Strain Name:
C57BL/6J-MtgxR0546Btlr/Mmmh
Stock Number:
038738-MU
Citation ID:
RRID:MMRRC_038738-MU
Other Names:
R0546 (G1), C57BL/6J-MtgxR0546Btlr
Major Collection:

Gene Information

Pkd1
Name: polycystin 1, transient receptor poteintial channel interacting
Synonyms: PC1, PC-1, polycystin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 18763
VEGA: 17
HGNC: HGNC:9008
Homologene: 250
Shprh
Name: SNF2 histone linker PHD RING helicase
Synonyms: D230017O13Rik, 2610103K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 268281
Homologene: 6489
Cyfip1
Name: cytoplasmic FMR1 interacting protein 1
Synonyms: l7Rl1, Sra-1, P140SRA-1, pl-1, Shyc, l(7)1Rl, E030028J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20430
Homologene: 22628
Sec23a
Name: SEC23 homolog A, COPII coat complex component
Synonyms: Sec23r, Msec23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 20334
Homologene: 4642
Zfhx3
Name: zinc finger homeobox 3
Synonyms: WBP9, Sci, A230102L03Rik, Atbf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 11906
HGNC: HGNC:777
Homologene: 21366
Xpo4
Name: exportin 4
Synonyms: B430309A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 57258
Homologene: 10733
Gpatch2l
Name: G patch domain containing 2 like
Synonyms: 1700020O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 70373
VEGA: 12
Homologene: 9942
Top2a
Name: topoisomerase (DNA) II alpha
Synonyms: Top-2, DNA Topoisomerase II alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 21973
Homologene: 830
Lgr4
Name: leucine-rich repeat-containing G protein-coupled receptor 4
Synonyms: A930009A08Rik, A330106J01Rik, Gpr48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 107515
Homologene: 10226
Ccdc18
Name: coiled-coil domain containing 18
Synonyms: 4932411G06Rik, 1700021E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 73254
Homologene: 35455
Actn1
Name: actinin, alpha 1
Synonyms: 3110023F10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 109711
VEGA: 12
HGNC: HGNC:163
Homologene: 55553
Dhfr
Name: dihydrofolate reductase
Synonyms: 8430436I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 13361
VEGA: 13
HGNC: HGNC:2861
Homologene: 56470
Ifitm2
Name: interferon induced transmembrane protein 2
Synonyms: mil-3, fragilis3, Ifitm3l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 80876
HGNC: HGNC:5413
Homologene: 74574
Ing1
Name: inhibitor of growth family, member 1
Synonyms: mING1h, 2610028J21Rik, p33Ing1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 26356
HGNC: HGNC:6062
Homologene: 40119
Crebbp
Name: CREB binding protein
Synonyms: KAT3A, CBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 12914
HGNC: HGNC:2348
Homologene: 68393
Zfp868
Name: zinc finger protein 868
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234362
HGNC: null
Homologene: 74376
Cnp
Name: 2',3'-cyclic nucleotide 3' phosphodiesterase
Synonyms: Cnp-1, CNPase, Cnp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 12799
HGNC: HGNC:2158
Homologene: 7672
Prune2
Name: prune homolog 2
Synonyms: 6330414G02Rik, A230083H22Rik, A330102H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 353211
VEGA: 19
Homologene: 18939
Agr3
Name: anterior gradient 3
Synonyms: E030025L21Rik, LOC380754
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 403205
Homologene: 45551
Cpa4
Name: carboxypeptidase A4
Synonyms: 1110019K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 71791
Homologene: 56753
Hspg2
Name: perlecan (heparan sulfate proteoglycan 2)
Synonyms: Pcn, Plc, perlecan, per
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 15530
HGNC: HGNC:5273
Homologene: 68473
Ap2a1
Name: adaptor-related protein complex 2, alpha 1 subunit
Synonyms: Adtaa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11771
HGNC: HGNC:561
Homologene: 68997
Plod2
Name: procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
Synonyms: Plod-2, lysyl hydroxylase 2, LH2, D530025C14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 26432
HGNC: HGNC:9082
Homologene: 22681
Sec31a
Name: Sec31 homolog A (S. cerevisiae)
Synonyms: 1810024J13Rik, Sec31l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 69162
Homologene: 42056
Uggt1
Name: UDP-glucose glycoprotein glucosyltransferase 1
Synonyms: 0910001L17Rik, A930007H10Rik, C820010P03Rik, Ugcgl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 320011
Homologene: 10586
Ift172
Name: intraflagellar transport 172
Synonyms: avc1, wim, 4930553F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 67661
Homologene: 15202
Dnajc6
Name: DnaJ heat shock protein family (Hsp40) member C6
Synonyms: 2810027M23Rik, auxilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 72685
Homologene: 8865
Myo15
Name: myosin XV
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17910
HGNC: HGNC:7594
Homologene: 56504
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Myh11
Name: myosin, heavy polypeptide 11, smooth muscle
Synonyms: smMHC, SM2, SM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 17880
VEGA: 16
HGNC: HGNC:7569
Homologene: 128512
Fer1l6
Name: fer-1-like 6 (C. elegans)
Synonyms: EG631797
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 631797
Homologene: 53396
Galnt18
Name: polypeptide N-acetylgalactosaminyltransferase 18
Synonyms: 2900011G21Rik, Galntl4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233733
Homologene: 18347
Zfp804a
Name: zinc finger protein 804A
Synonyms: C630007C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241514
Homologene: 18461
Slc16a7
Name: solute carrier family 16 (monocarboxylic acid transporters), member 7
Synonyms: 9030411M13Rik, MCT2, D630004K10Rik, 4921534N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 20503
Homologene: 20990
Snx25
Name: sorting nexin 25
Synonyms: LOC382008, SBBI31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 102141
Homologene: 23744
Ccdc180
Name: coiled-coil domain containing 180
Synonyms: LOC381522, E230008N13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 381522
Homologene: 117988
Stab1
Name: stabilin 1
Synonyms: MS-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 192187
Homologene: 9035
Dennd5a
Name: DENN/MADD domain containing 5A
Synonyms: ORF37, Rab6ip1, 1500012B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 19347
Homologene: 14584
Itgal
Name: integrin alpha L
Synonyms: Cd11a, LFA-1, Ly-21, Ly-15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 16408
HGNC: HGNC:6148
Homologene: 1666
Adam39
Name: a disintegrin and metallopeptidase domain 39
Synonyms: 1700056P18Rik, testase 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 546055
HGNC: HGNC:199
Homologene: 128364
Paox
Name: polyamine oxidase (exo-N4-amino)
Synonyms: Pao, 2410012F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 212503
Homologene: 72096
Alpk2
Name: alpha-kinase 2
Synonyms: Hak
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225638
Homologene: 50475
Trpv3
Name: transient receptor potential cation channel, subfamily V, member 3
Synonyms: VRL3, Nh, 1110036I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 246788
Homologene: 17040
Trim7
Name: tripartite motif-containing 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 94089
Homologene: 14113
Olfr1085
Name: olfactory receptor 1085
Synonyms: MOR191-1, GA_x6K02T2Q125-48147264-48146323
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258583
HGNC: null
Homologene: null
Mylk
Name: myosin, light polypeptide kinase
Synonyms: MLCK108, A930019C19Rik, Mlck, nmMlck, telokin, MLCK210, 9530072E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 107589
HGNC: HGNC:7590
Homologene: 14202
Aox4
Name: aldehyde oxidase 4
Synonyms: 2310003G12Rik, AOH2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 71872
HGNC: null
Homologene: 70273
Tmprss9
Name: transmembrane protease, serine 9
Synonyms: Serase-1B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 432478
VEGA: 10
Homologene: 115302
Gbp4
Name: guanylate binding protein 4
Synonyms: Mag-2, Mpa2, Mpa-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 17472
Homologene: 128731
Aass
Name: aminoadipate-semialdehyde synthase
Synonyms: LOR/SDH, Lorsdh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 30956
Homologene: 4212
Ube2ql1
Name: ubiquitin-conjugating enzyme E2Q family-like 1
Synonyms: 3110006E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 76980
VEGA: 13
Homologene: 15975
Itgav
Name: integrin alpha V
Synonyms: D430040G12Rik, 1110004F14Rik, 2610028E01Rik, vitronectin receptor alpha polypeptide (VNRA), alphav-integrin, CD51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16410
HGNC: HGNC:6150
Homologene: 20510
Hip1r
Name: huntingtin interacting protein 1 related
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 29816
Homologene: 78348
Smg8
Name: smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans)
Synonyms: 1200011M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 74133
Homologene: 32393
Olfr814
Name: olfactory receptor 814
Synonyms: MOR113-8, MOR113-5, GA_x6K02T2PULF-11553313-11552381
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 259165
Homologene: 133585
Fam110a
Name: family with sequence similarity 110, member A
Synonyms: 1700008J10Rik, 5430432M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 73847
Homologene: 12862
Steap4
Name: STEAP family member 4
Synonyms: Tiarp, Tnfaip9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 117167
Homologene: 36422
Fars2
Name: phenylalanine-tRNA synthetase 2 (mitochondrial)
Synonyms: 6720478K01Rik, 2810431B21Rik, Fars1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 69955
VEGA: 13
Homologene: 4788
Sbds
Name: SBDS ribosome maturation factor
Synonyms: 4733401P19Rik, Shwachman-Bodian-Diamond syndrome homolog (human)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 66711
Homologene: 6438
Olfr128
Name: olfactory receptor 128
Synonyms: MOR218-13, GA_x6K02T2PSCP-2374126-2375048
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 383243
HGNC: null
Homologene: 134080
Olfr1084
Name: olfactory receptor 1084
Synonyms: MOR192-3, GA_x6K02T2Q125-48121788-48120847, MOR192-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258235
HGNC: null
Homologene: 104285
Mrgprb3
Name: MAS-related GPR, member B3
Synonyms: MrgB3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 404238
HGNC: null
Homologene: 138632
Car5b
Name: carbonic anhydrase 5b, mitochondrial
Synonyms: CAVB, 7330410H16Rik, D730005F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 56078
HGNC: HGNC:1378
Homologene: 21413
Olfr1158
Name: olfactory receptor 1158
Synonyms: MOR173-3, GA_x6K02T2Q125-49480812-49481753
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258639
HGNC: null
Homologene: null
Jazf1
Name: JAZF zinc finger 1
Synonyms: Jaz1, Tip27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 231986
Homologene: 18291
Olfr608
Name: olfactory receptor 608
Synonyms: MOR26-3, GA_x6K02T2PBJ9-6191595-6192545
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258751
HGNC: null
Homologene: null
Mgat4d
Name: MGAT4 family, member C
Synonyms: 4933434I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 67555
Homologene: 128538
Ctrl
Name: chymotrypsin-like
Synonyms: Ctra-1, chymopasin, 1810004D15Rik, 0910001G08Rik, Ctra1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 109660
HGNC: HGNC:2524
Homologene: 37549
St3gal2
Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 2
Synonyms: ST3GalII, Siat5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 20444
Homologene: 5047
Trhr2
Name: thyrotropin releasing hormone receptor 2
Synonyms: TRH-R2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 170732
HGNC: null
Homologene: 44052
Snx22
Name: sorting nexin 22
Synonyms: LOC382083
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 382083
VEGA: 9
Homologene: 11723
Gabra1
Name: gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
Synonyms: GABAAR alpha1, GABAA alpha 1, Gabra-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14394
HGNC: HGNC:4075
Homologene: 629
Zfp354c
Name: zinc finger protein 354C
Synonyms: Kid3, AJ18, 5330421P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 30944
Homologene: 56606
Amz2
Name: archaelysin family metallopeptidase 2
Synonyms: ESTM12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 100503496
Homologene: null
Stfa3
Name: stefin A3
Synonyms: Stf3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 20863
VEGA: 16
HGNC: HGNC:2481
Homologene: 115602
Ccdc112
Name: coiled-coil domain containing 112
Synonyms: 8430438M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 240261
VEGA: 18
Homologene: 17617
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 36,195,971 bp
  • A to G, chromosome 1 at 58,250,174 bp
  • A to G, chromosome 2 at 76,745,519 bp
  • A to G, chromosome 2 at 82,258,920 bp
  • G to T, chromosome 2 at 83,803,242 bp
  • T to A, chromosome 2 at 86,639,229 bp
  • C to T, chromosome 2 at 86,657,891 bp
  • T to A, chromosome 2 at 87,990,472 bp
  • T to A, chromosome 2 at 109,999,421 bp
  • T to C, chromosome 2 at 151,970,812 bp
  • A to T, chromosome 4 at 45,904,597 bp
  • A to T, chromosome 4 at 101,635,191 bp
  • A to G, chromosome 4 at 137,502,294 bp
  • T to C, chromosome 5 at 7,975,870 bp
  • T to C, chromosome 5 at 31,257,601 bp
  • T to C, chromosome 5 at 100,404,070 bp
  • T to C, chromosome 5 at 105,120,970 bp
  • A to T, chromosome 5 at 108,174,964 bp
  • T to C, chromosome 5 at 123,999,051 bp
  • G to T, chromosome 5 at 130,254,078 bp
  • A to G, chromosome 6 at 23,077,077 bp
  • T to C, chromosome 6 at 30,580,963 bp
  • A to G, chromosome 6 at 52,777,696 bp
  • C to T, chromosome 7 at 44,904,708 bp
  • T to C, chromosome 7 at 48,643,515 bp
  • C to T, chromosome 7 at 55,922,816 bp
  • A to G, chromosome 7 at 103,470,700 bp
  • A to G, chromosome 7 at 109,921,426 bp
  • T to G, chromosome 7 at 111,508,141 bp
  • C to T, chromosome 7 at 127,310,314 bp
  • G to T, chromosome 7 at 140,131,678 bp
  • A to G, chromosome 7 at 140,955,743 bp
  • A to G, chromosome 8 at 11,557,031 bp
  • G to A, chromosome 8 at 40,826,431 bp
  • A to G, chromosome 8 at 46,103,630 bp
  • A to G, chromosome 8 at 69,612,231 bp
  • A to G, chromosome 8 at 83,355,721 bp
  • A to G, chromosome 8 at 105,932,334 bp
  • A to G, chromosome 8 at 108,794,187 bp
  • A to G, chromosome 8 at 110,970,106 bp
  • A to G, chromosome 8 at 122,358,489 bp
  • T to A, chromosome 9 at 66,068,777 bp
  • T to A, chromosome 9 at 92,595,335 bp
  • T to A, chromosome 10 at 11,183,887 bp
  • C to A, chromosome 10 at 80,899,323 bp
  • A to G, chromosome 10 at 125,230,873 bp
  • G to A, chromosome 10 at 129,874,538 bp
  • T to A, chromosome 11 at 42,162,601 bp
  • A to G, chromosome 11 at 48,845,509 bp
  • A to T, chromosome 11 at 50,815,630 bp
  • A to G, chromosome 11 at 60,506,313 bp
  • A to T, chromosome 11 at 73,297,187 bp
  • T to C, chromosome 11 at 87,083,613 bp
  • A to G, chromosome 11 at 98,999,226 bp
  • A to G, chromosome 11 at 100,580,723 bp
  • T to A, chromosome 11 at 109,433,954 bp
  • C to A, chromosome 12 at 35,928,330 bp
  • T to C, chromosome 12 at 58,985,167 bp
  • C to T, chromosome 12 at 80,178,434 bp
  • A to G, chromosome 12 at 86,288,848 bp
  • G to T, chromosome 13 at 36,204,586 bp
  • T to C, chromosome 13 at 69,739,300 bp
  • G to A, chromosome 13 at 92,368,184 bp
  • C to T, chromosome 14 at 31,139,550 bp
  • A to G, chromosome 14 at 57,613,274 bp
  • A to T, chromosome 15 at 58,558,408 bp
  • A to T, chromosome 16 at 4,085,807 bp
  • A to C, chromosome 16 at 14,205,628 bp
  • G to C, chromosome 16 at 34,879,475 bp
  • T to A, chromosome 16 at 36,452,257 bp
  • T to C, chromosome 17 at 24,580,138 bp
  • T to A, chromosome 17 at 37,924,338 bp
  • A to G, chromosome 18 at 46,291,072 bp
  • T to C, chromosome 18 at 65,306,717 bp
  • T to C, chromosome 19 at 17,020,666 bp
  • G to A, chromosome X at 163,979,301 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0546 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038738-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.