Strain Name:
C57BL/6J-MtgxR0907Btlr/Mmmh
Stock Number:
039065-MU
Citation ID:
RRID:MMRRC_039065-MU
Other Names:
R0907 (G1), C57BL/6J-MtgxR0907Btlr
Major Collection:

Gene Information

Dop1b
Name: DOP1 leucine zipper like protein B
Synonyms: 2610510B01Rik, Dopey2, 0610038M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 70028
VEGA: 16
HGNC: HGNC:1291
Homologene: 21068
Abl2
Name: v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
Synonyms: Abll, Arg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 11352
HGNC: HGNC:77
Homologene: 5278
Sf3b3
Name: splicing factor 3b, subunit 3
Synonyms: 1810061H24Rik, SAP130, RSE1, D8Ertd633e, 5730409A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 101943
Homologene: 6579
Hat1
Name: histone aminotransferase 1
Synonyms: KAT1, 2410071B14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 107435
HGNC: HGNC:4821
Homologene: 2701
Focad
Name: focadhesin
Synonyms: BC057079
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230393
Homologene: 9842
Ccdc191
Name: coiled-coil domain containing 191
Synonyms: 2610015P09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 212153
Homologene: 19484
Herc1
Name: HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Synonyms: D130015N03Rik, 2810449H11Rik, tbl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235439
HGNC: HGNC:4867
Homologene: 31207
Lrp6
Name: low density lipoprotein receptor-related protein 6
Synonyms: skam26Jus, skax26, Cd, ska26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16974
HGNC: HGNC:6698
Homologene: 1747
Pikfyve
Name: phosphoinositide kinase, FYVE type zinc finger containing
Synonyms: Pip5k3, 5230400C17Rik, PipkIII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18711
Homologene: 32115
Gucy1a1
Name: guanylate cyclase 1, soluble, alpha 1
Synonyms: alpha 1 sGC, sGC-alpha1, 1200016O07Rik, Gucy1a3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 60596
HGNC: HGNC:4685
Homologene: 37360
Lgr6
Name: leucine-rich repeat-containing G protein-coupled receptor 6
Synonyms: A530037C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 329252
Homologene: 49680
Fat1
Name: FAT atypical cadherin 1
Synonyms: mFat1, 2310038E12Rik, Fath
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 14107
HGNC: HGNC:3595
Homologene: 66302
Smn1
Name: survival motor neuron 1
Synonyms: SMN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 20595
Homologene: 292
Pcnx3
Name: pecanex homolog 3
Synonyms: Pcnxl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 104401
Homologene: 17000
Dcbld1
Name: discoidin, CUB and LCCL domain containing 1
Synonyms: 4631413K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 66686
Homologene: 12010
Lrp3
Name: low density lipoprotein receptor-related protein 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 435965
HGNC: HGNC:6695
Homologene: 1745
Flt3l
Name: FMS-like tyrosine kinase 3 ligand
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 14256
HGNC: HGNC:3766
Homologene: 48021
Rasgrp3
Name: RAS, guanyl releasing protein 3
Synonyms: LOC240168
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 240168
VEGA: 17
Homologene: 15019
Olfr1500
Name: olfactory receptor 1500
Synonyms: MOR212-4P, GA_x6K02T2RE5P-4160554-4159619
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258097
Homologene: 72644
Sprr3
Name: small proline-rich protein 3
Synonyms: SPR3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20766
Homologene: 135951
Mmrn1
Name: multimerin 1
Synonyms: 4921530G03Rik, Emilin4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 70945
HGNC: HGNC:7178
Homologene: 49134
Unc5c
Name: unc-5 netrin receptor C
Synonyms: Unc5h3, B130051O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 22253
Homologene: 2765
Tnni3k
Name: TNNI3 interacting kinase
Synonyms: D830019J24Rik, Cark
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 435766
Homologene: 41084
Gstm1
Name: glutathione S-transferase, mu 1
Synonyms: Gstb1, Gstb-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 14862
HGNC: HGNC:4637
Homologene: 115474
Ttll10
Name: tubulin tyrosine ligase-like family, member 10
Synonyms: 4930595O22Rik, 4833412E22Rik, Ttll5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 330010
Homologene: 51912
Afmid
Name: arylformamidase
Synonyms: formylkynureninase, formylase, Kf, 9030621K19Rik, kynurenine formamidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 71562
Homologene: 41731
Sv2c
Name: synaptic vesicle glycoprotein 2c
Synonyms: 4930527L09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 75209
Homologene: 57152
Trpt1
Name: tRNA phosphotransferase 1
Synonyms: EST-MNCb3719, TPT1, Tpt1h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 107328
VEGA: 19
Homologene: 12878
Iffo1
Name: intermediate filament family orphan 1
Synonyms: A930037G23Rik, Iffo, 4733401N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 320678
Homologene: 18706
Rd3l
Name: retinal degeneration 3-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217874
Homologene: 19151
Cep112
Name: centrosomal protein 112
Synonyms: 1700029K01Rik, 8430407H02Rik, Macoco, 1700001M19Rik, Ccdc46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 76380
Homologene: 44915
Qdpr
Name: quinoid dihydropteridine reductase
Synonyms: 2610008L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 110391
HGNC: HGNC:9752
Homologene: 271
Olfr1
Name: olfactory receptor 1
Synonyms: I54, MOR135-13, GA_x6K02T2P1NL-3556334-3555390
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258923
Homologene: 115482
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 65,202,830 bp
  • C to T, chromosome 1 at 134,994,010 bp
  • G to A, chromosome 1 at 156,629,859 bp
  • G to T, chromosome 2 at 71,420,617 bp
  • T to C, chromosome 3 at 82,111,191 bp
  • A to T, chromosome 3 at 92,457,009 bp
  • T to C, chromosome 3 at 108,017,380 bp
  • A to G, chromosome 3 at 141,789,033 bp
  • A to T, chromosome 3 at 154,941,679 bp
  • T to C, chromosome 4 at 88,278,261 bp
  • A to T, chromosome 4 at 156,036,164 bp
  • G to C, chromosome 5 at 45,439,386 bp
  • A to G, chromosome 6 at 60,973,119 bp
  • A to G, chromosome 6 at 125,153,161 bp
  • A to T, chromosome 6 at 134,507,525 bp
  • A to T, chromosome 7 at 35,203,293 bp
  • G to A, chromosome 7 at 45,132,364 bp
  • A to G, chromosome 8 at 45,026,598 bp
  • A to G, chromosome 8 at 110,811,510 bp
  • C to A, chromosome 9 at 66,433,428 bp
  • T to C, chromosome 10 at 52,261,814 bp
  • A to T, chromosome 11 at 73,395,119 bp
  • C to A, chromosome 11 at 108,570,432 bp
  • T to A, chromosome 11 at 117,835,590 bp
  • G to T, chromosome 12 at 111,980,140 bp
  • T to C, chromosome 13 at 96,088,255 bp
  • C to T, chromosome 13 at 100,127,896 bp
  • G to A, chromosome 16 at 43,915,538 bp
  • A to T, chromosome 16 at 93,801,593 bp
  • G to T, chromosome 17 at 75,509,827 bp
  • T to C, chromosome 19 at 5,671,525 bp
  • G to T, chromosome 19 at 6,998,940 bp
  • T to C, chromosome 19 at 13,827,856 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0907 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039065-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.