Strain Name:
C57BL/6J-MtgxR0662Btlr/Mmmh
Stock Number:
038847-MU
Citation ID:
RRID:MMRRC_038847-MU
Other Names:
R0662 (G1), C57BL/6J-MtgxR0662Btlr
Major Collection:

Gene Information

Shprh
Name: SNF2 histone linker PHD RING helicase
Synonyms: D230017O13Rik, 2610103K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 268281
Homologene: 6489
Map4k5
Name: mitogen-activated protein kinase kinase kinase kinase 5
Synonyms: GCKR, KHS, MAPKKKK5, 4432415E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 399510
HGNC: HGNC:6867
Homologene: 38199
Pank3
Name: pantothenate kinase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 211347
Homologene: 56999
Eno2
Name: enolase 2, gamma neuronal
Synonyms: Eno-2, D6Ertd375e, NSE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 13807
HGNC: HGNC:3353
Homologene: 74414
Myo1e
Name: myosin IE
Synonyms: 2310020N23Rik, 9130023P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71602
VEGA: 9
HGNC: HGNC:7599
Homologene: 55864
Denn2b
Name: DENN domain containing 2B
Synonyms: St5, 2010004M01Rik, 2610305K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76954
Homologene: 3951
Carmil1
Name: capping protein regulator and myosin 1 linker 1
Synonyms: Lrrc16, 1110037D04Rik, Lrrc16a, Carmil
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 68732
Homologene: 9757
Kat6b
Name: K(lysine) acetyltransferase 6B
Synonyms: B130044K16Rik, querkopf, Myst4, monocytic leukemia, qkf, Morf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 54169
Homologene: 136480
Cul3
Name: cullin 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 26554
HGNC: HGNC:2553
Homologene: 2661
Chd9
Name: chromodomain helicase DNA binding protein 9
Synonyms: 9030205D12Rik, A330063D19Rik, 1810014J18Rik, AD013
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 109151
Homologene: 11844
Nr2c1
Name: nuclear receptor subfamily 2, group C, member 1
Synonyms: Eenr, TR2, 4831444H07Rik, Tr2-11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22025
HGNC: HGNC:7971
Homologene: 55731
Topbp1
Name: topoisomerase (DNA) II binding protein 1
Synonyms: 2810429C13Rik, 1110031N14Rik, D430026L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235559
Homologene: 38262
Fam120c
Name: family with sequence similarity 120, member C
Synonyms: orf34, D930001I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 207375
Homologene: 9876
Zfp719
Name: zinc finger protein 719
Synonyms: mszf6, 9430094P17Rik, C630016O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 210105
Cpsf7
Name: cleavage and polyadenylation specific factor 7
Synonyms: 5730453I16Rik, C330017N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 269061
VEGA: 19
Homologene: 11731
Unc5b
Name: unc-5 netrin receptor B
Synonyms: D10Bwg0792e, Unc5h2, 6330415E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 107449
VEGA: 10
Homologene: 32538
Cacng3
Name: calcium channel, voltage-dependent, gamma subunit 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 54376
HGNC: HGNC:1407
Homologene: 4767
Ubxn1
Name: UBX domain protein 1
Synonyms: 4930455J02Rik, T25529, D19Ertd721e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225896
VEGA: 19
Homologene: 9283
Clec12b
Name: C-type lectin domain family 12, member B
Synonyms: 4933425B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 71183
Homologene: 19247
Mmp27
Name: matrix metallopeptidase 27
Synonyms: LOC234911
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 234911
Homologene: 23345
Cand2
Name: cullin-associated and neddylation-dissociated 2 (putative)
Synonyms: Tp120b, 2210404G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67088
Homologene: 41657
Tecpr2
Name: tectonin beta-propeller repeat containing 2
Synonyms: 4930573I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 104859
VEGA: 12
Homologene: 8897
Frmd6
Name: FERM domain containing 6
Synonyms: 4930488L10Rik, 2610019M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319710
VEGA: 12
Homologene: 12449
Zfp975
Name: zinc finger protein 975
Synonyms: Gm5595
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 434179
Homologene: 134004
Sez6l
Name: seizure related 6 homolog like
Synonyms: Acig1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56747
Homologene: 10895
Ryr1
Name: ryanodine receptor 1, skeletal muscle
Synonyms: Ryr, skrr, calcium release channel isoform 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20190
Homologene: 68069
Hormad1
Name: HORMA domain containing 1
Synonyms: 4921522K05Rik, Nohma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67981
Homologene: 69415
Myo6
Name: myosin VI
Synonyms: Myo6rsv, rsv, Tlc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17920
HGNC: HGNC:7605
Homologene: 56417
Ush2a
Name: usherin
Synonyms: MUSH2A, LOC381317, Ushrn, A930011D15Rik, LOC269160, A930037M10Rik, Ush2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22283
Homologene: 66151
Celsr2
Name: cadherin, EGF LAG seven-pass G-type receptor 2
Synonyms: flamingo, Adgrc2, mfmi1, EGFL2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 53883
HGNC: HGNC:3231
Homologene: 1078
Olfr457
Name: olfactory receptor 457
Synonyms: MOR257-1, GA_x6K02T2P3E9-5088893-5089834
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 258989
Homologene: 133701
Ptchd4
Name: patched domain containing 4
Synonyms: 3110082D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 627626
VEGA: 17
Homologene: 78322
Slc3a1
Name: solute carrier family 3, member 1
Synonyms: D2H, NTAA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20532
VEGA: 17
Homologene: 37289
Olfr703
Name: olfactory receptor 703
Synonyms: MOR283-7, GA_x6K02T2PBJ9-9222217-9223176
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258589
Dcaf11
Name: DDB1 and CUL4 associated factor 11
Synonyms: Wdr23, D14Ucla1, 0710008A13Rik, GLO14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 28199
Homologene: 11886
C4b
Name: complement component 4B (Chido blood group)
Synonyms: C4, Ss
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12268
Homologene: 36030
Chil1
Name: chitinase-like 1
Synonyms: Brp39, Gp39, Chi3l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12654
HGNC: HGNC:1932
Homologene: 55569
Fyb2
Name: FYN binding protein 2
Synonyms: 1700024P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242594
Homologene: 52981
Plekhh1
Name: pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
Synonyms: D630024D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 211945
VEGA: 12
Homologene: 121939
AC138665.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Itih1
Name: inter-alpha trypsin inhibitor, heavy chain 1
Synonyms: inter-alpha (globulin) inhibitor, H1 polypeptide, Itih-1, Intin1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16424
HGNC: HGNC:6166
Homologene: 1667
Mug2
Name: murinoglobulin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17837
Homologene: 136663
Kcna2
Name: potassium voltage-gated channel, shaker-related subfamily, member 2
Synonyms: Mk-2, Kv1.2, Akr6a4, Kca1-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 16490
HGNC: HGNC:6220
Homologene: 21034
Olfr862
Name: olfactory receptor 862
Synonyms: GA_x6K02T2PVTD-13624132-13623212, MOR146-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258555
Homologene: 115540
Itgbl1
Name: integrin, beta-like 1
Synonyms: B930011D01Rik, with EGF-like repeat domains
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 223272
HGNC: HGNC:6164
Homologene: 3519
Gm9912
Name: predicted gene 9912
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Slc5a5
Name: solute carrier family 5 (sodium iodide symporter), member 5
Synonyms: NIS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 114479
Homologene: 37311
Olfr292
Name: olfactory receptor 292
Synonyms: GA_x6K02T2NHDJ-9425121-9424195, MOR220-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258613
Homologene: 115526
A1cf
Name: APOBEC1 complementation factor
Synonyms: ACF, apobec-1 complementation factor, 1810073H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 69865
VEGA: 19
Homologene: 16363
Ankrd53
Name: ankyrin repeat domain 53
Synonyms: 4930564N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 75305
Homologene: 49810
Syne3
Name: spectrin repeat containing, nuclear envelope family member 3
Synonyms: nesprin-3, nesprin-3alpha, nesprin-3beta, 4831426I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 212073
VEGA: 12
Homologene: 17625
Vmn2r76
Name: vomeronasal 2, receptor 76
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 675969
Homologene: 104330
Zbtb24
Name: zinc finger and BTB domain containing 24
Synonyms: ZNF450
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 268294
VEGA: 10
Homologene: 8870
Olfr911-ps1
Name: olfactory receptor 911, pseudogene 1
Synonyms: GA_x6K02T2PVTD-32223906-32224841, MOR165-1, GA_x6K02T2PVTD-32247224-32248163, MOR166-1, Olfr909
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258873
VEGA: 9
Homologene: 74148
Rhcg
Name: Rhesus blood group-associated C glycoprotein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56315
Homologene: 32310
Armcx2
Name: armadillo repeat containing, X-linked 2
Synonyms: 3230401N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 67416
Homologene: 12125
Utp14b
Name: UTP14B small subunit processome component
Synonyms: jsd, 4932411L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 195434
Homologene: 78703
Xrcc2
Name: X-ray repair complementing defective repair in Chinese hamster cells 2
Synonyms: 8030409M04Rik, 4921524O04Rik, RecA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 57434
Homologene: 3964
Zdhhc2
Name: zinc finger, DHHC domain containing 2
Synonyms: 5730415P04Rik, 6430583A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 70546
Homologene: 81667
Olfr77
Name: olfactory receptor 77
Synonyms: MOR143-1, 18A, GA_x6K02T2PVTD-13660026-13660964
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258336
Homologene: 133688
Itga7
Name: integrin alpha 7
Synonyms: [a]7, alpha7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16404
VEGA: 10
HGNC: HGNC:6143
Homologene: 37592
Npb
Name: neuropeptide B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 208990
Homologene: 102151
Vmn1r219
Name: vomeronasal 1 receptor 219
Synonyms: V1rh13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 171272
Homologene: 110880
Olfr131
Name: olfactory receptor 131
Synonyms: MOR256-4, GA_x6K02T2PSCP-2531299-2530355
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258867
Homologene: 105889
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 78,664,999 bp
  • T to C, chromosome 1 at 80,271,565 bp
  • A to C, chromosome 1 at 134,188,573 bp
  • A to G, chromosome 1 at 188,351,093 bp
  • A to T, chromosome 3 at 59,606,743 bp
  • T to C, chromosome 3 at 95,575,599 bp
  • A to T, chromosome 3 at 107,105,401 bp
  • A to T, chromosome 3 at 108,398,520 bp
  • C to T, chromosome 3 at 149,185,387 bp
  • G to A, chromosome 4 at 104,995,698 bp
  • A to G, chromosome 5 at 25,698,343 bp
  • A to T, chromosome 5 at 112,473,422 bp
  • C to T, chromosome 6 at 42,471,774 bp
  • G to T, chromosome 6 at 83,763,643 bp
  • A to G, chromosome 6 at 115,787,210 bp
  • T to A, chromosome 6 at 122,036,235 bp
  • A to T, chromosome 6 at 124,763,811 bp
  • A to C, chromosome 6 at 129,376,237 bp
  • A to T, chromosome 7 at 29,100,189 bp
  • T to C, chromosome 7 at 42,662,526 bp
  • G to A, chromosome 7 at 43,584,254 bp
  • C to T, chromosome 7 at 79,599,729 bp
  • C to T, chromosome 7 at 86,230,370 bp
  • A to G, chromosome 7 at 86,694,630 bp
  • A to T, chromosome 7 at 106,844,649 bp
  • G to T, chromosome 7 at 109,557,426 bp
  • T to C, chromosome 7 at 122,768,359 bp
  • T to C, chromosome 8 at 40,447,098 bp
  • T to A, chromosome 8 at 70,883,875 bp
  • A to C, chromosome 8 at 90,977,676 bp
  • T to A, chromosome 9 at 7,577,650 bp
  • T to C, chromosome 9 at 19,883,952 bp
  • G to C, chromosome 9 at 19,920,500 bp
  • T to A, chromosome 9 at 38,524,026 bp
  • T to C, chromosome 9 at 70,341,268 bp
  • A to G, chromosome 9 at 80,245,746 bp
  • T to C, chromosome 9 at 103,320,339 bp
  • G to A, chromosome 10 at 11,186,847 bp
  • G to A, chromosome 10 at 41,462,279 bp
  • C to A, chromosome 10 at 60,772,583 bp
  • A to T, chromosome 10 at 94,190,738 bp
  • G to T, chromosome 10 at 128,953,531 bp
  • T to C, chromosome 11 at 35,778,650 bp
  • A to T, chromosome 11 at 120,608,752 bp
  • A to G, chromosome 12 at 69,813,153 bp
  • A to T, chromosome 12 at 70,899,444 bp
  • A to G, chromosome 12 at 79,078,993 bp
  • T to G, chromosome 12 at 104,961,510 bp
  • A to G, chromosome 12 at 110,896,228 bp
  • T to C, chromosome 13 at 23,163,453 bp
  • A to T, chromosome 13 at 24,121,828 bp
  • AGAGGAGGAGGAGGAGGAGGA to AGAGGAGGAGGAGGAGGA, chromosome 14 at 21,662,349 bp
  • T to C, chromosome 14 at 30,933,360 bp
  • T to C, chromosome 14 at 55,565,507 bp
  • T to A, chromosome 14 at 123,827,894 bp
  • G to A, chromosome 17 at 34,730,888 bp
  • A to G, chromosome 17 at 38,082,933 bp
  • A to G, chromosome 17 at 42,502,576 bp
  • A to G, chromosome 17 at 85,037,207 bp
  • T to A, chromosome 19 at 8,875,197 bp
  • T to C, chromosome 19 at 10,526,008 bp
  • T to C, chromosome 19 at 31,920,938 bp
  • G to A, chromosome X at 134,805,636 bp
  • T to G, chromosome X at 151,465,494 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0662 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038847-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.