Strain Name:
C57BL/6J-MtgxR0899Btlr/Mmmh
Stock Number:
039059-MU
Citation ID:
RRID:MMRRC_039059-MU
Other Names:
R0899 (G1), C57BL/6J-MtgxR0899Btlr
Major Collection:

Gene Information

Htr3a
Name: 5-hydroxytryptamine (serotonin) receptor 3A
Synonyms: 5-HT3 receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 15561
VEGA: 9
HGNC: HGNC:5297
Homologene: 671
Slc6a1
Name: solute carrier family 6 (neurotransmitter transporter, GABA), member 1
Synonyms: XT-1, Gabt, Xtrp1, Gat1, Gabt1, GAT-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232333
Homologene: 2290
Prdm16
Name: PR domain containing 16
Synonyms: Mel1, 5730557K01Rik, line 27, csp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 70673
Homologene: 11139
Osbpl1a
Name: oxysterol binding protein-like 1A
Synonyms: LOC328902, G430090F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 64291
Homologene: 84746
Ipo11
Name: importin 11
Synonyms: E330021B14Rik, 1700081H05Rik, 2510001A17Rik, Ranbp11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 76582
Homologene: 7089
Jam3
Name: junction adhesion molecule 3
Synonyms: JAM-3, 1110002N23Rik, Jcam3, JAM-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 83964
Homologene: 11338
Wap
Name: whey acidic protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 22373
Homologene: 137242
Afg3l2
Name: AFG3-like AAA ATPase 2
Synonyms: 2310036I02Rik, par, Emv66
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 69597
VEGA: 18
HGNC: HGNC:315
Homologene: 4947
Cbln2
Name: cerebellin 2 precursor protein
Synonyms: 6330593N19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 12405
HGNC: HGNC:1544
Homologene: 18203
Atp2b1
Name: ATPase, Ca++ transporting, plasma membrane 1
Synonyms: PMCA1, E130111D10Rik, 2810442I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67972
VEGA: 10
HGNC: HGNC:814
Homologene: 55597
Fam120a
Name: family with sequence similarity 120, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218236
VEGA: 13
Homologene: 8752
Fam3d
Name: FAM3 metabolism regulating signaling molecule D
Synonyms: EF-7, 2310076N21Rik, Oit1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 18300
VEGA: 14
Homologene: 16354
Pfkl
Name: phosphofructokinase, liver, B-type
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18641
HGNC: HGNC:8876
Homologene: 55668
Crcp
Name: calcitonin gene-related peptide-receptor component protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12909
Homologene: 40587
Myo15
Name: myosin XV
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17910
HGNC: HGNC:7594
Homologene: 56504
Cubn
Name: cubilin (intrinsic factor-cobalamin receptor)
Synonyms: D2Wsu88e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 65969
HGNC: HGNC:2548
Homologene: 37434
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Fat2
Name: FAT atypical cadherin 2
Synonyms: LOC245827, mKIAA0811, Fath2, EMI2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Astn1
Name: astrotactin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 11899
HGNC: HGNC:773
Homologene: 7233
Fbxo44
Name: F-box protein 44
Synonyms: Fbx6a, FBX30, FBG3, Fbxo6a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230903
Homologene: 13232
Myocd
Name: myocardin
Synonyms: Srfcp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 214384
Homologene: 17043
Dthd1
Name: death domain containing 1
Synonyms: Gm17384
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100322896
Homologene: 123510
Adamts1
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
Synonyms: ADAM-TS1, METH1, METH-1, ADAMTS-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 11504
HGNC: HGNC:217
Homologene: 21381
Ces2h
Name: carboxylesterase 2H
Synonyms: Gm5744
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 436059
HGNC: HGNC:1864
Homologene: 128645
Lypd11
Name: Ly6/PLAUR domain containing 11
Synonyms: Gm4763
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 210155
Olfr1026
Name: olfactory receptor 1026
Synonyms: GA_x6K02T2Q125-47402610-47403533, MOR196-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258577
Homologene: 73971
Pla2g4c
Name: phospholipase A2, group IVC (cytosolic, calcium-independent)
Synonyms: CPLA2-gamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232889
HGNC: HGNC:9037
Homologene: 115256
Fcnb
Name: ficolin B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14134
Homologene: 1518
Aqp12
Name: aquaporin 12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 208760
Homologene: 45582
Scnn1b
Name: sodium channel, nonvoltage-gated 1 beta
Synonyms: ENaC beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20277
Homologene: 133555
5031439G07Rik
Name: RIKEN cDNA 5031439G07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223739
HGNC: HGNC:1314
Homologene: 15140
Cfap43
Name: cilia and flagella associated protein 43
Synonyms: 4930428C11Rik, 4632415N18Rik, 4930463G05Rik, D19Ertd652e, Wdr96
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 100048534
Homologene: 36425
Obox5
Name: oocyte specific homeobox 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 252829
Homologene: 44937
Prkd1
Name: protein kinase D1
Synonyms: Pkcm, PKD1, Prkcm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 18760
VEGA: 12
HGNC: HGNC:9407
Homologene: 55680
Cfap61
Name: cilia and flagella associated protein 61
Synonyms: 4930529M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 78774
Wdr86
Name: WD repeat domain 86
Synonyms: 2810046M22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 269633
Homologene: 90112
Endov
Name: endonuclease V
Synonyms: A730011L01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 338371
Homologene: 15562
Olfr854
Name: olfactory receptor 854
Synonyms: GA_x6K02T2PVTD-13313295-13312357, MOR147-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258515
HGNC: HGNC:8465
Homologene: 128144
Aadacl3
Name: arylacetamide deacetylase like 3
Synonyms: LOC230883
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230883
Homologene: 28426
Tktl2
Name: transketolase-like 2
Synonyms: 4933401I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74419
Homologene: 69456
Ndst1
Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
Synonyms: glucosaminyl N-deacetylase/N-sulfotransferase 1, Hsst, 1200015G06Rik, Ndst-1, b2b2230Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 15531
VEGA: 18
HGNC: HGNC:7680
Homologene: 20386
Olfr790
Name: olfactory receptor 790
Synonyms: GA_x6K02T2PULF-11179777-11180721, MOR112-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258935
Homologene: 74101
Gtf2a1l
Name: general transcription factor IIA, 1-like
Synonyms: 1700011N16Rik, Alf, Gtf2a1lf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 71828
Homologene: 86732
Capn10
Name: calpain 10
Synonyms: Capn8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 23830
HGNC: HGNC:1477
Homologene: 36323
Igkv3-10
Name: immunoglobulin kappa variable 3-10
Synonyms: V-kappa-21B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 667924
Mrpl52
Name: mitochondrial ribosomal protein L52
Synonyms: 1110047B07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 68836
Homologene: 12286
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 92,942,629 bp
  • G to A, chromosome 1 at 93,006,610 bp
  • T to A, chromosome 1 at 158,511,109 bp
  • A to G, chromosome 2 at 13,362,328 bp
  • T to A, chromosome 2 at 28,076,779 bp
  • A to G, chromosome 2 at 76,887,985 bp
  • A to G, chromosome 2 at 85,923,387 bp
  • A to T, chromosome 2 at 146,110,096 bp
  • A to G, chromosome 4 at 144,457,114 bp
  • C to G, chromosome 4 at 148,156,269 bp
  • A to T, chromosome 4 at 154,528,909 bp
  • C to T, chromosome 5 at 24,718,007 bp
  • A to G, chromosome 5 at 62,842,928 bp
  • A to G, chromosome 5 at 130,059,831 bp
  • T to C, chromosome 6 at 70,572,916 bp
  • C to A, chromosome 6 at 114,308,132 bp
  • G to A, chromosome 7 at 13,340,679 bp
  • A to T, chromosome 7 at 15,758,875 bp
  • C to T, chromosome 7 at 24,723,312 bp
  • G to A, chromosome 7 at 121,917,715 bp
  • G to A, chromosome 8 at 66,512,347 bp
  • T to C, chromosome 8 at 105,014,550 bp
  • A to C, chromosome 9 at 19,566,547 bp
  • C to A, chromosome 9 at 27,098,957 bp
  • T to A, chromosome 9 at 48,901,452 bp
  • A to G, chromosome 10 at 78,005,439 bp
  • G to A, chromosome 10 at 99,017,031 bp
  • T to C, chromosome 10 at 129,501,432 bp
  • T to C, chromosome 11 at 6,636,725 bp
  • C to T, chromosome 11 at 55,256,225 bp
  • A to G, chromosome 11 at 60,477,185 bp
  • G to A, chromosome 11 at 65,195,192 bp
  • C to A, chromosome 11 at 119,499,593 bp
  • A to G, chromosome 12 at 50,385,193 bp
  • G to T, chromosome 13 at 48,885,743 bp
  • A to C, chromosome 13 at 106,900,816 bp
  • A to G, chromosome 14 at 8,364,863 bp
  • C to T, chromosome 14 at 54,427,084 bp
  • T to C, chromosome 15 at 84,949,258 bp
  • G to A, chromosome 16 at 85,798,052 bp
  • A to G, chromosome 17 at 88,668,724 bp
  • T to C, chromosome 18 at 12,757,690 bp
  • T to C, chromosome 18 at 60,707,882 bp
  • T to C, chromosome 18 at 67,422,977 bp
  • T to C, chromosome 18 at 86,716,752 bp
  • C to T, chromosome 19 at 47,747,994 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0899 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039059-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.