Strain Name:
C57BL/6J-MtgxR0787Btlr/Mmmh
Stock Number:
038967-MU
Citation ID:
RRID:MMRRC_038967-MU
Other Names:
R0787 (G1), C57BL/6J-MtgxR0787Btlr
Major Collection:

Gene Information

Pik3r1
Name: phosphoinositide-3-kinase regulatory subunit 1
Synonyms: p85alpha, p55alpha, p50alpha, PI3K
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18708
HGNC: HGNC:8979
Homologene: 7889
Lrrn3
Name: leucine rich repeat protein 3, neuronal
Synonyms: NLRR-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 16981
VEGA: 12
Homologene: 36315
Pcdh9
Name: protocadherin 9
Synonyms: C630029H24Rik, A730003J17Rik, 1500001L12Rik, LOC382930, C530050I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 211712
HGNC: HGNC:8661
Homologene: 10698
Epb41l1
Name: erythrocyte membrane protein band 4.1 like 1
Synonyms: Epb4.1l1, 4.1N
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 13821
HGNC: HGNC:3378
Homologene: 8126
Fgd4
Name: FYVE, RhoGEF and PH domain containing 4
Synonyms: ZFYVE6, 9330209B17Rik, Frabin-gamma, Frabin-beta, Frabin-alpha, Frabin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224014
Homologene: 26727
Hsp90ab1
Name: heat shock protein 90 alpha (cytosolic), class B member 1
Synonyms: Hsp84-1, Hspcb, Hsp84, Hsp90, C81438
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15516
HGNC: HGNC:5258
Homologene: 74306
Denn2b
Name: DENN domain containing 2B
Synonyms: St5, 2010004M01Rik, 2610305K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76954
Homologene: 3951
Shmt1
Name: serine hydroxymethyltransferase 1 (soluble)
Synonyms: mshmt2, Shmt, mshmt, mshmt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20425
Homologene: 3074
Wdfy3
Name: WD repeat and FYVE domain containing 3
Synonyms: D5Ertd66e, Alfy, Bwf1, 2610509D04Rik, Bchs, Ggtb3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72145
Homologene: 22855
Armc9
Name: armadillo repeat containing 9
Synonyms: 4930438O05Rik, 4831423D23Rik, 3830422A13Rik, 5730415N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 78795
Homologene: 11847
Phf20l1
Name: PHD finger protein 20-like 1
Synonyms: E130113K22Rik, CGI-72
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239510
VEGA: 15
Homologene: 9341
Kntc1
Name: kinetochore associated 1
Synonyms: jgl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 208628
Homologene: 32227
Zfr
Name: zinc finger RNA binding protein
Synonyms: C920030H05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 22763
Homologene: 8009
Ankfy1
Name: ankyrin repeat and FYVE domain containing 1
Synonyms: Ankhzn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11736
Homologene: 9491
Tmem87a
Name: transmembrane protein 87A
Synonyms: A930025J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 211499
Homologene: 9165
Zfp407
Name: zinc finger protein 407
Synonyms: 6430585N13Rik, LOC381139, LOC240469
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240476
Homologene: 86402
Tep1
Name: telomerase associated protein 1
Synonyms: Tp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 21745
VEGA: 14
Homologene: 5157
Tiam1
Name: T cell lymphoma invasion and metastasis 1
Synonyms: D16Ium10e, D16Ium10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 21844
Homologene: 2443
Rasal2
Name: RAS protein activator like 2
Synonyms: A330066M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226525
HGNC: HGNC:9874
Homologene: 35217
Ppp1r7
Name: protein phosphatase 1, regulatory subunit 7
Synonyms: 2310014J01Rik, SDS22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 66385
HGNC: HGNC:9295
Homologene: 2032
Pirb
Name: paired Ig-like receptor B
Synonyms: Gp91, Lilrb3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18733
HGNC: HGNC:6607
Homologene: 134028
Ankrd13c
Name: ankyrin repeat domain 13c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 433667
Homologene: 41804
Ubr3
Name: ubiquitin protein ligase E3 component n-recognin 3
Synonyms: 4833421P10Rik, Zfp650, A130030D10Rik, 1110059H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68795
Homologene: 52092
Fat1
Name: FAT atypical cadherin 1
Synonyms: 2310038E12Rik, mFat1, Fath
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14107
HGNC: HGNC:3595
Homologene: 66302
Ptov1
Name: prostate tumor over expressed gene 1
Synonyms: Gcap3, 1110030G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 84113
HGNC: HGNC:9632
Homologene: 9687
Tecpr2
Name: tectonin beta-propeller repeat containing 2
Synonyms: 4930573I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 104859
VEGA: 12
Homologene: 8897
Ubxn7
Name: UBX domain protein 7
Synonyms: Ubxd7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224111
VEGA: 16
Homologene: 45585
Lig1
Name: ligase I, DNA, ATP-dependent
Synonyms: LigI, mLigI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16881
HGNC: HGNC:6598
Homologene: 197
Col12a1
Name: collagen, type XII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12816
HGNC: HGNC:2188
Homologene: 3217
Itga4
Name: integrin alpha 4
Synonyms: VLA-4 receptor, alpha 4 subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16401
HGNC: HGNC:6140
Homologene: 37364
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: fibrocystin L, D86 mRNA, PKHDL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 192190
Homologene: 16332
Adamts16
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 271127
Homologene: 15146
Naip1
Name: NLR family, apoptosis inhibitory protein 1
Synonyms: Birc1a, Naip, D13Lsd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17940
VEGA: 13
HGNC: HGNC:7634
Homologene: 113589
Abca8a
Name: ATP-binding cassette, sub-family A (ABC1), member 8a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217258
HGNC: HGNC:38
Homologene: 131160
Hltf
Name: helicase-like transcription factor
Synonyms: Snf2l3, P113, Smarca3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20585
Homologene: 30136
Agap2
Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
Synonyms: Centg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216439
VEGA: 10
Homologene: 86815
Cyp2c54
Name: cytochrome P450, family 2, subfamily c, polypeptide 54
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 404195
VEGA: 19
Homologene: 137231
Vmn2r13
Name: vomeronasal 2, receptor 13
Synonyms: Gm4867
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231589
Homologene: 129606
Pkd1l2
Name: polycystic kidney disease 1 like 2
Synonyms: 1700126L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 76645
Homologene: 124481
Tbc1d4
Name: TBC1 domain family, member 4
Synonyms: AS160, 5930406J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 210789
Homologene: 45451
Phgdh
Name: 3-phosphoglycerate dehydrogenase
Synonyms: 3-PGDH, SERA, A10, PGAD, 3PGDH, PGD, PGDH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 236539
HGNC: HGNC:8923
Homologene: 39318
Abcc2
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Synonyms: Mrp2, multidrug resistance protein 2, Cmoat
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 12780
HGNC: HGNC:53
Homologene: 68052
Arhgap40
Name: Rho GTPase activating protein 40
Synonyms: Gm14203
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 545481
Homologene: 53500
Armc12
Name: armadillo repeat containing 12
Synonyms: 4930511I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 67645
Homologene: 12168
Mtmr10
Name: myotubularin related protein 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233315
Homologene: 9822
Ehbp1l1
Name: EH domain binding protein 1-like 1
Synonyms: G430002G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 114601
VEGA: 19
Homologene: 136059
Prr22
Name: proline rich 22
Synonyms: LOC224908, Gm546
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 100504446
Homologene: 51921
Fam217b
Name: family with sequence similarity 217, member B
Synonyms: 9030418K01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71532
Homologene: 49697
E130311K13Rik
Name: RIKEN cDNA E130311K13 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329659
Homologene: 35262
Czib
Name: CXXC motif containing zinc binding protein
Synonyms: 0610037L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74098
Homologene: 41206
Isg15
Name: ISG15 ubiquitin-like modifier
Synonyms: G1p2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100038882
VEGA: 4
HGNC: HGNC:4053
Homologene: 48326
Zdhhc3
Name: zinc finger, DHHC domain containing 3
Synonyms: 2210017C02Rik, 1810006O10Rik, Zfp373, 1110020O22Rik, GODZ
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 69035
Homologene: 9582
Olfr770
Name: olfactory receptor 770
Synonyms: MOR114-5, GA_x6K02T2PULF-10819232-10818297
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258862
Homologene: 27285
1700001F09Rik
Name: RIKEN cDNA 1700001F09 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71826
Homologene: 128452
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 86,202,505 bp
  • A to G, chromosome 1 at 93,364,956 bp
  • A to G, chromosome 1 at 157,158,696 bp
  • T to C, chromosome 2 at 69,951,421 bp
  • C to T, chromosome 2 at 79,279,153 bp
  • T to C, chromosome 2 at 120,370,484 bp
  • A to G, chromosome 2 at 156,494,090 bp
  • T to C, chromosome 2 at 158,547,790 bp
  • T to A, chromosome 2 at 178,420,909 bp
  • A to T, chromosome 3 at 20,106,446 bp
  • A to T, chromosome 3 at 63,920,298 bp
  • A to G, chromosome 3 at 98,334,549 bp
  • A to G, chromosome 3 at 157,994,678 bp
  • T to A, chromosome 4 at 107,890,129 bp
  • C to T, chromosome 4 at 156,199,939 bp
  • A to T, chromosome 5 at 101,957,388 bp
  • A to G, chromosome 5 at 109,156,847 bp
  • C to A, chromosome 5 at 123,796,104 bp
  • A to T, chromosome 7 at 3,717,638 bp
  • A to C, chromosome 7 at 13,299,069 bp
  • A to C, chromosome 7 at 44,865,470 bp
  • T to C, chromosome 7 at 64,300,615 bp
  • G to T, chromosome 7 at 109,525,620 bp
  • T to A, chromosome 8 at 45,040,555 bp
  • T to C, chromosome 8 at 117,076,177 bp
  • G to T, chromosome 9 at 79,638,485 bp
  • A to T, chromosome 9 at 123,083,623 bp
  • T to A, chromosome 10 at 127,085,150 bp
  • T to C, chromosome 10 at 129,133,526 bp
  • T to C, chromosome 11 at 60,792,976 bp
  • T to A, chromosome 11 at 72,760,296 bp
  • T to A, chromosome 11 at 110,042,988 bp
  • C to A, chromosome 12 at 41,454,231 bp
  • T to C, chromosome 12 at 110,946,343 bp
  • A to T, chromosome 13 at 70,738,829 bp
  • A to G, chromosome 13 at 100,426,096 bp
  • A to T, chromosome 13 at 101,690,523 bp
  • A to T, chromosome 14 at 43,345,493 bp
  • A to T, chromosome 14 at 50,829,230 bp
  • G to A, chromosome 14 at 93,886,757 bp
  • A to T, chromosome 14 at 101,449,209 bp
  • T to A, chromosome 15 at 12,140,548 bp
  • C to A, chromosome 15 at 44,529,264 bp
  • T to A, chromosome 15 at 66,615,630 bp
  • A to G, chromosome 16 at 16,423,901 bp
  • T to A, chromosome 16 at 32,381,763 bp
  • C to A, chromosome 16 at 89,789,561 bp
  • G to C, chromosome 17 at 28,538,766 bp
  • ACTTCTT to ACTT, chromosome 17 at 45,569,499 bp
  • A to T, chromosome 17 at 56,771,072 bp
  • A to T, chromosome 18 at 84,209,022 bp
  • A to G, chromosome 18 at 84,209,346 bp
  • T to C, chromosome 19 at 5,722,668 bp
  • T to C, chromosome 19 at 40,047,635 bp
  • T to C, chromosome 19 at 43,798,516 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0787 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038967-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.