Strain Name:
C57BL/6J-MtgxR0384Btlr/Mmmh
Stock Number:
038590-MU
Citation ID:
RRID:MMRRC_038590-MU
Other Names:
R0384 (G1), C57BL/6J-MtgxR0384Btlr
Major Collection:

Gene Information

Npr1
Name: natriuretic peptide receptor 1
Synonyms: NPR-A, GC-A, NPRA, guanylyl cyclase-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 18160
HGNC: HGNC:7943
Homologene: 37367
Sema3b
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
Synonyms: Semaa, sema5, SemA, LUCA-1, SemA, semaV
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20347
Homologene: 20972
Cyp19a1
Name: cytochrome P450, family 19, subfamily a, polypeptide 1
Synonyms: aromatase, ArKO, Cyp19, Int5, Ar, Int-5, p450arom
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 13075
VEGA: 9
HGNC: HGNC:2594
Homologene: 30955
Phf14
Name: PHD finger protein 14
Synonyms: 5730446A07Rik, 1110001C23Rik, 4932409F11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 75725
Homologene: 8775
Tnpo3
Name: transportin 3
Synonyms: C430013M08Rik, D6Ertd313e, 5730544L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 320938
Homologene: 40848
Slc25a13
Name: solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
Synonyms: citrin, Ctrn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 50799
Homologene: 22800
Ncaph2
Name: non-SMC condensin II complex, subunit H2
Synonyms: Kleisin beta, 2610524G04Rik, D15Ertd785e, 0610010J20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 52683
Homologene: 12045
Prdm2
Name: PR domain containing 2, with ZNF domain
Synonyms: 4833427P12Rik, LOC381568, E330024L24Rik, Riz, KMT8, Riz1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 110593
HGNC: HGNC:9347
Homologene: 40822
Map4
Name: microtubule-associated protein 4
Synonyms: Mtap4, MAP 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 17758
HGNC: HGNC:6862
Homologene: 1780
Eefsec
Name: eukaryotic elongation factor, selenocysteine-tRNA-specific
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 65967
Homologene: 11073
Psmd12
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
Synonyms: P55, 1500002F15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 66997
HGNC: HGNC:9557
Homologene: 2109
Fer
Name: fer (fms/fps related) protein kinase
Synonyms: Fert2, C330004K01Rik, Fert
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 14158
VEGA: 17
HGNC: HGNC:3655
Homologene: 74300
Herc1
Name: HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Synonyms: D130015N03Rik, 2810449H11Rik, tbl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235439
HGNC: HGNC:4867
Homologene: 31207
Rif1
Name: replication timing regulatory factor 1
Synonyms: D2Ertd145e, 6530403D07Rik, 5730435J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 51869
Homologene: 41231
Atp13a1
Name: ATPase type 13A1
Synonyms: catp, Cgi152, Atp13a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 170759
VEGA: 8
Homologene: 5791
Adam8
Name: a disintegrin and metallopeptidase domain 8
Synonyms: CD156, MS2, E430039A18Rik, CD156a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11501
HGNC: HGNC:215
Homologene: 74384
Fam204a
Name: family with sequence similarity 204, member A
Synonyms: 2310065H12Rik, 2610015K05Rik, D19Ertd737e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 76539
VEGA: 19
Homologene: 41463
Ccdc141
Name: coiled-coil domain containing 141
Synonyms: 2610301F02Rik, CAMDI, ENSMUSG00000075261
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 545428
Homologene: 52149
Vps8
Name: VPS8 CORVET complex subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 209018
Homologene: 44592
Dcps
Name: decapping enzyme, scavenger
Synonyms: 1700001E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 69305
Homologene: 32202
Dnmt3l
Name: DNA (cytosine-5-)-methyltransferase 3-like
Synonyms: D6Ertd14e, ecat7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 54427
HGNC: HGNC:2980
Homologene: 8362
A830010M20Rik
Name: RIKEN cDNA A830010M20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231570
VEGA: 5
Homologene: 128318
Dnhd1
Name: dynein heavy chain domain 1
Synonyms: 8030491N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 77505
Homologene: 131117
Dnajc6
Name: DnaJ heat shock protein family (Hsp40) member C6
Synonyms: 2810027M23Rik, auxilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 72685
Homologene: 8865
Idh2
Name: isocitrate dehydrogenase 2 (NADP+), mitochondrial
Synonyms: Idh-2, IDPm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 269951
HGNC: HGNC:5383
Homologene: 37590
Muc5ac
Name: mucin 5, subtypes A and C, tracheobronchial/gastric
Synonyms: MGM, 2210005L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 17833
HGNC: HGNC:7515
Homologene: 137237
Tmem138
Name: transmembrane protein 138
Synonyms: 2900055D14Rik, 1700113I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 72982
VEGA: 19
Homologene: 9518
Fat2
Name: FAT atypical cadherin 2
Synonyms: Fath2, mKIAA0811, LOC245827, EMI2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Ugcg
Name: UDP-glucose ceramide glucosyltransferase
Synonyms: Ugcgl, Epcs21, GlcT-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 22234
Homologene: 37763
Fhad1
Name: forkhead-associated (FHA) phosphopeptide binding domain 1
Synonyms: 2900090M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 329977
Homologene: 77947
Dock3
Name: dedicator of cyto-kinesis 3
Synonyms: Moca, PBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 208869
HGNC: HGNC:2989
Homologene: 21030
Relt
Name: RELT tumor necrosis factor receptor
Synonyms: Tnfrsf19l, E430021K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 320100
Homologene: 13151
Cyp2j9
Name: cytochrome P450, family 2, subfamily j, polypeptide 9
Synonyms: 8430417E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 74519
Homologene: 137388
Pnpla5
Name: patatin-like phospholipase domain containing 5
Synonyms: 4833426H19Rik, GS2L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 75772
VEGA: 15
Homologene: 13376
Msto1
Name: misato 1, mitochondrial distribution and morphology regulator
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229524
Homologene: 41228
Nat8f2
Name: N-acetyltransferase 8 (GCN5-related) family member 2
Synonyms: Cml2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 93673
Gm5155
Name: predicted gene 5155
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381852
Homologene: 115938
Ttc41
Name: tetratricopeptide repeat domain 41
Synonyms: BC030307, Gnn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 103220
VEGA: 10
Homologene: 52968
Nwd2
Name: NACHT and WD repeat domain containing 2
Synonyms: B830017A01Rik, 3110047P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 319807
Homologene: 14974
Nrxn1
Name: neurexin I
Synonyms: neurexin I beta, neurexin I beta, neurexin I alpha, neurexin I alpha, A230068P09Rik, 1700062G21Rik, neurexin I alpha, neurexin I beta, alpha-latrotoxin receptor (calcium-dependent), 9330127H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 18189
HGNC: HGNC:8008
Homologene: 21005
Vmn2r27
Name: vomeronasal 2, receptor27
Synonyms: EG232367
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232367
Klk1b21
Name: kallikrein 1-related peptidase b21
Synonyms: Klk21, mGk-21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 16616
HGNC: HGNC:6364
Homologene: 68141
Col20a1
Name: collagen, type XX, alpha 1
Synonyms: 1700051I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 73368
Homologene: 75138
Bmp2k
Name: BMP2 inducible kinase
Synonyms: 4933417M22Rik, BIKE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 140780
Homologene: 34134
Scg2
Name: secretogranin II
Synonyms: SgII, Chgc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 20254
Homologene: 2591
Matn1
Name: matrilin 1, cartilage matrix protein
Synonyms: Mat1, CMP, matrilin-1, Crtm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 17180
HGNC: HGNC:6907
Homologene: 1783
Itga2b
Name: integrin alpha 2b
Synonyms: GP IIb, CD41, platelet glycoprotein IIb, GpIIb, alphaIIb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16399
HGNC: HGNC:6138
Homologene: 37304
Vmn1r184
Name: vomeronasal 1 receptor, 184
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100312477
Homologene: 74353
Akr1b8
Name: aldo-keto reductase family 1, member B8
Synonyms: Fgfrp, Fgrp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 14187
Homologene: 116462
Mpv17l
Name: Mpv17 transgene, kidney disease mutant-like
Synonyms: M-LP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 93734
Homologene: 13547
Nid1
Name: nidogen 1
Synonyms: nidogen-1, entactin-1, entactin 1, entactin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 18073
VEGA: 13
HGNC: HGNC:7821
Homologene: 1878
Olfr1076
Name: olfactory receptor 1076
Synonyms: MOR189-2, GA_x6K02T2Q125-47993761-47994702
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258401
Homologene: 17233
Vmn2r87
Name: vomeronasal 2, receptor 87
Synonyms: EG625131
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 625131
Homologene: 129606
Kndc1
Name: kinase non-catalytic C-lobe domain (KIND) containing 1
Synonyms: very-kind, 2410012C07Rik, B830014K08Rik, VKIND
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 76484
Homologene: 45138
Mindy4
Name: MINDY lysine 48 deubiquitinase 4
Synonyms: C330043M08Rik, LOC384387, Fam188b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 330323
Homologene: 49991
AC110527.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
Fbh1
Name: F-box DNA helicase 1
Synonyms: Fbxo18, Fbx18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 50755
Homologene: 9272
Fkbp7
Name: FK506 binding protein 7
Synonyms: FKBP23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 14231
HGNC: HGNC:3723
Homologene: 22568
Olfr1228
Name: olfactory receptor 1228
Synonyms: MOR233-1, GA_x6K02T2Q125-50696209-50695274
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258973
Homologene: 74217
Fjx1
Name: four jointed box 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 14221
Homologene: 7717
Fam98b
Name: family with sequence similarity 98, member B
Synonyms: 2610510H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 68215
Homologene: 72241
Sun5
Name: Sad1 and UNC84 domain containing 5
Synonyms: Spag4l, 1700021O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 76407
Homologene: 12640
Crabp2
Name: cellular retinoic acid binding protein II
Synonyms: CrabpII, Crabp-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 12904
HGNC: HGNC:2339
Homologene: 1415
Arhgef39
Name: Rho guanine nucleotide exchange factor (GEF) 39
Synonyms: E130306D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230098
Homologene: 19225
Musk
Name: muscle, skeletal, receptor tyrosine kinase
Synonyms: MDK4, Nsk1, Nsk3, Nsk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 18198
HGNC: HGNC:7525
Homologene: 4084
Tex52
Name: testis expressed 52
Synonyms: 4933413G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 71149
Homologene: 130761
Hook3
Name: hook microtubule tethering protein 3
Synonyms: E330005F07Rik, 5830454D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 320191
Homologene: 13022
Ky
Name: kyphoscoliosis peptidase
Synonyms: D9Mgc44e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 16716
Homologene: 11506
Olfr787
Name: olfactory receptor 787
Synonyms: MOR111-10, GA_x6K02T2PULF-11141498-11142436
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258069
Homologene: 105326
Tspoap1
Name: TSPO associated protein 1
Synonyms: Bzrap1, peripheral
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 207777
Homologene: 37961
Olfr55
Name: olfactory receptor 55
Synonyms: MOR267-17, GA_x6K02T2MG8L-16493-15546, IF6, MOR267-20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 100038859
HGNC: HGNC:8172
Homologene: 110515
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 79,435,549 bp
  • T to C, chromosome 1 at 141,257,085 bp
  • A to G, chromosome 2 at 11,749,578 bp
  • GCCACCA to GCCA, chromosome 2 at 52,110,324 bp
  • T to A, chromosome 2 at 76,665,824 bp
  • A to G, chromosome 2 at 77,027,648 bp
  • T to A, chromosome 2 at 86,509,383 bp
  • A to G, chromosome 2 at 89,249,070 bp
  • C to A, chromosome 2 at 102,451,107 bp
  • T to C, chromosome 2 at 117,267,847 bp
  • C to T, chromosome 2 at 153,858,965 bp
  • T to C, chromosome 2 at 180,999,162 bp
  • T to C, chromosome 3 at 87,953,021 bp
  • G to A, chromosome 3 at 88,910,339 bp
  • C to A, chromosome 3 at 90,465,167 bp
  • A to G, chromosome 4 at 43,498,613 bp
  • T to C, chromosome 4 at 58,373,711 bp
  • T to A, chromosome 4 at 59,220,387 bp
  • T to C, chromosome 4 at 96,585,885 bp
  • C to T, chromosome 4 at 101,598,956 bp
  • T to C, chromosome 4 at 130,944,476 bp
  • T to A, chromosome 4 at 142,002,426 bp
  • T to C, chromosome 4 at 143,135,688 bp
  • T to C, chromosome 5 at 63,805,682 bp
  • T to A, chromosome 5 at 97,031,125 bp
  • T to A, chromosome 5 at 107,508,798 bp
  • A to T, chromosome 6 at 6,042,600 bp
  • A to G, chromosome 6 at 11,997,020 bp
  • A to G, chromosome 6 at 29,582,164 bp
  • T to C, chromosome 6 at 34,364,330 bp
  • G to A, chromosome 6 at 55,216,684 bp
  • T to C, chromosome 6 at 85,868,368 bp
  • A to G, chromosome 6 at 88,281,650 bp
  • A to G, chromosome 6 at 124,223,912 bp
  • A to G, chromosome 6 at 128,379,533 bp
  • C to T, chromosome 7 at 17,915,544 bp
  • T to C, chromosome 7 at 26,267,651 bp
  • T to C, chromosome 7 at 44,105,493 bp
  • C to T, chromosome 7 at 80,098,257 bp
  • T to C, chromosome 7 at 100,847,505 bp
  • T to G, chromosome 7 at 105,720,114 bp
  • A to T, chromosome 7 at 139,910,599 bp
  • T to A, chromosome 7 at 139,986,812 bp
  • A to G, chromosome 7 at 141,812,251 bp
  • C to T, chromosome 8 at 26,044,235 bp
  • A to T, chromosome 8 at 69,797,324 bp
  • T to C, chromosome 9 at 35,175,943 bp
  • T to C, chromosome 9 at 54,172,741 bp
  • T to A, chromosome 9 at 66,481,050 bp
  • C to T, chromosome 9 at 102,542,090 bp
  • A to G, chromosome 9 at 106,901,895 bp
  • G to A, chromosome 9 at 107,600,966 bp
  • C to T, chromosome 9 at 110,034,628 bp
  • A to T, chromosome 10 at 78,052,737 bp
  • T to C, chromosome 10 at 86,763,947 bp
  • T to A, chromosome 10 at 129,463,040 bp
  • T to A, chromosome 10 at 130,471,843 bp
  • A to T, chromosome 11 at 55,269,465 bp
  • A to T, chromosome 11 at 87,766,454 bp
  • A to T, chromosome 11 at 102,465,362 bp
  • T to C, chromosome 11 at 107,485,721 bp
  • A to G, chromosome 13 at 13,463,836 bp
  • G to T, chromosome 15 at 84,120,719 bp
  • T to A, chromosome 15 at 89,369,391 bp
  • A to T, chromosome 16 at 13,940,999 bp
  • T to A, chromosome 16 at 21,506,825 bp
  • A to G, chromosome 17 at 33,176,548 bp
  • T to C, chromosome 17 at 63,924,184 bp
  • G to A, chromosome 17 at 90,208,347 bp
  • A to G, chromosome 19 at 10,574,822 bp
  • T to C, chromosome 19 at 60,221,296 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0384 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038590-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.