Strain Name:
C57BL/6J-MtgxR0393Btlr/Mmmh
Stock Number:
038599-MU
Citation ID:
RRID:MMRRC_038599-MU
Other Names:
R0393 (G1), C57BL/6J-MtgxR0393Btlr
Major Collection:

Gene Information

Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Crym
Name: crystallin, mu
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12971
HGNC: HGNC:2418
Homologene: 1424
Ppp1r13b
Name: protein phosphatase 1, regulatory subunit 13B
Synonyms: ASPP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 21981
VEGA: 12
Homologene: 9090
L3mbtl2
Name: L3MBTL2 polycomb repressive complex 1 subunit
Synonyms: 4732493N06Rik, m4mbt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 214669
Homologene: 12882
Mybl2
Name: myeloblastosis oncogene-like 2
Synonyms: Bmyb, B-Myb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17865
HGNC: HGNC:7548
Homologene: 1847
Mif
Name: macrophage migration inhibitory factor (glycosylation-inhibiting factor)
Synonyms: Glif
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 17319
VEGA: 10
HGNC: HGNC:7097
Homologene: 55655
Ubr1
Name: ubiquitin protein ligase E3 component n-recognin 1
Synonyms: E3 alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22222
Homologene: 7582
Bicd2
Name: BICD cargo adaptor 2
Synonyms: 0610027D24Rik, 1110005D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 76895
VEGA: 13
Homologene: 9070
Mlh3
Name: mutL homolog 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217716
VEGA: 12
HGNC: HGNC:7128
Homologene: 91153
Zbtb40
Name: zinc finger and BTB domain containing 40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230848
Homologene: 8912
Thbs1
Name: thrombospondin 1
Synonyms: TSP1, TSP-1, Thbs-1, tbsp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 21825
Homologene: 31142
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: A930005E13Rik, LOC381562, D930005K06Rik, 1810009A16Rik, Zubr1, p600
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69116
Homologene: 10804
Ankrd10
Name: ankyrin repeat domain 10
Synonyms: 4833425P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102334
Homologene: 9768
Lmo7
Name: LIM domain only 7
Synonyms: LOC380928, FBXO20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 380928
HGNC: HGNC:6646
Homologene: 83924
Atp13a5
Name: ATPase type 13A5
Synonyms: C630015F21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 268878
Homologene: 77451
Fbln1
Name: fibulin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 14114
HGNC: HGNC:3600
Homologene: 21295
Plod1
Name: procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
Synonyms: lysyl hydroxylase 1, LH1, 2410042F05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18822
HGNC: HGNC:9081
Homologene: 256
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, P1-Loop, Dnahc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Baz1a
Name: bromodomain adjacent to zinc finger domain 1A
Synonyms: Gtl5, Wcrf180, Acf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217578
HGNC: HGNC:960
Homologene: 45654
Trpm6
Name: transient receptor potential cation channel, subfamily M, member 6
Synonyms: CHAK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225997
VEGA: 19
Homologene: 9767
Cd180
Name: CD180 antigen
Synonyms: RP105, Ly78
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17079
HGNC: HGNC:6726
Homologene: 4077
Slc4a8
Name: solute carrier family 4 (anion exchanger), member 8
Synonyms: sodium bicarbonate cotransporter isoform 3 kNBC-3, KNBC-3, NDCBE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 59033
Homologene: 68419
Myh8
Name: myosin, heavy polypeptide 8, skeletal muscle, perinatal
Synonyms: MyHC-pn, Myhs-p, Myhsp, 4832426G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17885
HGNC: HGNC:7578
Homologene: 68256
Cyp2b10
Name: cytochrome P450, family 2, subfamily b, polypeptide 10
Synonyms: p16, Cyp2b, phenobarbitol inducible, type b, Cyp2b20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13088
HGNC: HGNC:2615
Homologene: 73894
Abcc9
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 9
Synonyms: SUR2B, SUR2A, Sur2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 20928
HGNC: HGNC:60
Homologene: 56521
Mug1
Name: murinoglobulin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17836
Homologene: 136663
Kif14
Name: kinesin family member 14
Synonyms: N-3 kinesin, D1Ertd367e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381293
Homologene: 8916
Speg
Name: SPEG complex locus
Synonyms: BPEG, SPEGbeta, SPEGalpha, D1Bwg1450e, SPEG, Apeg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 11790
Homologene: 55619
Mapkbp1
Name: mitogen-activated protein kinase binding protein 1
Synonyms: Jnkbp1, 2810483F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 26390
Homologene: 69109
Vmn2r13
Name: vomeronasal 2, receptor 13
Synonyms: Gm4867
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231589
Homologene: 129606
Ces1d
Name: carboxylesterase 1D
Synonyms: TGH, Ces3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 104158
HGNC: HGNC:1863
Homologene: 35606
Tll2
Name: tolloid-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 24087
VEGA: 19
Homologene: 56545
AC149051.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Vmn2r91
Name: vomeronasal 2, receptor 91
Synonyms: EG665210
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 665210
Homologene: 115024
Olfr1155
Name: olfactory receptor 1155
Synonyms: GA_x6K02T2Q125-49426894-49425950, MOR174-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258636
Homologene: 133739
Spock1
Name: sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1
Synonyms: testican 1, Ticn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20745
Homologene: 80193
Tcam1
Name: testicular cell adhesion molecule 1
Synonyms: 4930570F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 75870
Homologene: 123944
Ccr9
Name: chemokine (C-C motif) receptor 9
Synonyms: GPR-9-6, Cmkbr10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12769
HGNC: HGNC:1610
Homologene: 22546
Ralb
Name: v-ral simian leukemia viral oncogene B
Synonyms: 5730472O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 64143
HGNC: HGNC:9840
Homologene: 20632
Olfr1113
Name: olfactory receptor 1113
Synonyms: GA_x6K02T2Q125-48697747-48698727, MOR264-25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 404327
Homologene: 27114
Kcna3
Name: potassium voltage-gated channel, shaker-related subfamily, member 3
Synonyms: Kv1.3, Mk-3, Kca1-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 16491
HGNC: HGNC:6221
Homologene: 128570
Papolb
Name: poly (A) polymerase beta (testis specific)
Synonyms: TPAP, Papt, Plap-ps, Papola-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56522
Homologene: 121622
Akr1b7
Name: aldo-keto reductase family 1, member B7
Synonyms: MVDP, Avdp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 11997
Homologene: 122176
Vmn1r74
Name: vomeronasal 1 receptor 74
Synonyms: V1rg5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 171240
Homologene: 110796
Cyp2a4
Name: cytochrome P450, family 2, subfamily a, polypeptide 4
Synonyms: Cyp15a1, D7Ucla4, testosterone 15alpha-hydroxylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13086
Homologene: 85917
Mlip
Name: muscular LMNA-interacting protein
Synonyms: 2310046A06Rik, CIP, cardiac ISL1-interacting protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 69642
Homologene: 90445
Irak1bp1
Name: interleukin-1 receptor-associated kinase 1 binding protein 1
Synonyms: SIMPL, AIP70, 4921528N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 65099
Homologene: 11300
Gm1553
Name: predicted gene 1553
Synonyms: LOC380643, Lcrn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 432480
VEGA: 10
Rxylt1
Name: ribitol xylosyltransferase 1
Synonyms: 6330415D21Rik, Tmem5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216395
Homologene: 8600
Cnpy2
Name: canopy FGF signaling regulator 2
Synonyms: Zsig9, 5330432A10Rik, D10Bwg1546e, Tmem4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 56530
VEGA: 10
Homologene: 40934
Pctp
Name: phosphatidylcholine transfer protein
Synonyms: PC-TP, StarD2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18559
HGNC: HGNC:8752
Homologene: 32054
Krt31
Name: keratin 31
Synonyms: Ha1, Kha1, MKHA-1, Krt1-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16660
HGNC: HGNC:6448
Homologene: 74433
Krt36
Name: keratin 36
Synonyms: HRa-1, Krt1-22, keratin 5, Krt1-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16673
HGNC: HGNC:6454
Homologene: 88459
Zfp184
Name: zinc finger protein 184 (Kruppel-like)
Synonyms: 4930500C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 193452
Homologene: 113602
Il10rb
Name: interleukin 10 receptor, beta
Synonyms: CRF2-4, D21S58h, Crfb4, D16H21S58, Il10r2, 6620401D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 16155
HGNC: HGNC:5965
Homologene: 523
Dcpp3
Name: demilune cell and parotid protein 3
Synonyms: EG620253
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 620253
VEGA: 17
Homologene: 103921
Olfr138
Name: olfactory receptor 138
Synonyms: Olfr89, MOR256-40P, GA_x6K02T2PSCP-2718585-2719523
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 170648
Homologene: 119758
Nanos1
Name: nanos C2HC-type zinc finger 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 332397
VEGA: 19
Homologene: 131234
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to C, chromosome 1 at 75,423,924 bp
  • G to C, chromosome 1 at 119,478,126 bp
  • C to T, chromosome 1 at 136,482,418 bp
  • A to T, chromosome 2 at 87,213,693 bp
  • T to C, chromosome 2 at 87,943,565 bp
  • T to A, chromosome 2 at 118,112,991 bp
  • T to A, chromosome 2 at 120,012,903 bp
  • T to A, chromosome 2 at 120,906,946 bp
  • T to A, chromosome 2 at 163,061,608 bp
  • T to C, chromosome 3 at 107,036,999 bp
  • A to C, chromosome 4 at 137,018,531 bp
  • A to G, chromosome 4 at 139,410,860 bp
  • A to T, chromosome 4 at 147,918,841 bp
  • T to C, chromosome 5 at 109,156,529 bp
  • A to G, chromosome 5 at 142,529,456 bp
  • T to G, chromosome 6 at 34,415,400 bp
  • T to C, chromosome 6 at 121,849,850 bp
  • C to T, chromosome 6 at 142,645,878 bp
  • T to C, chromosome 7 at 11,847,315 bp
  • T to A, chromosome 7 at 25,914,934 bp
  • A to T, chromosome 7 at 26,312,868 bp
  • T to C, chromosome 7 at 120,189,749 bp
  • G to T, chromosome 8 at 11,635,482 bp
  • T to A, chromosome 8 at 63,924,877 bp
  • T to A, chromosome 8 at 93,192,772 bp
  • A to T, chromosome 9 at 77,239,577 bp
  • T to A, chromosome 9 at 82,846,561 bp
  • A to T, chromosome 9 at 123,779,970 bp
  • T to C, chromosome 10 at 75,859,804 bp
  • T to C, chromosome 10 at 82,492,176 bp
  • T to C, chromosome 10 at 122,095,936 bp
  • T to A, chromosome 10 at 128,326,207 bp
  • C to T, chromosome 11 at 67,306,017 bp
  • A to G, chromosome 11 at 89,986,119 bp
  • A to G, chromosome 11 at 100,050,253 bp
  • C to T, chromosome 11 at 100,104,114 bp
  • T to A, chromosome 11 at 106,284,214 bp
  • A to G, chromosome 12 at 54,918,436 bp
  • G to T, chromosome 12 at 85,267,587 bp
  • C to A, chromosome 12 at 111,835,688 bp
  • C to T, chromosome 13 at 13,647,079 bp
  • T to A, chromosome 13 at 21,947,082 bp
  • C to T, chromosome 13 at 49,379,870 bp
  • T to C, chromosome 13 at 57,440,536 bp
  • A to T, chromosome 13 at 102,705,900 bp
  • A to G, chromosome 14 at 101,900,456 bp
  • C to T, chromosome 15 at 81,668,741 bp
  • T to C, chromosome 15 at 85,227,076 bp
  • T to A, chromosome 15 at 100,774,638 bp
  • A to G, chromosome 16 at 29,266,929 bp
  • G to A, chromosome 16 at 91,412,010 bp
  • A to T, chromosome 17 at 18,105,450 bp
  • A to T, chromosome 17 at 23,917,951 bp
  • T to A, chromosome 17 at 30,708,390 bp
  • G to T, chromosome 17 at 38,274,883 bp
  • G to A, chromosome 19 at 18,778,644 bp
  • A to G, chromosome 19 at 41,088,826 bp
  • A to G, chromosome 19 at 60,756,930 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0393 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038599-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.