Strain Name:
C57BL/6J-MtgxR0904Btlr/Mmmh
Stock Number:
039062-MU
Citation ID:
RRID:MMRRC_039062-MU
Other Names:
R0904 (G1), C57BL/6J-MtgxR0904Btlr
Major Collection:

Gene Information

H2-D1
Name: histocompatibility 2, D region locus 1
Synonyms: H-2D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14964
Homologene: 128352
Adk
Name: adenosine kinase
Synonyms: 2310026J05Rik, 5033405D03Rik, AK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 11534
VEGA: 14
HGNC: HGNC:257
Homologene: 4891
Nfya
Name: nuclear transcription factor-Y alpha
Synonyms: Sez10, Cbf-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 18044
HGNC: HGNC:7804
Homologene: 32114
Mllt6
Name: myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6
Synonyms: Af17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 246198
HGNC: HGNC:7138
Homologene: 31347
Vangl1
Name: VANGL planar cell polarity 1
Synonyms: Lpp2, mStbm, stbm, KITENIN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229658
Homologene: 44540
Gtf3c1
Name: general transcription factor III C 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233863
HGNC: HGNC:4664
Homologene: 31040
Ss18l1
Name: SS18, nBAF chromatin remodeling complex subunit like 1
Synonyms: A230053O16Rik, CREST
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 269397
Homologene: 9191
Resf1
Name: retroelement silencing factor 1
Synonyms: GET, 2810474O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67246
Homologene: 19251
Pex5
Name: peroxisomal biogenesis factor 5
Synonyms: Pxr1, peroxisome biogenesis factor 5, ESTM1, PTS1R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19305
HGNC: HGNC:9719
Homologene: 270
Fam193a
Name: family with sequence homology 193, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231128
Homologene: 2746
Tpbg
Name: trophoblast glycoprotein
Synonyms: 5T4 oncofetal antigen, 5T4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 21983
Homologene: 4859
Lgr6
Name: leucine-rich repeat-containing G protein-coupled receptor 6
Synonyms: A530037C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329252
Homologene: 49680
Nipbl
Name: NIPBL cohesin loading factor
Synonyms: 4933421G18Rik, 4921518A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 71175
VEGA: 15
Homologene: 15850
Map1s
Name: microtubule-associated protein 1S
Synonyms: VCY2IP1, Bpy2ip1, Mtap1s, 6430517J16Rik, Map8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 270058
Homologene: 10047
Zfp268
Name: zinc finger protein 268
Synonyms: Gm13212
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 433801
Homologene: 133076
Abca13
Name: ATP-binding cassette, sub-family A (ABC1), member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268379
Homologene: 27991
Spdye4b
Name: speedy/RINGO cell cycle regulator family, member E4B
Synonyms: 4933411G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 330228
Homologene: 138445
Naip2
Name: NLR family, apoptosis inhibitory protein 2
Synonyms: Naip-rs6, Birc1b, Naip2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17948
HGNC: HGNC:7634
Homologene: 136092
Slfn10-ps
Name: schlafen 10, pseudogene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237887
Bpifb9a
Name: BPI fold containing family B, member 9A
Synonyms: 4833413D08Rik, vomeromodulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71425
Homologene: 128535
Eqtn
Name: equatorin, sperm acrosome associated
Synonyms: 4930579C15Rik, equatorin, Afaf, 1700028B15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67753
HGNC: HGNC:1359
Homologene: 75250
Unc5c
Name: unc-5 netrin receptor C
Synonyms: Unc5h3, B130051O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 22253
Homologene: 2765
Vmn1r52
Name: vomeronasal 1 receptor 52
Synonyms: VN3, V1ra7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 113849
Scai
Name: suppressor of cancer cell invasion
Synonyms: A930041I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 320271
Homologene: 15523
Fbxl6
Name: F-box and leucine-rich repeat protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 30840
VEGA: 15
Homologene: 8130
1700011L22Rik
Name: RIKEN cDNA 1700011L22 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67687
Homologene: 78034
Prx
Name: periaxin
Synonyms: L-Periaxin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 19153
Homologene: 76542
Vmn2r23
Name: vomeronasal 2, receptor 23
Synonyms: EG435916
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 435916
Homologene: 135826
Mzf1
Name: myeloid zinc finger 1
Synonyms: Znf42, Zfp98, Mzf2, Zfp121
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 109889
Homologene: 9633
Mapk10
Name: mitogen-activated protein kinase 10
Synonyms: C230008H04Rik, JNK3, p493F12, Serk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 26414
HGNC: HGNC:6872
Homologene: 56439
Trbv16
Name: T cell receptor beta, variable 16
Synonyms: Gm16776, Tcrb-V11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 100124680
9230110F15Rik
Name: RIKEN cDNA 9230110F15 gene
Synonyms:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Neurod2
Name: neurogenic differentiation 2
Synonyms: Ndrf, bHLHa1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18013
HGNC: HGNC:7763
Homologene: 4489
Dap
Name: death-associated protein
Synonyms: 4921531N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223453
HGNC: HGNC:2672
Homologene: 3235
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 134,994,010 bp
  • G to A, chromosome 2 at 39,075,152 bp
  • T to C, chromosome 2 at 154,264,225 bp
  • A to G, chromosome 2 at 180,059,354 bp
  • A to G, chromosome 3 at 102,183,994 bp
  • A to G, chromosome 3 at 141,803,840 bp
  • A to T, chromosome 4 at 94,907,655 bp
  • T to C, chromosome 4 at 145,622,175 bp
  • A to G, chromosome 5 at 34,462,143 bp
  • A to C, chromosome 5 at 95,341,327 bp
  • A to G, chromosome 5 at 102,987,280 bp
  • A to G, chromosome 5 at 143,195,668 bp
  • T to C, chromosome 6 at 41,151,847 bp
  • T to A, chromosome 6 at 90,179,464 bp
  • A to T, chromosome 6 at 123,742,135 bp
  • G to A, chromosome 6 at 124,399,937 bp
  • G to A, chromosome 6 at 149,328,269 bp
  • C to A, chromosome 7 at 13,052,771 bp
  • T to A, chromosome 7 at 27,518,294 bp
  • A to T, chromosome 7 at 125,668,842 bp
  • C to A, chromosome 8 at 70,914,188 bp
  • A to G, chromosome 8 at 79,248,489 bp
  • T to C, chromosome 9 at 35,839,070 bp
  • C to A, chromosome 9 at 85,844,564 bp
  • T to C, chromosome 11 at 9,298,740 bp
  • T to C, chromosome 11 at 83,035,409 bp
  • C to G, chromosome 11 at 97,664,998 bp
  • G to T, chromosome 11 at 98,327,321 bp
  • T to C, chromosome 13 at 100,161,854 bp
  • C to T, chromosome 13 at 100,161,860 bp
  • G to T, chromosome 14 at 21,092,428 bp
  • A to T, chromosome 15 at 8,361,718 bp
  • G to A, chromosome 15 at 31,272,380 bp
  • A to T, chromosome 15 at 76,537,083 bp
  • G to C, chromosome 17 at 35,263,861 bp
  • G to A, chromosome 17 at 48,395,787 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0904 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039062-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.