Strain Name:
C57BL/6J-MtgxR0909Btlr/Mmmh
Stock Number:
039067-MU
Citation ID:
RRID:MMRRC_039067-MU
Other Names:
R0909 (G1), C57BL/6J-MtgxR0909Btlr
Major Collection:

Gene Information

Sema6d
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
Synonyms: Sema6D-1, 1110067B02Rik, Sema6D-5, Sema6D-4, Sema6D-2, Sema6D-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 214968
Homologene: 16195
Lrrc2
Name: leucine rich repeat containing 2
Synonyms: 4933431K03Rik, 2400002D05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74249
Homologene: 23454
Vsnl1
Name: visinin-like 1
Synonyms: VILIP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 26950
VEGA: 12
Homologene: 2542
Ano6
Name: anoctamin 6
Synonyms: F730003B03Rik, Tmem16f, 2900059G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 105722
VEGA: 15
Homologene: 27888
Gnai3
Name: guanine nucleotide binding protein (G protein), alpha inhibiting 3
Synonyms: Galphai3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 14679
HGNC: HGNC:4387
Homologene: 55975
Nemf
Name: nuclear export mediator factor
Synonyms: 4933405E14Rik, Sdccag1, 1500011I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 66244
VEGA: 12
Homologene: 3458
Chmp5
Name: charged multivesicular body protein 5
Synonyms: chromatin modifying protein 5, 2210412K09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 76959
Homologene: 5757
Ap3s2
Name: adaptor-related protein complex 3, sigma 2 subunit
Synonyms: sigma 3B, [s]3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11778
HGNC: HGNC:571
Homologene: 100592
Vipas39
Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
Synonyms: Vipar, SPE-39
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 104799
VEGA: 12
Homologene: 41464
Ehmt2
Name: euchromatic histone lysine N-methyltransferase 2
Synonyms: D17Ertd710e, NG36, G9a, Bat8, KMT1C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 110147
Homologene: 48460
Nr6a1
Name: nuclear receptor subfamily 6, group A, member 1
Synonyms: Gcnf, NCNF, 1700113M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14536
HGNC: HGNC:7985
Homologene: 36308
Hbs1l
Name: Hbs1-like (S. cerevisiae)
Synonyms: eRFS, 2810035F15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 56422
VEGA: 10
HGNC: HGNC:4834
Homologene: 68525
Cep170b
Name: centrosomal protein 170B
Synonyms: AW555464
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217882
VEGA: 12
Homologene: 46165
Cnbd1
Name: cyclic nucleotide binding domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 435772
Homologene: 27843
Exosc9
Name: exosome component 9
Synonyms: PM/Scl-75, p5, RRP45, Pmscl1, p6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 50911
HGNC: HGNC:9137
Homologene: 3693
Msh4
Name: mutS homolog 4
Synonyms: 4930485C04Rik, mMsh4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 55993
HGNC: HGNC:7327
Homologene: 1830
Ttc16
Name: tetratricopeptide repeat domain 16
Synonyms: 1200002K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 338348
Homologene: 17011
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: D86 mRNA, fibrocystin L, PKHDL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 192190
Homologene: 16332
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380698
Homologene: 70869
Eya2
Name: EYA transcriptional coactivator and phosphatase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14049
HGNC: HGNC:3520
Homologene: 40711
Cd109
Name: CD109 antigen
Synonyms: Gov platelet alloantigens, 9930012E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235505
Homologene: 25183
Fras1
Name: Fraser extracellular matrix complex subunit 1
Synonyms: bl, E130113P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231470
Homologene: 23516
Mrpl44
Name: mitochondrial ribosomal protein L44
Synonyms: 1810030E18Rik, 5730593H20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 69163
Homologene: 11293
Frem3
Name: Fras1 related extracellular matrix protein 3
Synonyms: LOC333315
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 333315
Homologene: 35388
Heg1
Name: heart development protein with EGF-like domains 1
Synonyms: 4632417D23Rik, 5530401I02Rik, 9530025L16Rik, LOC268884
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 77446
Homologene: 35276
Rccd1
Name: RCC1 domain containing 1
Synonyms: E430018M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269955
Homologene: 16782
Fbxw21
Name: F-box and WD-40 domain protein 21
Synonyms: E330009P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320082
Homologene: 110776
Rbsn
Name: rabenosyn, RAB effector
Synonyms: Zfyve20, 5330426D11Rik, Rabenosyn-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 78287
Homologene: 41477
Wbp2nl
Name: WBP2 N-terminal like
Synonyms: PAWP, 4930521I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 74716
VEGA: 15
Homologene: 17633
Ube4a
Name: ubiquitination factor E4A
Synonyms: UFD2b, 9930123J21Rik, 4732444G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 140630
Homologene: 3517
Scg2
Name: secretogranin II
Synonyms: Chgc, SgII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20254
Homologene: 2591
Noxa1
Name: NADPH oxidase activator 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241275
Homologene: 18156
Olfr713
Name: olfactory receptor 713
Synonyms: MOR263-1, GA_x6K02T2PBJ9-9415724-9416677, P3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259036
Homologene: 17470
Vmn2r69
Name: vomeronasal 2, receptor 69
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330581
Homologene: 115466
Olfr551
Name: olfactory receptor 551
Synonyms: GA_x6K02T2PBJ9-5307445-5306498, MOR29-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258750
Homologene: 17381
Olfr95
Name: olfactory receptor 95
Synonyms: MOR263-6, GA_x6K02T2PSCP-1651760-1650822
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258506
HGNC: HGNC:8165
Homologene: 71990
H2-DMb2
Name: histocompatibility 2, class II, locus Mb2
Synonyms: H2-M beta2, H-2Mb2, H2-Mb2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15000
HGNC: HGNC:4935
Homologene: 68231
Socs5
Name: suppressor of cytokine signaling 5
Synonyms: Cish5, 1810018L08Rik, SOCS-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 56468
VEGA: 17
Homologene: 10495
1810055G02Rik
Name: RIKEN cDNA 1810055G02 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 72056
VEGA: 19
HGNC: HGNC:1174
Homologene: 11174
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 79,435,782 bp
  • G to A, chromosome 1 at 79,779,653 bp
  • A to T, chromosome 2 at 25,091,794 bp
  • T to C, chromosome 2 at 32,762,868 bp
  • A to T, chromosome 2 at 38,885,206 bp
  • T to C, chromosome 2 at 124,657,631 bp
  • A to G, chromosome 2 at 165,754,493 bp
  • A to T, chromosome 3 at 36,554,704 bp
  • G to A, chromosome 3 at 108,109,389 bp
  • G to A, chromosome 3 at 153,863,504 bp
  • A to T, chromosome 4 at 19,122,444 bp
  • C to A, chromosome 4 at 40,960,968 bp
  • T to C, chromosome 5 at 96,645,820 bp
  • G to A, chromosome 6 at 92,189,810 bp
  • T to C, chromosome 7 at 79,880,518 bp
  • A to C, chromosome 7 at 80,319,051 bp
  • C to T, chromosome 7 at 85,406,665 bp
  • A to T, chromosome 7 at 102,588,447 bp
  • T to C, chromosome 7 at 107,036,194 bp
  • A to C, chromosome 8 at 80,663,406 bp
  • T to C, chromosome 9 at 44,939,973 bp
  • A to G, chromosome 9 at 78,636,473 bp
  • C to A, chromosome 9 at 109,156,408 bp
  • T to A, chromosome 9 at 110,962,673 bp
  • A to G, chromosome 10 at 21,307,738 bp
  • T to C, chromosome 11 at 59,075,064 bp
  • A to G, chromosome 12 at 11,326,371 bp
  • T to A, chromosome 12 at 69,341,610 bp
  • T to C, chromosome 12 at 87,241,331 bp
  • A to G, chromosome 12 at 112,732,039 bp
  • T to A, chromosome 15 at 44,538,883 bp
  • G to A, chromosome 15 at 82,314,074 bp
  • T to A, chromosome 15 at 95,913,862 bp
  • C to T, chromosome 16 at 33,719,858 bp
  • C to A, chromosome 17 at 34,148,809 bp
  • T to C, chromosome 17 at 34,906,504 bp
  • T to G, chromosome 17 at 37,210,918 bp
  • T to A, chromosome 17 at 87,133,773 bp
  • T to A, chromosome 19 at 3,715,788 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0909 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039067-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.