Strain Name:
C57BL/6J-MtgxR0735Btlr/Mmmh
Stock Number:
038916-MU
Citation ID:
RRID:MMRRC_038916-MU
Other Names:
R0735 (G1), C57BL/6J-MtgxR0735Btlr
Major Collection:

Gene Information

Chrnb4
Name: cholinergic receptor, nicotinic, beta polypeptide 4
Synonyms: Acrb-4, Acrb4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 108015
VEGA: 9
HGNC: HGNC:1964
Homologene: 20196
Sod2
Name: superoxide dismutase 2, mitochondrial
Synonyms: Sod-2, MnSOD, manganese superoxide dismutase, manganese SOD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 20656
VEGA: 17
Homologene: 530
Trdmt1
Name: tRNA aspartic acid methyltransferase 1
Synonyms: Rnmt2, Dnmt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 13434
HGNC: HGNC:2977
Homologene: 3249
Fdft1
Name: farnesyl diphosphate farnesyl transferase 1
Synonyms: Ss, SQS, squalene synthase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 14137
VEGA: 14
HGNC: HGNC:3629
Homologene: 3281
Mtbp
Name: Mdm2, transformed 3T3 cell double minute p53 binding protein
Synonyms: MDM2BP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 105837
HGNC: HGNC:7417
Homologene: 11102
Cpne1
Name: copine I
Synonyms: 1810028N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 266692
HGNC: HGNC:2314
Homologene: 36501
Camsap2
Name: calmodulin regulated spectrin-associated protein family, member 2
Synonyms: 4930541M15Rik, Camsap1l1, 1600013L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 67886
Homologene: 18927
Kcnk1
Name: potassium channel, subfamily K, member 1
Synonyms: TWIK-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 16525
HGNC: HGNC:6272
Homologene: 1691
Trip4
Name: thyroid hormone receptor interactor 4
Synonyms: 4930558E03Rik, ASC-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 56404
Homologene: 9426
Actr8
Name: ARP8 actin-related protein 8
Synonyms: ARP8, 5730542K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 56249
VEGA: 14
Homologene: 11286
Frs2
Name: fibroblast growth factor receptor substrate 2
Synonyms: Frs2alpha, C330018A15Rik, SNT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 327826
VEGA: 10
Homologene: 4846
Osbpl2
Name: oxysterol binding protein-like 2
Synonyms: ORP-2, C130070J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228983
Homologene: 77324
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: Dnahc7, Dnahc7a, LOC381341
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 627872
Homologene: 41287
Myt1
Name: myelin transcription factor 1
Synonyms: NZF-2a, Nztf2, Nzf2, NZF-2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17932
HGNC: HGNC:7622
Homologene: 3332
Fam193a
Name: family with sequence homology 193, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231128
Homologene: 2746
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: p600, A930005E13Rik, 1810009A16Rik, LOC381562, D930005K06Rik, Zubr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 69116
Homologene: 10804
Cul7
Name: cullin 7
Synonyms: p185, p193, 2510004L20Rik, C230011P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 66515
Homologene: 56683
Rsrp1
Name: arginine/serine rich protein 1
Synonyms: D4Ucla2, D4Wsu53e, 2700043I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 27981
Dgke
Name: diacylglycerol kinase, epsilon
Synonyms: DAGK6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 56077
HGNC: HGNC:2852
Homologene: 2705
Egln1
Name: egl-9 family hypoxia-inducible factor 1
Synonyms: Hif-p4h-2, Phd2, ORF13, SM-20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 112405
HGNC: HGNC:1232
Homologene: 56936
Gpr107
Name: G protein-coupled receptor 107
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 277463
Homologene: 81077
Fem1c
Name: fem-1 homolog c (C.elegans)
Synonyms: 3632443A22Rik, 2610312A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 240263
Homologene: 10606
Akap11
Name: A kinase (PRKA) anchor protein 11
Synonyms: 6330501D17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 219181
HGNC: HGNC:369
Homologene: 8279
St3gal1
Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 1
Synonyms: Siat4, CMP-N-acetylneuraminate: [beta-galactosidase alpha-2,3] sialytransferase, ST3GalI, Siat4a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 20442
VEGA: 15
Homologene: 7540
Myo7a
Name: myosin VIIA
Synonyms: USH1B, Hdb, Myo7, polka, nmf371
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 17921
HGNC: HGNC:7606
Homologene: 219
Cubn
Name: cubilin (intrinsic factor-cobalamin receptor)
Synonyms: D2Wsu88e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 65969
HGNC: HGNC:2548
Homologene: 37434
Mlkl
Name: mixed lineage kinase domain-like
Synonyms: 9130019I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 74568
Homologene: 77416
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Klb
Name: klotho beta
Synonyms: betaKlotho
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 83379
Homologene: 12820
Dhx36
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 36
Synonyms: Ddx36, 2810407E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 72162
Homologene: 6356
Ush2a
Name: usherin
Synonyms: Ush2a, Ushrn, MUSH2A, A930037M10Rik, A930011D15Rik, LOC269160, LOC381317
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 22283
Homologene: 66151
Trim58
Name: tripartite motif-containing 58
Synonyms: LOC386443, LOC216781
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216781
Homologene: 9135
Ogfrl1
Name: opioid growth factor receptor-like 1
Synonyms: 2210417C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 70155
Homologene: 11595
Plb1
Name: phospholipase B1
Synonyms: 4632413E21Rik, 4930433E17Rik, 4930539A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 665270
Homologene: 82108
Ptpro
Name: protein tyrosine phosphatase, receptor type, O
Synonyms: D28, PTP-U2, GLEPP1, PTP-oc, PTPROt, Ptpn15, PTP-phi, PTP-BK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 19277
HGNC: HGNC:9678
Homologene: 21564
9930021J03Rik
Name: RIKEN cDNA 9930021J03 gene
Synonyms: Gm9832
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 240613
Homologene: 19046
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20192
Homologene: 68151
Astn1
Name: astrotactin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 11899
HGNC: HGNC:773
Homologene: 7233
Mroh2a
Name: maestro heat-like repeat family member 2A
Synonyms: ENSMUSG00000044873, Heatr7b1, OTTMUSG00000020804
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 100040766
Homologene: 85300
Scara5
Name: scavenger receptor class A, member 5
Synonyms: 4933425F03Rik, 4932433F15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 71145
Homologene: 12556
Trip6
Name: thyroid hormone receptor interactor 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 22051
Homologene: 37757
Xab2
Name: XPA binding protein 2
Synonyms: 0610041O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 67439
Homologene: 5738
Tdrd1
Name: tudor domain containing 1
Synonyms: MTR-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 83561
Homologene: 12850
Thbs2
Name: thrombospondin 2
Synonyms: Thrombospondin-2, Thbs-2, TSP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 21826
VEGA: 17
Homologene: 2438
Vmn2r53
Name: vomeronasal 2, receptor 53
Synonyms: EG637908
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 637908
Homologene: 104040
Adam10
Name: a disintegrin and metallopeptidase domain 10
Synonyms: 1700031C13Rik, kuzbanian, kuz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 11487
HGNC: HGNC:188
Homologene: 865
Rims4
Name: regulating synaptic membrane exocytosis 4
Synonyms: Rim4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241770
Homologene: 18123
Stat6
Name: signal transducer and activator of transcription 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 20852
Homologene: 2373
Rbsn
Name: rabenosyn, RAB effector
Synonyms: Rabenosyn-5, 5330426D11Rik, Zfyve20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 78287
Homologene: 41477
Vmn2r7
Name: vomeronasal 2, receptor 7
Synonyms: 4933425M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 319217
Homologene: 129754
Cyp2c23
Name: cytochrome P450, family 2, subfamily c, polypeptide 23
Synonyms: Cyp2c44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226143
Homologene: 115563
Wnt7b
Name: wingless-type MMTV integration site family, member 7B
Synonyms: Wnt-7b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 22422
VEGA: 15
Homologene: 22531
Tor1a
Name: torsin family 1, member A (torsin A)
Synonyms: torsinA, Dyt1, DQ2, Tor1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 30931
HGNC: HGNC:3098
Homologene: 37263
Hsp90b1
Name: heat shock protein 90, beta (Grp94), member 1
Synonyms: Tra-1, endoplasmin, GRP94, Targ2, 90 kDa, Tra1, tumor rejection antigen (gp96) 1, ERp99, gp96
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 22027
Homologene: 2476
Gm15448
Name: predicted gene 15448
Synonyms: ENSMUSG00000074419
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100041146
HGNC: HGNC:6607
Homologene: 134028
Edil3
Name: EGF-like repeats and discoidin I-like domains 3
Synonyms: developmental endothelial locus-1, Del1, Del-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 13612
HGNC: HGNC:3173
Homologene: 21166
Vmn1r29
Name: vomeronasal 1 receptor 29
Synonyms: V1rc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 113859
Homologene: 123821
Slc7a11
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
Synonyms: System xc, 9930009M05Rik, xc, xCT, sut
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 26570
Homologene: 22684
B3galt1
Name: UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
Synonyms: 6330417G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 26877
HGNC: HGNC:916
Homologene: 41362
Cxcl15
Name: chemokine (C-X-C motif) ligand 15
Synonyms: weche, lungkine, Scyb15, Il8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20309
B4galnt4
Name: beta-1,4-N-acetyl-galactosaminyl transferase 4
Synonyms: LOC381951
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 330671
Homologene: 27982
Olfr418
Name: olfactory receptor 418
Synonyms: MOR267-12P, Olfr418-ps1, MOR267-8, GA_x6K02T2R7CC-581296-580364, GA_x6K02T2P20D-20826777-20827719, Olfr1403
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 258645
HGNC: HGNC:8175
Homologene: 8218
Zfp663
Name: zinc finger protein 663
Synonyms: Gm1008, LOC381405
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 381405
Homologene: 128277
Gpr153
Name: G protein-coupled receptor 153
Synonyms: 1110065N12Rik, PGR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100129
Homologene: 18662
Lat2
Name: linker for activation of T cells family, member 2
Synonyms: Wbscr5, Wbscr15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 56743
Homologene: 11297
Olfr661
Name: olfactory receptor 661
Synonyms: GA_x6K02T2PBJ9-7316375-7317334, MOR40-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258743
Homologene: 17376
Adgra2
Name: adhesion G protein-coupled receptor A2
Synonyms: 9530074E10Rik, 8430414O08Rik, Tem5, Gpr124
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 78560
Homologene: 13112
Spesp1
Name: sperm equatorial segment protein 1
Synonyms: 4921508E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 66712
VEGA: 9
Homologene: 49838
H2-Q7
Name: histocompatibility 2, Q region locus 7
Synonyms: H-2Q7, Ped, Qa7, Qa-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 15018
HGNC: HGNC:4931
Homologene: 128352
Rps6kb2
Name: ribosomal protein S6 kinase, polypeptide 2
Synonyms: S6K2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 58988
Homologene: 68374
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 23,375,754 bp
  • C to T, chromosome 1 at 53,544,511 bp
  • G to A, chromosome 1 at 88,243,950 bp
  • A to G, chromosome 1 at 136,292,888 bp
  • A to T, chromosome 1 at 158,472,389 bp
  • A to G, chromosome 1 at 173,271,002 bp
  • G to A, chromosome 1 at 188,864,693 bp
  • G to A, chromosome 2 at 13,491,689 bp
  • T to G, chromosome 2 at 13,523,438 bp
  • A to G, chromosome 2 at 30,963,838 bp
  • T to A, chromosome 2 at 31,171,994 bp
  • A to C, chromosome 2 at 68,118,579 bp
  • T to A, chromosome 2 at 76,715,195 bp
  • T to C, chromosome 2 at 112,732,982 bp
  • A to G, chromosome 2 at 156,078,750 bp
  • C to T, chromosome 2 at 163,863,929 bp
  • A to G, chromosome 2 at 165,359,075 bp
  • A to G, chromosome 2 at 180,150,290 bp
  • G to A, chromosome 2 at 181,807,387 bp
  • C to T, chromosome 3 at 50,424,096 bp
  • T to A, chromosome 3 at 62,472,729 bp
  • C to T, chromosome 3 at 64,716,367 bp
  • C to T, chromosome 4 at 134,924,257 bp
  • T to A, chromosome 4 at 139,428,028 bp
  • T to A, chromosome 4 at 152,279,373 bp
  • C to T, chromosome 5 at 32,284,920 bp
  • T to C, chromosome 5 at 34,439,378 bp
  • T to C, chromosome 5 at 65,379,727 bp
  • T to C, chromosome 5 at 90,801,294 bp
  • T to C, chromosome 5 at 134,606,783 bp
  • T to C, chromosome 5 at 137,310,821 bp
  • G to T, chromosome 6 at 58,307,732 bp
  • T to C, chromosome 6 at 92,189,693 bp
  • T to A, chromosome 6 at 137,443,594 bp
  • T to C, chromosome 7 at 3,821,782 bp
  • A to G, chromosome 7 at 12,581,780 bp
  • A to G, chromosome 7 at 98,081,180 bp
  • A to T, chromosome 7 at 104,688,819 bp
  • A to G, chromosome 7 at 141,064,323 bp
  • G to A, chromosome 8 at 3,613,649 bp
  • G to T, chromosome 8 at 27,117,318 bp
  • A to T, chromosome 8 at 111,327,801 bp
  • A to G, chromosome 8 at 124,948,495 bp
  • C to A, chromosome 8 at 126,025,289 bp
  • A to G, chromosome 9 at 55,043,800 bp
  • A to T, chromosome 9 at 62,272,685 bp
  • C to T, chromosome 9 at 65,884,918 bp
  • G to A, chromosome 9 at 70,748,251 bp
  • A to T, chromosome 10 at 86,695,748 bp
  • T to A, chromosome 10 at 117,074,582 bp
  • A to T, chromosome 10 at 127,658,241 bp
  • T to C, chromosome 11 at 58,651,393 bp
  • A to G, chromosome 11 at 89,060,075 bp
  • G to T, chromosome 13 at 89,177,178 bp
  • T to A, chromosome 14 at 29,989,712 bp
  • A to T, chromosome 14 at 63,163,420 bp
  • A to G, chromosome 14 at 65,731,019 bp
  • A to T, chromosome 14 at 78,510,078 bp
  • T to A, chromosome 15 at 55,562,942 bp
  • C to A, chromosome 15 at 67,113,687 bp
  • G to A, chromosome 15 at 85,537,495 bp
  • A to T, chromosome 17 at 13,010,564 bp
  • A to G, chromosome 17 at 14,679,815 bp
  • T to G, chromosome 17 at 35,440,186 bp
  • T to A, chromosome 17 at 46,663,190 bp
  • G to A, chromosome 18 at 46,505,160 bp
  • C to A, chromosome 19 at 4,157,883 bp
  • A to T, chromosome 19 at 29,717,638 bp
  • A to T, chromosome 19 at 44,016,810 bp
  • A to T, chromosome 19 at 56,865,978 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0735 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038916-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.