Strain Name:
C57BL/6J-MtgxR0556Btlr/Mmmh
Stock Number:
038748-MU
Citation ID:
RRID:MMRRC_038748-MU
Other Names:
R0556 (G1), C57BL/6J-MtgxR0556Btlr
Major Collection:

Gene Information

Colgalt2
Name: collagen beta(1-O)galactosyltransferase 2
Synonyms: Glt25d2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269132
Homologene: 22865
Septin3
Name: septin 3
Synonyms: Sep3, B530002E20Rik, 3110018K01Rik, Sept3, Gm46500
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 108168219
VEGA: 15
Homologene: 99740
Plcd3
Name: phospholipase C, delta 3
Synonyms: 2610205J15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 72469
HGNC: HGNC:9061
Homologene: 14858
Mtor
Name: mechanistic target of rapamycin kinase
Synonyms: FKBP-rapamycin-associated protein FRAP, 2610315D21Rik, RAPT1, RAFT1, flat, Frap1, mechanistic target of rapamycin (serine/threonine kinase)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56717
HGNC: HGNC:3942
Homologene: 3637
Synj2
Name: synaptojanin 2
Synonyms: SJ2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20975
Homologene: 117703
Ddx54
Name: DEAD box helicase 54
Synonyms: APR-5, DP97, 2410015A15Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71990
Homologene: 5590
Prr12
Name: proline rich 12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233210
Homologene: 18957
Trip11
Name: thyroid hormone receptor interactor 11
Synonyms: 3110031G15Rik, 2610511G22Rik, 6030460N08Rik, TRIP230, GMAP-210
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 109181
Homologene: 20897
Bms1
Name: BMS1, ribosome biogenesis factor
Synonyms: Bms1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 213895
Homologene: 7065
Clec16a
Name: C-type lectin domain family 16, member A
Synonyms: 4932416N17Rik, curt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 74374
Homologene: 71019
Bmpr2
Name: bone morphogenetic protein receptor, type II (serine/threonine kinase)
Synonyms: BMPR-II, BMP-2, 2610024H22Rik, BMPRII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12168
HGNC: HGNC:1078
Homologene: 929
Cntnap1
Name: contactin associated protein-like 1
Synonyms: p190, Caspr, Nrxn4, NCP1, paranodin, shm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 53321
HGNC: HGNC:8011
Homologene: 2693
Erap1
Name: endoplasmic reticulum aminopeptidase 1
Synonyms: PILSAP, ERAAP, Arts1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 80898
VEGA: 13
Homologene: 56754
Uchl1
Name: ubiquitin carboxy-terminal hydrolase L1
Synonyms: PGP9.5, PGP 9.5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22223
Homologene: 37894
Dock7
Name: dedicator of cytokinesis 7
Synonyms: 3110056M06Rik, LOC242555, m
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67299
Homologene: 23566
Ccn3
Name: cellular communication network factor 3
Synonyms: C130088N23Rik, CCN3, Nov
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 18133
HGNC: HGNC:7885
Homologene: 1884
Eif4g1
Name: eukaryotic translation initiation factor 4, gamma 1
Synonyms: E030015G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 208643
HGNC: HGNC:3296
Homologene: 110725
Morc2a
Name: microrchidia 2A
Synonyms: 8430403M08Rik, Zcwcc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74522
Homologene: 8966
Pnpla7
Name: patatin-like phospholipase domain containing 7
Synonyms: E430013P11Rik, NRE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241274
Homologene: 62431
Ppp1r12b
Name: protein phosphatase 1, regulatory subunit 12B
Synonyms: 1810037O03Rik, 9530009M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329251
HGNC: HGNC:7619
Homologene: 135710
Prickle1
Name: prickle planar cell polarity protein 1
Synonyms: 1110058P22Rik, mpk1, b2b019Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 106042
Homologene: 17686
Aldh1a1
Name: aldehyde dehydrogenase family 1, subfamily A1
Synonyms: ALDH1, E1, Ahd-2, Ahd2, Raldh1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 11668
HGNC: HGNC:402
Homologene: 110441
Col24a1
Name: collagen, type XXIV, alpha 1
Synonyms: 5430404K19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71355
Homologene: 65061
Tnik
Name: TRAF2 and NCK interacting kinase
Synonyms: 4831440I19Rik, 1500031A17Rik, C530008O15Rik, C630040K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 665113
Homologene: 77943
Vwa3b
Name: von Willebrand factor A domain containing 3B
Synonyms: 4921511C04Rik, A230074B11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70853
Homologene: 27053
Itga4
Name: integrin alpha 4
Synonyms: VLA-4 receptor, alpha 4 subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16401
HGNC: HGNC:6140
Homologene: 37364
Garre1
Name: granule associated Rac and RHOG effector 1
Synonyms: 4931406P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233103
Homologene: 8795
9530053A07Rik
Name: RIKEN cDNA 9530053A07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 319482
Homologene: 130055
Stard9
Name: START domain containing 9
Synonyms: N-3 kinesin, Kif16a, 4831403C07Rik, E230025N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 668880
Homologene: 130712
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22635
Homologene: 124417
Cct6b
Name: chaperonin containing Tcp1, subunit 6b (zeta)
Synonyms: CCTzeta-2, Cctz-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12467
HGNC: HGNC:1621
Homologene: 55978
Taar2
Name: trace amine-associated receptor 2
Synonyms: Gpr58
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 209512
HGNC: HGNC:4514
Homologene: 110760
Olfr743
Name: olfactory receptor 743
Synonyms: GA_x6K02T2N6FY-3870-3385, GA_x6K02T2N6FY-2320-2039, GA_x6K02T2PMLR-6243196-6244132, MOR106-8P, MOR106-14, Olfr265, Olfr743-ps1, Olfr264
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219019
Homologene: 74163
Cpd
Name: carboxypeptidase D
Synonyms: D830034L15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12874
HGNC: HGNC:2301
Homologene: 999
Ttll9
Name: tubulin tyrosine ligase-like family, member 9
Synonyms: 4930509O20Rik, 1700016F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74711
Homologene: 41769
Myo1h
Name: myosin 1H
Synonyms: 4631401O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231646
Homologene: 82639
Morc2b
Name: microrchidia 2B
Synonyms: 4932411A10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 240069
Homologene: 18615
Igsf10
Name: immunoglobulin superfamily, member 10
Synonyms: 6530405F15Rik, CMF608, Adlican2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242050
Homologene: 18712
Cd101
Name: CD101 antigen
Synonyms: LOC381460, Igsf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 630146
HGNC: HGNC:5949
Homologene: 3142
Rgl3
Name: ral guanine nucleotide dissociation stimulator-like 3
Synonyms: 1300003D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71746
VEGA: 9
Homologene: 11363
Sacs
Name: sacsin
Synonyms: E130115J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 50720
Acad11
Name: acyl-Coenzyme A dehydrogenase family, member 11
Synonyms: 5730439E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102632
Homologene: 49896
Lhcgr
Name: luteinizing hormone/choriogonadotropin receptor
Synonyms: Lhr, Gpcr19-rs1, LH-R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16867
VEGA: 17
HGNC: HGNC:6585
Homologene: 37276
4930402F06Rik
Name: RIKEN cDNA 4930402F06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74854
Homologene: 78017
Simc1
Name: SUMO-interacting motifs containing 1
Synonyms: 4732471D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 319719
Homologene: 131217
Olfr920
Name: olfactory receptor 920
Synonyms: GA_x6K02T2PVTD-32458442-32459374, MOR165-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258783
VEGA: 9
Ift22
Name: intraflagellar transport 22
Synonyms: 3110017O03Rik, Rabl5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 67286
Homologene: 11253
Ccno
Name: cyclin O
Synonyms: Ung2, Ccnu
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218630
VEGA: 13
Homologene: 50171
Ptk2b
Name: PTK2 protein tyrosine kinase 2 beta
Synonyms: CAKbeta, Raftk, calcium-dependent tyrosine kinase, related adhesion focal tyrosine kinase, cellular adhesion kinase beta, proline-rich tyrosine kinase 2, PYK2, E430023O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 19229
HGNC: HGNC:9612
Homologene: 23001
Prelid2
Name: PRELI domain containing 2
Synonyms: 1700003A01Rik, C330008K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 77619
VEGA: 18
Homologene: 45749
Zfp687
Name: zinc finger protein 687
Synonyms: 4931408L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 78266
Homologene: 10827
Olfr1196
Name: olfactory receptor 1196
Synonyms: GA_x6K02T2Q125-50181139-50180195, MOR225-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258456
Homologene: 123770
Cab39
Name: calcium binding protein 39
Synonyms: 39kDa, MO25alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12283
Homologene: 69212
Cyp3a16
Name: cytochrome P450, family 3, subfamily a, polypeptide 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13114
HGNC: HGNC:2638
Homologene: 133568
Mau2
Name: MAU2 sister chromatid cohesion factor
Synonyms: A930019L04Rik, 9130404D08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74549
Homologene: 12574
Tlr5
Name: toll-like receptor 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 53791
Homologene: 20698
Mstn
Name: myostatin
Synonyms: Gdf8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17700
HGNC: HGNC:4223
Homologene: 3850
Igkv4-71
Name: immunoglobulin kappa chain variable 4-71
Synonyms: Gm16730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 434586
Ltk
Name: leukocyte tyrosine kinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17005
HGNC: HGNC:6721
Homologene: 130502
Tmco2
Name: transmembrane and coiled-coil domains 2
Synonyms: 1700028F16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69469
Homologene: 77950
Fbxo6
Name: F-box protein 6
Synonyms: Fbx6b, FBG2, Fbs2, Fbxo6b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 50762
Homologene: 9274
Gnat3
Name: guanine nucleotide binding protein, alpha transducing 3
Synonyms: Ggust, Gtn, alpha-gustducin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 242851
Homologene: 24284
Ces1a
Name: carboxylesterase 1A
Synonyms: Gm4976
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244595
HGNC: HGNC:1863
Homologene: 134142
1600012H06Rik
Name: RIKEN cDNA 1600012H06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 67912
Homologene: 57051
AC148991.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 37,164,485 bp
  • A to T, chromosome 1 at 53,064,125 bp
  • C to T, chromosome 1 at 59,815,328 bp
  • A to G, chromosome 1 at 85,835,491 bp
  • T to A, chromosome 1 at 134,777,322 bp
  • C to T, chromosome 1 at 152,471,813 bp
  • A to G, chromosome 1 at 182,974,151 bp
  • T to A, chromosome 2 at 25,052,301 bp
  • T to C, chromosome 2 at 35,390,470 bp
  • T to C, chromosome 2 at 79,325,639 bp
  • A to C, chromosome 2 at 88,700,771 bp
  • G to A, chromosome 2 at 119,755,727 bp
  • T to C, chromosome 2 at 120,698,923 bp
  • T to C, chromosome 2 at 152,973,606 bp
  • A to T, chromosome 3 at 28,625,218 bp
  • A to G, chromosome 3 at 59,328,875 bp
  • G to T, chromosome 3 at 95,010,408 bp
  • A to C, chromosome 3 at 101,020,654 bp
  • A to G, chromosome 3 at 145,314,728 bp
  • A to T, chromosome 4 at 98,945,189 bp
  • A to G, chromosome 4 at 121,109,117 bp
  • G to T, chromosome 4 at 148,146,175 bp
  • A to G, chromosome 4 at 148,469,380 bp
  • T to G, chromosome 5 at 18,019,598 bp
  • A to G, chromosome 5 at 66,682,481 bp
  • A to G, chromosome 5 at 114,319,791 bp
  • T to A, chromosome 5 at 120,619,654 bp
  • T to A, chromosome 5 at 136,911,291 bp
  • T to C, chromosome 5 at 137,454,220 bp
  • C to A, chromosome 5 at 145,455,980 bp
  • A to G, chromosome 6 at 69,243,187 bp
  • A to G, chromosome 6 at 118,413,179 bp
  • C to T, chromosome 7 at 28,159,378 bp
  • T to C, chromosome 7 at 34,239,797 bp
  • A to G, chromosome 7 at 45,030,669 bp
  • G to C, chromosome 8 at 70,042,432 bp
  • T to C, chromosome 8 at 93,045,112 bp
  • T to A, chromosome 9 at 21,975,844 bp
  • A to T, chromosome 9 at 38,755,745 bp
  • A to G, chromosome 9 at 104,115,302 bp
  • A to G, chromosome 10 at 23,940,895 bp
  • T to C, chromosome 11 at 3,681,809 bp
  • A to G, chromosome 11 at 76,802,345 bp
  • A to G, chromosome 11 at 82,719,444 bp
  • T to C, chromosome 11 at 101,183,996 bp
  • G to A, chromosome 11 at 103,077,806 bp
  • C to A, chromosome 12 at 101,884,518 bp
  • T to C, chromosome 13 at 54,525,347 bp
  • T to A, chromosome 13 at 74,660,325 bp
  • T to C, chromosome 13 at 112,988,286 bp
  • T to C, chromosome 14 at 50,533,924 bp
  • A to G, chromosome 14 at 61,183,958 bp
  • A to G, chromosome 14 at 66,172,144 bp
  • A to T, chromosome 15 at 54,749,167 bp
  • G to T, chromosome 15 at 82,283,765 bp
  • A to G, chromosome 15 at 93,500,781 bp
  • A to G, chromosome 16 at 10,638,785 bp
  • A to T, chromosome 16 at 20,675,794 bp
  • T to A, chromosome 17 at 6,037,955 bp
  • T to A, chromosome 17 at 14,943,951 bp
  • A to T, chromosome 17 at 33,137,838 bp
  • A to T, chromosome 17 at 88,772,063 bp
  • T to A, chromosome 18 at 41,951,180 bp
  • C to A, chromosome 19 at 11,013,701 bp
  • A to T, chromosome 19 at 20,634,478 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0556 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038748-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.