Strain Name:
C57BL/6J-MtgxR0725Btlr/Mmmh
Stock Number:
038907-MU
Citation ID:
RRID:MMRRC_038907-MU
Other Names:
R0725 (G1), C57BL/6J-MtgxR0725Btlr
Major Collection:

Gene Information

Cep55
Name: centrosomal protein 55
Synonyms: 1200008O12Rik, 2700032M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 74107
VEGA: 19
HGNC: HGNC:1161
Homologene: 10019
Pcm1
Name: pericentriolar material 1
Synonyms: 2600002H09Rik, C030044G17Rik, 9430077F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 18536
HGNC: HGNC:8727
Homologene: 4518
Xpnpep3
Name: X-prolyl aminopeptidase 3, mitochondrial
Synonyms: E430012M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 321003
Homologene: null
Stx12
Name: syntaxin 12
Synonyms: syntaxin 13, Stx13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100226
Homologene: 128192
Nfyc
Name: nuclear transcription factor-Y gamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 18046
HGNC: HGNC:7806
Homologene: 7440
Kntc1
Name: kinetochore associated 1
Synonyms: jgl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 208628
Homologene: 32227
Osbpl8
Name: oxysterol binding protein-like 8
Synonyms: ORP-8, D330025H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 237542
VEGA: 10
Homologene: 68813
Ncbp1
Name: nuclear cap binding protein subunit 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 433702
HGNC: HGNC:7658
Homologene: 1859
Pdcd11
Name: programmed cell death 11
Synonyms: ALG-4, 1110021I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 18572
VEGA: 19
Homologene: 74968
Clptm1l
Name: CLPTM1-like
Synonyms: C130052I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218335
VEGA: 13
Homologene: 12767
Ccnk
Name: cyclin K
Synonyms: CPR4, CycK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 12454
VEGA: 12
HGNC: HGNC:1596
Homologene: 14748
Crygb
Name: crystallin, gamma B
Synonyms: DGcry-3, Cryg-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12965
HGNC: HGNC:2409
Homologene: 3816
Dock7
Name: dedicator of cytokinesis 7
Synonyms: m, 3110056M06Rik, LOC242555
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 67299
Homologene: 23566
Atp13a3
Name: ATPase type 13A3
Synonyms: LOC224087, LOC385637, LOC224088
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224088
Homologene: 23455
Rbm33
Name: RNA binding motif protein 33
Synonyms: 3200001K10Rik, 6430512A10Rik, Prr8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 381626
Homologene: 137386
Fgfrl1
Name: fibroblast growth factor receptor-like 1
Synonyms: FGFR5, FGFR5beta, fibroblast growth factor receptor 5, FGFR5gamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 116701
HGNC: HGNC:3693
Homologene: 11067
Muc20
Name: mucin 20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224116
Homologene: 17135
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: 4432416O06Rik, DHC2, b2b414Clo, Dnchc2, m407Asp, m152Asp, D030010H02Rik, D330044F14Rik, DHC1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Vezf1
Name: vascular endothelial zinc finger 1
Synonyms: db1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 22344
Homologene: 5175
Asph
Name: aspartate-beta-hydroxylase
Synonyms: Junctin, cI-37, junctate, calsequestrin-binding protein, aspartyl beta-hydroxylase, 3110001L23Rik, jumbug, 2310005F16Rik, BAH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 65973
HGNC: HGNC:757
Homologene: 20910
Gzf1
Name: GDNF-inducible zinc finger protein 1
Synonyms: Zfp336, 8430437G08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 74533
Homologene: 11200
Cpped1
Name: calcineurin-like phosphoesterase domain containing 1
Synonyms: C530044N13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 223978
Homologene: 10142
Heatr5b
Name: HEAT repeat containing 5B
Synonyms: D330050P16Rik, A230048G03Rik, 2010013B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 320473
VEGA: 17
Homologene: 25536
Zfp287
Name: zinc finger protein 287
Synonyms: B230333C16Rik, SKAT-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 170740
Homologene: 23244
Pkp1
Name: plakophilin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18772
HGNC: HGNC:9023
Homologene: 253
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Ush2a
Name: usherin
Synonyms: Ush2a, Ushrn, MUSH2A, A930037M10Rik, A930011D15Rik, LOC269160, LOC381317
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 22283
Homologene: 66151
Cyp4b1
Name: cytochrome P450, family 4, subfamily b, polypeptide 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 13120
HGNC: HGNC:2644
Homologene: 128045
Cacna1s
Name: calcium channel, voltage-dependent, L type, alpha 1S subunit
Synonyms: sj, DHPR alpha1s, muscle dysgenesis, fmd, Cchl1a3, mdg, Cav1.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12292
HGNC: HGNC:1397
Homologene: 37257
Slc3a1
Name: solute carrier family 3, member 1
Synonyms: D2H, NTAA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 20532
VEGA: 17
Homologene: 37289
Macc1
Name: metastasis associated in colon cancer 1
Synonyms: 4732474O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238455
Homologene: 18813
Selenbp2
Name: selenium binding protein 2
Synonyms: AP56, Lpsb2, acetaminophen-binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20342
Homologene: 2930
Yipf2
Name: Yip1 domain family, member 2
Synonyms: 1300010K09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74766
VEGA: 9
Homologene: 23430
Tas2r125
Name: taste receptor, type 2, member 125
Synonyms: mGR25, T2R26, Tas2r25, mt2r59
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 387352
HGNC: null
Homologene: 87294
Cfap300
Name: cilia and flagella associated protein 300
Synonyms: 9230110C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 234912
VEGA: 9
Homologene: 13163
Tmed11
Name: transmembrane p24 trafficking protein 11
Synonyms: 1810008K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 67366
Homologene: 48721
Psmc4
Name: proteasome (prosome, macropain) 26S subunit, ATPase, 4
Synonyms: MIP224, CIP21, CAR interacting protein 21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 23996
HGNC: HGNC:9551
Homologene: 4744
Zfp110
Name: zinc finger protein 110
Synonyms: NRIF, 2900024E01Rik, Nrif1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 65020
Homologene: 129707
Dsel
Name: dermatan sulfate epimerase-like
Synonyms: DS-epi2, 9330132E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 319901
Homologene: 12964
Fam129a
Name: family with sequence similarity 129, member A
Synonyms: Niban
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 63913
Homologene: 62170
Olfr561
Name: olfactory receptor 561
Synonyms: MOR14-2, GA_x6K02T2PBJ9-5491151-5492095
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259096
HGNC: null
Homologene: 133029
Cfh
Name: complement component factor h
Synonyms: Sas1, Sas-1, Mud-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12628
HGNC: HGNC:4883
Homologene: 20086
Tchp
Name: trichoplein, keratin filament binding
Synonyms: A930031F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 77832
Homologene: 12686
Cntnap5a
Name: contactin associated protein-like 5A
Synonyms: Caspr5-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 636808
Homologene: 43974
Dll4
Name: delta like canonical Notch ligand 4
Synonyms: Delta4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 54485
HGNC: HGNC:2910
Homologene: 10411
Cyp3a25
Name: cytochrome P450, family 3, subfamily a, polypeptide 25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 56388
HGNC: null
Homologene: 135775
Mpp4
Name: membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
Synonyms: DLG6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227157
Homologene: 23296
Nfxl1
Name: nuclear transcription factor, X-box binding-like 1
Synonyms: LOC381696, TCF9, 1700012H24Rik, D430033A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100978
Homologene: 26752
Olfr972
Name: olfactory receptor 972
Synonyms: MOR171-17, GA_x6K02T2PVTD-33572803-33573747
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258603
VEGA: 9
HGNC: null
Homologene: 121532
Fam167b
Name: family with sequence similarity 167, member B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230766
Homologene: 13085
4930562F07Rik
Name: RIKEN cDNA 4930562F07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 75255
HGNC: null
Homologene: null
Pigm
Name: phosphatidylinositol glycan anchor biosynthesis, class M
Synonyms: C920011G20Rik, 4933437L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 67556
Homologene: 6274
Pheta1
Name: PH domain containing endocytic trafficking adaptor 1
Synonyms: Fam109a, Ses1, A230106M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231717
Homologene: 16966
Pex12
Name: peroxisomal biogenesis factor 12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 103737
HGNC: HGNC:8854
Homologene: 240
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 59,121,422 bp
  • T to C, chromosome 1 at 65,081,941 bp
  • T to C, chromosome 1 at 111,859,952 bp
  • A to G, chromosome 1 at 116,292,476 bp
  • G to T, chromosome 1 at 135,880,740 bp
  • T to C, chromosome 1 at 136,098,526 bp
  • A to G, chromosome 1 at 140,157,343 bp
  • A to G, chromosome 1 at 151,706,015 bp
  • A to G, chromosome 1 at 160,077,483 bp
  • A to G, chromosome 1 at 172,376,817 bp
  • G to A, chromosome 1 at 188,951,525 bp
  • C to T, chromosome 2 at 76,748,310 bp
  • T to C, chromosome 2 at 119,332,689 bp
  • C to T, chromosome 2 at 148,684,649 bp
  • G to T, chromosome 3 at 94,697,502 bp
  • C to T, chromosome 4 at 9,542,275 bp
  • A to G, chromosome 4 at 46,152,056 bp
  • T to C, chromosome 4 at 98,945,291 bp
  • T to C, chromosome 4 at 115,626,827 bp
  • G to T, chromosome 4 at 120,768,734 bp
  • C to A, chromosome 4 at 129,578,285 bp
  • A to C, chromosome 4 at 132,857,390 bp
  • T to C, chromosome 5 at 28,394,483 bp
  • A to T, chromosome 5 at 72,559,130 bp
  • T to A, chromosome 5 at 108,704,673 bp
  • T to A, chromosome 5 at 108,778,989 bp
  • C to A, chromosome 5 at 114,719,621 bp
  • T to A, chromosome 5 at 121,853,251 bp
  • T to C, chromosome 5 at 123,769,704 bp
  • A to G, chromosome 5 at 145,994,936 bp
  • G to T, chromosome 6 at 132,910,122 bp
  • A to T, chromosome 7 at 12,836,363 bp
  • T to C, chromosome 7 at 28,048,862 bp
  • T to A, chromosome 7 at 102,774,532 bp
  • G to C, chromosome 8 at 41,287,811 bp
  • C to A, chromosome 9 at 7,015,497 bp
  • A to T, chromosome 9 at 8,027,143 bp
  • G to C, chromosome 9 at 21,592,223 bp
  • A to T, chromosome 9 at 39,873,347 bp
  • T to C, chromosome 10 at 111,286,240 bp
  • A to T, chromosome 11 at 62,714,213 bp
  • G to T, chromosome 11 at 83,298,034 bp
  • T to C, chromosome 11 at 88,073,330 bp
  • T to C, chromosome 12 at 108,195,575 bp
  • C to A, chromosome 12 at 119,447,516 bp
  • A to G, chromosome 13 at 73,606,343 bp
  • T to C, chromosome 15 at 81,430,842 bp
  • C to A, chromosome 16 at 11,828,450 bp
  • T to C, chromosome 16 at 30,351,387 bp
  • C to T, chromosome 16 at 32,793,488 bp
  • T to A, chromosome 17 at 78,796,396 bp
  • G to A, chromosome 17 at 85,060,835 bp
  • T to C, chromosome 19 at 38,060,174 bp
  • A to G, chromosome 19 at 47,127,291 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0725 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038907-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.