Strain Name:
C57BL/6J-MtgxR0346Btlr/Mmmh
Stock Number:
038553-MU
Citation ID:
RRID:MMRRC_038553-MU
Other Names:
R0346 (G1), C57BL/6J-MtgxR0346Btlr
Major Collection:

Strain Information

Rnf145
Name: ring finger protein 145
Synonyms: 3732413I11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74315
Homologene: 14427
Pum1
Name: pumilio RNA-binding family member 1
Synonyms: Pumm
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 80912
Homologene: 22830
Nup210l
Name: nucleoporin 210-like
Synonyms: 4930548O11Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 77595
Homologene: 28122
Tbcel
Name: tubulin folding cofactor E-like
Synonyms: E130107N23Rik, Lrrc35
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 272589
Homologene: 16120
Hap1
Name: huntingtin-associated protein 1
Synonyms: HAP-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 15114
HGNC: HGNC:4812
Homologene: 2935
Washc2
Name: WASH complex subunit 2
Synonyms: Fam21, D6Wsu116e, C530005J20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 28006
Homologene: 41686
Etl4
Name: enhancer trap locus 4
Synonyms: Sickle tail, 6620402G01Rik, Skt, 9430077C05Rik, Etl-4, E330027G05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 208618
Homologene: 10477
Ap3b1
Name: adaptor-related protein complex 3, beta 1 subunit
Synonyms: AP-3, Hps2, beta3A, recombination induced mutation 2, rim2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 11774
VEGA: 13
HGNC: HGNC:566
Homologene: 68125
Fbxo15
Name: F-box protein 15
Synonyms: Fbx15, ecat3
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 50764
VEGA: 18
Homologene: 17644
Nav2
Name: neuron navigator 2
Synonyms: Rainb1, POMFIL2, Unc53H2, 5330421F07Rik, HELAD1, RAINB2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 78286
Homologene: 52330
Ccdc191
Name: coiled-coil domain containing 191
Synonyms: 2610015P09Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 212153
Homologene: 19484
Cep85
Name: centrosomal protein 85
Synonyms: Ccdc21, 2410030J07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 70012
Homologene: 11254
Rif1
Name: replication timing regulatory factor 1
Synonyms: 5730435J01Rik, D2Ertd145e, 6530403D07Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 51869
Homologene: 41231
Alkbh5
Name: alkB homolog 5, RNA demethylase
Synonyms: Ofoxd, Abh5
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268420
Homologene: 9818
Plekhg5
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 5
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 269608
Homologene: 10768
Vps18
Name: VPS18 CORVET/HOPS core subunit
Synonyms: 9930024E13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228545
Homologene: 13302
Islr2
Name: immunoglobulin superfamily containing leucine-rich repeat 2
Synonyms: Linx, mbu-3, B930052A04Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320563
VEGA: 9
Homologene: 10833
Bcl2
Name: B cell leukemia/lymphoma 2
Synonyms: C430015F12Rik, Bcl-2, D830018M01Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12043
HGNC: HGNC:990
Homologene: 527
Kif26a
Name: kinesin family member 26A
Synonyms: N-11 kinesin
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 668303
Homologene: 18970
Camta1
Name: calmodulin binding transcription activator 1
Synonyms: 1810059M14Rik, 2310058O09Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100072
Homologene: 18942
Ass1
Name: argininosuccinate synthetase 1
Synonyms: fold, ASS, Ass-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11898
HGNC: HGNC:758
Homologene: 6899
Cttn
Name: cortactin
Synonyms: Ems1, 1110020L01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13043
HGNC: HGNC:3338
Homologene: 3834
Rps6
Name: ribosomal protein S6
Synonyms: S6R
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 20104
Homologene: 85949
Add3
Name: adducin 3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 27360
VEGA: 19
HGNC: HGNC:245
Homologene: 40893
Trpv4
Name: transient receptor potential cation channel, subfamily V, member 4
Synonyms: VR-OAC, VRL-2, VROAC, Trp12, OTRPC4, 0610033B08Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 63873
Homologene: 11003
AU021092
Name: expressed sequence AU021092
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239691
Homologene: 17587
Alas1
Name: aminolevulinic acid synthase 1
Synonyms: succinyl-CoA: glycine C-succinyl transferase, Alas-1, 5-aminolevulinate synthase, ALAS-N
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 11655
HGNC: HGNC:396
Homologene: 55478
Rpl6
Name: ribosomal protein L6
Synonyms: Taxreb107
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19988
Homologene: 31001
Kif13a
Name: kinesin family member 13A
Synonyms: 4930505I07Rik, N-3 kinesin
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 16553
VEGA: 13
Homologene: 22589
Nipbl
Name: NIPBL cohesin loading factor
Synonyms: 4933421G18Rik, 4921518A06Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 71175
VEGA: 15
Homologene: 15850
Dedd2
Name: death effector domain-containing DNA binding protein 2
Synonyms: 2410050E11Rik, FLAME-3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67379
Homologene: 23569
Inpp5f
Name: inositol polyphosphate-5-phosphatase F
Synonyms: SAC2, 5830435P03Rik, cI-27
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101490
Homologene: 8962
Vps13a
Name: vacuolar protein sorting 13A
Synonyms: 4930543C13Rik, D330038K10Rik, 4930516E05Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 271564
VEGA: 19
HGNC: HGNC:1908
Homologene: 22068
Smcr8
Name: Smith-Magenis syndrome chromosome region, candidate 8 homolog (human)
Synonyms: D030073L15Rik, 2310076G09Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237782
Homologene: 16989
Prss35
Name: serine protease 35
Synonyms: 6030424L22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244954
Homologene: 17734
Abca16
Name: ATP-binding cassette, sub-family A member 16
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233810
Homologene: 132942
Clvs2
Name: clavesin 2
Synonyms: Rlbp1l2, A330019N05Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215890
Homologene: 27894
Ryr1
Name: ryanodine receptor 1, skeletal muscle
Synonyms: Ryr, skrr, calcium release channel isoform 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20190
Homologene: 68069
Syk
Name: spleen tyrosine kinase
Synonyms: Sykb
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20963
Homologene: 2390
Abca13
Name: ATP-binding cassette, sub-family A member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268379
Homologene: 27991
Dppa4
Name: developmental pluripotency associated 4
Synonyms: ECAT15-1, 2410091M23Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 73693
VEGA: 16
Homologene: 130462
Slc35d1
Name: solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
Synonyms: UGTREL7
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242585
Homologene: 22870
Trim16
Name: tripartite motif-containing 16
Synonyms: EBBP, 9130006M08Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 94092
Homologene: 4726
Mroh4
Name: maestro heat-like repeat family member 4
Synonyms: 1700016M24Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 69439
Homologene: 72545
Ptafr
Name: platelet-activating factor receptor
Synonyms: PAFR, PAF receptor
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 19204
HGNC: HGNC:9582
Homologene: 20260
Cntn1
Name: contactin 1
Synonyms: usl, F3cam, CNTN
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12805
HGNC: HGNC:2171
Homologene: 7274
Nlrp9b
Name: NLR family, pyrin domain containing 9B
Synonyms: Nalp9b, Nalp-delta
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243874
Homologene: 18530
Lrrd1
Name: leucine rich repeats and death domain containing 1
Synonyms: 4932412H11Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 242838
Homologene: 18247
Mybph
Name: myosin binding protein H
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 53311
HGNC: HGNC:7552
Homologene: 3661
Myo1h
Name: myosin 1H
Synonyms: 4631401O15Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231646
Homologene: 82639
Vars2
Name: valyl-tRNA synthetase 2, mitochondrial
Synonyms: 1190004I24Rik, Vars2l
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 68915
Homologene: 57502
Myh4
Name: myosin, heavy polypeptide 4, skeletal muscle
Synonyms: MyHC-IIb, Myhsf, MHC2B, Minmus, MYH-2B, Minimsc, MM
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17884
HGNC: HGNC:7574
Homologene: 123880
Kif14
Name: kinesin family member 14
Synonyms: N-3 kinesin, D1Ertd367e
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381293
Homologene: 8916
Ccng2
Name: cyclin G2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12452
HGNC: HGNC:1593
Homologene: 3208
Itgav
Name: integrin alpha V
Synonyms: vitronectin receptor alpha polypeptide (VNRA), 1110004F14Rik, alphav-integrin, 2610028E01Rik, CD51, D430040G12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16410
HGNC: HGNC:6150
Homologene: 20510
Gm7647
Name: predicted gene 7647
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 108169099
Msh5
Name: mutS homolog 5
Synonyms: Mut5, G7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17687
HGNC: HGNC:7328
Homologene: 8415
Or6c8b
Name: olfactory receptor family 6 subfamily C member 8B
Synonyms: GA_x6K02T2PULF-10732607-10731678, Olfr765, MOR115-4
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 544748
Homologene: 105186
Or7e178
Name: olfactory receptor family 7 subfamily E member 178
Synonyms: MTPCR34, Olfr18, GA_x6K02T2PVTD-14054886-14053957, MOR145-1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18315
HGNC: HGNC:8396
Homologene: 138313
Tsga10
Name: testis specific 10
Synonyms: Mtsga10, 4933432N21Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 211484
Homologene: 23531
P2ry13
Name: purinergic receptor P2Y, G-protein coupled 13
Synonyms: Gpr86, P2Y13, SP174, 2010001L06Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74191
HGNC: HGNC:4537
Homologene: 12543
Eif2b4
Name: eukaryotic translation initiation factor 2B, subunit 4 delta
Synonyms: Eif2b
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13667
HGNC: HGNC:3260
Homologene: 5976
Gm9970
Name: predicted gene 9970
Type: Gene
Species: Mouse
Chromosome: 5
Caln1
Name: calneuron 1
Synonyms: 9630012C17Rik, Cabp8
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 140904
Homologene: 10966
Ift56
Name: intraflagellar transport 56
Synonyms: hydrocephalic-polydactyl, hop, hpy, Ttc26, 9430097H08Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 264134
Homologene: 11786
Vmn1r72
Name: vomeronasal 1 receptor 72
Synonyms: V1rg1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 252905
Homologene: 74318
Dnajb13
Name: DnaJ heat shock protein family (Hsp40) member B13
Synonyms: 1700014P03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69387
Homologene: 70141
Irag1
Name: inositol 1,4,5-triphosphate receptor associated 1
Synonyms: Ris1, Mrvi1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17540
HGNC: HGNC:7237
Homologene: 4425
Or1e26
Name: olfactory receptor family 1 subfamily E member 26
Synonyms: GA_x6K02T2P1NL-3760313-3759375, Olfr385, MOR135-3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 259025
Homologene: 133670
Spata31e4
Name: spermatogenesis associated 31 subfamily E member 4
Synonyms: Gm8765
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 667693
Homologene: 134512
Ear2
Name: eosinophil-associated, ribonuclease A family, member 2
Synonyms: eosinophil-derived neurotoxin, liver, Rnase2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 13587
Homologene: 40596
Scel
Name: sciellin
Synonyms: 9230114I02Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 64929
VEGA: 14
Homologene: 2850
Tob2
Name: transducer of ERBB2, 2
Synonyms: 4930545K18Rik, 2900090N22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 57259
VEGA: 15
Homologene: 9447
Hgd
Name: homogentisate 1, 2-dioxygenase
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 15233
HGNC: HGNC:4892
Homologene: 156
Zfp763
Name: zinc finger protein 763
Synonyms: 1700065O13Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 73451
Homologene: 66274
1700018A14Rik
Name: RIKEN cDNA 1700018A14 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Or4z4
Name: olfactory receptor family 4 subfamily Z member 4
Synonyms: Olfr1427, GA_x6K02T2RE5P-2458473-2457538, MOR239-4
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258674
Homologene: 128080
Sfxn4
Name: sideroflexin 4
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 94281
Homologene: 14228
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 37,840,519 bp
  • G to A, chromosome 1 at 106,712,562 bp
  • T to G, chromosome 1 at 134,197,754 bp
  • T to A, chromosome 1 at 136,468,160 bp
  • G to T, chromosome 2 at 20,759,652 bp
  • A to T, chromosome 2 at 31,514,819 bp
  • GCCACCA to GCCA, chromosome 2 at 52,110,324 bp
  • G to T, chromosome 2 at 83,792,609 bp
  • A to G, chromosome 2 at 119,297,164 bp
  • T to C, chromosome 3 at 59,209,566 bp
  • T to A, chromosome 3 at 90,189,438 bp
  • T to C, chromosome 4 at 86,855,981 bp
  • A to C, chromosome 4 at 103,190,847 bp
  • A to T, chromosome 4 at 130,779,805 bp
  • T to A, chromosome 4 at 132,580,079 bp
  • A to T, chromosome 4 at 134,132,422 bp
  • C to A, chromosome 4 at 151,075,140 bp
  • T to C, chromosome 4 at 152,114,253 bp
  • C to A, chromosome 5 at 3,850,215 bp
  • A to G, chromosome 5 at 31,188,108 bp
  • A to G, chromosome 5 at 31,240,838 bp
  • T to G, chromosome 5 at 93,270,894 bp
  • T to C, chromosome 5 at 94,962,980 bp
  • A to T, chromosome 5 at 114,355,209 bp
  • C to A, chromosome 5 at 114,630,529 bp
  • A to T, chromosome 5 at 121,208,491 bp
  • C to A, chromosome 5 at 130,822,921 bp
  • T to C, chromosome 6 at 38,409,435 bp
  • T to C, chromosome 6 at 116,220,523 bp
  • C to A, chromosome 7 at 11,669,694 bp
  • T to C, chromosome 7 at 20,024,515 bp
  • T to C, chromosome 7 at 25,211,269 bp
  • G to T, chromosome 7 at 29,067,588 bp
  • C to A, chromosome 7 at 49,604,585 bp
  • T to C, chromosome 7 at 100,503,925 bp
  • T to C, chromosome 7 at 110,898,976 bp
  • T to A, chromosome 7 at 120,435,932 bp
  • T to A, chromosome 7 at 128,690,668 bp
  • A to T, chromosome 7 at 144,452,539 bp
  • A to G, chromosome 9 at 20,314,411 bp
  • A to T, chromosome 9 at 42,437,243 bp
  • G to A, chromosome 9 at 58,198,343 bp
  • A to G, chromosome 9 at 86,755,351 bp
  • A to T, chromosome 9 at 106,243,351 bp
  • G to C, chromosome 10 at 33,622,546 bp
  • C to A, chromosome 10 at 129,046,473 bp
  • A to T, chromosome 11 at 9,566,278 bp
  • A to G, chromosome 11 at 44,555,164 bp
  • C to G, chromosome 11 at 60,538,741 bp
  • A to G, chromosome 11 at 60,779,750 bp
  • A to G, chromosome 11 at 62,840,694 bp
  • A to T, chromosome 11 at 67,260,326 bp
  • A to G, chromosome 11 at 73,589,457 bp
  • A to G, chromosome 11 at 100,356,029 bp
  • G to T, chromosome 12 at 112,179,348 bp
  • T to A, chromosome 13 at 46,814,219 bp
  • T to C, chromosome 13 at 50,703,310 bp
  • G to A, chromosome 13 at 52,640,659 bp
  • A to T, chromosome 13 at 94,445,971 bp
  • A to G, chromosome 14 at 44,102,906 bp
  • A to T, chromosome 14 at 103,529,984 bp
  • T to G, chromosome 15 at 8,360,956 bp
  • G to C, chromosome 15 at 74,614,292 bp
  • C to A, chromosome 15 at 81,858,223 bp
  • G to T, chromosome 15 at 92,232,087 bp
  • T to C, chromosome 16 at 5,216,854 bp
  • C to T, chromosome 16 at 37,588,774 bp
  • T to C, chromosome 16 at 43,938,952 bp
  • T to A, chromosome 16 at 48,289,324 bp
  • A to T, chromosome 17 at 33,019,747 bp
  • A to G, chromosome 17 at 35,029,888 bp
  • A to T, chromosome 17 at 35,664,864 bp
  • T to C, chromosome 18 at 46,199,709 bp
  • T to A, chromosome 18 at 84,960,221 bp
  • A to T, chromosome 19 at 12,099,439 bp
  • T to A, chromosome 19 at 16,677,969 bp
  • C to T, chromosome 19 at 53,216,956 bp
  • A to T, chromosome 19 at 60,858,673 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0346 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038553-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.