Strain Name:
C57BL/6J-MtgxR0925Btlr/Mmmh
Stock Number:
039072-MU
Citation ID:
RRID:MMRRC_039072-MU
Other Names:
R0925 (G1), C57BL/6J-MtgxR0925Btlr
Major Collection:

Strain Information

Cdh11
Name: cadherin 11
Synonyms: osteoblast-cadherin, OB-cadherin, Cad11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12552
HGNC: HGNC:1750
Homologene: 1361
Frem2
Name: Fras1 related extracellular matrix protein 2
Synonyms: 8430406N05Rik, 6030440P17Rik, my, ne, b2b1562Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242022
Homologene: 18454
Pigv
Name: phosphatidylinositol glycan anchor biosynthesis, class V
Synonyms: D430024F16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230801
Homologene: 5354
Pdzd2
Name: PDZ domain containing 2
Synonyms: 4930537L06Rik, LOC223364, A930022H17Rik, Pdzk3, Gm21706
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 68070
Homologene: 23393
Aurka
Name: aurora kinase A
Synonyms: Ayk1, Ark1, IAK, AIRK1, aurora A, Aurora-A, Stk6, IAK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20878
Homologene: 2670
Zc3h7b
Name: zinc finger CCCH type containing 7B
Synonyms: Scrg3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20286
VEGA: 15
Homologene: 9735
Smc4
Name: structural maintenance of chromosomes 4
Synonyms: 2500002A22Rik, Smc4l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 70099
Homologene: 4015
Gabpb1
Name: GA repeat binding protein, beta 1
Synonyms: E4TF1-53, E4TF1-47, NRF2B2, NRF2B1, E4Tf1B, BABPB2, E4TF1, GABPB1-2, GABPB1-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14391
HGNC: HGNC:4074
Homologene: 7723
Cdc27
Name: cell division cycle 27
Synonyms: APC3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217232
HGNC: HGNC:1728
Homologene: 960
Myh14
Name: myosin, heavy polypeptide 14
Synonyms: NMHC II-C, 2400004E04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71960
Homologene: 23480
Rhot1
Name: ras homolog family member T1
Synonyms: Miro1, 2210403N23Rik, FLJ11040, Arht1, C430039G08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 59040
Homologene: 56803
Vps13d
Name: vacuolar protein sorting 13D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230895
Homologene: 15583
Ubr3
Name: ubiquitin protein ligase E3 component n-recognin 3
Synonyms: 4833421P10Rik, A130030D10Rik, 1110059H15Rik, Zfp650
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68795
Homologene: 52092
Dnajb6
Name: DnaJ heat shock protein family (Hsp40) member B6
Synonyms: Mrj, mDj4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 23950
Homologene: 38058
Nupl1
Name: nucleoporin like 1
Synonyms: 1700017F11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71844
VEGA: 14
Homologene: 40924
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 94109
Homologene: 69536
Itgam
Name: integrin alpha M
Synonyms: complement component receptor 3 alpha, CD11B (p170), Mac-1 alpha, Mac-1, complement receptor type 3, CR3, CD11b/CD18, Mac-1a, F730045J24Rik, Ly-40, Cd11b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16409
HGNC: HGNC:6149
Homologene: 526
Zcchc14
Name: zinc finger, CCHC domain containing 14
Synonyms: Bdg29
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 142682
Homologene: 9037
Spta1
Name: spectrin alpha, erythrocytic 1
Synonyms: Spna-1, erythroid, ihj, Spna1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20739
Homologene: 74460
Klk1
Name: kallikrein 1
Synonyms: mGk-6, 0610007D04Rik, Klk6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16612
Homologene: 68141
Dock10
Name: dedicator of cytokinesis 10
Synonyms: Jr5, Jr4, ZIZ3, 9330153B10Rik, A630054M16Rik, Zizimin3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 210293
Homologene: 45952
Scara5
Name: scavenger receptor class A, member 5
Synonyms: 4932433F15Rik, 4933425F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71145
Homologene: 12556
Tdrd7
Name: tudor domain containing 7
Synonyms: 5730495N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100121
Homologene: 8618
Abcc9
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 9
Synonyms: SUR2B, SUR2A, Sur2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 20928
HGNC: HGNC:60
Homologene: 56521
Adam34l
Name: a disintegrin and metallopeptidase domain 34 like
Synonyms: Gm5346
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 384813
Homologene: 78104
Dis3l
Name: DIS3 like exosome 3'-5' exoribonuclease
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 213550
Homologene: 15797
Myo1f
Name: myosin IF
Synonyms: C330006B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17916
HGNC: HGNC:7600
Homologene: 56276
Adam5
Name: a disintegrin and metallopeptidase domain 5
Synonyms: tMDCII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11499
HGNC: HGNC:212
Homologene: 49138
Elmod3
Name: ELMO/CED-12 domain containing 3
Synonyms: ELMOD3, RBM29, C330008I15Rik, Rbed1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232089
Homologene: 12978
Or5p81
Name: olfactory receptor family 5 subfamily P member 81
Synonyms: GA_x6K02T2PBJ9-10997715-10998659, MOR204-34, Olfr510
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258308
Prmt8
Name: protein arginine N-methyltransferase 8
Synonyms: Hrmt1l3, Hrmt1l4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 381813
HGNC: HGNC:5188
Homologene: 76124
Fam227a
Name: family with sequence similarity 227, member A
Synonyms: 4933432B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 75729
Homologene: 123434
Hormad2
Name: HORMA domain containing 2
Synonyms: 4930529M09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 75828
Homologene: 45130
Dennd3
Name: DENN/MADD domain containing 3
Synonyms: E030003N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 105841
Homologene: 28254
Eme1
Name: essential meiotic structure-specific endonuclease 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268465
Homologene: 16123
Lin37
Name: lin-37 DREAM MuvB core complex component
Synonyms: 1810054G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 75660
Homologene: 12616
Map2k1
Name: mitogen-activated protein kinase kinase 1
Synonyms: MAP kinase kinase 1, Prkmk1, Mek1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 26395
HGNC: HGNC:6840
Homologene: 2063
1700021F07Rik
Name: RIKEN cDNA 1700021F07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 72221
Homologene: 82371
Pak1ip1
Name: PAK1 interacting protein 1
Synonyms: 5830431I15Rik, 5930415H02Rik, p21-activated protein kinase-interacting protein 1, PIP1, Gdpd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 68083
Homologene: 39574
Wdfy2
Name: WD repeat and FYVE domain containing 2
Synonyms: B130024L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 268752
VEGA: 14
Homologene: 14188
C2cd4c
Name: C2 calcium-dependent domain containing 4C
Synonyms: LOC237397, 4932409I22Rik, Fam148c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237397
VEGA: 10
Homologene: 19012
Gmnc
Name: geminin coiled-coil domain containing
Synonyms: LOC239789, LOC385639, Gm606
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239789
VEGA: 16
Homologene: 79940
H2-M11
Name: histocompatibility 2, M region locus 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224754
Homologene: 52241
Gpr153
Name: G protein-coupled receptor 153
Synonyms: 1110065N12Rik, PGR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100129
Homologene: 18662
Hemgn
Name: hemogen
Synonyms: EDAG, 4921524M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 93966
Homologene: 14223
Or52j3
Name: olfactory receptor family 52 subfamily J member 3
Synonyms: GA_x6K02T2PBJ9-5902266-5903204, MOR0-3P, MOR32-13, MOR0-3P, Olfr1525-ps1, Olfr592
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 404317
Homologene: 66215
Iqcf6
Name: IQ motif containing F6
Synonyms: 100041096
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 100041096
Homologene: 67808
Rsl1d1
Name: ribosomal L1 domain containing 1
Synonyms: 2410005K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 66409
Homologene: 41052
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 80,536,940 bp
  • G to A, chromosome 1 at 174,174,426 bp
  • T to C, chromosome 2 at 69,956,112 bp
  • T to A, chromosome 2 at 126,652,265 bp
  • T to C, chromosome 2 at 172,370,387 bp
  • T to A, chromosome 2 at 173,526,074 bp
  • T to C, chromosome 3 at 53,653,973 bp
  • T to A, chromosome 3 at 69,006,215 bp
  • C to A, chromosome 4 at 46,025,758 bp
  • T to A, chromosome 4 at 46,397,049 bp
  • T to C, chromosome 4 at 133,662,649 bp
  • T to G, chromosome 4 at 145,156,551 bp
  • A to G, chromosome 4 at 152,281,874 bp
  • A to T, chromosome 5 at 29,752,400 bp
  • A to T, chromosome 6 at 72,568,938 bp
  • T to C, chromosome 6 at 127,697,813 bp
  • A to T, chromosome 6 at 142,685,188 bp
  • T to C, chromosome 7 at 30,557,191 bp
  • T to A, chromosome 7 at 44,228,816 bp
  • T to A, chromosome 7 at 44,655,695 bp
  • T to A, chromosome 7 at 103,186,823 bp
  • C to T, chromosome 7 at 108,668,193 bp
  • T to C, chromosome 7 at 128,112,238 bp
  • A to G, chromosome 8 at 16,710,618 bp
  • T to C, chromosome 8 at 24,812,425 bp
  • T to C, chromosome 8 at 43,626,303 bp
  • T to A, chromosome 8 at 102,634,724 bp
  • A to T, chromosome 8 at 121,606,173 bp
  • A to G, chromosome 9 at 64,204,495 bp
  • A to T, chromosome 9 at 64,341,130 bp
  • A to G, chromosome 9 at 106,627,301 bp
  • T to C, chromosome 10 at 79,612,750 bp
  • G to A, chromosome 11 at 4,427,297 bp
  • T to C, chromosome 11 at 80,250,349 bp
  • T to C, chromosome 11 at 94,650,732 bp
  • A to G, chromosome 11 at 104,526,049 bp
  • T to A, chromosome 13 at 41,004,905 bp
  • T to C, chromosome 14 at 60,220,141 bp
  • A to T, chromosome 14 at 62,930,226 bp
  • AC to ACC, chromosome 14 at 65,762,718 bp
  • C to T, chromosome 15 at 12,399,270 bp
  • T to G, chromosome 15 at 73,533,435 bp
  • A to T, chromosome 15 at 79,620,805 bp
  • T to C, chromosome 15 at 81,785,981 bp
  • A to T, chromosome 16 at 11,199,689 bp
  • A to G, chromosome 16 at 26,960,423 bp
  • A to T, chromosome 17 at 33,578,133 bp
  • T to C, chromosome 17 at 36,547,461 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0925 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039072-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.