Strain Name:
C57BL/6J-MtgxR0906Btlr/Mmmh
Stock Number:
039064-MU
Citation ID:
RRID:MMRRC_039064-MU
Other Names:
R0906 (G1), C57BL/6J-MtgxR0906Btlr
Major Collection:

Gene Information

Nsd1
Name: nuclear receptor-binding SET-domain protein 1
Synonyms: KMT3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18193
VEGA: 13
Homologene: 32543
Nup205
Name: nucleoporin 205
Synonyms: 3830404O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 70699
Homologene: 45971
Slc9a8
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 8
Synonyms: NHE8, 1200006P13Rik, 6430709P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 77031
Homologene: 75041
Topbp1
Name: topoisomerase (DNA) II binding protein 1
Synonyms: D430026L04Rik, 2810429C13Rik, 1110031N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235559
Homologene: 38262
Golga1
Name: golgi autoantigen, golgin subfamily a, 1
Synonyms: golgin-97, 0710001G09Rik, 2210418B03Rik, Golgi97, awag
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 76899
HGNC: HGNC:4424
Homologene: 68223
Pikfyve
Name: phosphoinositide kinase, FYVE type zinc finger containing
Synonyms: 5230400C17Rik, Pip5k3, PipkIII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18711
Homologene: 32115
Gm14496
Name: predicted gene 14496
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 672125
Homologene: 129606
Itih5
Name: inter-alpha (globulin) inhibitor H5
Synonyms: 5430408M01Rik, 4631408O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 209378
Homologene: 57115
Lgr6
Name: leucine-rich repeat-containing G protein-coupled receptor 6
Synonyms: A530037C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329252
Homologene: 49680
Sec63
Name: SEC63-like (S. cerevisiae)
Synonyms: 5730478J10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 140740
Homologene: 5220
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Acz, Pico
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 26875
Homologene: 69111
Nuak1
Name: NUAK family, SNF1-like kinase, 1
Synonyms: B230104P22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 77976
Homologene: 8896
Naip2
Name: NLR family, apoptosis inhibitory protein 2
Synonyms: Naip-rs6, Naip2, Birc1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17948
HGNC: HGNC:7634
Homologene: 136092
Atp7b
Name: ATPase, Cu++ transporting, beta polypeptide
Synonyms: WND, Wilson protein, Atp7a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11979
HGNC: HGNC:870
Homologene: 20063
Pik3r6
Name: phosphoinositide-3-kinase regulatory subunit 5
Synonyms: p87PIKAP, p84 Pikap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 104709
Homologene: 46215
Vmn2r88
Name: vomeronasal 2, receptor 88
Synonyms: V2r13, V2r3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 669149
Homologene: 129606
Stab1
Name: stabilin 1
Synonyms: MS-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 192187
Homologene: 9035
Guf1
Name: GUF1 homolog, GTPase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231279
Homologene: 6505
Htra4
Name: HtrA serine peptidase 4
Synonyms: B430206E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 330723
Homologene: 17801
Cyp2c39
Name: cytochrome P450, family 2, subfamily c, polypeptide 39
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 13098
HGNC: HGNC:2622
Homologene: 117948
Pla2r1
Name: phospholipase A2 receptor 1
Synonyms: PLA2-I receptor, M-type receptor, Pla2g1br
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18779
HGNC: HGNC:9042
Homologene: 32016
Dcbld2
Name: discoidin, CUB and LCCL domain containing 2
Synonyms: 1700055P21Rik, Esdn, CLCP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 73379
Homologene: 12499
Tmem217
Name: transmembrane protein 217
Synonyms: EG622644, 4933413N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 71138
VEGA: 17
Homologene: 51671
Olfr398
Name: olfactory receptor 398
Synonyms: GA_x6K02T2P1NL-4141430-4140486, MOR157-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258705
Homologene: 17355
Bace2
Name: beta-site APP-cleaving enzyme 2
Synonyms: 1110059C24Rik, CEAP1, CDA13, ASP21, ALP56, BAE2, ARP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 56175
VEGA: 16
HGNC: HGNC:934
Homologene: 22696
Rgs22
Name: regulator of G-protein signalling 22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 626596
Homologene: 75047
Ttbk2
Name: tau tubulin kinase 2
Synonyms: TTK, B930008N24Rik, 2610507N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 140810
Homologene: 62795
AA986860
Name: expressed sequence AA986860
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 212439
Homologene: 49741
Slc2a5
Name: solute carrier family 2 (facilitated glucose transporter), member 5
Synonyms: GLUT5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56485
Homologene: 74459
Gm5065
Name: predicted gene 5065
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 272350
Terb1
Name: telomere repeat binding bouquet formation protein 1
Synonyms: 4930532D21Rik, Ccdc79
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 320022
Homologene: 18330
Gm6729
Name: predicted gene 6729
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 627035
VEGA: 10
Homologene: 141143
Gm4945
Name: predicted gene 4945
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 240110
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 65,253,397 bp
  • T to A, chromosome 1 at 130,737,693 bp
  • C to T, chromosome 1 at 134,994,010 bp
  • G to A, chromosome 2 at 10,249,188 bp
  • G to A, chromosome 2 at 39,047,643 bp
  • A to G, chromosome 2 at 60,514,947 bp
  • G to A, chromosome 2 at 120,783,781 bp
  • G to T, chromosome 2 at 167,434,867 bp
  • A to G, chromosome 2 at 182,000,515 bp
  • T to C, chromosome 4 at 150,142,830 bp
  • T to C, chromosome 5 at 14,676,686 bp
  • T to C, chromosome 5 at 69,566,386 bp
  • G to T, chromosome 6 at 35,236,892 bp
  • T to C, chromosome 7 at 5,359,829 bp
  • T to C, chromosome 8 at 22,027,826 bp
  • T to A, chromosome 8 at 25,037,144 bp
  • A to T, chromosome 8 at 104,452,636 bp
  • C to T, chromosome 9 at 103,328,593 bp
  • T to A, chromosome 10 at 42,801,928 bp
  • C to T, chromosome 10 at 84,375,280 bp
  • T to C, chromosome 10 at 86,540,592 bp
  • T to C, chromosome 11 at 68,536,101 bp
  • G to C, chromosome 11 at 73,983,859 bp
  • T to C, chromosome 13 at 55,277,590 bp
  • T to C, chromosome 13 at 100,161,854 bp
  • C to T, chromosome 13 at 100,161,860 bp
  • T to C, chromosome 14 at 31,145,249 bp
  • T to G, chromosome 14 at 51,418,209 bp
  • A to T, chromosome 15 at 36,103,902 bp
  • A to G, chromosome 16 at 58,455,247 bp
  • C to T, chromosome 16 at 97,356,941 bp
  • A to G, chromosome 17 at 29,526,516 bp
  • A to C, chromosome 17 at 47,042,870 bp
  • A to G, chromosome 19 at 39,510,871 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0906 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039064-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.