Strain Name:
C57BL/6J-MtgxR0677Btlr/Mmmh
Stock Number:
038862-MU
Citation ID:
RRID:MMRRC_038862-MU
Other Names:
R0677 (G1), C57BL/6J-MtgxR0677Btlr
Major Collection:

Gene Information

Uri1
Name: URI1, prefoldin-like chaperone
Synonyms: Rmp, C80913, NNX3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 19777
Homologene: 2813
BC004004
Name: cDNA sequence BC004004
Synonyms: 2400006G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 80748
Homologene: 12728
Washc2
Name: WASH complex subunit 2`
Synonyms: Fam21, D6Wsu116e, C530005J20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 28006
Homologene: 41686
Depdc5
Name: DEP domain containing 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 277854
Homologene: 34718
Prom1
Name: prominin 1
Synonyms: 4932416E19Rik, AC133, Prom-1, CD133, Prom
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19126
HGNC: HGNC:9454
Homologene: 4390
Wipi2
Name: WD repeat domain, phosphoinositide interacting 2
Synonyms: 2510001I10Rik, 1110018O08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74781
Homologene: 90887
Gp5
Name: glycoprotein 5 (platelet)
Synonyms: GPV, GP V
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 14729
VEGA: 16
HGNC: HGNC:4443
Homologene: 74523
Galnt5
Name: polypeptide N-acetylgalactosaminyltransferase 5
Synonyms: ppGaNTase-T5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241391
HGNC: HGNC:4127
Homologene: 8733
Flrt1
Name: fibronectin leucine rich transmembrane protein 1
Synonyms: D630040I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 396184
VEGA: 19
HGNC: HGNC:3760
Homologene: 40864
Cul7
Name: cullin 7
Synonyms: 2510004L20Rik, p185, C230011P08Rik, p193
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 66515
Homologene: 56683
Msh4
Name: mutS homolog 4
Synonyms: 4930485C04Rik, mMsh4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 55993
HGNC: HGNC:7327
Homologene: 1830
Dchs1
Name: dachsous cadherin related 1
Synonyms: C130033F22Rik, 3110041P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233651
Homologene: 2771
Pkhd1
Name: polycystic kidney and hepatic disease 1
Synonyms: FPC, tigmin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241035
HGNC: HGNC:9016
Homologene: 16336
1700022I11Rik
Name: RIKEN cDNA 1700022I11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67317
Homologene: 52406
Ogdhl
Name: oxoglutarate dehydrogenase-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239017
VEGA: 14
Homologene: 56801
Ndst2
Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
Synonyms: [Heparan sulfate]-glucosamine N-sulfotransferase, Mndns, glucosaminyl N-deacetylase/N-sulphotransferase-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 17423
VEGA: 14
HGNC: HGNC:7681
Homologene: 20803
Dlec1
Name: deleted in lung and esophageal cancer 1
Synonyms: D630005C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320256
HGNC: HGNC:2899
Homologene: 84733
Vmn2r114
Name: vomeronasal 2, receptor 114
Synonyms: EG666002
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 666002
Homologene: 86604
Olfr593
Name: olfactory receptor 593
Synonyms: MOR24-2, GA_x6K02T2PBJ9-5927412-5928362
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258378
Homologene: 27147
Slc26a4
Name: solute carrier family 26, member 4
Synonyms: Pds, pendrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 23985
VEGA: 12
HGNC: HGNC:8818
Homologene: 20132
Sytl1
Name: synaptotagmin-like 1
Synonyms: Slp1, PSGL-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 269589
Homologene: 12853
Mrgpra4
Name: MAS-related GPR, member A4
Synonyms: MrgA4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 235854
Homologene: 131159
Olfr769
Name: olfactory receptor 769
Synonyms: MOR114-14, GA_x6K02T2PULF-10797876-10796938
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 257667
Homologene: 121502
Vmn2r23
Name: vomeronasal 2, receptor 23
Synonyms: EG435916
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 435916
Homologene: 135826
A630073D07Rik
Name: RIKEN cDNA A630073D07 gene
Synonyms: LOC381819
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 381819
Ifnlr1
Name: interferon lambda receptor 1
Synonyms: IFNLR1, CRF2-12, Il28ra
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242700
Homologene: 52086
Alms1-ps1
Name: ALMS1, centrosome and basal body associated, pseudogene 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 100043493
Myct1
Name: myc target 1
Synonyms: MT-MC1, Mtmc1, 1110020B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 68632
VEGA: 10
Homologene: 11833
Apol8
Name: apolipoprotein L 8
Synonyms: Apol2, 9830006J20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239552
VEGA: 15
HGNC: HGNC:619
Homologene: 12785
Mpp1
Name: membrane protein, palmitoylated
Synonyms: erythrocyte protein p55, C130070C03Rik, p55, 55kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 17524
HGNC: HGNC:7219
Homologene: 1826
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 20,524,230 bp
  • T to A, chromosome 2 at 57,998,980 bp
  • G to A, chromosome 3 at 153,879,367 bp
  • T to A, chromosome 4 at 42,970,952 bp
  • A to T, chromosome 4 at 133,253,225 bp
  • T to A, chromosome 4 at 135,705,634 bp
  • A to C, chromosome 5 at 32,901,470 bp
  • A to T, chromosome 5 at 44,047,629 bp
  • A to T, chromosome 5 at 142,658,234 bp
  • T to A, chromosome 6 at 85,727,685 bp
  • T to C, chromosome 6 at 116,244,616 bp
  • C to T, chromosome 6 at 123,713,451 bp
  • G to A, chromosome 6 at 132,626,557 bp
  • T to C, chromosome 7 at 37,965,500 bp
  • C to T, chromosome 7 at 47,980,980 bp
  • C to T, chromosome 7 at 103,212,798 bp
  • G to A, chromosome 7 at 105,764,984 bp
  • T to A, chromosome 9 at 119,105,960 bp
  • G to T, chromosome 10 at 5,604,261 bp
  • T to A, chromosome 10 at 129,112,078 bp
  • A to G, chromosome 12 at 31,549,911 bp
  • G to A, chromosome 14 at 20,729,579 bp
  • A to T, chromosome 14 at 32,339,925 bp
  • A to C, chromosome 15 at 77,749,851 bp
  • A to G, chromosome 16 at 30,308,375 bp
  • T to G, chromosome 17 at 23,310,594 bp
  • T to C, chromosome 17 at 29,298,664 bp
  • T to A, chromosome 17 at 46,663,190 bp
  • A to T, chromosome 19 at 7,096,179 bp
  • T to C, chromosome X at 75,125,733 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0677 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038862-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.