
Synonyms: fragilis2, 1110036C17Rik, Mil2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 68713
HGNC: HGNC:5412
Homologene: 135938
Atad1
Name: ATPase family, AAA domain containing 1
Synonyms: 4921525H23Rik, Thorase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 67979
VEGA: 19
Homologene: 5960
Usp37
Name: ubiquitin specific peptidase 37
Synonyms: C330008N13Rik, 4932415L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 319651
Homologene: 10858
Tmub2
Name: transmembrane and ubiquitin-like domain containing 2
Synonyms: 2010008E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 72053
Homologene: 18581
Trpm2
Name: transient receptor potential cation channel, subfamily M, member 2
Synonyms: Trrp7, LTRPC2, TRPC7, 9830168K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 28240
Homologene: 20709
Gpatch8
Name: G patch domain containing 8
Synonyms: 5430405G24Rik, Gpatc8, ENSMUSG00000075516, Fbm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237943
Homologene: 46117
Optn
Name: optineurin
Synonyms: 4930441O07Rik, TFIIIA-INTP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71648
Homologene: 11085
Wdr72
Name: WD repeat domain 72
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 546144
Homologene: 52326
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Tmprss7
Name: transmembrane serine protease 7
Synonyms: LOC385645, B230219I23Rik, matriptase-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 208171
Homologene: 18178
Loxhd1
Name: lipoxygenase homology domains 1
Synonyms: 1700096C21Rik, sba
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240411
Gm872
Name: predicted gene 872
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Nlrp2
Name: NLR family, pyrin domain containing 2
Synonyms: PYPAF2, E330007A02Rik, Nalp2, Pan1, Nbs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232827
Homologene: 56789
Slc66a1
Name: solute carrier family 66 member 1
Synonyms: Pqlc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 212555
Homologene: 56784
Plppr5
Name: phospholipid phosphatase related 5
Synonyms: Lppr5, 4833424O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 75769
Homologene: 25279
Ccdc110
Name: coiled-coil domain containing 110
Synonyms: LOC212392
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 212392
Homologene: 17668
Aox3
Name: aldehyde oxidase 3
Synonyms: AOH1, 1200011D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71724
Homologene: 90899
Zfp712
Name: zinc finger protein 712
Synonyms: 4921504N20Rik, mszf31, mszf89
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 78251
VEGA: 13
Homologene: 136296
Ppp1r36
Name: protein phosphatase 1, regulatory subunit 36
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 210762
VEGA: 12
Homologene: 52094
Mug1
Name: murinoglobulin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17836
Homologene: 136663
Phykpl
Name: 5-phosphohydroxy-L-lysine phospholyase
Synonyms: 2900006B13Rik, Agxt2l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 72947
Homologene: 75268
Dgkq
Name: diacylglycerol kinase, theta
Synonyms: 110kDa, Dagk4, DAGK7, Dgkd, Dgk theta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 110524
HGNC: HGNC:2856
Homologene: 20352
Ptgis
Name: prostaglandin I2 (prostacyclin) synthase
Synonyms: Pgi2, Pgis, Cyp8a1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19223
HGNC: HGNC:9603
Homologene: 37374
Try10
Name: trypsin 10
Synonyms: trypsinogen 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 436522
HGNC: HGNC:9475
Homologene: 134623
Ifnl2
Name: interferon lambda 2
Synonyms: EG330496, Il28a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330496
Homologene: 77540
Xrra1
Name: X-ray radiation resistance associated 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 446101
Homologene: 19547
Olfr555
Name: olfactory receptor 555
Synonyms: GA_x6K02T2PBJ9-5375442-5376389, MOR10-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259107
Homologene: 51817
Gm7579
Name: predicted gene 7579
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 105243090
Gm10644
Name: predicted gene 10644
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 100126034
VEGA: 8
Olfr18
Name: olfactory receptor 18
Synonyms: MTPCR34, MOR145-1, GA_x6K02T2PVTD-14054886-14053957
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18315
Homologene: 138313
Tbx4
Name: T-box 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 21387
Homologene: 7968
Fam228a
Name: family with sequence similarity 228, member A
Synonyms: 4930417G10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 74855
VEGA: 12
Homologene: 54902
Gcnt4
Name: glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase)
Synonyms: LOC238786, LOC218476, C2GNT3, Gm73
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218476
VEGA: 13
Homologene: 41144
Gm7275
Name: predicted gene 7275
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 639644
VEGA: 16
1520401A03Rik
Name: RIKEN cDNA 1520401A03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 320309
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 58,142,751 bp
  • A to G, chromosome 1 at 65,264,399 bp
  • A to T, chromosome 1 at 74,495,710 bp
  • C to T, chromosome 2 at 5,024,115 bp
  • A to T, chromosome 2 at 70,745,565 bp
  • A to G, chromosome 2 at 76,765,882 bp
  • A to C, chromosome 2 at 76,778,194 bp
  • G to T, chromosome 2 at 104,646,467 bp
  • G to A, chromosome 2 at 166,089,199 bp
  • A to T, chromosome 2 at 167,214,833 bp
  • G to T, chromosome 3 at 90,132,309 bp
  • A to T, chromosome 3 at 117,671,932 bp
  • C to T, chromosome 4 at 139,300,299 bp
  • T to C, chromosome 5 at 108,655,099 bp
  • T to A, chromosome 5 at 116,409,473 bp
  • T to A, chromosome 6 at 41,354,220 bp
  • G to A, chromosome 6 at 121,849,897 bp
  • C to A, chromosome 7 at 5,317,630 bp
  • T to C, chromosome 7 at 28,509,331 bp
  • T to A, chromosome 7 at 30,955,179 bp
  • T to C, chromosome 7 at 97,517,718 bp
  • T to C, chromosome 7 at 99,876,242 bp
  • A to T, chromosome 7 at 102,659,465 bp
  • T to C, chromosome 7 at 140,968,453 bp
  • T to C, chromosome 7 at 142,212,375 bp
  • T to A, chromosome 8 at 11,824,701 bp
  • G to T, chromosome 8 at 45,942,964 bp
  • A to G, chromosome 8 at 83,933,581 bp
  • A to T, chromosome 8 at 91,401,890 bp
  • T to C, chromosome 8 at 108,946,623 bp
  • A to G, chromosome 9 at 20,314,056 bp
  • A to T, chromosome 9 at 20,897,984 bp
  • A to T, chromosome 9 at 74,157,252 bp
  • A to T, chromosome 9 at 96,606,176 bp
  • A to T, chromosome 10 at 77,947,988 bp
  • C to T, chromosome 10 at 93,035,457 bp
  • A to G, chromosome 11 at 51,586,675 bp
  • A to T, chromosome 11 at 85,898,530 bp
  • G to A, chromosome 11 at 102,288,348 bp
  • T to C, chromosome 11 at 102,481,842 bp
  • T to A, chromosome 12 at 4,735,018 bp
  • T to A, chromosome 12 at 76,427,903 bp
  • G to C, chromosome 12 at 106,058,625 bp
  • T to C, chromosome 12 at 108,107,579 bp
  • T to A, chromosome 13 at 38,182,228 bp
  • T to A, chromosome 13 at 67,040,813 bp
  • T to C, chromosome 13 at 95,369,446 bp
  • G to T, chromosome 13 at 96,946,510 bp
  • A to T, chromosome 14 at 52,181,157 bp
  • T to C, chromosome 14 at 55,114,010 bp
  • G to T, chromosome 14 at 70,141,935 bp
  • A to G, chromosome 15 at 76,455,987 bp
  • C to T, chromosome 16 at 45,680,638 bp
  • A to T, chromosome 16 at 48,073,769 bp
  • A to T, chromosome 17 at 23,714,604 bp
  • T to C, chromosome 17 at 27,893,294 bp
  • T to C, chromosome 18 at 53,212,911 bp
  • T to A, chromosome 18 at 77,383,830 bp
  • A to G, chromosome 19 at 32,702,534 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0332 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038541-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.